| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Chambers, J N McClintick, A M Sentir, S A Berg, M Runyan, K H Choi, H J Edenber. Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes, brain, and behavior. vol 12. issue 5. 2014-01-27. PMID:23682998. |
rat genome-wide microarrays containing >24 000 probesets were used to examine separate and co-occurring effects of nvhls and cocaine sensitization (15 mg/kg/day × 5 days) on gene expression within medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate-putamen (capu). |
2014-01-27 |
2023-08-12 |
rat |
| Ying-Chou Wang, Yu-Chi Yeh, Chia-Chuan Wang, Sigmund Hsiao, Chin-Cheng Lee, Andrew Chih Wei Huan. Neural substrates of amphetamine-induced behavioral sensitization: unconditioned (zero context) and conditioned (switch versus same context) components in c-fos overexpression. Neuropsychobiology. vol 67. issue 1. 2013-06-06. PMID:23222036. |
(c) the other nuclei, including the medial prefrontal cortex, nucleus accumbens, caudate putamen, medial thalamus, hippocampus, amygdala, and ventral tegmental area, are activated in all contextual conditions and the pure amph effect (the zero context). |
2013-06-06 |
2023-08-12 |
rat |
| Hanafi A Damanhuri, Peter G R Burke, Lin K Ong, Larisa Bobrovskaya, Phillip W Dickson, Peter R Dunkley, Ann K Goodchil. Tyrosine hydroxylase phosphorylation in catecholaminergic brain regions: a marker of activation following acute hypotension and glucoprivation. PloS one. vol 7. issue 11. 2013-05-22. PMID:23209770. |
conscious rats were subjected to hypotension, glucoprivation or vehicle for 30, 60 or 120 min and changes in the phosphorylation of serine residues 19, 31 and 40 in the biosynthetic enzyme, tyrosine hydroxylase (th), the activity of th and/or, the expression of c-fos were determined, in up to ten brain regions simultaneously that contain catecholaminergic cell bodies and/or terminals: a1, a2, caudal c1, rostral c1, a6, a8/9, a10, nucleus accumbens, dorsal striatum and medial prefrontal cortex. |
2013-05-22 |
2023-08-12 |
rat |
| Florence R M Theberge, Charles L Pickens, Evan Goldart, Sanya Fanous, Bruce T Hope, Qing-Rong Liu, Yavin Shaha. Association of time-dependent changes in mu opioid receptor mRNA, but not BDNF, TrkB, or MeCP2 mRNA and protein expression in the rat nucleus accumbens with incubation of heroin craving. Psychopharmacology. vol 224. issue 4. 2013-05-10. PMID:22790874. |
we investigated whether this incubation is associated with time-dependent changes in brain-derived neurotrophic factor (bdnf) and methyl-cpg binding protein 2 (mecp2) signaling and mu opioid receptor (mor) expression in nucleus accumbens (nac), dorsal striatum (ds), and medial prefrontal cortex (mpfc). |
2013-05-10 |
2023-08-12 |
rat |
| J Luigjes, W van den Brink, M Feenstra, P van den Munckhof, P R Schuurman, R Schippers, A Mazaheri, T J De Vries, D Deny. Deep brain stimulation in addiction: a review of potential brain targets. Molecular psychiatry. vol 17. issue 6. 2012-11-07. PMID:21931318. |
we found 7 animal studies targeting six different brain areas: nucleus accumbens (nac), subthalamic nucleus (stn), dorsal striatum, lateral habenula, medial prefrontal cortex (mpfc) and hypothalamus, and 11 human studies targeting two different target areas: nac and stn. |
2012-11-07 |
2023-08-12 |
human |
| Tobias Brosch, Géraldine Coppin, Sophie Schwartz, David Sande. The importance of actions and the worth of an object: dissociable neural systems representing core value and economic value. Social cognitive and affective neuroscience. vol 7. issue 5. 2012-10-30. PMID:21642352. |
core value computations activated medial prefrontal cortex, a region involved in the processing of self-relevant information and dorsal striatum, involved in action selection. |
2012-10-30 |
2023-08-12 |
Not clear |
| Andrew M Novick, Gina L Forster, Shanaz M Tejani-Butt, Michael J Wat. Adolescent social defeat alters markers of adult dopaminergic function. Brain research bulletin. vol 86. issue 1-2. 2012-04-04. PMID:21741457. |
our results indicate that social defeat during adolescence led to higher dopamine transporter binding in the infralimbic region of the medial prefrontal cortex and higher dopamine d1 receptor binding in the caudate putamen, while other brain regions analyzed were comparable to controls. |
2012-04-04 |
2023-08-12 |
rat |
| A R Burke, M J Watt, G L Forste. Adolescent social defeat increases adult amphetamine conditioned place preference and alters D2 dopamine receptor expression. Neuroscience. vol 197. 2012-02-27. PMID:21933700. |
we measured d1 and d2 dopamine receptor protein content in the medial prefrontal cortex, nucleus accumbens (nac), and dorsal striatum following either adolescent social defeat or foot-shock stress and then adult amphetamine cpp. |
2012-02-27 |
2023-08-12 |
human |
| Y Pan, L Chau, S Liu, M V Avshalumov, M E Rice, K D Car. A food restriction protocol that increases drug reward decreases tropomyosin receptor kinase B in the ventral tegmental area, with no effect on brain-derived neurotrophic factor or tropomyosin receptor kinase B protein levels in dopaminergic forebrain regions. Neuroscience. vol 197. 2012-02-27. PMID:21945647. |
three to four weeks of fr, with stabilization of rats at 80% of initial body weight, did not alter bdnf or trkb levels in nucleus accumbens, caudate-putamen, or medial prefrontal cortex. |
2012-02-27 |
2023-08-12 |
human |
| Li-Min Mao, Erica Horton, Ming-Lei Guo, Bing Xue, Dao-Zhong Jin, Eugene E Fibuch, John Q Wan. Cocaine increases phosphorylation of MeCP2 in the rat striatum in vivo: a differential role of NMDA receptors. Neurochemistry international. vol 59. issue 5. 2012-01-12. PMID:21704097. |
we found that acute systemic injection of cocaine increased mecp2 phosphorylation at s421 in the rat striatum, including both the caudate putamen and the nucleus accumbens, while cocaine did not affect mecp2 phosphorylation in the medial prefrontal cortex. |
2012-01-12 |
2023-08-12 |
human |
| Li Chen, Jian Liu, Qiao Jun Zhang, Jian Jun Feng, Zhen Hua Gui, Umar Ali, Yong Wang, Ling Ling Fan, Chen Hou, Tao Wan. Alterations of emotion, cognition and firing activity of the basolateral nucleus of the amygdala after partial bilateral lesions of the nigrostriatal pathway in rats. Brain research bulletin. vol 85. issue 6. 2012-01-11. PMID:21624440. |
in the present study, we examined the changes in emotional and cognitive tests not focused on motor fluency and firing activity of projection neurons in the bla rats with 6-hydroxydopamine (6-ohda) injected bilaterally into dorsal striatum, and the effects of apomorphine and the medial prefrontal cortex (mpfc) on these changes. |
2012-01-11 |
2023-08-12 |
rat |
| Richard J Beninger, Tyson W Baker, Matthew M Florczynski, Tomek J Banasikowsk. Regional differences in the action of antipsychotic drugs: implications for cognitive effects in schizophrenic patients. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20376711. |
evidence from immediate early gene immunohistochemical, electrophysiological, microdialysis, imaging, and behavioral studies suggests that typical apds preferentially affect the nucleus accumbens (nac) and the dorsal striatum while atypical apds preferentially affect the nac and medial prefrontal cortex (pfc). |
2011-09-15 |
2023-08-12 |
Not clear |
| Nurgul Carkaci-Salli, Ugur Salli, Kara L Kuntz-Melcavage, Michael M Pennock, Hande Ozgen, Izel Tekin, Willard M Freeman, Kent E Vran. TPH2 in the ventral tegmental area of the male rat brain. Brain research bulletin. vol 84. issue 6. 2011-07-18. PMID:21272616. |
in the present study, we assessed the levels of mrna, protein expression, and enzyme activity of tph2 in the rat raphe, ventral tegmental area (vta), substantia nigra, hippocampus, cerebellum, dorsal striatum, nucleus accumbens, amygdala, and medial prefrontal cortex to more fully understand the distribution of this enzyme throughout the central nervous system. |
2011-07-18 |
2023-08-12 |
rat |
| L Pozzi, M Baviera, G Sacchetti, E Calcagno, C Balducci, R W Invernizzi, M Carl. Attention deficit induced by blockade of N-methyl D-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response element binding protein phosphorylation: role of metabotropic glutamate receptors 2/3. Neuroscience. vol 176. 2011-06-01. PMID:21193020. |
in parallel studies using microdialysis technique and western blot analysis we found that (r)-cpp (100 μm) infused in the medial prefrontal cortex increased glutamate efflux whereas injected in the medial prefrontal cortex at a dose causing impairments in attentional performance (50 ng/side) increased p-s(133)creb in the frontal cortex (fc), decreased it in the caudate-putamen (cpu) and was without effect in the nucleus accumbens (nac). |
2011-06-01 |
2023-08-12 |
rat |
| Kimberly A Young, Yan Liu, Kyle L Gobrogge, David M Dietz, Hui Wang, Mohamed Kabbaj, Zuoxin Wan. Amphetamine alters behavior and mesocorticolimbic dopamine receptor expression in the monogamous female prairie vole. Brain research. vol 1367. 2011-04-15. PMID:20933511. |
we also found that exposure to a behaviorally relevant dose of amph (1.0 mg/kg) induced an increase in da concentration in the nucleus accumbens (nacc) and caudate putamen but not the medial prefrontal cortex or ventral tegmental area (vta). |
2011-04-15 |
2023-08-12 |
Not clear |
| K K Pitchers, K S Frohmader, V Vialou, E Mouzon, E J Nestler, M N Lehman, L M Coole. ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward. Genes, brain, and behavior. vol 9. issue 7. 2011-02-08. PMID:20618447. |
sexual experience was shown to cause Δfosb accumulation in several limbic brain regions including the nucleus accumbens (nac), medial prefrontal cortex, ventral tegmental area and caudate putamen but not the medial preoptic nucleus. |
2011-02-08 |
2023-08-12 |
rat |
| David H Root, Anthony T Fabbricatore, Sisi Ma, David J Barker, Mark O Wes. Rapid phasic activity of ventral pallidal neurons during cocaine self-administration. Synapse (New York, N.Y.). vol 64. issue 9. 2010-10-19. PMID:20340176. |
this is especially important given that pallidothalamic and pallidomesencephalic vp projections are positioned to alter dopaminoceptive targets such as the medial prefrontal cortex, nucleus accumbens, and dorsal striatum, all of which have roles in cocaine self-administration. |
2010-10-19 |
2023-08-12 |
rat |
| Argel Aguilar-Valles, Cecilia Flores, Giamal N Luhesh. Prenatal inflammation-induced hypoferremia alters dopamine function in the adult offspring in rat: relevance for schizophrenia. PloS one. vol 5. issue 6. 2010-09-01. PMID:20532043. |
in addition we measured protein levels of tyrosine hydroxylase, and tissue levels of dopamine and its metabolites, in ventral tegmental area, susbtantia nigra, nucleus accumbens, dorsal striatum and medial prefrontal cortex. |
2010-09-01 |
2023-08-12 |
rat |
| Feng Shao, Jian Jin, Qingxuan Meng, Mei Liu, Xi Xie, Wenjuan Lin, Weiwen Wan. Pubertal isolation alters latent inhibition and DA in nucleus accumbens of adult rats. Physiology & behavior. vol 98. issue 3. 2009-10-27. PMID:19527740. |
after the behavioral test, dopamine (da) levels were measured in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), caudate-putamen (cpu), and the hippocampus (hip). |
2009-10-27 |
2023-08-12 |
rat |
| Frank I Tarazi, Yong Kee Choi, Matthew Gardner, Erik H F Wong, Brian Henry, Mohammed Shahi. Asenapine exerts distinctive regional effects on ionotropic glutamate receptor subtypes in rat brain. Synapse (New York, N.Y.). vol 63. issue 5. 2009-06-17. PMID:19177511. |
brain sections were collected from the medial prefrontal cortex (mpfc), dorsolateral frontal cortex, caudate putamen (cpu), nucleus accumbens (nac), and hippocampus (hip), and processed for in vitro receptor autoradiography. |
2009-06-17 |
2023-08-12 |
human |