| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
the present study demonstrated for the first time that acute as well as subchronic (4 days) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3 mg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the β-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-08-14 |
rat |
| Jannike M Andersen, Siri H Opdal, Christian P Müller, Fernando Boi. CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment. Behavioural brain research. vol 390. 2021-10-25. PMID:32407818. |
decreases in camkii thr286 phosphorylation were observed in dorsal striatum after the sub-chronic pharmacological treatment. |
2021-10-25 |
2023-08-13 |
mouse |
| Jannike M Andersen, Siri H Opdal, Christian P Müller, Fernando Boi. CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment. Behavioural brain research. vol 390. 2021-10-25. PMID:32407818. |
whereas an acute single administration of morphine or m6g caused increases in camkii levels and phosphorylation at thr286 and β-actin in striatal areas, cpp induced by these opioids was accompanied primarily by an increase in the protein levels of both camkii isoforms and β-actin in dorsal striatum and hippocampus. |
2021-10-25 |
2023-08-13 |
mouse |
| Dvijen C Purohit, Atulya D Mandyam, Michael J Terranova, Chitra D Mandya. Voluntary wheel running during adolescence distinctly alters running output in adulthood in male and female rats. Behavioural brain research. vol 377. 2021-04-23. PMID:31521739. |
notably, running during adolescence-induced higher exercise output in adult males was associated with hyperactivation of camkii in the dorsal striatum, indicating a mechanistic role for camkii in running output. |
2021-04-23 |
2023-08-13 |
rat |
| Dvijen C Purohit, Atulya D Mandyam, Michael J Terranova, Chitra D Mandya. Voluntary wheel running during adolescence distinctly alters running output in adulthood in male and female rats. Behavioural brain research. vol 377. 2021-04-23. PMID:31521739. |
higher running output in females was associated with reduced expression of tyrosine hydroxylase and hyperactivation of calcium/calmodulin-dependent protein kinase ii (camkii) in the dorsal striatum. |
2021-04-23 |
2023-08-13 |
rat |
| Johanna G Pasek, Xiaohan Wang, Roger J Colbra. Differential CaMKII regulation by voltage-gated calcium channels in the striatum. Molecular and cellular neurosciences. vol 68. 2016-07-11. PMID:26255006. |
to address this, mouse brain slices were treated with pharmacological modulators of calcium channels and punches of dorsal striatum were immunoblotted for camkii thr286 autophosphorylation as an index of camkii activation. |
2016-07-11 |
2023-08-13 |
mouse |
| Kyoung-Shim Kim, Hannah Kim, Sun-Kyu Park, Pyung-Lim Ha. The dorsal striatum expressing adenylyl cyclase-5 controls behavioral sensitivity of the righting reflex to high-dose ethanol. Brain research. vol 1489. 2013-05-01. PMID:23063718. |
consistently with these results, stereotaxic infusion of kn62 (camkii inhibitor), sirna-camkiiα, or sirna-bdnf, within the dorsal striatum was sufficient to prolong lorr. |
2013-05-01 |
2023-08-12 |
mouse |
| Norifumi Shioda, Yui Yamamoto, Masahiko Watanabe, Bert Binas, Yuji Owada, Kohji Fukunag. Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 8. 2010-05-04. PMID:20181611. |
furthermore, phosphorylation of camkii (ca(2+)/calmodulin-dependent protein kinase ii) and erk (extracellular signal-regulated kinase) was significantly increased in the dorsal striatum. |
2010-05-04 |
2023-08-12 |
mouse |
| Eun Sang Choe, John Q Wan. CaMKII regulates amphetamine-induced ERK1/2 phosphorylation in striatal neurons. Neuroreport. vol 13. issue 8. 2002-07-26. PMID:12060798. |
inhibition of camkii by intrastriatal infusion of kn62 (2, 10, or 25 nmol) attenuated amphetamine-induced increases in perk1/2, pcreb, and pelk-1 immunoreactivity in the ipsilateral dorsal striatum in a dose-dependent manner. |
2002-07-26 |
2023-08-12 |
Not clear |
| E S Choe, J Q Wan. Group I metabotropic glutamate receptors control phosphorylation of CREB, Elk-1 and ERK via a CaMKII-dependent pathway in rat striatum. Neuroscience letters. vol 313. issue 3. 2002-01-30. PMID:11682144. |
to evaluate putative roles of ca2+/calmodulin-dependent protein kinase ii (camkii) in creb, elk-1 and erk phosphorylation, the camkii inhibitor, kn62, was infused simultaneously with the group i mglur agonist, 3,5-dihydroxyphenylglycine (dhpg), into the rat dorsal striatum. |
2002-01-30 |
2023-08-12 |
rat |
| A G Sadil. Multiple evidence of a segmental defect in the anterior forebrain of an animal model of hyperactivity and attention deficit. Neuroscience and biobehavioral reviews. vol 24. issue 1. 2000-02-17. PMID:10654674. |
microcomputer-assisted high-resolution image analysis showed in the shr a higher density of da d-1 receptors and a lower density of d-3 autoreceptors paralleled by a reduced number of elements positive for camkii and tfs in a restricted segment of the anterior forebrain that included the most rostral portions of the caudate-putamen, pole and shell of the nucleus accumbens and olfactory tubercle. |
2000-02-17 |
2023-08-12 |
rat |