| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo-Han He, Ya-Hui Yang, Bo-Wen Hsiao, Wan-Ting Lin, Yi-Fang Chuang, Shih-Yun Chen, Fu-Chin Li. Foxp2 is Required for Nucleus Accumbens-mediated Multifaceted Limbic Function. Neuroscience. 2024-02-14. PMID:38354901. |
although foxp2 has been well studied in the dorsal striatum, its function in the nucleus accumbens (nac) of the ventral striatum remains elusive. |
2024-02-14 |
2024-02-17 |
mouse |
| Cameron J Davidson, John H Hannigan, Shane A Perrine, Scott E Bowe. Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. Neurotoxicology and teratology. 2024-01-10. PMID:38199311. |
analysis of monoamines and their metabolites using high pressure liquid chromatography (hplc) within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dstr), and ventral tegmental area (vta) revealed subtle effects on monoamine or metabolite levels following cumulative dosing that varied by drug (cocaine and ethanol) and abstinence duration. |
2024-01-10 |
2024-01-13 |
mouse |
| Yuki Moriya, Yoshiyuki Kasahara, Kana Ishihara, Frank Scott Hall, Yoko Hagino, René Hen, Kazutaka Ikeda, George R Uhl, Ichiro Sor. Heterozygous and homozygous gene knockout of the 5-HT1B receptor have different effects on methamphetamine-induced behavioral sensitization. Behavioural pharmacology. 2023-09-05. PMID:37668157. |
to clarify the action of meth in 5-ht1b ko mice the effects of meth on extracellular levels of da (daec) and 5-ht (5-htec) in the caudate putamen (cpu) and the nucleus accumbens (nac) were examined. |
2023-09-05 |
2023-09-07 |
mouse |
| Yuan-Yuan Han, Jian-Wen Zhou, Zhi-Wei Guo, Zhuo-Qing Wu, Zai-Yong Zhang, De-Xiang Liu, Cheng Lon. Multiple brain regions are involved in reaction to acute restraint stress in CYLD-knockout mice. Stress (Amsterdam, Netherlands). vol 26. issue 1. 2023-07-03. PMID:37395260. |
here we report that cyld deficiency leads to an unexpected reaction to ars in mice, and is accompanied by significant neuronal activation of brain regions including the medial prefrontal cortex (mpfc), dorsal striatum (ds), nucleus accumbens (nac), and basal lateral amygdala (bla), but not ventral hippocampus (vhpc). |
2023-07-03 |
2023-08-14 |
mouse |
| Hsiao-Ying Kuo, Ya-Hui Yang, Shih-Yun Chen, Tzu-Hsin Kuo, Wan-Ting Lin, Fu-Chin Li. Differential development of dendritic spines in striatal projection neurons of direct and indirect pathways in the caudoputamen and nucleus accumbens. eNeuro. 2023-05-30. PMID:37253589. |
here, we delineate the developmental trajectories of dendritic spines of dspns and ispns in the caudoputamen and nucleus accumbens (nac). |
2023-05-30 |
2023-08-14 |
mouse |
| C A Favoretto, N B Bertagna, T Righi, B T Rodolpho, A Anjos-Santos, F B R Silva, P C Bianchi, F C Cru. Impacts of maternal separation stress on ethanol-related responses, anxiety- and depressive-like behaviors in adolescent mice. Neuroscience letters. 2023-05-14. PMID:37182574. |
our results demonstrated that ms increased ethanol intake only in an acute manner and did not impact ethanol-induced fos expression in the dorsal striatum and nucleus accumbens (nac) core and shell subregions. |
2023-05-14 |
2023-08-14 |
mouse |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
the present study demonstrated for the first time that acute as well as subchronic (4 days) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3 mg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the β-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-08-14 |
rat |
| Qing Zhai, Ariful Islam, Bin Chen, Hengsen Zhang, Do Huu Chi, Md Al Mamun, Yutaka Takahashi, Noriko Sato, Hidenori Yamasue, Yoshiki Nakajima, Yu Nagashima, Fumito Sano, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Seto. Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. Cells. vol 12. issue 3. 2023-02-11. PMID:36766735. |
however, the detailed spatial distribution of 2-ag and its changes by crs in stress processing-related anatomical structures such as the anterior cingulate cortex (acc), caudate putamen (cp), nucleus accumbens (nac), and piriform cortex (pir) are still unclear. |
2023-02-11 |
2023-08-14 |
mouse |
| Anna L S Beeson, John Meitze. Estrous cycle impacts on dendritic spine plasticity in rat nucleus accumbens core and shell and caudate-putamen. The Journal of comparative neurology. 2023-02-09. PMID:36756791. |
considering the striatal brain regions, the nucleus accumbens (nac) core, nac shell, and caudate-putamen (cpu), the estrous cycle has previously been shown to impact relevant behaviors and disorders, neuromodulator action, and medium spiny neuron (msn) electrophysiology. |
2023-02-09 |
2023-08-14 |
human |
| Andrey Sequeira-Cordero, Juan C Brene. Time course of plasticity-related alterations following the first exposure to amphetamine in juvenile rats. Pharmacology, biochemistry, and behavior. 2022-11-14. PMID:36375621. |
in a preclinical model with juvenile rats, we analyzed the time-dependent fluctuations in the expression of neuroplasticity-related genes like the brain-derived neurotrophic factor (bdnf), its tropomyosin receptor kinase b (trkb), the camp response element-binding protein (creb), the microrna-132, the rho gtpase-activating protein 32 (p250gap), the corticotropin-releasing factor (crf), and the neurotransmitters contents in the nucleus accumbens (nac) and the dorsal striatum (ds) 45, 90, and 180 min after an amphetamine (amph) injection. |
2022-11-14 |
2023-08-14 |
rat |
| Junichi Yoshida, Maritza Oñate, Leila Khatami, Jorge Vera, Farzan Nadim, Kamran Khodakha. Cerebellar Contributions to the Basal Ganglia Influence Motor Coordination, Reward Processing, and Movement Vigor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 42. issue 45. 2022-11-09. PMID:36351826. |
we then discuss how cerebellar projections to the vta and snc influence dopamine release in the respective targets of these nuclei: the nac and the dorsal striatum. |
2022-11-09 |
2023-08-14 |
Not clear |
| Jameel N Hamdan, Jorge A Sierra-Fonseca, Rodolfo J Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E O'Dell, Kristin L Gosselin. Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner. Frontiers in behavioral neuroscience. vol 16. 2022-11-07. PMID:36338879. |
the hippocampus (hipp), medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate putamen (cpu) were isolated from one subgroup of animals and subjected to western blot and protein quantitation for tyrosine hydroxylase (th), α-synuclein (alpha), nmda receptor (nmdar), dopamine receptor-1 (d1) and -2 (d2), dopamine transporter (dat), and postsynaptic density 95 (psd95). |
2022-11-07 |
2023-08-14 |
rat |
| Armando G Salinas, Jacob A Nadel, Yolanda Mateo, Thanh Huynh, Shana M Augustin, Karel Pacak, David M Lovinge. Chronic Ethanol Consumption Alters Presynaptic Regulation of Dorsal Striatal Dopamine Release in C57BL/6J Mice. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232321. |
like the nac, the dorsal striatum (ds) is implicated in neural and behavioral processes in aud. |
2022-10-14 |
2023-08-14 |
mouse |
| Benjamin Davidson, Peter Giacobbe, Tony P George, Sean M Nestor, Jennifer S Rabin, Maged Goubran, Alexander J Nyman, Anusha Baskaran, Ying Meng, Christopher B Pople, Simon J Graham, Fred Tam, Clement Hamani, Nir Lipsma. Deep brain stimulation of the nucleus accumbens in the treatment of severe alcohol use disorder: a phase I pilot trial. Molecular psychiatry. 2022-07-20. PMID:35858989. |
a potential mechanism underlying this process is a down-regulation of the nac, a disruption of its functional connectivity to the visual association cortex, and interference of cue-elicited dorsal striatum reactivity. |
2022-07-20 |
2023-08-14 |
Not clear |
| Aaron E Miller, Atul P Daiwile, Jean Lud Cade. Sex-Dependent Alterations in the mRNA Expression of Enzymes Involved in Dopamine Synthesis and Breakdown After Methamphetamine Self-Administration. Neurotoxicity research. 2022-07-14. PMID:35834057. |
to better understand the molecular bases for the differences in da metabolism, we measured the levels of mrnas of enzymes that catalyze da synthesis and breakdown in the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (dstr), and hippocampus (hip) of rats that had self-administered meth. |
2022-07-14 |
2023-08-14 |
human |
| Corey Baimel, Emily Jang, Samantha L Scudder, Kasra Manoocheri, Adam G Carte. Hippocampal-evoked inhibition of cholinergic interneurons in the nucleus accumbens. Cell reports. vol 40. issue 1. 2022-07-06. PMID:35793623. |
however, while the activation of chis has been well studied in the dorsal striatum, little is known about how they are engaged in the nac. |
2022-07-06 |
2023-08-14 |
Not clear |
| Tong Zhang, Naoya Nishitani, Kazuhei Niitani, Ryoma Nishida, Yusaku Futami, Satoshi Deyama, Katsuyuki Kaned. A spatiotemporal increase of neuronal activity accompanies the motivational effect of wheel running in mice. Behavioural brain research. 2022-07-01. PMID:35777550. |
immunohistochemical analyses revealed that the number of c-fos (a neuronal activity marker)-positive cells increased in the medial prefrontal cortex (mpfc), core and shell of the nucleus accumbens (nac), dorsal striatum (str), and lateral septum (ls) at day 1, day 9, and days 20-24, in a time-dependent manner. |
2022-07-01 |
2023-08-14 |
mouse |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine. vol 11. issue 11. 2022-06-10. PMID:35683439. |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-08-14 |
mouse |
| Tomoyuki Ijiro, Atsushi Yaguchi, Ayaka Yokoyama, Sumiyoshi Kiguch. Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside-induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission. Clinical and experimental pharmacology & physiology. 2022-05-31. PMID:35637550. |
moreover, rovatirelin significantly increased acetylcholine (ach) levels in the medial prefrontal cortex (mpfc) and dopamine (da) levels in the nucleus accumbens (nac) at ≥3 mg/kg and significantly increased da levels in the dorsal striatum at ≥10 mg/kg in normal rats. |
2022-05-31 |
2023-08-13 |
mouse |
| Tomoyuki Ijiro, Atsushi Yaguchi, Ayaka Yokoyama, Sumiyoshi Kiguch. Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside-induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission. Clinical and experimental pharmacology & physiology. 2022-05-31. PMID:35637550. |
in conclusion, oral administration of rovatirelin ameliorates motor dysfunction in rats with ara-c-induced ataxia, owing to its ach-increasing effects in the mpfc and da-increasing effects in the dorsal striatum and nac. |
2022-05-31 |
2023-08-13 |
mouse |