| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
the present study demonstrated for the first time that acute as well as subchronic (4\xe2\x80\xafdays) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3\xe2\x80\xafmg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the \xce\xb2-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-03-06 |
rat |
| Ryan P Bell, Sheri L Towe, Kareem Al-Khalil, Matthew Gibson, Tauseef Nadeem, Christina S Mead. Additive cortical gray matter deficits in people living with HIV who use cocaine. Journal of neurovirology vol issue 2023 36787045 |
within subcortical regions, cocaine use was independently associated with higher volume in the dorsal striatum and pallidum, while hiv disease was associated with lower volume in the nucleus accumbens and thalamus. |
2023-02-14 |
2023-03-06 |
human |
| Qing Zhai, Ariful Islam, Bin Chen, Hengsen Zhang, Do Huu Chi, Md Al Mamun, Yutaka Takahashi, Noriko Sato, Hidenori Yamasue, Yoshiki Nakajima, Yu Nagashima, Fumito Sano, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Seto. Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. Cells vol 12 issue 3 2023 36766735 |
however, the detailed spatial distribution of 2-ag and its changes by crs in stress processing-related anatomical structures such as the anterior cingulate cortex (acc), caudate putamen (cp), nucleus accumbens (nac), and piriform cortex (pir) are still unclear. |
2023-02-11 |
2023-03-06 |
mouse |
| Anna L S Beeson, John Meitze. Estrous cycle impacts on dendritic spine plasticity in rat nucleus accumbens core and shell and caudate-putamen. The Journal of comparative neurology vol issue 2023 36756791 |
considering the striatal brain regions, the nucleus accumbens (nac) core, nac shell, and caudate-putamen (cpu), the estrous cycle has previously been shown to impact relevant behaviors and disorders, neuromodulator action, and medium spiny neuron (msn) electrophysiology. |
2023-02-09 |
2023-03-06 |
rat |
| Marie-Louise Allingbjerg, Stine N Hansen, Anna Secher, Morgane Thomse. Glucagon-like peptide-1 receptors in nucleus accumbens, ventral hippocampus, and lateral septum reduce alcohol reinforcement in mice. Experimental and clinical psychopharmacology vol issue 2022 36480394 |
infusion of exendin-4 into the nucleus accumbens also reduced alcohol self-administration, as anticipated based on earlier reports, while infusion of exendin-4 into the caudate-putamen (dorsal striatum) had little effect, consistent with lack of glp-1 receptor expression in this region. |
2022-12-08 |
2023-01-30 |
mouse |
| Andrey Sequeira-Cordero, Juan C Brene. Time course of plasticity-related alterations following the first exposure to amphetamine in juvenile rats. Pharmacology, biochemistry, and behavior vol issue 2022 36375621 |
in a preclinical model with juvenile rats, we analyzed the time-dependent fluctuations in the expression of neuroplasticity-related genes like the brain-derived neurotrophic factor (bdnf), its tropomyosin receptor kinase b (trkb), the camp response element-binding protein (creb), the microrna-132, the rho gtpase-activating protein 32 (p250gap), the corticotropin-releasing factor (crf), and the neurotransmitters contents in the nucleus accumbens (nac) and the dorsal striatum (ds) 45, 90, and 180\xe2\x80\xafmin after an amphetamine (amph) injection. |
2022-11-14 |
2023-01-30 |
rat |
| Jameel N Hamdan, Jorge A Sierra-Fonseca, Rodolfo J Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E O'Dell, Kristin L Gosselin. Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner. Frontiers in behavioral neuroscience vol 16 issue 2022 36338879 |
the hippocampus (hipp), medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate putamen (cpu) were isolated from one subgroup of animals and subjected to western blot and protein quantitation for tyrosine hydroxylase (th), \xce\xb1-synuclein (alpha), nmda receptor (nmdar), dopamine receptor-1 (d1) and -2 (d2), dopamine transporter (dat), and postsynaptic density 95 (psd95). |
2022-11-07 |
2023-01-30 |
rat |
| Cheryl A Hawkes, Christopher J Heath, Matthew M Sharp, Dariusz C G\\xc3\\xb3recki, Roxana O Carar. \\xce\\xb1-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression. Acta neuropathologica communications vol 10 issue 1 2022 36045406 |
mrna levels of mor1were significantly decreased in the caudate-putamen and nucleus accumbens of \xce\xb1-db ko compared to wt animals, but protein levels were unaltered. |
2022-08-31 |
2023-01-30 |
mouse |
| Aaron E Miller, Atul P Daiwile, Jean Lud Cade. Sex-Dependent Alterations in the mRNA Expression of Enzymes Involved in Dopamine Synthesis and Breakdown After Methamphetamine Self-Administration. Neurotoxicity research vol issue 2022 35834057 |
to better understand the molecular bases for the differences in da metabolism, we measured the levels of mrnas of enzymes that catalyze da synthesis and breakdown in the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (dstr), and hippocampus (hip) of rats that had self-administered meth. |
2022-07-14 |
2023-01-27 |
rat |
| Tong Zhang, Naoya Nishitani, Kazuhei Niitani, Ryoma Nishida, Yusaku Futami, Satoshi Deyama, Katsuyuki Kaned. A spatiotemporal increase of neuronal activity accompanies the motivational effect of wheel running in mice. Behavioural brain research vol issue 2022 35777550 |
immunohistochemical analyses revealed that the number of c-fos (a neuronal activity marker)-positive cells increased in the medial prefrontal cortex (mpfc), core and shell of the nucleus accumbens (nac), dorsal striatum (str), and lateral septum (ls) at day 1, day 9, and days 20-24, in a time-dependent manner. |
2022-07-01 |
2023-01-27 |
mouse |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine vol 11 issue 11 2022 35683439 |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-01-27 |
mouse |
| Tomoyuki Ijiro, Atsushi Yaguchi, Ayaka Yokoyama, Sumiyoshi Kiguch. Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside-induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission. Clinical and experimental pharmacology & physiology vol issue 2022 35637550 |
moreover, rovatirelin significantly increased acetylcholine (ach) levels in the medial prefrontal cortex (mpfc) and dopamine (da) levels in the nucleus accumbens (nac) at \xe2\x89\xa53 mg/kg and significantly increased da levels in the dorsal striatum at \xe2\x89\xa510 mg/kg in normal rats. |
2022-05-31 |
2023-01-27 |
rat |
| Suzannah De Almeida, Gregory Sarto. BET proteins as novel epigenetic targets for the treatment of Opioid Use Disorder. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 36 Suppl 1 issue 2022 35555955 |
to assess a potential role for bet proteins in oud, we measured time-dependent changes in bet mrna expression in the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds), following oral oxycodone self-administration. |
2022-05-13 |
2023-01-27 |
mouse |
| Eugenia V Gurevic. Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System. Current topics in behavioral neurosciences vol issue 2022 35505061 |
additionally, in the rodent brain, the d3r in the dorsal striatum appears to be co-expressed with the d1 dopamine receptor-bearing striatal neurons giving rise to the direct output striatal pathway, although the picture is less clear with respect to the nucleus accumbens. |
2022-05-03 |
2023-01-27 |
rat |
| Atul P Daiwile, Patricia Sullivan, Subramaniam Jayanthi, David S Goldstein, Jean Lud Cade. Sex-Specific Alterations in Dopamine Metabolism in the Brain after Methamphetamine Self-Administration. International journal of molecular sciences vol 23 issue 8 2022 35457170 |
dopamine and its metabolites were measured in the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (dstr), and hippocampus (hip). |
2022-04-23 |
2023-01-27 |
rat |
| G E Pennacchio, F E Santonja, F J Neira, C Bregonzio, M Soaj. Prenatal Amphetamine-Induced Dopaminergic Alteration in a Gender- and Estrogen-Dependent Manner. Neurochemical research vol issue 2022 35147850 |
we evaluated the effects of prenatal amphetamine exposure on locomotor activity, dopamine receptors and tyrosine hydroxylase mrna expression in nucleus accumbens and caudate-putamen in response to amphetamine challenge in adult female and male rats. |
2022-02-11 |
2023-01-27 |
rat |
| G E Pennacchio, F E Santonja, F J Neira, C Bregonzio, M Soaj. Prenatal Amphetamine-Induced Dopaminergic Alteration in a Gender- and Estrogen-Dependent Manner. Neurochemical research vol issue 2022 35147850 |
nucleus accumbens and caudate-putamen were processed for mrna determination by real-time pcr. |
2022-02-11 |
2023-01-27 |
rat |
| Scott Edwards, Chelsea N Callicoatte, Angela E Barattini, Jessica A Cucinello-Ragland, Alex Melain, Kimberly N Edwards, Nicholas W Gilpin, Elizabeth M Avegno, Amanda R Pahn. Pramipexole treatment attenuates mechanical hypersensitivity in male rats experiencing chronic inflammatory pain. Neuropharmacology vol issue 2022 35085583 |
we also examined the effects of pramipexole treatment on glutamatergic and presynaptic signaling in pain- and reward-related brain regions including the nucleus accumbens (nac), dorsal striatum (ds), ventral tegmental area (vta), cingulate cortex (cc), central amygdala (cea), and periaqueductal gray (pag). |
2022-01-27 |
2023-01-27 |
rat |
| Yingying Yang, Quan Zhang, Jialiang Ren, Qingfeng Zhu, Lixin Wang, Yongzhi Zhang, Zuojun Gen. Evolution of Brain Morphology in Spontaneously Hypertensive and Wistar-Kyoto Rats From Early Adulthood to Aging: A Longitudinal Magnetic Resonance Imaging Study. Frontiers in aging neuroscience vol 13 issue 2021 34916922 |
we identified the vulnerable gray matter volume with combined effects of hypertension and aging in the septal region, bilateral caudate putamen, hippocampus, primary somatosensory cortex, cerebellum, periaqueductal gray, right accumbens nucleus, and thalamus. |
2021-12-17 |
2023-01-26 |
rat |
| Kevin Clare, Chelsea Pan, Gloria Kim, Kicheon Park, Juan Zhao, Nora D Volkow, Zhicheng Lin, Congwu D. Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects. Frontiers in pharmacology vol 12 issue 2021 33912043 |
here, we investigated changes in the total neuronal density and relative concentration of d2r-expressing neurons in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), nucleus accumbens (nac), and ventral tegmental area (vta) in both male and female mice passively exposed to cocaine for two weeks. |
2021-12-12 |
2023-01-26 |
mouse |