All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
Christopher J O'Connell, Evan L Reeder, Sean M Collins, Kainat Lungani, Sophia V Norman, Matthew J Robso. Mild traumatic brain injury elicits time- and region-specific reductions in serotonin transporter protein expression and uptake capacity. Neuroreport. vol 33. issue 14. 2022-09-05. PMID:36062511. mtbi was found to decrease (≈26%) the protein levels of sert 3 days postinjury (dpi) in the dorsal raphe nucleus (drn), the primary locale of 5-ht neuronal cell bodies within the central nervous system. 2022-09-05 2023-08-14 Not clear
Daniil Grinchii, Marius C Hoener, Talah Khoury, Roman Dekhtiarenko, Reyhaneh Nejati Bervanlou, Daniela Jezova, Eliyahu Dremenco. Effects of acute and chronic administration of trace amine-associated receptor 1 (TAAR1) ligands on in vivo excitability of central monoamine-secreting neurons in rats. Molecular psychiatry. 2022-08-31. PMID:36045279. acute ro5256390 suppressed, and ro5263397 stimulated serotonin (5-ht) neurons of the dorsal raphe nucleus (drn) and dopamine neurons of the ventral tegmental area (vta) in brain slices, suggesting that the behavioral effects of taar1 ligands involve 5-ht and dopamine. 2022-08-31 2023-08-14 rat
Jalal Baruni, Liqun Lu. Illuminating complexity in serotonin neurons of the dorsal raphe nucleus. Neuron. vol 110. issue 16. 2022-08-18. PMID:35981523. illuminating complexity in serotonin neurons of the dorsal raphe nucleus. 2022-08-18 2023-08-14 Not clear
Jalal Baruni, Liqun Lu. Illuminating complexity in serotonin neurons of the dorsal raphe nucleus. Neuron. vol 110. issue 16. 2022-08-18. PMID:35981523. (2022) employ microendoscopy to record over 2,000 dorsal raphe serotonin neurons, yielding new insights into their activity from the single neuron to the population level. 2022-08-18 2023-08-14 Not clear
Tomonobu Kato, Yasue Mitsukura, Keitaro Yoshida, Masaru Mimura, Norio Takata, Kenji F Tanak. Oscillatory population-level activity of dorsal raphe serotonergic neurons is inscribed in sleep structure. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-08-15. PMID:35970565. dorsal raphe (dr) 5-ht neurons regulate sleep-wake transitions. 2022-08-15 2023-08-14 mouse
Remi Janet, Romain Ligneul, Annabel B Losecaat-Vermeer, Remi Philippe, Gabriele Bellucci, Edmund Derrington, Soyoung Q Park, Jean-Claude Drehe. Regulation of social hierarchy learning by serotonin transporter availability. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-08-09. PMID:35945275. learning social ranks was modulated by the dorsal raphe nucleus (drn) 5-ht function. 2022-08-09 2023-08-14 Not clear
Kanza M Khan, Gabrielle Bierlein-De La Rosa, Natalie Biggerstaff, Govindhasamy Pushpavathi Selvakumar, Ruixiang Wang, Suzanne Mason, Michael E Dailey, Catherine A Marcinkiewc. Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood. Brain, behavior, and immunity. 2022-07-30. PMID:35907582. here we report that mice exposed to adolescent intermittent access to ethanol (aie) exhibit increased pain sensitivity and depressive-like behaviors that persist for several weeks after alcohol cessation and are accompanied by elevated cd68 expression in microglia and reduced numbers of serotonin (5-ht)-expressing neurons in the dorsal raphe nucleus (drn). 2022-07-30 2023-08-14 mouse
Catharina S Hamann, Julian Bankmann, Hanna Mora Maza, Johannes Kornhuber, Iulia Zoicas, Angelika Schmitt-Böhre. Social Fear Affects Limbic System Neuronal Activity and Gene Expression. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897794. sfc+ mice also showed alterations in the expression of npy and serotonin system-related genes in the paraventricular nucleus of the hypothalamus, basolateral amygdala, septum and dorsal raphe nucleus, but not in the dorsal hippocampus. 2022-07-28 2023-08-14 mouse
Keaton A Unroe, Jessica L Maltman, Elizabeth A Shupe, Sarah M Clinto. Disrupted serotonin system development via early life antidepressant exposure impairs maternal care and increases serotonin receptor expression in adult female offspring. Developmental psychobiology. vol 64. issue 6. 2022-06-24. PMID:35748633. for example, early-life exposure to selective 5-ht reuptake inhibitor (ssri) antidepressants disrupts dorsal raphe function and triggers aberrant adult behaviors such as increased passive stress coping and anhedonia. 2022-06-24 2023-08-14 rat
Jing Wang, Yingzi Wang, Xiaona Du, Hailin Zhan. Potassium Channel Conductance Is Involved in Phenylephrine-Induced Spontaneous Firing of Serotonergic Neurons in the Dorsal Raphe Nucleus. Frontiers in cellular neuroscience. vol 16. 2022-06-23. PMID:35734219. the serotonergic (5-ht) network from the dorsal raphe nucleus (drn) of the brain has been demonstrated to regulate cognition, emotion, and behaviors, including learning and the sleep-wake cycle. 2022-06-23 2023-08-14 Not clear
Liuchang Zhou, Dan Liu, Zedan Xie, Di Deng, Guoqi Shi, Jinlan Zhao, Shasha Bai, Lei Yang, Rong Zhang, Yafei Sh. Electrophysiological Characteristics of Dorsal Raphe Nucleus in Tail Suspension Test. Frontiers in behavioral neuroscience. vol 16. 2022-06-17. PMID:35711694. the dorsal raphe nucleus (drn) is a major source of serotonin in the central nervous system, which is closely related to depression-like behaviors and is modulated by local gabaergic interneurons. 2022-06-17 2023-08-14 Not clear
Grace E Paquelet, Kassandra Carrion, Clay O Lacefield, Pengcheng Zhou, René Hen, Bradley R Mille. Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors. Neuron. 2022-06-14. PMID:35700737. single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors. 2022-06-14 2023-08-14 Not clear
T N Patel, H O Caiola, O G Mallari, K L Blandino, A R Goldenthal, S M Dymecki, B D Roo. Social interactions increase activation of vasopressin-responsive neurons in the dorsal raphe. Neuroscience. 2022-06-02. PMID:35654294. to better understand the neural circuitry underlying social behavior, we focused on neural circuits involving vasopressin neurons of the bed nucleus of the stria terminalis (bnst) and serotonin neurons of the dorsal raphe (dr). 2022-06-02 2023-08-14 mouse
Christopher J O'Connell, Evan L Reeder, Roman A Caceres, Sean M Collins, Kyla Q Chilton, Gary A Gudelsky, Matthew J Robso. Closed Head Traumatic Brain Injury Drives Protracted Inflammation and Remodeling of Serotonergic Architecture in the Dorsal Raphe Nucleus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554019. we hypothesize that tbi drives the formation of aberrant behavioral states linked to neuropsychiatric disorders through alterations of normal, physiologic 5-ht signaling stemming from 5-ht neurons located within the dorsal raphe nucleus (drn). 2022-05-13 2023-08-13 mouse
Tara P Cominski, Victoria Stiritz, Kevin D Bec. The Effects of Mild Traumatic Brain Injury (mTBI) on Serotonergic Gene Expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554362. results show altered expression levels of tryptophan hydroxylase and serotonin transporter genes in both the medial raphe and dorsal raphe nuclei in mtbi rats compared to sham control rats. 2022-05-13 2023-08-13 human
Jorge Chávez, Viridiana Alcántara-Alonso, Cinthia García-Luna, Paulina Soberanes-Chávez, Dimitris Grammatopoulos, Patricia de Gortar. Hypothalamic TRH mediates anorectic effects of serotonin in rats. eNeuro. 2022-05-11. PMID:35545425. hypothalamic pvn neurons receive serotonergic inputs from dorsal raphe nucleus and express serotonin (5ht) receptors such as 5ht 2022-05-11 2023-08-13 rat
Zijian Lv, Yuting Zhang, Lizi Zhang, Wenjuan Hou, Miao Lin, Yufeng Xun, Huan Ma, Yin Li, Yitong Li, Fadao Tai, Zhixiong H. Involvement of DR→mPFC 5-HTergic neural projections in changes of social exploration behaviors caused by adult chronic social isolation in mice. Brain research bulletin. 2022-05-08. PMID:35526586. this study assessed whether five weeks of continuous si at adulthood could alter social behaviors and whether dorsal raphe nucleus (dr) to medial prefrontal cortex (mpfc) 5-ht neural projections were involved in this alteration in c57bl/6j adult male mice. 2022-05-08 2023-08-13 mouse
Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong X. A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice. Nature neuroscience. 2022-05-02. PMID:35501380. in this study, we found that da neurons in the mouse ventral tegmental area bidirectionally regulate the activity of 5-ht neurons in the dorsal raphe nucleus (drn), with weaker stimulation causing drd2-dependent inhibition and overeating, while stronger stimulation causing drd1-dependent activation and anorexia. 2022-05-02 2023-08-13 mouse
Yun Wang, Mixia Wang, Yuchuan Dai, Yilin Song, Yiding Wang, Botao Lu, Yinghui Li, Xinxia Ca. PtNPs/Short MWCNT-PEDOT: PSS-Modified Microelectrode Array to Detect Neuronal Firing Patterns in the Dorsal Raphe Nucleus and Hippocampus of Insomnia Rats. Micromachines. vol 13. issue 3. 2022-03-26. PMID:35334780. in order to explore the effect of 5-ht deficiency-induced insomnia on brain regions related to memory in rats, we designed and fabricated a microelectrode array that simultaneously detects the electrical activity of the dorsal raphe nucleus (drn) and hippocampus in normal, insomnia and recovery rats in vivo. 2022-03-26 2023-08-13 rat
Danilo De Gregorio, Antonio Inserra, Justine P Enns, Athanasios Markopoulos, Michael Pileggi, Youssef El Rahimy, Martha Lopez-Canul, Stefano Comai, Gabriella Gobb. Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-03-18. PMID:35301424. employing in vivo electrophysiology, microionthophoresis, behavioral paradigms and morphology assays, we assessed the impact of acute and chronic lsd administration on anxiety-like behavior, on the cortical dendritic spines and on the activity of serotonin (5-ht) neurons originating in the dorsal raphe nucleus (drn) in male mice exposed to chronic restraint stress. 2022-03-18 2023-08-13 mouse