All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
Sudhakar Selvaraj, Chris Walker, Danilo Arnone, Bo Cao, Paul Faulkner, Philip J Cowen, Jonathan P Roiser, Oliver Howe. Effect of Citalopram on Emotion Processing in Humans: A Combined 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 3. 2018-11-20. PMID:28776580. presynaptic dorsal raphe neuron (drn) 5-ht 2018-11-20 2023-08-13 Not clear
M Allie Holschbach, Erika M Vitale, Joseph S Lonstei. Serotonin-specific lesions of the dorsal raphe disrupt maternal aggression and caregiving in postpartum rats. Behavioural brain research. vol 348. 2018-11-05. PMID:29653128. however, the effects on all these behaviors of permanently disrupting serotonin signaling from one of its primary sources, the dorsal raphe nucleus (dr), have not been examined in detail. 2018-11-05 2023-08-13 rat
Juraj Culman, Stephan Mühlenhoff, Annegret Blume, Jürgen Hedderich, Ulf Lützen, Stephen P Hunt, Nadia M J Rupniak, Yi Zha. The Hypothalamic-Pituitary-Adrenal Axis and Serotonin Metabolism in Individual Brain Nuclei of Mice with Genetic Disruption of the NK1 Receptor Exposed to Acute Stress. Cellular and molecular neurobiology. vol 38. issue 6. 2018-10-25. PMID:29948553. in the dorsal raphe nucleus (drn), basal 5-ht turnover was increased in nk1r-/- mice and a 15 min stress further magnified 5-ht utilisation in this region. 2018-10-25 2023-08-13 mouse
Dasiel O Borroto-Escuela, Manuel Narváez, Patrizia Ambrogini, Luca Ferraro, Ismel Brito, Wilber Romero-Fernandez, Yuniesky Andrade-Talavera, Antonio Flores-Burgess, Carmelo Millon, Belen Gago, Jose Angel Narvaez, Yuji Odagaki, Miklos Palkovits, Zaida Diaz-Cabiale, Kjell Fux. Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment. Molecules (Basel, Switzerland). vol 23. issue 6. 2018-10-22. PMID:29865267. the 5-ht1a⁻fgfr1 heteroreceptor complexes were involved in synergistically enhancing neuroplasticity in the hippocampus and in the dorsal raphe 5-ht nerve cells. 2018-10-22 2023-08-13 rat
Dasiel O Borroto-Escuela, Manuel Narváez, Patrizia Ambrogini, Luca Ferraro, Ismel Brito, Wilber Romero-Fernandez, Yuniesky Andrade-Talavera, Antonio Flores-Burgess, Carmelo Millon, Belen Gago, Jose Angel Narvaez, Yuji Odagaki, Miklos Palkovits, Zaida Diaz-Cabiale, Kjell Fux. Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment. Molecules (Basel, Switzerland). vol 23. issue 6. 2018-10-22. PMID:29865267. this may result in maintained inhibition of hippocampal pyramidal nerve cell and dorsal raphe 5-ht nerve cell firing. 2018-10-22 2023-08-13 rat
Seungrie Han, Soo Hyun Yang, Jin Yong Kim, Seojung Mo, Esther Yang, Ki Myung Song, Byung-Joo Ham, Naguib Mechawar, Gustavo Turecki, Hyun Woo Lee, Hyun Ki. Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Scientific reports. vol 7. issue 1. 2018-09-05. PMID:28420875. to determine whether habenular cholinergic signaling is associated with regulation of dopamine neurons in the ventral tegmental area (vta) and serotonin neurons in the dorsal raphe nucleus (drn), we used chat::cre transgenic mice expressing the designer receptors exclusively activated by designer drugs (dreadd). 2018-09-05 2023-08-13 mouse
Ryan P Vetreno, Yesha Patel, Urvi Patel, T Jordan Walter, Fulton T Crew. Adolescent intermittent ethanol reduces serotonin expression in the adult raphe nucleus and upregulates innate immune expression that is prevented by exercise. Brain, behavior, and immunity. vol 60. 2018-08-16. PMID:27647531. using a wistar rat model of adolescent intermittent ethanol (aie; 5.0g/kg, i.g., 2-day on/2-day off from postnatal day [p]25 to p55), we found a loss of dorsal raphe nucleus (drn) serotonin (5-ht)-immunoreactive (+ir) neurons that persisted from late adolescence (p56) into adulthood (p220). 2018-08-16 2023-08-13 human
Wang-Hua Jia, Wen-Ying Chi, Chao Lou, Gui-Zhi Wan. [Effect of Electroacupuncture Intervention on β-endorphin Levels of Hypothalamus and Spinal Cord Tissues in Rats with Pelmatic Incisional Pain]. Zhen ci yan jiu = Acupuncture research. vol 41. issue 3. 2018-07-13. PMID:29071910. to observe the effect of electroacupuncture (ea) intervention on pain thresholds (pt) and contents of β-endorphin (ep) in the hypothalamus and spinal cord, and the expression of 5-ht in the dorsal raphe nucleus(drn)in rats with pelmatic incisional pain, so as to investigate the underlying mechanisms of acupuncture in reducing post-operative pain. 2018-07-13 2023-08-13 rat
Ryota Tokunaga, Rie Shimoju, Hideshi Shibata, Mieko Kurosaw. Somatosensory regulation of serotonin release in the central nucleus of the amygdala is mediated via corticotropin releasing factor and gamma-aminobutyric acid in the dorsal raphe nucleus. The journal of physiological sciences : JPS. vol 67. issue 6. 2018-07-02. PMID:27744641. somatosensory regulation of serotonin release in the central nucleus of the amygdala is mediated via corticotropin releasing factor and gamma-aminobutyric acid in the dorsal raphe nucleus. 2018-07-02 2023-08-13 rat
Nerea Llamosas, Luisa Ugedo, Maria Torrecill. Inactivation of GIRK channels weakens the pre- and postsynaptic inhibitory activity in dorsal raphe neurons. Physiological reports. vol 5. issue 3. 2018-06-22. PMID:28196855. the serotonergic tone of the dorsal raphe (dr) is regulated by 5-ht 2018-06-22 2023-08-13 Not clear
Daniel G Ehlinger, Kathryn G Common. Altered Cav1.2 function in the Timothy syndrome mouse model produces ascending serotonergic abnormalities. The European journal of neuroscience. vol 46. issue 8. 2018-05-23. PMID:28921675. these regionally specific alterations are accompanied by an enhanced active coping response during acute stress (forced swim), serotonin neuron fos activity in the caudal dorsal raphe, and serotonin type 1a receptor-dependent feedback inhibition of the rostral dorsal raphe nuclei. 2018-05-23 2023-08-13 mouse
Daniel G Ehlinger, Kathryn G Common. Altered Cav1.2 function in the Timothy syndrome mouse model produces ascending serotonergic abnormalities. The European journal of neuroscience. vol 46. issue 8. 2018-05-23. PMID:28921675. collectively, these results suggest that the global gain-of-function cav1.2 mutation associated with timothy syndrome has pleiotropic effects on the ascending serotonin system including neuroanatomical changes, regional differences in forebrain serotonin metabolism and feedback regulatory control mechanisms within the dorsal raphe. 2018-05-23 2023-08-13 mouse
Eric W Prouty, Daniel J Chandler, Barry D Waterhous. Neurochemical differences between target-specific populations of rat dorsal raphe projection neurons. Brain research. vol 1675. 2018-05-22. PMID:28867482. serotonin (5-ht)-containing neurons in the dorsal raphe (dr) nucleus project throughout the forebrain and are implicated in many physiological processes and neuropsychiatric disorders. 2018-05-22 2023-08-13 rat
Christopher L Petersen, Laura M Hurle. Putting it in Context: Linking Auditory Processing with Social Behavior Circuits in the Vertebrate Brain. Integrative and comparative biology. vol 57. issue 4. 2018-05-04. PMID:28985384. we propose a model in which the brain's social behavior network serves as an afferent effector of the serotonergic dorsal raphe nucleus in order to gate contextual release of serotonin in the ic. 2018-05-04 2023-08-13 mouse
Christopher L Petersen, Laura M Hurle. Putting it in Context: Linking Auditory Processing with Social Behavior Circuits in the Vertebrate Brain. Integrative and comparative biology. vol 57. issue 4. 2018-05-04. PMID:28985384. specifically, discrete vasopressinergic nuclei within the hypothalamus and extended amygdala that project to the dorsal raphe are functionally engaged during contexts in which serotonin fluctuates in the ic. 2018-05-04 2023-08-13 mouse
Grazyna Rajkowska, Gouri Mahajan, Beata Legutko, Lavanya Challagundla, Michael Griswold, Paul R Albert, Mireille Daigle, Jose J Miguel-Hidalgo, Mark C Austin, Randy D Blakely, David C Steffens, Craig A Stockmeie. Length of axons expressing the serotonin transporter in orbitofrontal cortex is lower with age in depression. Neuroscience. vol 359. 2018-04-30. PMID:28711621. studies of major depressive disorder (mdd) in postmortem brain tissue report enhanced binding to inhibitory serotonin-1a autoreceptors in midbrain dorsal raphe and reductions in length of axons expressing the serotonin transporter (sert) in dorsolateral prefrontal cortex. 2018-04-30 2023-08-13 human
Joseph I Terranova, Zhimin Song, Tony E Larkin, Nathan Hardcastle, Alisa Norvelle, Ansa Riaz, H Elliott Alber. Serotonin and arginine-vasopressin mediate sex differences in the regulation of dominance and aggression by the social brain. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 46. 2018-04-27. PMID:27807133. acquisition of dominance was associated with activation of 5-ht neurons within the dorsal raphe in females and activation of hypothalamic avp neurons in males. 2018-04-27 2023-08-13 Not clear
Eran Lottem, Dhruba Banerjee, Pietro Vertechi, Dario Sarra, Matthijs Oude Lohuis, Zachary F Maine. Activation of serotonin neurons promotes active persistence in a probabilistic foraging task. Nature communications. vol 9. issue 1. 2018-04-27. PMID:29520000. we show that optogenetic activation of 5-ht neurons in the dorsal raphe nucleus increases the willingness of mice to actively attempt to exploit a reward site before giving up. 2018-04-27 2023-08-13 mouse
Emi Hasegawa, Takashi Maejima, Takayuki Yoshida, Olivia A Masseck, Stefan Herlitze, Mitsuhiro Yoshioka, Takeshi Sakurai, Michihiro Mied. Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 17. 2018-04-23. PMID:28396432. serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity. 2018-04-23 2023-08-13 mouse
Emi Hasegawa, Takashi Maejima, Takayuki Yoshida, Olivia A Masseck, Stefan Herlitze, Mitsuhiro Yoshioka, Takeshi Sakurai, Michihiro Mied. Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 17. 2018-04-23. PMID:28396432. in a mouse model for narcolepsy, we previously demonstrated that serotonin neurons of the dorsal raphe nucleus (drn) mediate the suppression of cataplexy-like episodes (cles) by orexin neurons. 2018-04-23 2023-08-13 mouse