All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
Jean-Philippe Guilloux, Denis J P David, Lin Xia, Hai Thanh Nguyen, Quentin Rainer, Bruno P Guiard, Christelle Repérant, Thierry Deltheil, Miklos Toth, René Hen, Alain M Gardie. Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments. Neuropharmacology. vol 61. issue 3. 2011-10-14. PMID:21333660. deletion of both receptors resulted in (i) higher emotionality of animals, as observed in three unconditioned paradigms of anxiety (open field, elevated plus maze and novelty suppressed feeding tests); (ii) a ≈200% increase in the mean spontaneous firing rate of 5-ht neurons in the dorsal raphe nucleus (drn) compared to 5-ht(1a/1b)+/+ mice; (iii) elevated basal dialysate levels of 5-ht in the drn and frontal cortex; (iv) an exaggerated response to acute paroxetine administration in microdialysis experiments, and (v) increased basal core body temperature. 2011-10-14 2023-08-12 mouse
Samir Haj-Dahmane, Roh-Yu She. Modulation of the serotonin system by endocannabinoid signaling. Neuropharmacology. vol 61. issue 3. 2011-10-14. PMID:21354188. in this article, we review the role of ecb signaling in the regulation of the serotoninergic system with special emphasis on the cellular mechanisms by which cannabinoid cb(1) receptors modulate the excitability of dorsal raphe serotonin neurons. 2011-10-14 2023-08-12 Not clear
Lyngine H Calizo, Adaure Akanwa, Xiaohang Ma, Yu-Zhen Pan, Julia C Lemos, Caryne Craige, Lydia A Heemstra, Sheryl G Bec. Raphe serotonin neurons are not homogenous: electrophysiological, morphological and neurochemical evidence. Neuropharmacology. vol 61. issue 3. 2011-10-14. PMID:21530552. the median (mr) and dorsal raphe (dr) nuclei contain the majority of the 5-hydroxytryptamine (5-ht, serotonin) neurons that project to limbic forebrain regions, are important in regulating homeostatic functions and are implicated in the etiology and treatment of mood disorders and schizophrenia. 2011-10-14 2023-08-12 Not clear
Parastoo Hashemi, Elyse C Dankoski, Kevin M Wood, Rebecca Ellen Ambrose, Robert Mark Wightma. In vivo electrochemical evidence for simultaneous 5-HT and histamine release in the rat substantia nigra pars reticulata following medial forebrain bundle stimulation. Journal of neurochemistry. vol 118. issue 5. 2011-10-14. PMID:21682723. recently, we optimized fast-scan cyclic voltammetry for measuring 5-ht release and uptake in vivo in the substantia nigra pars reticulata (snr) with electrical stimulation of the dorsal raphe nucleus (drn) in the rat brain. 2011-10-14 2023-08-12 rat
Angela C Robert. The importance of serotonin for orbitofrontal function. Biological psychiatry. vol 69. issue 12. 2011-09-29. PMID:21353665. the orbitofrontal cortex (ofc) receives a dense serotonin (5-hydroxytryptamine, or 5-ht) innervation from the dorsal raphe nucleus, with a smaller contribution from the median raphe nucleus. 2011-09-29 2023-08-12 Not clear
Angela C Robert. The importance of serotonin for orbitofrontal function. Biological psychiatry. vol 69. issue 12. 2011-09-29. PMID:21353665. the failure of these same animals to explore alternative stimuli during extinction, along with the recent electrophysiological evidence that dorsal raphe nucleus neurons encode future motivational outcomes, implicates orbitofrontal 5-ht in the process by which animals either exploit current resources or explore alternative resources based on current reward expectations. 2011-09-29 2023-08-12 Not clear
Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. shifting topographic activation and 5-ht1a receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. 2011-09-26 2023-08-12 Not clear
Robin Sperling, Kathryn G Common. Shifting topographic activation and 5-HT1A receptor-mediated inhibition of dorsal raphe serotonin neurons produced by nicotine exposure and withdrawal. The European journal of neuroscience. vol 33. issue 10. 2011-09-26. PMID:21501256. to determine whether there are different subgroups of 5-ht cells activated during nicotine administration and withdrawal, we mapped the appearance of fos, a marker of neuronal activation, in 5-ht cells of the dorsal raphe nucleus (dr) and median raphe nucleus (mr). 2011-09-26 2023-08-12 Not clear
G A Grigor'ia. [Serotonin and impulsivity (experiments on animals)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 61. issue 3. 2011-09-12. PMID:21861382. the results of influence of antagonists and agonists of the different types and subtypes of 5-ht receptors (1a, b; 2a, b, c; 7) and the effects of the dorsal raphe nuclei lesions on characteristics of impulsivity related with a motor control, mechanisms of attention, reinforcement and decision making were summarized. 2011-09-12 2023-08-12 Not clear
Daniel D Lam, Gina M Leinninger, Gwendolyn W Louis, Alastair S Garfield, Oliver J Marston, Rebecca L Leshan, Erica L Scheller, Lyndsay Christensen, Jose Donato, Jing Xia, Mark L Evans, Carol Elias, Jeffrey W Dalley, Denis I Burdakov, Martin G Myers, Lora K Heisle. Leptin does not directly affect CNS serotonin neurons to influence appetite. Cell metabolism. vol 13. issue 5. 2011-09-05. PMID:21531340. although some leptin receptor (leprb) neurons lie close to 5-ht neurons in the dorsal raphe (dr), 5-ht neurons do not express leprb. 2011-09-05 2023-08-12 mouse
Bruno P Guiard, Franck Chenu, Mostafa El Mansari, Pierre Blie. Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons. The international journal of neuropsychopharmacology. vol 14. issue 2. 2011-09-02. PMID:20149268. the present in-vivo electrophysiological study was undertaken to determine the effects of the triple reuptake inhibitors sep-225289 and dov216303 on the neuronal activities of locus coeruleus (lc) ne, ventral tegmental area (vta) da and dorsal raphe (dr) 5-ht neurons. 2011-09-02 2023-08-12 Not clear
N Calvo, M Cecchi, M Kabbaj, S J Watson, H Aki. Differential effects of social defeat in rats with high and low locomotor response to novelty. Neuroscience. vol 183. 2011-08-26. PMID:21453756. analyses of in situ hybridization results found hr-lr differences in 5-ht(2a) mrna levels in the parietal cortex and 5-ht(1a) mrna levels in the dorsal raphe. 2011-08-26 2023-08-12 rat
I Ioakimidis, M Zandian, F Ulbl, C Bergh, M Leon, P Söderste. How eating affects mood. Physiology & behavior. vol 103. issue 3-4. 2011-08-24. PMID:21315752. when food is in short supply, the rhythm of the neural network for eating, including orbitofrontal cortex and brainstem, slows down and we suggest that this type of neural activity activates a partially overlapping neural network for mood, including dorsal raphe serotonin projections to the orbitofrontal and prefrontal cortex. 2011-08-24 2023-08-12 Not clear
Harumasa Takano, Hiroshi Ito, Hidehiko Takahashi, Ryosuke Arakawa, Masaki Okumura, Fumitoshi Kodaka, Tatsui Otsuka, Motoichiro Kato, Tetsuya Suhar. Serotonergic neurotransmission in the living human brain: a positron emission tomography study using [¹¹C]dasb and [¹¹C]WAY100635 in young healthy men. Synapse (New York, N.Y.). vol 65. issue 7. 2011-08-16. PMID:21484882. in contrast, the highest binding to 5-ht(1a) receptors was seen in the hippocampal regions, insula, neocortical regions, and dorsal raphe nucleus, and very low binding was found in the thalamus and basal ganglia. 2011-08-16 2023-08-12 human
Jin-Hee Seo, Yun-Hee Sung, Ki-Jeong Kim, Mal-Soon Shin, Eun-Kyu Lee, Chang-Ju Ki. Effects of Phellinus linteus administration on serotonin synthesis in the brain and expression of monocarboxylate transporters in the muscle during exhaustive exercise in rats. Journal of nutritional science and vitaminology. vol 57. issue 1. 2011-08-15. PMID:21512297. treatment with 200 mg/kg of pl led to a significant increase in the time to exhaustion in response to running on a treadmill and a significant decrease in 5-hydroxytryptamine synthesis and tryptophan hydroxylase expression in the dorsal raphe of rats. 2011-08-15 2023-08-12 rat
Antonio Ortega-Alvaro, Auxiliadora Aracil-Fernández, María S García-Gutiérrez, Francisco Navarrete, Jorge Manzanare. Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 7. 2011-08-10. PMID:21430651. cb(2)ko mice presented increased d(2)r and α(2c)r gene expressions in the prefrontal cortex (pfc) and locus coeruleus (lc), decreased 5-ht(2c)r gene expression in the dorsal raphe (dr), and 5-ht(2a)r gene expression in the pfc. 2011-08-10 2023-08-12 mouse
Ross A McDevitt, Ryoko Hiroi, Scott M Mackenzie, Nicholas C Robin, Aaron Cohn, Jeansok J Kim, John F Neumaie. Serotonin 1B autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior. Biological psychiatry. vol 69. issue 8. 2011-08-08. PMID:21353664. serotonin 1b autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior. 2011-08-08 2023-08-12 rat
Ross A McDevitt, Ryoko Hiroi, Scott M Mackenzie, Nicholas C Robin, Aaron Cohn, Jeansok J Kim, John F Neumaie. Serotonin 1B autoreceptors originating in the caudal dorsal raphe nucleus reduce expression of fear and depression-like behavior. Biological psychiatry. vol 69. issue 8. 2011-08-08. PMID:21353664. serotonin 1b (5-ht(1b)) autoreceptors regulate release of serotonin from terminals of dorsal raphe nucleus (drn) projections. 2011-08-08 2023-08-12 rat
Hideki Miura, Yu Ando, Yukihiro Noda, Kenichi Isobe, Norio Ozak. Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice. Stress (Amsterdam, Netherlands). vol 14. issue 3. 2011-08-05. PMID:21294659. behavior on an elevated plus-maze, and trp, kyn, and 5-ht levels in the prefrontal cortex, hippocampus, amygdala, and dorsal raphe nuclei were measured 1 and 4 weeks after stress exposure. 2011-08-05 2023-08-12 mouse
Hideki Miura, Yu Ando, Yukihiro Noda, Kenichi Isobe, Norio Ozak. Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice. Stress (Amsterdam, Netherlands). vol 14. issue 3. 2011-08-05. PMID:21294659. predator stress increased kyn levels in the prefrontal cortex (until 4 weeks after stress exposure) and dorsal raphe nuclei (for 1 week after stress exposure), decreased 5-ht levels in all brain regions (until 4 weeks after stress exposure). 2011-08-05 2023-08-12 mouse