| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hajime Miyanishi, Atsumi Nitt. A Role of BDNF in the Depression Pathogenesis and a Potential Target as Antidepressant: The Modulator of Stress Sensitivity "Shati/Nat8l-BDNF System" in the Dorsal Striatum. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577589. |
we reviewed a novel finding of bdnf function in the dorsal striatum, which induces vulnerability to social stress, in addition to recent research progress regarding the brain regional functions of bdnf, including the prefrontal cortex, hippocampus, and nucleus accumbens. |
2021-10-01 |
2023-08-13 |
Not clear |
| Julie Boulanger-Bertolus, Sandrine Parrot, Valérie Doyère, Anne-Marie Moul. Dorsal striatum and the temporal expectancy of an aversive event in Pavlovian odor fear learning. Neurobiology of learning and memory. vol 182. 2021-09-22. PMID:33915299. |
our data further suggest that the conditioning and the learning of a novel time interval were associated with a decrease in dopamine level in the dorsal striatum, but not in the nucleus accumbens. |
2021-09-22 |
2023-08-13 |
rat |
| Todd H Ahern, Sara Olsen, Ryan Tudino, Annaliese K Beer. Natural variation in the oxytocin receptor gene and rearing interact to influence reproductive and nonreproductive social behavior and receptor binding. Psychoneuroendocrinology. vol 128. 2021-09-16. PMID:33839431. |
in line with previous literature, c/t animals exhibited higher densities of oxytocin receptor (oxtr) in the striatum (caudoputamen, nucleus accumbens) compared to t/t subjects. |
2021-09-16 |
2023-08-13 |
human |
| Qing Shang, Jing Xiao, Baoyao Gao, Min Liang, Jing Wang, Hongyan Qian, Zhijia Xi, Tao Li, Xinshe Li. D1R/PP2A/p-CaMKIIα signaling in the caudate putamen is involved in acute methamphetamine-induced hyperlocomotion. Neuroscience letters. vol 760. 2021-08-17. PMID:34237414. |
the protein levels of methylated pp2a-c (m-pp2a-c, leucine [leu] 309), phosphorylated pp2a-c (p-pp2a-c, tyrosine [tyr] 307), pp2a-c, p-camkiiα (thr 286), and camkiiα in the prefrontal cortex (pfc), nucleus accumbens (nac), and caudate putamen (cpu) were measured. |
2021-08-17 |
2023-08-13 |
mouse |
| Ross van de Wetering, Susan Schen. Regional changes in ∆FosB expression in rat brain following MDMA self-administration predict increased sensitivity to effects of locally infused MDMA. Addiction biology. vol 25. issue 5. 2021-08-11. PMID:31373119. |
mdma pretreatment enhanced mdma-produced hyperactivity only when administered into the nucleus accumbens or the medial, but not the lateral, caudate-putamen, mirroring the ∆fosb results. |
2021-08-11 |
2023-08-13 |
rat |
| Magalie Lenoir, Amy K Starosciak, Jennifer Ledon, Caitlin Booth, Elena Zakharova, Dean Wade, Beatrice Vignoli, Sari Izenwasse. Sex differences in conditioned nicotine reward are age-specific. Pharmacology, biochemistry, and behavior. vol 132. 2021-07-27. PMID:25735492. |
there also were differences in nicotinic acetylcholinergic receptor binding in nucleus accumbens and caudate putamen in response to nicotine across age and sex. |
2021-07-27 |
2023-08-13 |
rat |
| Anil Joshi, Fanny Faivre, Susanne Eva la Fleur, Michel Barro. Midbrain and Lateral Nucleus Accumbens Dopamine Depletion Affects Free-choice High-fat high-sugar Diet Preference in Male Rats. Neuroscience. vol 467. 2021-07-12. PMID:34048800. |
to determine which of the midbrain dopamine projections may contribute to this effect, we next compared the impact of 6-ohda lesions of terminal fields, targeting the dorsal striatum, the lateral nucleus accumbens and the medial nucleus accumbens. |
2021-07-12 |
2023-08-13 |
rat |
| Caroline E Strong, Mohamed Kabba. Neural Mechanisms Underlying the Rewarding and Therapeutic Effects of Ketamine as a Treatment for Alcohol Use Disorder. Frontiers in behavioral neuroscience. vol 14. 2021-07-08. PMID:33362485. |
to do this, the focus will be on reward-related brain regions such as the nucleus accumbens (nac), dorsal striatum, prefrontal cortex (pfc), hippocampus, and ventral tegmental area (vta) to understand how acute vs. chronic exposure will alter reward signaling over time. |
2021-07-08 |
2023-08-13 |
human |
| Fabien Naneix, Kate Z Peters, Andrew M J Young, James E McCutcheo. Age-dependent effects of protein restriction on dopamine release. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32737419. |
in the present study, we investigated the impact of protein restriction either during adolescence or adulthood on the function of the mesolimbic (nucleus accumbens) and nigrostriatal (dorsal striatum) dopamine pathways using fast-scan cyclic voltammetry in rat brain slices. |
2021-06-23 |
2023-08-13 |
rat |
| Kaili Du, Zhuoyi Wang, Huimin Zhang, Yaofang Zhang, Hongliang Su, Zhiwen Wei, Chao Zhang, Keming Yun, Bin Con. Levo-tetrahydropalmatine attenuates the acquisition of fentanyl-induced conditioned place preference and the changes in ERK and CREB phosphorylation expression in mice. Neuroscience letters. vol 756. 2021-06-22. PMID:34029649. |
western blot assays were used to dissect the accompanying changes in the phosphorylation of extracellular signal-regulated kinase (erk) and camp response element binding protein (creb) in related brain regions, including the hippocampus (hip), caudate putamen (cpu), prefrontal cortex (pfc), and nucleus accumbens (nac), which may mediate the effects of l-thp on fentanyl-induced cpp. |
2021-06-22 |
2023-08-13 |
mouse |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Joseph R Driscoll, Tanya L Wallace, Kasra A Mansourian, William J Martin, Elyssa B Margoli. Differential Modulation of Ventral Tegmental Area Circuits by the Nociceptin/Orphanin FQ System. eNeuro. vol 7. issue 5. 2021-06-18. PMID:32747458. |
n/ofq and its receptor, nop, are enriched in dopaminergic pathways, and intra-ventricular agonist delivery decreases dopamine levels in the dorsal striatum, nucleus accumbens (nac), and ventral tegmental area (vta). |
2021-06-18 |
2023-08-13 |
rat |
| Thomas Contesse, Loïc Broussot, Hugo Fofo, Peter Vanhoutte, Sebastian P Fernandez, Jacques Bari. Dopamine and glutamate receptors control social stress-induced striatal ERK1/2 activation. Neuropharmacology. vol 190. 2021-06-09. PMID:33781778. |
the nucleus accumbens (nac) showed marked increases in perk1/2 following both acute and chronic social stress compared to the dorsal striatum. |
2021-06-09 |
2023-08-13 |
mouse |
| Milo Grotell, Bjørnar den Hollander, Aaro Jalkanen, Essi Törrönen, Jouni Ihalainen, Elena de Miguel, Mateusz Dudek, Mikko I Kettunen, Petri Hyytiä, Markus M Forsberg, Esko Kankuri, Esa R Korp. Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity. Frontiers in pharmacology. vol 12. 2021-05-18. PMID:33995109. |
these effects were most profound in brain regions which are known to have high dopamine and serotonin activities including hippocampus, nucleus accumbens and caudate-putamen. |
2021-05-18 |
2023-08-13 |
rat |
| Chiomah Ezeomah, Kathryn A Cunningham, Sonja J Stutz, Robert G Fox, Natalya Bukreyeva, Kelly T Dineley, Slobodan Paessler, Irma E Cisnero. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32165150. |
several innate immune markers, as well as opioid receptors (ors) and intracellular pattern recognition receptors (prrs), were interrogated within nodes of the neurocircuitry involved in oud processes, including the prefrontal cortex (pfc), nucleus accumbens (nac), caudate putamen (cpu), hippocampus (hip) and midbrain (mb). |
2021-04-27 |
2023-08-13 |
rat |
| Patricia Novaes Soares, Rosiane Aparecida Miranda, Iala Milene Bertasso, Carla Bruna Pietrobon, Vanessa Silva Tavares Rodrigues, Elaine de Oliveira, Alex Christian Manhães, Egberto Gaspar de Moura, Patricia Cristina Lisbo. Late effects of early weaning on food preference and the dopaminergic and endocannabinoid systems in male and female rats. Journal of developmental origins of health and disease. 2021-03-02. PMID:33650480. |
at pn180, ew males showed lower type 2 dopamine receptor (d2r) in the nucleus accumbens (nac) and dorsal striatum, while ew females had lower tyrosine hydroxylase in the ventral tegmental area and nac, d1r in the nac, and d2r in the prefrontal cortex. |
2021-03-02 |
2023-08-13 |
rat |
| Mei Huang, Wenqi He, Lakshmi Rajagopal, Andrea Kudwa, Dimitri E Grigoriadis, Herbert Y Meltze. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacology, biochemistry, and behavior. vol 190. 2021-01-07. PMID:32084491. |
we utilized microdialysis in awake, freely moving mice to determine the effect of nbi-98782, the active metabolite of valbenazine, alone, or in combination with several antipsychotic drugs (apds), to influence neurotransmitter efflux in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), hippocampus and nucleus accumbens (nac); we also compared it with tetrabenazine, the prototypical vmat2 inhibitor. |
2021-01-07 |
2023-08-13 |
mouse |
| Johnathan M Borland, Ellen Kim, Samuel P Swanson, Patrick E Rothwell, Paul G Mermelstein, Robert L Meise. Effect of Aggressive Experience in Female Syrian Hamsters on Glutamate Receptor Expression in the Nucleus Accumbens. Frontiers in behavioral neuroscience. vol 14. 2021-01-06. PMID:33328919. |
in the following study, using syrian hamsters as a well-validated and translational model of female aggression, we investigated the effects of aggressive experience on the expression of markers of postsynaptic structure (psd-95, caskin i) and excitatory synaptic transmission (glua1, glua2, glua4, nr2a, nr2b, mglur1a, and mglur5) in the nucleus accumbens (nac), caudate putamen and prefrontal cortex. |
2021-01-06 |
2023-08-13 |
Not clear |
| Gang Chen, Tao Li, Jing Xiao, Jing Wang, Qing Shang, Hongyan Qian, Chuchu Qiao, Ping Zhang, Teng Chen, Xinshe Li. Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization Through the GluN2B-PP2A-AKT Cascade in the Dorsal Striatum of Mice. Neurochemical research. vol 45. issue 4. 2020-12-11. PMID:31981057. |
in this study, we measured the level of phosphorylated (p-) glun2b (serine; ser 1303), pp2a/b (a regulatory subunit of pp2a), and pp2a/c (a catalytic subunit of pp2a) in different brain regions such as the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (ds), and hippocampus (hip). |
2020-12-11 |
2023-08-13 |
mouse |
| Hongliang Su, Tingting Sun, Xiao Wang, Yan Du, Na Zhao, Jie Zhu, Jiangwei Yan, Teng Chen, Keming Yu. Levo-tetrahydropalmatine attenuates methamphetamine reward behavior and the accompanying activation of ERK phosphorylation in mice. Neuroscience letters. vol 714. 2020-12-07. PMID:31398456. |
we then dissected the underlying molecular mechanisms of l-thp in modulating meth-induced cpp by evaluating accompanying changes in expression of phosphorylated extracellular signal-regulated kinase (p-erk) in reward-relevant brain regions, including nucleus accumbens (nac), prefrontal cortex (pfc), caudate putamen (cpu), and hippocampus (hip), which may mediate the effects of l-thp on meth-induced cpp. |
2020-12-07 |
2023-08-13 |
mouse |