| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cai-N Cheng, Shaw-Jye Wu, Andrew Chih Wei Huan. Environmental Enrichment Components Required to Reduce Methamphetamine-Induced Behavioral Sensitization in Mice: Examination of Behaviors and Neural Substrates. Journal of clinical medicine. vol 11. issue 11. 2022-06-10. PMID:35683439. |
the c-fos expression analysis showed that the medial prefrontal cortex (i.e., cingulate cortex 1 (cg1), prelimbic cortex (prl), and infralimbic cortex (il)), nucleus accumbens (nac), basolateral amygdala (bla), ventral tegmental area (vta), caudate-putamen (cpu), and hippocampus (i.e., ca1, ca3, and dentate gyrus (dg)) contributed to mamph-induced behavioral sensitization. |
2022-06-10 |
2023-08-14 |
mouse |
| Tomoyuki Ijiro, Atsushi Yaguchi, Ayaka Yokoyama, Sumiyoshi Kiguch. Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside-induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission. Clinical and experimental pharmacology & physiology. 2022-05-31. PMID:35637550. |
moreover, rovatirelin significantly increased acetylcholine (ach) levels in the medial prefrontal cortex (mpfc) and dopamine (da) levels in the nucleus accumbens (nac) at ≥3 mg/kg and significantly increased da levels in the dorsal striatum at ≥10 mg/kg in normal rats. |
2022-05-31 |
2023-08-13 |
mouse |
| Suzannah De Almeida, Gregory Sarto. BET proteins as novel epigenetic targets for the treatment of Opioid Use Disorder. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555955. |
to assess a potential role for bet proteins in oud, we measured time-dependent changes in bet mrna expression in the prefrontal cortex (pfc), nucleus accumbens (nac), and dorsal striatum (ds), following oral oxycodone self-administration. |
2022-05-13 |
2023-08-13 |
mouse |
| Eugenia V Gurevic. Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System. Current topics in behavioral neurosciences. 2022-05-03. PMID:35505061. |
additionally, in the rodent brain, the d3r in the dorsal striatum appears to be co-expressed with the d1 dopamine receptor-bearing striatal neurons giving rise to the direct output striatal pathway, although the picture is less clear with respect to the nucleus accumbens. |
2022-05-03 |
2023-08-13 |
human |
| Atul P Daiwile, Patricia Sullivan, Subramaniam Jayanthi, David S Goldstein, Jean Lud Cade. Sex-Specific Alterations in Dopamine Metabolism in the Brain after Methamphetamine Self-Administration. International journal of molecular sciences. vol 23. issue 8. 2022-04-23. PMID:35457170. |
dopamine and its metabolites were measured in the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (dstr), and hippocampus (hip). |
2022-04-23 |
2023-08-13 |
rat |
| G E Pennacchio, F E Santonja, F J Neira, C Bregonzio, M Soaj. Prenatal Amphetamine-Induced Dopaminergic Alteration in a Gender- and Estrogen-Dependent Manner. Neurochemical research. 2022-02-11. PMID:35147850. |
we evaluated the effects of prenatal amphetamine exposure on locomotor activity, dopamine receptors and tyrosine hydroxylase mrna expression in nucleus accumbens and caudate-putamen in response to amphetamine challenge in adult female and male rats. |
2022-02-11 |
2023-08-13 |
rat |
| Scott Edwards, Chelsea N Callicoatte, Angela E Barattini, Jessica A Cucinello-Ragland, Alex Melain, Kimberly N Edwards, Nicholas W Gilpin, Elizabeth M Avegno, Amanda R Pahn. Pramipexole treatment attenuates mechanical hypersensitivity in male rats experiencing chronic inflammatory pain. Neuropharmacology. 2022-01-27. PMID:35085583. |
we also examined the effects of pramipexole treatment on glutamatergic and presynaptic signaling in pain- and reward-related brain regions including the nucleus accumbens (nac), dorsal striatum (ds), ventral tegmental area (vta), cingulate cortex (cc), central amygdala (cea), and periaqueductal gray (pag). |
2022-01-27 |
2023-08-13 |
rat |
| Kevin Clare, Chelsea Pan, Gloria Kim, Kicheon Park, Juan Zhao, Nora D Volkow, Zhicheng Lin, Congwu D. Cocaine Reduces the Neuronal Population While Upregulating Dopamine D2-Receptor-Expressing Neurons in Brain Reward Regions: Sex-Effects. Frontiers in pharmacology. vol 12. 2021-12-12. PMID:33912043. |
here, we investigated changes in the total neuronal density and relative concentration of d2r-expressing neurons in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), nucleus accumbens (nac), and ventral tegmental area (vta) in both male and female mice passively exposed to cocaine for two weeks. |
2021-12-12 |
2023-08-13 |
mouse |
| Nurul H M Yusoff, Zurina Hassan, Vikneswaran Murugaiyah, Christian P Mülle. The effect of mitragynine on extracellular activity of brain dopamine and its metabolites. Brain research bulletin. vol 178. 2021-12-09. PMID:34774992. |
affects extracellular activity of dopamine (da) and its metabolites, 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) in the prefrontal cortex (pfc), nucleus accumbens (nac) and caudate putamen (cpu) of the brain, compared to morphine (mor; 10 mg/kg, i.p.) |
2021-12-09 |
2023-08-13 |
rat |
| Guillermo Valera-Marín, Larry J Young, Francisco Camacho, Raúl G Paredes, Verónica M Rodríguez, Néstor F Díaz, Wendy Portill. Raised without a father: monoparental care effects over development, sexual behavior, sexual reward, and pair bonding in prairie voles. Behavioural brain research. vol 408. 2021-12-07. PMID:33775781. |
we also measured dopamine and serotonin concentration in the nucleus accumbens (ventral striatum) and dorsal striatum after cohabitation and mating (cm) to determine if differences in these neurotransmitters could underlie the delay in pair bond formation in mp voles. |
2021-12-07 |
2023-08-13 |
Not clear |
| Mijung Yeom, Sora Ahn, Ju-Young Oh, Song-Yi Kim, Hyangsook Lee, Dae-Hyun Hahm, Hi-Joon Par. Atopic dermatitis induces anxiety- and depressive-like behaviors with concomitant neuronal adaptations in brain reward circuits in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 98. 2021-11-22. PMID:31743694. |
in the nucleus accumbens (nac), dorsal striatum (ds) and ventral tegmental area (vta), protein levels of dopamine- and plasticity-related signaling molecules were determined by western immunoblotting assay. |
2021-11-22 |
2023-08-13 |
mouse |
| Benoit Forget, Elena Martin Garcia, Arthur Godino, Laura Domingo Rodriguez, Vincent Kappes, Pierre Poirier, Andry Andrianarivelo, Eric Senabre Marchan, Marie-Charlotte Allichon, Mélanie Marias, Peter Vanhoutte, Jean-Antoine Girault, Rafael Maldonado, Jocelyne Caboch. Cell-type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons. Molecular psychiatry. 2021-11-17. PMID:34785784. |
here, we evaluated the expression of a subset of mirnas proposed to modulate cocaine effects in the nucleus accumbens (nac) and dorsal striatum (ds) upon sustained cocaine exposure in mice and showed that these selected mirnas were preferentially upregulated in the nac. |
2021-11-17 |
2023-08-13 |
mouse |
| Forrest D Rogers, Sara M Freeman, Marina Anderson, Michelle C Palumbo, Karen L Bale. Compositional variation in early-life parenting structures alters oxytocin and vasopressin 1a receptor development in prairie voles (Microtus ochrogaster). Journal of neuroendocrinology. vol 33. issue 8. 2021-11-16. PMID:34189787. |
compared to biparentally reared controls (bpc), male offspring reared in mother only (mon) and maternal-plus-alloparental (mpa) conditions show lower densities of oxtr in the central amygdala; and mpa males show lower densities of oxtr in the caudate putamen and nucleus accumbens. |
2021-11-16 |
2023-08-13 |
Not clear |
| Maria Vrettou, Liying Yan, Kent W Nilsson, Åsa Wallén-Mackenzie, Ingrid Nylander, Erika Comasc. DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34321562. |
the present study aimed to investigate whether dna methylation of the vesicular glutamate transporters (vglut)1-3 is related to previously observed vglut1-3 transcriptional differences in the ventral tegmental area (vta), nucleus accumbens (acb), dorsal striatum (dstr) and medial prefrontal cortex (mpfc) of adult rats exposed to els, modelled by maternal separation, and voluntary ethanol consumption. |
2021-11-08 |
2023-08-13 |
rat |
| Andrey Sequeira-Cordero, Juan C Brene. Time-dependent changes in striatal monoamine levels and gene expression following single and repeated amphetamine administration in rats. European journal of pharmacology. vol 904. 2021-11-05. PMID:33961872. |
we measured the mrna levels of the brain-derived neurotrophic factor (bdnf), its tropomyosin receptor kinase b (trkb), the camp response element-binding protein (creb), the microrna-132, the rho gtpase-activating protein 32 (p250gap), the corticotropin-releasing factor (crf), and monoamines and amino-acids contents in the nucleus accumbens and the dorsal striatum 45, 90, and 180 min after the last injection. |
2021-11-05 |
2023-08-13 |
human |
| Akira Mizoguchi, Ryoichi Banno, Runan Sun, Hiroshi Yaginuma, Keigo Taki, Tomoko Kobayashi, Mariko Sugiyama, Taku Tsunekawa, Takeshi Onoue, Hiroshi Takagi, Daisuke Hagiwara, Yoshihiro Ito, Shintaro Iwama, Hidetaka Suga, Taku Nagai, Kiyofumi Yamada, Hiroshi Arim. Glucocorticoid receptor signaling in ventral tegmental area neurons increases the rewarding value of a high-fat diet in mice. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34145364. |
the reward system, which consists of dopaminergic neurons projecting from the ventral tegmental area (vta) to the nucleus accumbens and caudate-putamen in the striatum, has an important role in the pathogenesis of not only drug addiction but also diet-induced obesity. |
2021-11-05 |
2023-08-13 |
mouse |
| Dinesh Y Gawande, Gajanan P Shelkar, Jinxu Liu, Anna D Ayala, Ratnamala Pavuluri, Diane Choi, Yoland Smith, Shashank M Dravi. Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors. Molecular neurobiology. vol 58. issue 10. 2021-10-27. PMID:34173171. |
loss of glud1 leads to reduced excitatory neurotransmission in medium spiny neurons (msns) in the dorsal striatum, but not in the ventral striatum (both core and shell of the nucleus accumbens (nac)). |
2021-10-27 |
2023-08-13 |
Not clear |
| Barbara Ziółkowsk. The Role of Mesostriatal Dopamine System and Corticostriatal Glutamatergic Transmission in Chronic Pain. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679376. |
the first part of the present article reviews the evidence indicating that dopamine exerts analgesic effects during persistent pain by stimulating the d2 receptors in the dorsal striatum and nucleus accumbens (nac). |
2021-10-26 |
2023-08-13 |
Not clear |
| Francis K Maina, Tiffany A Mathew. A functional fast scan cyclic voltammetry assay to characterize dopamine D2 and D3 autoreceptors in the mouse striatum. ACS chemical neuroscience. vol 1. issue 6. 2021-10-20. PMID:20567609. |
the dopamine d2 agonists (-)-quinpirole hydrochloride and 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-4h-thiazolo[4,5-d]azepin-2-amine dihydrochloride (b-ht 920) had the same dopamine release inhibition effects on caudate-putamen and nucleus accumbens (core and shell) based on their ec(50) and efficacies. |
2021-10-20 |
2023-08-12 |
mouse |
| Francis K Maina, Tiffany A Mathew. A functional fast scan cyclic voltammetry assay to characterize dopamine D2 and D3 autoreceptors in the mouse striatum. ACS chemical neuroscience. vol 1. issue 6. 2021-10-20. PMID:20567609. |
neither dopamine d2 nor d3 agonists affected the uptake rates in nucleus accumbens but concentrations greater than 0.3 mum lowered the uptake rate in caudate-putamen. |
2021-10-20 |
2023-08-12 |
mouse |