All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
Juliane Zemdegs, Hugo Martin, Hiranya Pintana, Sebastien Bullich, Stella Manta, Marie A Marqués, Cédric Moro, Sophie Layé, Fabien Ducrocq, Nipon Chattipakorn, Siriporn C Chattipakorn, Claire Rampon, Luc Pénicaud, Xavier Fioramonti, Bruno P Guiar. Metformin Promotes Anxiolytic and Antidepressant-Like Responses in Insulin-Resistant Mice by Decreasing Circulating Branched-Chain Amino Acids. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 30. 2020-06-17. PMID:31160539. our results indicated that hfd-fed mice displayed impairment in the electrical activity of dorsal raphe 5-ht neurons, attenuated hippocampal extracellular 5-ht concentrations and anxiety, one of the most visible and early symptoms of depression. 2020-06-17 2023-08-13 mouse
Pollyana C Leal, José Marcos M Bispo, Rovena C G J Engelberth, Kayo Diogenes de A Silva, Ywlliane R Meurer, Alessandra M Ribeiro, Regina H Silva, Murilo Marchioro, José R Santo. Serotonergic dysfunction in a model of parkinsonism induced by reserpine. Journal of chemical neuroanatomy. vol 96. 2020-06-15. PMID:30597197. conversely, a significant increase of 5-ht immunoreactivity was found in mpfc and dorsal raphe nucleus (drn) in animals submitted to mt when compared to st exposure. 2020-06-15 2023-08-13 rat
Abdellatif Abbaoui, Halima Gamran. Obvious anxiogenic-like effects of subchronic copper intoxication in rats, outcomes on spatial learning and memory and neuromodulatory potential of curcumin. Journal of chemical neuroanatomy. vol 96. 2020-06-15. PMID:30611899. in cu-exposed rats, we noted a significant increased innervation of 5ht in dorsal raphe nucleus and basolateral amygdala (bla) outputs; this was correlated with an anxiogenic-like effect in rats subjected to elevated plus-maze test. 2020-06-15 2023-08-13 rat
Catherine A Marcinkiewcz, Gabrielle Bierlein-De La Rosa, Cayce E Dorrier, Mackenzie McKnight, Jeffrey F DiBerto, Dipanwati Pati, Carol A Gianessi, Olivia J Hon, Greg Tipton, Zoe A McElligott, Eric Delpire, Thomas L Kas. Sex-Dependent Modulation of Anxiety and Fear by 5-HT ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:31140276. efferent 5-ht projections from the dorsal raphe nucleus (drn) to the bed nucleus of the stria terminalis (bnst) are generally thought to enhance anxiety and aversive learning by activating 5-ht 2020-06-11 2023-08-13 Not clear
Derya Sargin, Ha-Seul Jeoung, Nathalie M Goodfellow, Evelyn K Lamb. Serotonin Regulation of the Prefrontal Cortex: Cognitive Relevance and the Impact of Developmental Perturbation. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:31259523. optogenetic and chemogenetic manipulations of dorsal raphe 5-ht neurons reveal that serotonin has a greater impact on executive function than previously appreciated. 2020-06-11 2023-08-13 Not clear
Abdelaati El Khiat, Lahcen Tamegart, Ahmed Draoui, Radouane El Fari, Souad Sellami, Hanane Rais, Omar El Hiba, Halima Gamran. Kinetic deterioration of short memory in rat with acute hepatic encephalopathy: Involvement of astroglial and neuronal dysfunctions. Behavioural brain research. vol 367. 2020-06-08. PMID:30928460. while for the behavioral study, we used t-maze test to assess short working memory using the percentage of alternation behavior, together with an immunohistochemical analysis of the glial fibrillary acidic protein (gfap) as the key marker of astrocytes in the hippocampus, as well as serotonin (5-ht) for 5-htergic neurons within the dorsal raphe nucleus (drn). 2020-06-08 2023-08-13 rat
Widya Adidharma, Sean P Deats, Tomoko Ikeno, Jack W Lipton, Joseph S Lonstein, Lily Ya. Orexinergic modulation of serotonin neurons in the dorsal raphe of a diurnal rodent, Arvicanthis niloticus. Hormones and behavior. vol 116. 2020-04-14. PMID:31445011. orexinergic modulation of serotonin neurons in the dorsal raphe of a diurnal rodent, arvicanthis niloticus. 2020-04-14 2023-08-13 rat
Widya Adidharma, Sean P Deats, Tomoko Ikeno, Jack W Lipton, Joseph S Lonstein, Lily Ya. Orexinergic modulation of serotonin neurons in the dorsal raphe of a diurnal rodent, Arvicanthis niloticus. Hormones and behavior. vol 116. 2020-04-14. PMID:31445011. the objective of the present study was to test the hypothesis that the serotonin (5-ht) system of the dorsal raphe nucleus (drn) is a downstream target through which orexin potentially manifests its role in affective states. 2020-04-14 2023-08-13 rat
Romana Koprdova, Kristina Csatlosova, Barbora Durisova, Eszter Bogi, Magdalena Majekova, Eliyahu Dremencov, Mojmir Mac. Electrophysiology and Behavioral Assessment of the New Molecule SMe1EC2M3 as a Representative of the Future Class of Triple Reuptake Inhibitors. Molecules (Basel, Switzerland). vol 24. issue 23. 2020-04-14. PMID:31757051. electrophysiological investigations showed that sme1ec2m3 dose-dependently suppressed the excitability of 5-ht neurons of the dorsal raphe nucleus (drn), norepinephrine neurons of the locus coeruleus (lc), and dopamine neurons of the ventral tegmental area (vta). 2020-04-14 2023-08-13 Not clear
Hui-Ling Wang, Shiliang Zhang, Jia Qi, Huikun Wang, Roger Cachope, Carlos A Mejias-Aponte, Jorge A Gomez, Gabriel E Mateo-Semidey, Gerard M J Beaudoin, Carlos A Paladini, Joseph F Cheer, Marisela Morale. Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons. Cell reports. vol 26. issue 5. 2020-03-13. PMID:30699344. dorsal raphe (dr) serotonin neurons provide a major input to the ventral tegmental area (vta). 2020-03-13 2023-08-13 Not clear
M Soiza-Reilly, F J Meye, J Olusakin, L Telley, E Petit, X Chen, M Mameli, D Jabaudon, J-Y Sze, P Gaspa. SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior. Molecular psychiatry. vol 24. issue 5. 2020-03-03. PMID:30279456. pfc-sert+ neurons establish glutamatergic synapses with subcortical targets, including the serotonin (5-ht) and gaba neurons of the dorsal raphe nucleus (drn). 2020-03-03 2023-08-13 mouse
Ya Wang, Yang Liu, Jianwei Xiong, Tingting Di, Zihao Yuan, Jie Wu, Ling Che. Reduced serotonin impairs long-term depression in basolateral amygdala complex and causes anxiety-like behaviors in a mouse model of perimenopause. Experimental neurology. vol 321. 2020-02-28. PMID:31377402. serotonin (5-ht) synthesis in dorsal raphe nucleus (drn) and serotonergic afferents to basolateral amygdala complex (bla) were reduced in vcd-mice, which were recovered by the supplement e2. 2020-02-28 2023-08-13 mouse
Jin Zhang, Shuxuan Lv, Guoyi Tang, Guanyun Bian, Yaxin Yang, Ruotong Li, Jie Yang, Jian Li. Activation of calcium-impermeable GluR2-containing AMPA receptors in the lateral habenula produces antidepressant-like effects in a rodent model of Parkinson's disease. Experimental neurology. vol 322. 2020-02-24. PMID:31499061. we further found that intra-lhb injection of (s)-ampa excited dopaminergic neurons in the anterior ventral tegmental area (avta) and serotonergic neurons in the dorsal raphe nucleus (drn), which increased release of da and 5-ht in the medial prefrontal cortex (mpfc), while nbqx induced the opposite effects. 2020-02-24 2023-08-13 rat
Daniel F Cardozo Pinto, Hongbin Yang, Iskra Pollak Dorocic, Johannes W de Jong, Vivian J Han, James R Peck, Yichen Zhu, Christine Liu, Kevin T Beier, Marten P Smidt, Stephan Lamme. Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe. Nature communications. vol 10. issue 1. 2020-02-04. PMID:31604921. the dorsal raphe (dr) is a heterogeneous nucleus containing dopamine (da), serotonin (5ht), γ-aminobutyric acid (gaba) and glutamate neurons. 2020-02-04 2023-08-13 mouse
Sergio Vegas-Suarez, Elena Paredes-Rodriguez, Asier Aristieta, Jose V Lafuente, Cristina Miguelez, Luisa Uged. Dysfunction of serotonergic neurons in Parkinson's disease and dyskinesia. International review of neurobiology. vol 146. 2020-02-03. PMID:31349930. the main population of 5-ht neurons is located in the dorsal raphe nuclei (drn), which provides extensive innervation to almost the entire neuroaxis and controls multiple functions in the brain. 2020-02-03 2023-08-13 Not clear
Ruth E Grahn, Brian A Kalman, Jennifer A Vlasaty, Jaclyn A Perna, Christine Nevins-Herbert, Stephanie M Patton, Leah K Bariso. Effects of plus-maze experience and chlordiazepoxide on anxiety-like behavior and serotonin neural activity in the dorsal raphe nucleus in rats. Behavioural pharmacology. vol 30. issue 2 and 3-Spec Issue. 2020-01-06. PMID:30169377. effects of plus-maze experience and chlordiazepoxide on anxiety-like behavior and serotonin neural activity in the dorsal raphe nucleus in rats. 2020-01-06 2023-08-13 rat
Ruth E Grahn, Brian A Kalman, Jennifer A Vlasaty, Jaclyn A Perna, Christine Nevins-Herbert, Stephanie M Patton, Leah K Bariso. Effects of plus-maze experience and chlordiazepoxide on anxiety-like behavior and serotonin neural activity in the dorsal raphe nucleus in rats. Behavioural pharmacology. vol 30. issue 2 and 3-Spec Issue. 2020-01-06. PMID:30169377. regions of the dorsal raphe nucleus (drn) were examined in male sprague-dawley rats using c-fos and serotonin immunohistochemistry following a single exposure, a second exposure or no exposure to the epm. 2020-01-06 2023-08-13 rat
M Neus Fullana, Esther Ruiz-Bronchal, Albert Ferrés-Coy, Elena Juárez-Escoto, Francesc Artigas, Analia Bortolozz. Regionally selective knockdown of astroglial glutamate transporters in infralimbic cortex induces a depressive phenotype in mice. Glia. vol 67. issue 6. 2019-12-30. PMID:30635928. intra-il glast or glt-1 knockdown markedly reduced serotonin (5-ht) release in the dorsal raphe nucleus (dr) and induced an overall reduction of brain-derived neurotrophic factor (bdnf) expression in ipsilateral and contralateral hemispheres. 2019-12-30 2023-08-13 mouse
Caleb J Browne, Andrew R Abela, Duong Chu, Zhaoxia Li, Xiaodong Ji, Evelyn K Lambe, Paul J Fletche. Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30420603. dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. 2019-11-25 2023-08-13 mouse
Caleb J Browne, Andrew R Abela, Duong Chu, Zhaoxia Li, Xiaodong Ji, Evelyn K Lambe, Paul J Fletche. Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30420603. here, we used an optogenetic approach to isolate the contribution of dorsal raphe nucleus (drn) 5-ht neurons and 5-ht innervation of the mesolimbic dopamine (da) system to motivated behavior in mice. 2019-11-25 2023-08-13 mouse