| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caleb J Browne, Andrew R Abela, Duong Chu, Zhaoxia Li, Xiaodong Ji, Evelyn K Lambe, Paul J Fletche. Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30420603. |
dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. |
2019-11-25 |
2023-08-13 |
mouse |
| Caleb J Browne, Andrew R Abela, Duong Chu, Zhaoxia Li, Xiaodong Ji, Evelyn K Lambe, Paul J Fletche. Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30420603. |
here, we used an optogenetic approach to isolate the contribution of dorsal raphe nucleus (drn) 5-ht neurons and 5-ht innervation of the mesolimbic dopamine (da) system to motivated behavior in mice. |
2019-11-25 |
2023-08-13 |
mouse |
| R. Schreiber, J. De Vr. Neuroanatomical basis for the antidepressant-like effects of the 5-HT(1A) receptor agonists 8-OH-DPAT and ipsapirone in the rat forced swimming test. Behavioural pharmacology. vol 4. issue 6. 2019-11-20. PMID:11224231. |
or local application into the dorsal raphe nucleus (drn), a brain area rich in presynaptic 5-ht(1a) receptors, resulted in a parallel shift of the dose-response curve to the left (id(50) 5.1 and 3.9µg/rat, respectively). |
2019-11-20 |
2023-08-12 |
rat |
| Constantino Sotelo, Béatrice Cholley, Salah El Mestikawy, Henri Gozlan, Michel Hamo. Direct Immunohistochemical Evidence of the Existence of 5-HT1A Autoreceptors on Serotoninergic Neurons in the Midbrain Raphe Nuclei. The European journal of neuroscience. vol 2. issue 12. 2019-11-20. PMID:12106075. |
double immunohistochemical staining using the anti-5-ht1a receptor antibodies and an anti-serotonin (5-ht) antiserum showed that all the 5-ht1a receptor immunoreactive neurons in the dorsal raphe, and the vast majority of them in the median raphe, are serotoninergic neurons. |
2019-11-20 |
2023-08-12 |
Not clear |
| Elyse C Dankoski, Susan Carroll, Robert Mark Wightma. Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26749030. |
acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. |
2019-11-20 |
2023-08-13 |
mouse |
| Elyse C Dankoski, Susan Carroll, Robert Mark Wightma. Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26749030. |
the onset of antidepressant effects also coincides with desensitization of somatodendritic serotonin autoreceptors in the dorsal raphe nucleus (drn), suggesting that disrupting inhibitory feedback within the serotonin system may contribute to the therapeutic effects of ssris. |
2019-11-20 |
2023-08-13 |
mouse |
| Elyse C Dankoski, Susan Carroll, Robert Mark Wightma. Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. Journal of neurochemistry. vol 136. issue 6. 2019-11-20. PMID:26749030. |
in this work, stimulations of the dorsal raphe nucleus (drn) evoke serotonin release that is recorded in the substantia nigra pars reticulata (snpr) using in vivo fast-scan cyclic voltammetry. |
2019-11-20 |
2023-08-13 |
mouse |
| Wenjie Zhou, Yan Jin, Qian Meng, Xia Zhu, Tongjian Bai, Yanghua Tian, Yu Mao, Likui Wang, Wen Xie, Hui Zhong, Na Zhang, Min-Hua Luo, Wenjuan Tao, Haitao Wang, Jie Li, Juan Li, Ben-Sheng Qiu, Jiang-Ning Zhou, Xiangyao Li, Han Xu, Kai Wang, Xiaochu Zhang, Yong Liu, Gal Richter-Levin, Lin Xu, Zhi Zhan. A neural circuit for comorbid depressive symptoms in chronic pain. Nature neuroscience. vol 22. issue 10. 2019-11-05. PMID:31451801. |
here we identify a novel pathway involving 5-hydroxytryptamine (5-ht) projections from the dorsal raphe nucleus (5-ht |
2019-11-05 |
2023-08-13 |
Not clear |
| Ayesha Sengupta, Andrew Holme. A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory. Neuron. vol 103. issue 3. 2019-10-31. PMID:31204082. |
a discrete dorsal raphe to basal amygdala 5-ht circuit calibrates aversive memory. |
2019-10-31 |
2023-08-13 |
Not clear |
| Ayesha Sengupta, Andrew Holme. A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory. Neuron. vol 103. issue 3. 2019-10-31. PMID:31204082. |
using convergent anatomical and functional approaches, we interrogate the contribution to fear of basal amygdala (ba) 5-ht inputs from the dorsal raphe nucleus (drn). |
2019-10-31 |
2023-08-13 |
Not clear |
| Michael V Baratta, Nathan R Leslie, Isabella P Fallon, Samuel D Dolzani, Lauren E Chun, Andrew M Tamalunas, Linda R Watkins, Steven F Maie. Behavioural and neural sequelae of stressor exposure are not modulated by controllability in females. The European journal of neuroscience. vol 47. issue 8. 2019-10-30. PMID:29359831. |
in separate experiments, behavioural (juvenile social exploration, fear and shuttle box escape) and neurochemical (activation of dorsal raphe serotonin and dorsal raphe-projecting prelimbic neurons) outcomes, which are sensitive to the dimension of control in males, were assessed. |
2019-10-30 |
2023-08-13 |
rat |
| Hui-Ai Zhang, Nan Sang, Xian Ge, Qian Huang, Xue-Liang Li, Jie Sh. Nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-HT neurons in male maternally separated rats. Scientific reports. vol 8. issue 1. 2019-10-10. PMID:29921870. |
nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-ht neurons in male maternally separated rats. |
2019-10-10 |
2023-08-13 |
rat |
| Hui-Ai Zhang, Nan Sang, Xian Ge, Qian Huang, Xue-Liang Li, Jie Sh. Nesfatin-1 in the dorsal raphe nucleus influences visceral sensitivity via 5-HT neurons in male maternally separated rats. Scientific reports. vol 8. issue 1. 2019-10-10. PMID:29921870. |
nesfatin-1, a satiety molecule processed from nucleobindin2 (nucb2), is implicated in visceral hypersensitivity in rats and colocalized with 5-hydroxytryptamine (5-ht) in the dorsal raphe nucleus (drn). |
2019-10-10 |
2023-08-13 |
rat |
| Honghai Zhang, Haiting Zhao, Chang Zeng, Christa Van Dort, Carl L Faingold, Norman E Taylor, Ken Solt, Hua-Jun Fen. Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model. Neurobiology of disease. vol 110. 2019-09-06. PMID:29141182. |
optogenetic activation of 5-ht neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the dba/1 mouse sudep model. |
2019-09-06 |
2023-08-13 |
mouse |
| Honghai Zhang, Haiting Zhao, Chang Zeng, Christa Van Dort, Carl L Faingold, Norman E Taylor, Ken Solt, Hua-Jun Fen. Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model. Neurobiology of disease. vol 110. 2019-09-06. PMID:29141182. |
we hypothesized that the dorsal raphe (dr), which sends 5-ht projections to the forebrain, is implicated in s-ira. |
2019-09-06 |
2023-08-13 |
mouse |
| Haiyan Li, Chihiro Ishikawa, Takashi Shig. Effects of postnatal handling on adult behavior and brain mRNA expression of serotonin receptor, brain-derived neurotrophic factor and GABA-A receptor subunit. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 68. 2019-08-06. PMID:29678562. |
next, to elucidate mechanisms underlying the behavioral effects, we evaluated mrna expression of the serotonin 1a (5-ht1a) receptor, brain-derived neurotrophic factor (bdnf), and gaba-a receptor subunits in the medial prefrontal cortex, amygdala, dorsal and ventral hippocampi, and dorsal raphe nucleus by quantitative rt-pcr, since these genes and brain regions have been shown to be involved in cognition and emotion. |
2019-08-06 |
2023-08-13 |
mouse |
| Changwoo Seo, Akash Guru, Michelle Jin, Brendan Ito, Brianna J Sleezer, Yi-Yun Ho, Elias Wang, Christina Boada, Nicholas A Krupa, Durgaprasad S Kullakanda, Cynthia X Shen, Melissa R Warde. Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. Science (New York, N.Y.). vol 363. issue 6426. 2019-08-01. PMID:30705194. |
intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. |
2019-08-01 |
2023-08-13 |
mouse |
| Changwoo Seo, Akash Guru, Michelle Jin, Brendan Ito, Brianna J Sleezer, Yi-Yun Ho, Elias Wang, Christina Boada, Nicholas A Krupa, Durgaprasad S Kullakanda, Cynthia X Shen, Melissa R Warde. Intense threat switches dorsal raphe serotonin neurons to a paradoxical operational mode. Science (New York, N.Y.). vol 363. issue 6426. 2019-08-01. PMID:30705194. |
in mice, we found that stimulation of dorsal raphe serotonin neurons suppressed movement in low- and moderate-threat environments but induced escape behavior in high-threat environments, and that movement-related dorsal raphe serotonin neural dynamics inverted in high-threat environments. |
2019-08-01 |
2023-08-13 |
mouse |
| Tomoaki M Kato, Mie Kubota-Sakashita, Noriko Fujimori-Tonou, Fumihito Saitow, Satoshi Fuke, Akira Masuda, Shigeyoshi Itohara, Hidenori Suzuki, Tadafumi Kat. Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder. Molecular psychiatry. vol 23. issue 10. 2019-07-31. PMID:29892051. |
dorsal raphe neurons in the heterozygous cko showed hyperexcitability, along with enhanced serotonin turnover in the nucleus accumbens and upregulation of maob in dorsal raphe. |
2019-07-31 |
2023-08-13 |
mouse |
| Thomas R Barber, Ludovica Griffanti, Kinan Muhammed, Daniel S Drew, Kevin M Bradley, Daniel R McGowan, Marie Crabbe, Christine Lo, Clare E Mackay, Masud Husain, Michele T Hu, Johannes C Klei. Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus. Brain : a journal of neurology. vol 141. issue 10. 2019-07-05. PMID:30212839. |
apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus. |
2019-07-05 |
2023-08-13 |
Not clear |