| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Joseph R Driscoll, Tanya L Wallace, Kasra A Mansourian, William J Martin, Elyssa B Margoli. Differential Modulation of Ventral Tegmental Area Circuits by the Nociceptin/Orphanin FQ System. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32747458. |
n/ofq and its receptor, nop, are enriched in dopaminergic pathways, and intra-ventricular agonist delivery decreases dopamine levels in the dorsal striatum, nucleus accumbens (nac), and ventral tegmental area (vta). |
2021-06-18 |
2023-08-13 |
rat |
| Thomas Contesse, Loïc Broussot, Hugo Fofo, Peter Vanhoutte, Sebastian P Fernandez, Jacques Bari. Dopamine and glutamate receptors control social stress-induced striatal ERK1/2 activation. Neuropharmacology. vol 190. 2021-06-09. PMID:33781778. |
the nucleus accumbens (nac) showed marked increases in perk1/2 following both acute and chronic social stress compared to the dorsal striatum. |
2021-06-09 |
2023-08-13 |
mouse |
| Chiomah Ezeomah, Kathryn A Cunningham, Sonja J Stutz, Robert G Fox, Natalya Bukreyeva, Kelly T Dineley, Slobodan Paessler, Irma E Cisnero. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32165150. |
several innate immune markers, as well as opioid receptors (ors) and intracellular pattern recognition receptors (prrs), were interrogated within nodes of the neurocircuitry involved in oud processes, including the prefrontal cortex (pfc), nucleus accumbens (nac), caudate putamen (cpu), hippocampus (hip) and midbrain (mb). |
2021-04-27 |
2023-08-13 |
rat |
| Patricia Novaes Soares, Rosiane Aparecida Miranda, Iala Milene Bertasso, Carla Bruna Pietrobon, Vanessa Silva Tavares Rodrigues, Elaine de Oliveira, Alex Christian Manhães, Egberto Gaspar de Moura, Patricia Cristina Lisbo. Late effects of early weaning on food preference and the dopaminergic and endocannabinoid systems in male and female rats. Journal of developmental origins of health and disease. 2021-03-02. PMID:33650480. |
at pn180, ew males showed lower type 2 dopamine receptor (d2r) in the nucleus accumbens (nac) and dorsal striatum, while ew females had lower tyrosine hydroxylase in the ventral tegmental area and nac, d1r in the nac, and d2r in the prefrontal cortex. |
2021-03-02 |
2023-08-13 |
rat |
| Xixi Yang, Yichong Wen, Yuxiang Zhang, Feifei Gao, Jingsi Yang, Zhuojin Yang, Chunxia Ya. Dynamic Changes of Cytoskeleton-Related Proteins Within Reward-Related Brain Regions in Morphine-Associated Memory. Frontiers in neuroscience. vol 14. 2021-02-16. PMID:33584180. |
compared with the nac and dorsal hippocampus, dynamic changes in the medial prefrontal cortex (mpfc) and caudate putamen (cpu) were not very significant. |
2021-02-16 |
2023-08-13 |
mouse |
| Mei Huang, Wenqi He, Lakshmi Rajagopal, Andrea Kudwa, Dimitri E Grigoriadis, Herbert Y Meltze. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacology, biochemistry, and behavior. vol 190. 2021-01-07. PMID:32084491. |
we utilized microdialysis in awake, freely moving mice to determine the effect of nbi-98782, the active metabolite of valbenazine, alone, or in combination with several antipsychotic drugs (apds), to influence neurotransmitter efflux in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), hippocampus and nucleus accumbens (nac); we also compared it with tetrabenazine, the prototypical vmat2 inhibitor. |
2021-01-07 |
2023-08-13 |
mouse |
| Johnathan M Borland, Ellen Kim, Samuel P Swanson, Patrick E Rothwell, Paul G Mermelstein, Robert L Meise. Effect of Aggressive Experience in Female Syrian Hamsters on Glutamate Receptor Expression in the Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 14. 2021-01-06. PMID:33328919. |
in the following study, using syrian hamsters as a well-validated and translational model of female aggression, we investigated the effects of aggressive experience on the expression of markers of postsynaptic structure (psd-95, caskin i) and excitatory synaptic transmission (glua1, glua2, glua4, nr2a, nr2b, mglur1a, and mglur5) in the nucleus accumbens (nac), caudate putamen and prefrontal cortex. |
2021-01-06 |
2023-08-13 |
Not clear |
| Gang Chen, Tao Li, Jing Xiao, Jing Wang, Qing Shang, Hongyan Qian, Chuchu Qiao, Ping Zhang, Teng Chen, Xinshe Li. Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization Through the GluN2B-PP2A-AKT Cascade in the Dorsal Striatum of Mice. Neurochemical research. vol 45. issue 4. 2020-12-11. PMID:31981057. |
in this study, we measured the level of phosphorylated (p-) glun2b (serine; ser 1303), pp2a/b (a regulatory subunit of pp2a), and pp2a/c (a catalytic subunit of pp2a) in different brain regions such as the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (ds), and hippocampus (hip). |
2020-12-11 |
2023-08-13 |
mouse |
| Hongliang Su, Tingting Sun, Xiao Wang, Yan Du, Na Zhao, Jie Zhu, Jiangwei Yan, Teng Chen, Keming Yu. Levo-tetrahydropalmatine attenuates methamphetamine reward behavior and the accompanying activation of ERK phosphorylation in mice. Neuroscience letters. vol 714. 2020-12-07. PMID:31398456. |
we then dissected the underlying molecular mechanisms of l-thp in modulating meth-induced cpp by evaluating accompanying changes in expression of phosphorylated extracellular signal-regulated kinase (p-erk) in reward-relevant brain regions, including nucleus accumbens (nac), prefrontal cortex (pfc), caudate putamen (cpu), and hippocampus (hip), which may mediate the effects of l-thp on meth-induced cpp. |
2020-12-07 |
2023-08-13 |
mouse |
| Tae-Kyung Kim, Pyung-Lim Ha. Functional Connectivity of Basolateral Amygdala Neurons Carrying Orexin Receptors and Melanin-concentrating Hormone Receptors in Regulating Sociability and Mood-related Behaviors. Experimental neurobiology. vol 25. issue 6. 2020-10-01. PMID:28035181. |
this axon labeling analysis led us to identify the prelimbic and infralimbic cortices, nucleus accumbens (nac), dorsal striatum, paraventricular nucleus (pvn), interstitial nucleus of the posterior limb of the anterior commissure, habenula, ca3 pyramidal neurons, central amygdala, and ventral hippocampus as the neuroanatomical sites receiving synaptic inputs of bla neurons. |
2020-10-01 |
2023-08-13 |
Not clear |
| Vadim Yuferov, Yong Zhang, Yupu Liang, Connie Zhao, Matthew Randesi, Mary J Kree. Oxycodone Self-Administration Induces Alterations in Expression of Integrin, Semaphorin and Ephrin Genes in the Mouse Striatum. Frontiers in psychiatry. vol 9. 2020-09-29. PMID:29946272. |
the aim of this study is to investigate alterations in expression of selected integrin, semaphorin, ephrins, netrin, and slit genes in the nucleus accumbens (nac) and caudate putamen (cpu) of mice following extended 14-day oxycodone self-administration (sa), using rnaseq. |
2020-09-29 |
2023-08-13 |
mouse |
| Madoka Anan, Ryoko Higa, Kenshiro Shikano, Masahito Shide, Akinobu Soda, Magdeline E Carrasco Apolinario, Kenji Mori, Toshitaka Shin, Mikiya Miyazato, Hiromitsu Mimata, Takatoshi Hikida, Toshikatsu Hanada, Kazuwa Nakao, Kenji Kangawa, Reiko Hanad. Cocaine has some effect on neuromedin U expressing neurons related to the brain reward system. Heliyon. vol 6. issue 5. 2020-09-28. PMID:32462086. |
in this study, we found that some of cocaine-induced c-fos immunoreactive cells were co-localized with nmu in the nucleus accumbens (nac), caudate putamen (cpu), and basolateral amygdala (bla), which are key brain regions associated with the brain reward system, in wild type mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Christopher A Blackwood, Michael Leary, Aaron Salisbury, Michael T McCoy, Jean Lud Cade. Escalated Oxycodone Self-Administration Causes Differential Striatal mRNA Expression of FGFs and IEGs Following Abstinence-Associated Incubation of Oxycodone Craving. Neuroscience. vol 415. 2020-09-23. PMID:31351142. |
the observations that fgf mrna levels were more altered in the dorsal striatum than in the nac of lga rats suggest that changes in striatal fgf expression may be more salient to incubation of oxycodone craving than alterations in the nac. |
2020-09-23 |
2023-08-13 |
rat |
| M Díez-León, L Kitchenham, R Duprey, C D C Bailey, E Choleris, M Lewis, G Maso. Neurophysiological correlates of stereotypic behaviour in a model carnivore species. Behavioural brain research. vol 373. 2020-09-14. PMID:31288059. |
neuronal activity was analysed via cytochrome oxidase (co) staining of the dorsal striatum (caudate; putamen), globus pallidus (externus, gpe; internus, gpi), stn, and nucleus accumbens (nac); and the gpe:gpi ratio (gpr) calculated to assess relative activation of direct and indirect pathways. |
2020-09-14 |
2023-08-13 |
human |
| Jee-Yeon Seo, Kwang-Hyun Hur, Yong-Hyun Ko, Kyungin Kim, Bo-Ram Lee, Young-Jung Kim, Seon-Kyung Kim, Seong-Eon Kim, Yong-Sup Lee, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jan. A novel designer drug, 25N-NBOMe, exhibits abuse potential via the dopaminergic system in rodents. Brain research bulletin. vol 152. 2020-08-14. PMID:31279579. |
in addition, repeated administration of 25 n-nbome did not affect the expression of the dopamine 1 receptor but significantly reduced the expression of the dopamine 2 receptor in both the nucleus accumbens (nac) and the dorsal striatum (dst). |
2020-08-14 |
2023-08-13 |
mouse |
| Anthony Klambatsen, Stephanie K Nygard, Anna J Chang, Vanya Quinones, Shirzad Jena. Sex differences in memory and intracellular signaling after methamphetamine binge treatment. Brain research. vol 1711. 2020-08-04. PMID:30629943. |
neurochemical analysis of the same animals indicated higher levels of fosb protein in caudate-putamen (cpu) and nucleus accumbens (nac) of the male animals than intact or ovx females. |
2020-08-04 |
2023-08-13 |
rat |
| Carles Tapias-Espinosa, Cristóbal Río-Álamos, Ana Sánchez-González, Ignasi Oliveras, Daniel Sampedro-Viana, Maria Del Mar Castillo-Ruiz, Toni Cañete, Adolf Tobeña, Alberto Fernández-Terue. Schizophrenia-like reduced sensorimotor gating in intact inbred and outbred rats is associated with decreased medial prefrontal cortex activity and volume. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 11. 2020-07-06. PMID:30986819. |
relevant structures of the cspt circuit were evaluated, such as the medial prefrontal cortex (mpfc), cingulate cortex, hippocampus (hpc), amygdala, nucleus accumbens (nac), and dorsal striatum. |
2020-07-06 |
2023-08-13 |
rat |
| Lisamon Egenrieder, Ekaterina Mitricheva, Rainer Spanagel, Hamid R Noor. No basal or drug-induced sex differences in striatal dopaminergic levels: a cluster and meta-analysis of rat microdialysis studies. Journal of neurochemistry. vol 152. issue 4. 2020-06-29. PMID:31705667. |
all drugs of abuse, independent of their molecular mechanisms of action, notably increase extracellular dopamine concentrations in the nucleus accumbens (nac) and caudate putamen (cpu). |
2020-06-29 |
2023-08-13 |
rat |
| Julia C Lemos, Jung Hoon Shin, Veronica A Alvare. Striatal Cholinergic Interneurons Are a Novel Target of Corticotropin Releasing Factor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 29. 2020-06-18. PMID:31109960. |
here we report that the stress-associated neuropeptide corticotropin releasing factor (crf) produces a profound and reliable increase in the spontaneous firing of cins in both dorsal striatum and nucleus accumbens (nac) through activation of crf type 1 receptors, production of camp and reduction in spike accommodation in male mice. |
2020-06-18 |
2023-08-13 |
mouse |