| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaghayegh Navabpour, Kayla Farrell, Shannon E Kincaid, Nour Omar, Madeline Musaus, Yu Lin, Hehuang Xie, Timothy J Jarom. Monoubiquitination of histone H2B is a crucial regulator of the transcriptome during memory formation. Learning & memory (Cold Spring Harbor, N.Y.). vol 31. issue 3. 2024-04-08. PMID:38580378. |
here, we found that fear conditioning in male rats increased or decreased the expression of 86 genes in the hippocampus but, surprisingly, sirna-mediated knockdown of the h2bub ligase, |
2024-04-08 |
2024-04-10 |
rat |
| Wisteria Deng, Lauri Tuominen, Rachel Sussman, Logan Leathem, Louis N Vinke, Daphne J Hol. Changes in responses of the amygdala and hippocampus during fear conditioning are associated with persecutory beliefs. Scientific reports. vol 14. issue 1. 2024-04-08. PMID:38589562. |
changes in responses of the amygdala and hippocampus during fear conditioning are associated with persecutory beliefs. |
2024-04-08 |
2024-04-11 |
human |
| Callum M P Thomas, Mark E Bouton, John T Gree. Chemogenetic inhibition of the ventral hippocampus but not its direct projection to the prelimbic cortex attenuates context-specific operant responding. Frontiers in behavioral neuroscience. vol 18. 2024-02-22. PMID:38385002. |
in pavlovian fear conditioning the ventral hippocampus (vh) and its projection to the pl have been shown to be important in supporting the effects of context on learning. |
2024-02-22 |
2024-02-24 |
rat |
| Samantha L Plas, Tuğçe Tuna, Hugo Bayer, Vitor A L Juliano, Samantha O Sweck, Angel D Arellano Perez, James E Hassell, Stephen Mare. Neural circuits for the adaptive regulation of fear and extinction memory. Frontiers in behavioral neuroscience. vol 18. 2024-02-19. PMID:38370858. |
we will focus on neural circuits regulating the acquisition and extinction of pavlovian fear conditioning in rodent models, particularly the role of the medial prefrontal cortex and hippocampus in the contextual control of extinguished fear memories. |
2024-02-19 |
2024-02-21 |
Not clear |
| David V C Brito, Janina Kupke, Rostilav Sokolov, Sidney Cambridge, Martin Both, C Peter Bengtson, Andrei Rozov, Ana M M Oliveir. Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice. Molecular psychiatry. 2024-02-12. PMID:38347124. |
using a contextual fear conditioning paradigm, we found that low stimulus salience leads to monophasic npas4 expression, while highly salient learning induces a biphasic expression of npas4 in the hippocampus. |
2024-02-12 |
2024-02-15 |
mouse |
| Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. |
keratinocyte-derived cytokine in the hippocampus disrupts extinction of conditioned fear memory in tumor-bearing mice. |
2024-02-03 |
2024-02-06 |
mouse |
| Kayla Farrell, Aubrey Auerbach, Madeline Musaus, Shaghayegh Navabpour, Catherine Liu, Yu Lin, Hehuang Xie, Timothy J Jarom. Phosphorylation of RPT6 controls its ability to bind DNA and regulate gene expression in the hippocampus of male rats during memory formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-12-20. PMID:38124005. |
rna-sequencing following sirna-mediated knockdown of free rpt6 revealed 46 gene targets in the dorsal hippocampus of male rats following fear conditioning, where rpt6 was involved in transcriptional activation and repression. |
2023-12-20 |
2023-12-23 |
rat |
| Giovanna Traina, Jack A Tuszynsk. The Neurotransmission Basis of Post-Traumatic Stress Disorders by the Fear Conditioning Paradigm. International journal of molecular sciences. vol 24. issue 22. 2023-11-25. PMID:38003517. |
notably, in both humans and the rodent model, fear conditioning and context rely on dependent neurocircuitry in the amygdala and prefrontal cortex, cingulate gyrus, and hippocampus. |
2023-11-25 |
2023-11-28 |
Not clear |
| Miki Hashizume, Rina Ito, Rie Suge, Yasushi Hojo, Gen Murakami, Takayuki Murakosh. Correlation between cue fear memory retrieval and oscillatory network inhibition in the amygdala is disrupted by acute REM sleep deprivation. Neuroscience. 2023-11-09. PMID:37944580. |
in particular, fear memory after cued fear conditioning is strongly associated with the bla, whereas both the bla and hippocampus are essential for contextual fear memory formation. |
2023-11-09 |
2023-11-20 |
rat |
| Casagrande, R R Porto, J Haubrich, A Kautzmann, L de Oliveira Álvare. EMOTIONAL VALUE OF FEAR MEMORY AND THE ROLE OF THE VENTRAL HIPPOCAMPUS IN SYSTEMS CONSOLIDATION. Neuroscience. 2023-11-09. PMID:37944583. |
here, we investigatedhow distinct training intensities, with strong or weakcontextual fear conditioning, affect activation of the dorsal hippocampus (dhpc) and the vhpc.we foundthatthe time course of memory consolidation differs in fear memories of different training intensities in both the dhpc and vhpc.our results also indicate that memory generalization happens alongside greater activation of the vhpc, and these processes occur faster with stronger fear memories.the vhpc is required for the expression of remote fear memory andmay controlcontextual fear generalization,a view corroborated by the fact that inactivation of the vhpc suppresses generalized fear expression, making memory more precise again. |
2023-11-09 |
2023-11-20 |
Not clear |
| Sydney Weber Boutros, Benjamin Zimmerman, Sydney C Nagy, Vivek K Unni, Jacob Rabe. Cells with cFos and 53BP1 immunoreactivity in the CA1 region of the hippocampus from a young female apolipoprotein E4 (apoE) targeted replacement mouse 1.5 h after fear conditioning. Molecular psychiatry. vol 28. issue 8. 2023-11-01. PMID:37907758. |
cells with cfos and 53bp1 immunoreactivity in the ca1 region of the hippocampus from a young female apolipoprotein e4 (apoe) targeted replacement mouse 1.5 h after fear conditioning. |
2023-11-01 |
2023-11-08 |
mouse |
| Heather C Ratigan, Seetha Krishnan, Shai Smith, Mark E J Sheffiel. A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination. Nature communications. vol 14. issue 1. 2023-10-26. PMID:37875465. |
fear memories can be acquired through contextual fear conditioning (cfc) which relies on the hippocampus. |
2023-10-26 |
2023-11-08 |
mouse |
| Christine Stubbendorff, Ed Hale, Tobias Bast, Helen J Cassaday, Stephen J Martin, Sopapun Suwansawang, David M Halliday, Carl W Stevenso. Dopamine D1-like receptors modulate synchronized oscillations in the hippocampal-prefrontal-amygdala circuit in contextual fear. Scientific reports. vol 13. issue 1. 2023-10-17. PMID:37848657. |
contextual fear conditioning (cfc) is mediated by a neural circuit that includes the hippocampus, prefrontal cortex, and amygdala, but the neurophysiological mechanisms underlying the regulation of cfc by neuromodulators remain unclear. |
2023-10-17 |
2023-11-08 |
rat |
| Fernanda Nunes, Bruna Lotufo, Yury Velho Martins Lages, Sílvia Maisonnette, Thomas Krahe, Antonio Pedro Mello Cruz, J Landeira-Fernande. Increased hippocampal CREB phosphorylation after retrieval of remote contextual fear memories in Carioca High-conditioned Freezing rats. Neurobiology of learning and memory. 2023-09-20. PMID:37730100. |
specifically, we evaluated creb phosphorylation in the hippocampus of male carioca high- and low-conditioned freezing rats (chf and clf, respectively) upon re-exposure of animals to contextual cues associated to footshocks weeks after fear conditioning. |
2023-09-20 |
2023-10-07 |
rat |
| Meng-Die Li, Lu Wang, Yu-Qi Zheng, Dan-Hong Huang, Zhi-Xuan Xia, Jian-Min Liu, Dan Tian, Hui OuYang, Zi-Hao Wang, Zhen Huang, Xiao-Shan Lin, Xiao-Qian Zhu, Si-Ying Wang, Wei-Kai Chen, Shao-Wei Yang, Yue-Ling Zhao, Jia-An Liu, Zu-Cheng She. DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus. iScience. vol 26. issue 9. 2023-09-04. PMID:37664599. |
here, we found that the activity of dhhc2 was upregulated in the hippocampus after fear conditioning, and dhhc2 knockdown impaired fear induced memory and long-term potentiation (ltp). |
2023-09-04 |
2023-09-07 |
Not clear |
| Yi Li, Zhongmin Fan, Qi Jia, Hongwei Ma, You Wu, Xiaofeng Guo, Lixia Du, Xi Wang, Wugang Hou, Zongping Fang, Xijing Zhan. Chaperone-mediated autophagy (CMA) alleviates cognitive impairment by reducing neuronal death in sepsis-associated encephalopathy (SAE). Experimental neurology. 2023-04-21. PMID:37085004. |
although overexpression of lamp2a in neurons via adeno-associated virus injection in the hippocampus had little effect on the mortality of septic mice, this intervention significantly alleviated the memory impairments in contextual fear conditioning test, y-maze test and novel objective recognition test, and attenuated the neural death observed in sae mice. |
2023-04-21 |
2023-08-14 |
mouse |
| Sara Arciniegas Ruiz, Eliav Tikochinsky, Vardit Rubovitch, Chaim G Pick, Bernard Attal. Contextual fear response is modulated by M-type K+ channels and is associated with subtle structural changes of the axon initial segment in hippocampal GABAergic neurons. AIMS neuroscience. vol 10. issue 1. 2023-04-20. PMID:37077956. |
in addition, regarding the pivotal role of the hippocampus in contextual fear conditioning (cfc) and the involvement of the axon initial segment (ais) in neuronal plasticity, we investigated whether structural alterations of the ais in hippocampal neurons occurred during contextual fear memory acquisition and short-time extinction in mice in a behaviorally relevant context. |
2023-04-20 |
2023-08-14 |
mouse |
| Danya Abazari, Angela R Wild, Tian Qiu, Bryan C Dickinson, Shernaz X Bamj. Activity-dependent post-translational regulation of palmitoylating and depalmitoylating enzymes in the hippocampus. Journal of cell science. vol 136. issue 7. 2023-04-11. PMID:37039765. |
post-translational modifications of the zdhhc enzymes were also observed in the hippocampus following fear conditioning. |
2023-04-11 |
2023-08-14 |
Not clear |
| Heather Ratigan, Seetha Krishnan, Shai Smith, Mark Sheffiel. Direct Thalamic Inputs to Hippocampal CA1 Transmit a Signal That Suppresses Ongoing Contextual Fear Memory Retrieval. Research square. 2023-04-10. PMID:37034716. |
fear memories can be acquired through contextual fear conditioning (cfc) which relies on the hippocampus. |
2023-04-10 |
2023-08-14 |
Not clear |
| Heather C Ratigan, Seetha Krishnan, Shai Smith, Mark E J Sheffiel. Direct Thalamic Inputs to Hippocampal CA1 Transmit a Signal That Suppresses Ongoing Contextual Fear Memory Retrieval. bioRxiv : the preprint server for biology. 2023-04-10. PMID:37034812. |
fear memories can be acquired through contextual fear conditioning (cfc) which relies on the hippocampus. |
2023-04-10 |
2023-08-14 |
Not clear |