| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephanie R Fox, Evan S Deneri. Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 23. 2012-08-09. PMID:22674259. |
engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus. |
2012-08-09 |
2023-08-12 |
mouse |
| Stephanie R Fox, Evan S Deneri. Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 23. 2012-08-09. PMID:22674259. |
here, we show that en1 and en2 are expressed in maturing 5-ht neurons that will form the dorsal raphe nucleus (drn) and part of the median raphe nucleus. |
2012-08-09 |
2023-08-12 |
mouse |
| Alok Joshi, KongFatt Wong-Lin, T Martin McGinnity, Girijesh Prasa. A mathematical model to explore the interdependence between the serotonin and orexin/hypocretin systems. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2011. 2012-08-08. PMID:22256017. |
the dorsal raphe nucleus (drn) and the lateral hypothalamus area (lha) are brain regions that are sources of 5-ht and ox, and there is evidence that suggests a reciprocal interaction between them. |
2012-08-08 |
2023-08-12 |
Not clear |
| Pierre-Eric Lutz, Amynah A Pradhan, Celia Goeldner, Brigitte L Kieffe. Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 11. 2012-08-01. PMID:21402471. |
using [(35)s]gtpγs autoradiography in mice, we show that 5-ht(1a) receptor function is enhanced by chronic morphine treatment in the medial prefrontal cortex, and decreased in dorsal raphe nucleus one week later, two regions involved in emotional processing. |
2012-08-01 |
2023-08-12 |
mouse |
| Sayamwong E Hammack, Matthew A Cooper, Kimberly R Leza. Overlapping neurobiology of learned helplessness and conditioned defeat: implications for PTSD and mood disorders. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:21396383. |
investigations into the neural substrates that control lh and conditioned defeat revealed that increased 5-ht activity in the dorsal raphe nucleus (drn) is critical for both models. |
2012-07-27 |
2023-08-12 |
rat |
| E M Rock, D Bolognini, C L Limebeer, M G Cascio, S Anavi-Goffer, P J Fletcher, R Mechoulam, R G Pertwee, L A Parke. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21827451. |
cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-ht(1a) somatodendritic autoreceptors in the dorsal raphe nucleus. |
2012-07-27 |
2023-08-12 |
Not clear |
| E M Rock, D Bolognini, C L Limebeer, M G Cascio, S Anavi-Goffer, P J Fletcher, R Mechoulam, R G Pertwee, L A Parke. Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British journal of pharmacology. vol 165. issue 8. 2012-07-27. PMID:21827451. |
to evaluate the hypothesis that activation of somatodendritic 5-ht(1a) autoreceptors in the dorsal raphe nucleus (drn) produces the anti-emetic/anti-nausea effects of cannabidiol (cbd), a primary non-psychoactive cannabinoid found in cannabis. |
2012-07-27 |
2023-08-12 |
Not clear |
| Caroline E McCardle, Sarah E Gartsid. Effects of general anaesthetics on 5-HT neuronal activity in the dorsal raphe nucleus. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22197516. |
effects of general anaesthetics on 5-ht neuronal activity in the dorsal raphe nucleus. |
2012-07-27 |
2023-08-12 |
human |
| Caroline E McCardle, Sarah E Gartsid. Effects of general anaesthetics on 5-HT neuronal activity in the dorsal raphe nucleus. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22197516. |
here we used in vitro electrophysiology in dorsal raphe slices, to determine the effects of anaesthetically relevant concentrations of chloral hydrate (100 μm and 1 mm), urethane (10 and 30 mm), pentobarbitone (10 and 100 μm) and ketamine (10, 100 and 300 μm) on regulators of 5-ht firing activity. |
2012-07-27 |
2023-08-12 |
human |
| Mateus Dalbem Ferreira, Leda Menescal-de-Oliveir. Opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus modulates tonic immobility in guinea pigs. Physiology & behavior. vol 106. issue 2. 2012-07-27. PMID:22266678. |
our previous studies demonstrated that the stimulation of serotonin receptors in the dorsal raphe nucleus (drn) appears to be biphasic during ti responses in guinea pigs (cavia porcellus). |
2012-07-27 |
2023-08-12 |
Not clear |
| Molly L Rovin, Katherine A Boss-Williams, Reid S Alisch, James C Ritchie, David Weinshenker, Charles H K West, Jay M Weis. Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain. Neuropeptides. vol 46. issue 2. 2012-07-17. PMID:22317959. |
the present study examined the influence of chronic administration (for 14days, via subcutaneously-implanted minipump) of antidepressant (ad) drugs representing three different classes (tricyclic [desipramine], selective serotonin reuptake inhibitor [ssri] [paroxetine], and monoamine oxidase inhibitor [maoi] [phenelzine]) on mrna for gal, gal receptors (galr1, galr2, and galr3), and tyrosine hydroxylase (th), the rate-limiting enzyme for ne synthesis, in four brain regions--lc, a1/c1, dorsal raphe (drn), and ventral tegmentum (vta) of rats. |
2012-07-17 |
2023-08-12 |
rat |
| Shunske Tanahashi, Satoshi Yamamura, Masanori Nakagawa, Eishi Motomura, Motohiro Okad. Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus. Psychopharmacology. vol 220. issue 3. 2012-07-11. PMID:21947356. |
to clarify the mechanisms of action of lamotrigine (ltg) and carbamazepine (cbz), we determined their effects on serotonin release associated with crf in rat dorsal raphe nucleus (drn) and median prefrontal cortex (mpfc) using dual-probe microdialysis. |
2012-07-11 |
2023-08-12 |
rat |
| Lindsey MacGillivray, Katelyn B Reynolds, Patricia I Rosebush, Michael F Mazure. The comparative effects of environmental enrichment with exercise and serotonin transporter blockade on serotonergic neurons in the dorsal raphe nucleus. Synapse (New York, N.Y.). vol 66. issue 5. 2012-07-09. PMID:22121041. |
the comparative effects of environmental enrichment with exercise and serotonin transporter blockade on serotonergic neurons in the dorsal raphe nucleus. |
2012-07-09 |
2023-08-12 |
rat |
| Lindsey MacGillivray, Katelyn B Reynolds, Patricia I Rosebush, Michael F Mazure. The comparative effects of environmental enrichment with exercise and serotonin transporter blockade on serotonergic neurons in the dorsal raphe nucleus. Synapse (New York, N.Y.). vol 66. issue 5. 2012-07-09. PMID:22121041. |
we have previously reported that inhibition of the serotonin transporter (sert) by selective serotonin reuptake inhibitor (ssri) fluoxetine significantly reduces the number of tryptophan hydroxylase (tph)-positive cells in the dorsal raphe nucleus (drn). |
2012-07-09 |
2023-08-12 |
rat |
| Alexander K Converse, Yves Aubert, Mohammed Farhoud, Jamey P Weichert, Ian J Rowland, Nicole M Ingrisano, Kelly A Allers, Bernd Sommer, David H Abbot. Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets. NeuroImage. vol 60. issue 1. 2012-07-03. PMID:22233732. |
we hypothesized that chronic treatment with the 5-ht(1a) agonist 8-oh-dpat would alter the glucose metabolism index in dorsal raphe (dr), medial prefrontal cortex (mpfc), medial preoptic area of hypothalamus (mpoa), ventromedial nucleus of hypothalamus (vmh), and field ca1 of hippocampus. |
2012-07-03 |
2023-08-12 |
human |
| Natsuko Kubota, Seiichiro Amemiya, Chiharu Motoki, Tomomi Otsuka, Takeshi Nishijima, Ichiro Kit. Corticotropin-releasing factor antagonist reduces activation of noradrenalin and serotonin neurons in the locus coeruleus and dorsal raphe in the arousal response accompanied by yawning behavior in rats. Neuroscience research. vol 72. issue 4. 2012-06-25. PMID:22285921. |
corticotropin-releasing factor antagonist reduces activation of noradrenalin and serotonin neurons in the locus coeruleus and dorsal raphe in the arousal response accompanied by yawning behavior in rats. |
2012-06-25 |
2023-08-12 |
rat |
| Cécile Bétry, Adeline Etiévant, Laura Lambás-Señas, Andrew C McCreary, Nasser Haddjer. In vivo effects of pardoprunox (SLV308), a partial D₂/D₃ receptor and 5-HT1A receptor agonist, on rat dopamine and serotonin neuronal activity. Synapse (New York, N.Y.). vol 65. issue 10. 2012-05-30. PMID:21446003. |
we used in vivo electrophysiological paradigm in the rat to assess the effects of pardoprunox on da neuronal activity in ventral tegmental area (vta) and substantia nigra pars compacta (snc) as well as on 5-ht neuronal activity in dorsal raphe nucleus (drn). |
2012-05-30 |
2023-08-12 |
rat |
| Hidehiko Takahashi, Harumasa Takano, Colin F Camerer, Takashi Ideno, Shigetaka Okubo, Hiroshi Matsui, Yuki Tamari, Kazuhisa Takemura, Ryosuke Arakawa, Fumitoshi Kodaka, Makiko Yamada, Yoko Eguchi, Toshiya Murai, Yoshiro Okubo, Motoichiro Kato, Hiroshi Ito, Tetsuya Suhar. Honesty mediates the relationship between serotonin and reaction to unfairness. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 11. 2012-05-08. PMID:22371595. |
furthermore, individuals with a low level of serotonin transporters in the dorsal raphe nucleus (drn) are honest and trustful, and thus cannot tolerate unfairness, being candid in expressing their frustrations. |
2012-05-08 |
2023-08-12 |
human |
| Quentin Rainer, Hai T Nguyen, Gaël Quesseveur, Alain M Gardier, Denis J David, Bruno P Guiar. Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration. Molecular pharmacology. vol 81. issue 2. 2012-05-04. PMID:22031471. |
an increase in somatodendritic 5-ht(1a) autoreceptor density in the dorsal raphe (dr) attenuates the therapeutic activity of selective serotonin-reuptake inhibitors (ssris), whereas their functional desensitization promotes activation of brain serotonergic transmission, thereby representing an adaptive change relevant to their therapeutic effect. |
2012-05-04 |
2023-08-12 |
mouse |
| Paul R Matthews, Paul J Harriso. A morphometric, immunohistochemical, and in situ hybridization study of the dorsal raphe nucleus in major depression, bipolar disorder, schizophrenia, and suicide. Journal of affective disorders. vol 137. issue 1-3. 2012-04-27. PMID:22129767. |
however, it is unclear whether these conditions include morphological involvement of the dorsal raphe nucleus (drn), the origin of most forebrain 5-ht innervation. |
2012-04-27 |
2023-08-12 |
Not clear |