All Relations between dorsal raphe and serotonin

Publication Sentence Publish Date Extraction Date Species
Anne Venner, Rebecca Y Broadhurst, Lauren T Sohn, William D Todd, Patrick M Fulle. Selective activation of serotoninergic dorsal raphe neurons facilitates sleep through anxiolysis. Sleep. vol 43. issue 2. 2021-04-14. PMID:31553451. here we sought to define the specific contribution of 5ht neurons within the dorsal raphe nucleus (drn5ht) to sleep and arousal control. 2021-04-14 2023-08-13 Not clear
Stephanie C Gantz, Khaled Moussawi, Holly S Hak. Delta glutamate receptor conductance drives excitation of mouse dorsal raphe neurons. eLife. vol 9. 2021-04-07. PMID:32234214. the dorsal raphe nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emotional behaviors. 2021-04-07 2023-08-13 mouse
Stephanie C Gantz, Khaled Moussawi, Holly S Hak. Delta glutamate receptor conductance drives excitation of mouse dorsal raphe neurons. eLife. vol 9. 2021-04-07. PMID:32234214. action potential firing of serotonin dorsal raphe neurons is driven via α1-adrenergic receptors (α1-a 2021-04-07 2023-08-13 mouse
Hicham Chatoui, Abdellatif Abbaoui, Omar El Hiba, Ahmed Draoui, Halima Gamran. Neurobehavioral and neurophysiological effects of prolonged osmotic stress in rats: A focus on anxiety state and pain perception. Journal of chemical neuroanatomy. vol 106. 2021-04-06. PMID:32334030. this study examined the effect of prolonged water deprivation, in rat, on 5-ht and th- immuno-expression in dorsal raphe nucleus (drn), substantia nigra pars compacta (snc), ventral tegmental area (vta), and magnus raphe nucleus (mrn). 2021-04-06 2023-08-13 rat
Tomoko Soga, Shingo Nakajima, Ishwar S Parha. Expression of Repressor Element 1 Silencing Transcription Factor (REST) in Serotonin Neurons in the Adult Male Nile Tilapia ( Frontiers in neuroanatomy. vol 14. 2021-03-30. PMID:33776659. expression of repressor element 1 silencing transcription factor (rest) in serotonin neurons in the adult male nile tilapia ( repressor element-1 silencing transcription factor (rest) is highly expressed in the dorsal raphe where serotonin (5-hydroxytryptamine, 5-ht) neurons are located. 2021-03-30 2023-08-13 Not clear
Rachel A Daut, J Russell Ravenel, Linda R Watkins, Steven F Maier, Laura K Fonke. The behavioral and neurochemical effects of an inescapable stressor are time of day dependent. Stress (Amsterdam, Netherlands). vol 23. issue 4. 2021-03-24. PMID:31868091. anxiety- and fear-related behavioral changes produced by is are driven by sensitization of serotonergic (5-hydroxytryptamine, 5-ht) neurons in the dorsal raphe nucleus (drn). 2021-03-24 2023-08-13 rat
Zohre Azimi, Ruxandra Barzan, Katharina Spoida, Tatjana Surdin, Patric Wollenweber, Melanie D Mark, Stefan Herlitze, Dirk Janck. Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input. eLife. vol 9. 2021-03-24. PMID:32252889. we combined optogenetic stimulation of the dorsal raphe nucleus (drn) with wide-field calcium imaging, extracellular recordings, and iontophoresis of serotonin (5-ht) receptor antagonists in the mouse visual cortex. 2021-03-24 2023-08-13 mouse
Chen Li, Nicholas McCloskey, Jared Phillips, Steven J Simmons, Lynn G Kirb. CRF-5-HT interactions in the dorsal raphe nucleus and motivation for stress-induced opioid reinstatement. Psychopharmacology. vol 238. issue 1. 2021-02-26. PMID:33231727. our previous data show that stressors can inhibit 5-ht neuronal activity and release by stimulating the release of the stress neurohormone corticotropin-releasing factor (crf) within the serotonergic dorsal raphe nucleus (drn). 2021-02-26 2023-08-13 Not clear
Zhuo Wang, Chen Li, Jiuyang Ding, Yanning Li, Zhihua Zhou, Yanjun Huang, Xiaohan Wang, Haoliang Fan, Jian Huang, Yitong He, Jianwei Li, Jun Chen, Pingming Qi. Basolateral Amygdala Serotonin 2C Receptor Regulates Emotional Disorder-Related Symptoms Induced by Chronic Methamphetamine Administration. Frontiers in pharmacology. vol 12. 2021-02-26. PMID:33628192. molecular and morphological evidence showed that chronic ma administration reduced the expression of the 5-hydroxytryptamine (5-ht) rate-limiting enzyme, tryptophan hydroxylase 2, in the dorsal raphe and the concentrations of 5-ht and its metabolite 5-hydroxyindoleacetic acid in the basolateral amygdala (bla) nuclei. 2021-02-26 2023-08-13 mouse
Lu-Lu Lin, Hong-Ping Li, Jing-Wen Yang, Xiao-Wan Hao, Shi-Yan Yan, Li-Qiong Wang, Fang-Ting Yu, Guang-Xia Shi, Cun-Zhi Li. Acupuncture for Psychological Disorders Caused by Chronic Pain: A Review and Future Directions. Frontiers in neuroscience. vol 14. 2021-02-16. PMID:33584181. in addition, 5-ht in the dorsal raphe nucleus, opioid receptors in the cingulate cortex, and plasma met-enkephalin are involved in acupuncture relief of pain and psychological symptoms. 2021-02-16 2023-08-13 human
Yuma Nagai, Kaito Takayama, Naoya Nishitani, Chihiro Andoh, Masashi Koda, Hisashi Shirakawa, Takayuki Nakagawa, Kazuki Nagayasu, Akihiro Yamanaka, Shuji Kanek. The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion. International journal of molecular sciences. vol 21. issue 6. 2021-01-13. PMID:32245184. the role of dorsal raphe serotonin neurons in the balance between reward and aversion. 2021-01-13 2023-08-13 Not clear
Yuma Nagai, Kaito Takayama, Naoya Nishitani, Chihiro Andoh, Masashi Koda, Hisashi Shirakawa, Takayuki Nakagawa, Kazuki Nagayasu, Akihiro Yamanaka, Shuji Kanek. The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion. International journal of molecular sciences. vol 21. issue 6. 2021-01-13. PMID:32245184. many studies have shown the importance of dorsal raphe nucleus (drn) serotonin (5-ht) neurons in this process, but the strongly correlative link between the activity of drn 5-ht neurons and rewarding/aversive potency is under debate. 2021-01-13 2023-08-13 Not clear
Charlène Faye, René Hen, Bruno P Guiard, Christine A Denny, Alain M Gardier, Indira Mendez-David, Denis J Davi. Rapid Anxiolytic Effects of RS67333, a Serotonin Type 4 Receptor Agonist, and Diazepam, a Benzodiazepine, Are Mediated by Projections From the Prefrontal Cortex to the Dorsal Raphe Nucleus. Biological psychiatry. vol 87. issue 6. 2021-01-06. PMID:31623825. rapid anxiolytic effects of rs67333, a serotonin type 4 receptor agonist, and diazepam, a benzodiazepine, are mediated by projections from the prefrontal cortex to the dorsal raphe nucleus. 2021-01-06 2023-08-13 Not clear
Nina C Donner, Sofia M Davies, Stephanie D Fitz, Drake M Kienzle, Anantha Shekhar, Christopher A Lowr. Crh receptor priming in the bed nucleus of the stria terminalis (BNST) induces tph2 gene expression in the dorsomedial dorsal raphe nucleus and chronic anxiety. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31415826. since the bnst projects heavily to the dorsal raphe nucleus (dr), the main source of brain serotonin, we here tested the hypothesis that such repeated, anxiety-inducing activation of crh receptors in the bnst alters the expression of serotonergic genes in the dr, including tph2, the gene encoding the rate-limiting enzyme for brain serotonin synthesis, and slc6a4, the gene encoding the serotonin transporter (sert). 2021-01-04 2023-08-13 rat
Sophia Khom, Sarah A Wolfe, Reesha R Patel, Dean Kirson, David M Hedges, Florence P Varodayan, Michal Bajo, Marisa Robert. Alcohol Dependence and Withdrawal Impair Serotonergic Regulation of GABA Transmission in the Rat Central Nucleus of the Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 36. 2021-01-01. PMID:32769108. the cea receives dense innervation from the dorsal raphe nucleus, the major source of 5-ht, and expresses 5-ht receptor subtypes (e.g., 5-ht2c and 5-ht1a) critically linked to alcohol use disorder. 2021-01-01 2023-08-13 rat
Tadashi Takada, Naoki Yoneda, Tetsushi Hirano, Kanoko Onaru, Youhei Mantani, Toshifumi Yokoyama, Hiroshi Kitagawa, Yoshiaki Tabuchi, Collins Nimako, Mayumi Ishizuka, Yoshinori Ikenaka, Nobuhiko Hosh. Combined exposure to dinotefuran and chronic mild stress counteracts the change of the emotional and monoaminergic neuronal activity induced by either exposure singly despite corticosterone elevation in mice. The Journal of veterinary medical science. vol 82. issue 3. 2020-11-16. PMID:31983702. in addition, serotonin (5-ht) and tryptophan hydroxylase 2 (tph2) of the dorsal raphe nuclei (drn) and median raphe nuclei (mrn) and tyrosine hydroxylase (th) of the ventral tegmental area and substantia nigra (sn) were evaluated immunohistochemically. 2020-11-16 2023-08-13 mouse
Renkai Ge, Yue Da. Three-Week Treadmill Exercise Enhances Persistent Inward Currents, Facilitates Dendritic Plasticity, and Upregulates the Excitability of Dorsal Raphe Serotonin Neurons in ePet-EYFP Mice. Frontiers in cellular neuroscience. vol 14. 2020-11-13. PMID:33177992. three-week treadmill exercise enhances persistent inward currents, facilitates dendritic plasticity, and upregulates the excitability of dorsal raphe serotonin neurons in epet-eyfp mice. 2020-11-13 2023-08-13 mouse
Kaitlin Farrell, John D Houl. Systemic Inhibition of Soluble Tumor Necrosis Factor with XPro1595 Exacerbates a Post-Spinal Cord Injury Depressive Phenotype in Female Rats. Journal of neurotrauma. vol 36. issue 21. 2020-11-10. PMID:31064292. the goal of this study was to elucidate the role of inflammatory cytokine tumor necrosis factor (tnf) in the dorsal raphe nucleus (drn, the principle source of serotonin to the brain) in the development and possible treatment of depression after sci. 2020-11-10 2023-08-13 rat
Lucia Caffino, Michel M M Verheij, Lin Que, Chao Guo, Judith R Homberg, Fabio Fumagall. Increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30144237. the dorsal raphe nucleus, where 5-ht neurons originate, and the hb are anatomically and reciprocally interconnected. 2020-10-28 2023-08-13 rat
Caio Henrique Mazucanti, Qing-Rong Liu, Doyle Lang, Nicholas Huang, Jennifer F O'Connell, Simonetta Camandola, Josephine M Ega. Release of insulin produced by the choroid plexis is regulated by serotonergic signaling. JCI insight. vol 4. issue 23. 2020-10-19. PMID:31647782. in vivo depletion of brain serotonin in the dorsal raphe nucleus negatively affected insulin expression in the chp, suggesting an endogenous modulation of chp insulin by serotonin. 2020-10-19 2023-08-13 mouse