| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea Godino, Soledad Pitra, Hugo F Carrer, Laura Viva. Body sodium overload modulates the firing rate and fos immunoreactivity of serotonergic cells of dorsal raphe nucleus. PloS one. vol 8. issue 9. 2014-05-27. PMID:24073217. |
in order to determine whether serotonergic (5ht) dorsal raphe nucleus (drn) cells are involved in body sodium status regulation, the effect of a s.c. infusion of either 2 m or 0.15 m nacl on 5ht drn neuron firing was studied using single unit extracellular recordings. |
2014-05-27 |
2023-08-12 |
rat |
| Benjamin D Rood, Lyngine H Calizo, David Piel, Zachary P Spangler, Kaitlin Campbell, Sheryl G Bec. Dorsal raphe serotonin neurons in mice: immature hyperexcitability transitions to adult state during first three postnatal weeks suggesting sensitive period for environmental perturbation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 14. 2014-05-22. PMID:24695701. |
dorsal raphe serotonin neurons in mice: immature hyperexcitability transitions to adult state during first three postnatal weeks suggesting sensitive period for environmental perturbation. |
2014-05-22 |
2023-08-13 |
mouse |
| Zhixiang Liu, Jingfeng Zhou, Yi Li, Fei Hu, Yao Lu, Ming Ma, Qiru Feng, Ju-En Zhang, Daqing Wang, Jiawei Zeng, Junhong Bao, Ji-Young Kim, Zhou-Feng Chen, Salah El Mestikawy, Minmin Lu. Dorsal raphe neurons signal reward through 5-HT and glutamate. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656254. |
dorsal raphe neurons signal reward through 5-ht and glutamate. |
2014-05-21 |
2023-08-12 |
mouse |
| Zhixiang Liu, Jingfeng Zhou, Yi Li, Fei Hu, Yao Lu, Ming Ma, Qiru Feng, Ju-En Zhang, Daqing Wang, Jiawei Zeng, Junhong Bao, Ji-Young Kim, Zhou-Feng Chen, Salah El Mestikawy, Minmin Lu. Dorsal raphe neurons signal reward through 5-HT and glutamate. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656254. |
the dorsal raphe nucleus (drn) in the midbrain is a key center for serotonin (5-hydroxytryptamine; 5-ht)-expressing neurons. |
2014-05-21 |
2023-08-12 |
mouse |
| Charles R Ashby, John H Kehne, Gerd D Bartoszyk, Matthew J Renda, Maria Athanasiou, Kerri A Pierz, Christoph A Seyfrie. Electrophysiological evidence for rapid 5-HT₁A autoreceptor inhibition by vilazodone, a 5-HT₁A receptor partial agonist and 5-HT reuptake inhibitor. European journal of pharmacology. vol 714. issue 1-3. 2014-05-06. PMID:23872377. |
this study examined the effect of vilazodone, a combined serotonin (5-ht) reuptake inhibitor and 5-ht(1a) receptor partial agonist, paroxetine and fluoxetine on the sensitivity of 5-ht(1a) autoreceptors of serotonergic dorsal raphe nucleus neurons in rats. |
2014-05-06 |
2023-08-12 |
rat |
| Sawako Tabuchi, Tomomi Tsunematsu, Thomas S Kilduff, Shouta Sugio, Ming Xu, Kenji F Tanaka, Satoru Takahashi, Makoto Tominaga, Akihiro Yamanak. Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness. Sleep. vol 36. issue 9. 2014-04-25. PMID:23997373. |
serotonergic (5ht) neurons of the dorsal raphe nuclei receive excitatory input from hypothalamic orexin (hypocretin) neurons and reciprocally inhibit orexin neurons through the 5ht1a receptor. |
2014-04-25 |
2023-08-12 |
Not clear |
| Erwan Le Maître, Nathalie Dourmap, Catherine Vilpoux, Romain Leborgne, François Janin, Jean-Jacques Bonnet, Jean Costentin, Isabelle Leroux-Nicolle. Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin. Brain research. vol 1520. 2014-04-11. PMID:23669068. |
acute and subchronic treatments with selective serotonin reuptake inhibitors increase nociceptin/orphanin fq (nop) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/nop system and serotonin. |
2014-04-11 |
2023-08-12 |
rat |
| Erwan Le Maître, Nathalie Dourmap, Catherine Vilpoux, Romain Leborgne, François Janin, Jean-Jacques Bonnet, Jean Costentin, Isabelle Leroux-Nicolle. Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin. Brain research. vol 1520. 2014-04-11. PMID:23669068. |
we have previously shown that nop receptors were located on serotonergic neurons in the rat dorsal raphe nucleus, suggesting possible direct interactions between nociceptin and serotonin in this region, which is a target for antidepressant action. |
2014-04-11 |
2023-08-12 |
rat |
| Erwan Le Maître, Nathalie Dourmap, Catherine Vilpoux, Romain Leborgne, François Janin, Jean-Jacques Bonnet, Jean Costentin, Isabelle Leroux-Nicolle. Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin. Brain research. vol 1520. 2014-04-11. PMID:23669068. |
using microdialysis experiments, we demonstrated that nop-receptor activation by infusion of nociceptin 10(-6) m or 10(-5) m increased the level of extracellular serotonin in the dorsal raphe nucleus. |
2014-04-11 |
2023-08-12 |
rat |
| Erwan Le Maître, Nathalie Dourmap, Catherine Vilpoux, Romain Leborgne, François Janin, Jean-Jacques Bonnet, Jean Costentin, Isabelle Leroux-Nicolle. Acute and subchronic treatments with selective serotonin reuptake inhibitors increase Nociceptin/Orphanin FQ (NOP) receptor density in the rat dorsal raphe nucleus; interactions between nociceptin/NOP system and serotonin. Brain research. vol 1520. 2014-04-11. PMID:23669068. |
these results confirm the existence of reciprocal interactions between serotonin and nociceptin/nop transmissions in the dorsal raphe nucleus. |
2014-04-11 |
2023-08-12 |
rat |
| Jennifer M Spaethling, David Piel, Hannah Dueck, Peter T Buckley, Jacqueline F Morris, Stephen A Fisher, Jaehee Lee, Jai-Yoon Sul, Junhyong Kim, Tamas Bartfai, Sheryl G Beck, James H Eberwin. Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 2. 2014-03-27. PMID:24192459. |
despite the recognized importance of the dorsal raphe (dr) serotonergic (5-ht) nuclei in the pathophysiology of depression and anxiety, the molecular components/putative drug targets expressed by these neurons are poorly characterized. |
2014-03-27 |
2023-08-12 |
Not clear |
| Collin Challis, Sheryl G Beck, Olivier Berto. Optogenetic modulation of descending prefrontocortical inputs to the dorsal raphe bidirectionally bias socioaffective choices after social defeat. Frontiers in behavioral neuroscience. vol 8. 2014-03-05. PMID:24596546. |
here we examined the organization and plasticity of microcircuits implicated in top-down control of 5-ht neurons in the dorsal raphe nucleus (drn) by excitatory inputs from the ventromedial prefrontal cortex (vmpfc) and their role in social approach-avoidance decisions. |
2014-03-05 |
2023-08-12 |
Not clear |
| Salvador Hernandez-Lopez, Julieta Garduño, Stefan Mihailesc. Nicotinic modulation of serotonergic activity in the dorsal raphe nucleus. Reviews in the neurosciences. vol 24. issue 5. 2014-02-20. PMID:24021594. |
the dorsal raphe nucleus (drn) contains the major amount of 5-ht neurons projecting to different parts of the brain. |
2014-02-20 |
2023-08-12 |
Not clear |
| James H Fox, Christopher A Lowr. Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior. Frontiers in neuroscience. vol 7. 2014-02-18. PMID:24065880. |
crf and crf-related peptides act within the dorsal raphe nucleus (dr), the major source for serotonin (5-ht) in the brain, to alter the neuronal activity of specific subsets of serotonergic neurons and to influence stress-related behavior. |
2014-02-18 |
2023-08-12 |
Not clear |
| Yukio Ago, Ryota Araki, Tatsunori Tanaka, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsud. Role of social encounter-induced activation of prefrontal serotonergic systems in the abnormal behaviors of isolation-reared mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 8. 2014-02-13. PMID:23426384. |
a 5-ht1a receptor agonist, a metabotropic glutamate 2/3 receptor agonist, and a gamma-aminobutyric acid a receptor agonist attenuated isolation-induced aggressive behaviors and encounter-induced hyperactivity, c-fos expression in the prefrontal cortex and dorsal raphe nucleus, and increases in prefrontal 5-ht levels. |
2014-02-13 |
2023-08-12 |
mouse |
| Lawrence S Own, Rimsha Iqbal, Paresh D Pate. Maternal separation alters serotonergic and HPA axis gene expression independent of separation duration in mice. Brain research. vol 1515. 2014-02-11. PMID:23548594. |
as adults, pups that experienced ms15 or ms180 demonstrated decreases in tryptophan hydroxylase 2 and serotonin transporter mrna in the dorsal raphe dorsalis and ventralis, and increases in glucocorticoid receptor mrna in the dentate gyrus of the hippocampus. |
2014-02-11 |
2023-08-12 |
mouse |
| Makiko Yamada, Yukie Kawahara, Fumi Kaneko, Yuki Kishikawa, Naoki Sotogaku, Wilfred J Poppinga, Joost H A Folgering, Eliyahu Dremencov, Hiroshi Kawahara, Akinori Nish. Upregulation of the dorsal raphe nucleus-prefrontal cortex serotonin system by chronic treatment with escitalopram in hyposerotonergic Wistar-Kyoto rats. Neuropharmacology. vol 72. 2014-02-11. PMID:23643754. |
dorsal raphe nucleus (drn) serotonin (5-ht) neurons projecting to the prefrontal cortex (pfc) comprise the important neurocircuitry underlying the pathophysiology of depression. |
2014-02-11 |
2023-08-12 |
rat |
| Chaoran Ren, Liju Luan, Benson Wui-Man Lau, Xin Huang, Jian Yang, Yuan Zhou, Xihong Wu, Jie Gao, Gary E Pickard, Kwok-Fai So, Mingliang P. Direct retino-raphe projection alters serotonergic tone and affective behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 7. 2014-01-24. PMID:23370156. |
we found that light deprivation produces a depressive-like behavioral state that is reversed by activation of direct retinal signals to the serotonergic dorsal raphe nucleus (drn) in a manner equivalent to treatment with the selective serotonin reuptake inhibitor fluoxetine. |
2014-01-24 |
2023-08-12 |
Not clear |
| G Quesseveur, C Repérant, D J David, A M Gardier, C Sanchez, B P Guiar. 5-HT₂A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system. Experimental brain research. vol 226. issue 2. 2014-01-06. PMID:23411676. |
the 5-ht2ar agonist doi decreased the firing rate of 5-ht neurons in the dorsal raphe (dr) nucleus of 5-ht2ar(+/+) anesthetized mice. |
2014-01-06 |
2023-08-12 |
mouse |
| Ryoko Hiroi, Robert J Hand. Estrogen receptor-β regulates human tryptophan hydroxylase-2 through an estrogen response element in the 5' untranslated region. Journal of neurochemistry. vol 127. issue 4. 2014-01-06. PMID:24033289. |
in the dorsal raphe nucleus, 17β-estradiol (e2) increases the expression of the brain-specific, rate-limiting enzyme for serotonin biosynthesis, tryptophan hydroxylase-2 (tph2). |
2014-01-06 |
2023-08-12 |
human |