| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacobus C Buurstede, Eduardo H L Umeoka, Marcia Santos da Silva, Harm J Krugers, Marian Joëls, Onno C Meije. Application of a pharmacological transcriptome filter identifies a shortlist of mouse glucocorticoid receptor target genes associated with memory consolidation. Neuropharmacology. 2022-07-14. PMID:35835211. |
we here used a powerful paradigm to investigate the transcriptional effects of gr in the dorsal hippocampus of mice after training in an auditory fear conditioning task, aiming to identify a shortlist of gr target genes associated to memory consolidation. |
2022-07-14 |
2023-08-14 |
mouse |
| Emma N Fikse, Jianhua Zhang, Mritunjay Pandey, Glenda Smerin, Adam Awe, Nicole Lue, Claire Kittock, Weiping Chen, Yanqin Yang, Poorni Adikaram, Nirmal Jacob, Emily Greenfest-Allen, Rachel Thomas, Laura Bomeny, Xiaowen Wang, Yulong Li, William F Simond. Association of Mouse Vulnerability to Alzheimer's Disease Pathology with Mutations of Gnb5: A Modulator of G-protein Coupled Receptor Signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560642. |
for this project, we demonstrated through fear conditioning behavioral tasks involving hippocampus and amygdala function that learning and memory deficits existed in mice heterozygous for gnb5. |
2022-05-13 |
2023-08-13 |
mouse |
| Andie Dodge, Nicole Morrill, Edwin J Weeber, Kevin R Nas. Recovery of Angelman syndrome rat deficits with UBE3A protein supplementation. Molecular and cellular neurosciences. 2022-04-03. PMID:35367589. |
furthermore, injection of recombinant ube3a protein into the hippocampus of the as rat can rescue the associative learning and memory deficits seen in the fear conditioning task. |
2022-04-03 |
2023-08-13 |
rat |
| Julio David Vega-Torres, Perla Ontiveros-Angel, Esmeralda Terrones, Erwin C Stuffle, Sara Solak, Emma Tyner, Marie Oropeza, Ike Dela Peña, Andre Obenaus, Byron D Ford, Johnny D Figuero. Short-term exposure to an obesogenic diet during adolescence elicits anxiety-related behavior and neuroinflammation: modulatory effects of exogenous neuregulin-1. Translational psychiatry. vol 12. issue 1. 2022-02-27. PMID:35220393. |
we found that nrg1 administration reduced hippocampal volume (7%) and attenuated hippocampal-dependent cued fear conditioning in cd rats (56%). |
2022-02-27 |
2023-08-13 |
rat |
| Brianna Shultz, Abigail Farkash, Bailey Collins, Negin Mohammadmirzaei, Dayan Kno. Fear learning-induced changes in AMPAR and NMDAR expression in the fear circuit. Learning & memory (Cold Spring Harbor, N.Y.). vol 29. issue 3. 2022-02-16. PMID:35169047. |
nmda receptors (nmdars) and ampa receptors (ampars) in amygdala nuclei and the dorsal hippocampus (dhipp) are critical for fear conditioning. |
2022-02-16 |
2023-08-13 |
Not clear |
| Brianna Shultz, Abigail Farkash, Bailey Collins, Negin Mohammadmirzaei, Dayan Kno. Fear learning-induced changes in AMPAR and NMDAR expression in the fear circuit. Learning & memory (Cold Spring Harbor, N.Y.). vol 29. issue 3. 2022-02-16. PMID:35169047. |
whether similar changes occur in other nodes of the fear circuit (e.g., ventral hippocampus [vhipp]) or changes in nmdar expression in the fear circuit occur with fear conditioning have not been sufficiently examined. |
2022-02-16 |
2023-08-13 |
Not clear |
| Brianna Shultz, Abigail Farkash, Bailey Collins, Negin Mohammadmirzaei, Dayan Kno. Fear learning-induced changes in AMPAR and NMDAR expression in the fear circuit. Learning & memory (Cold Spring Harbor, N.Y.). vol 29. issue 3. 2022-02-16. PMID:35169047. |
long-term changes in glur1 and glur2 expression in the ventral hippocampus (vhipp) and anterior cingulate cortex (acc), enhanced nr2a expression in amygdala nuclei, and changes in the ratio of glur1/nr2a and glur2/nr2a in the dhipp was observed with fear conditioning. |
2022-02-16 |
2023-08-13 |
Not clear |
| Suzanne O Nolan, Samantha L Hodges, Matthew S Binder, Gregory D Smith, James T Okoh, Taylor S Jefferson, Brianna Escobar, Joaquin N Lug. Dietary rescue of adult behavioral deficits in the Fmr1 knockout mouse. PloS one. vol 17. issue 1. 2022-01-28. PMID:35089938. |
the post-weaning omega-3 diet reduced hippocampal expression of il-6 and this reduction of il-6 was significantly associated with diminished performance in the fear conditioning task. |
2022-01-28 |
2023-08-13 |
mouse |
| Annabel K Short, Viet Bui, Isabel C Zbukvic, Anthony J Hannan, Terence Y Pang, Jee Hyun Ki. Sex-dependent effects of chronic exercise on cognitive flexibility but not hippocampal Bdnf in aging mice. Neuronal signaling. vol 6. issue 1. 2022-01-17. PMID:35036000. |
the hippocampus is critical for cognitive flexibility involved with extinction and reinstatement of conditioned fear. |
2022-01-17 |
2023-08-13 |
mouse |
| Roya Malekloo, Setayesh Nematollahi, Abbas Ali Vafei, Ali Rashidy-Pou. Effects of different intensities of treadmill exercise on cued fear extinction failure, hippocampal BDNF decline, and Bax/Bcl-2 ratio alteration in chronic - morphine treated male rats. Behavioural brain research. 2022-01-06. PMID:34990697. |
subsequently, rats received a cued fear conditioning followed by four days of extinction training, and the expression of hippocampal bdnf and apoptotic proteins was determined. |
2022-01-06 |
2023-08-13 |
rat |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. |
2022-01-04 |
2023-08-13 |
rat |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
the hippocampus is an important part of the neural circuitry that controls fear conditioning and can also modulate prefrontal and striatal mechanisms, including dopamine signalling, which play a role in salience modulation. |
2022-01-04 |
2023-08-13 |
rat |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
consequently, hippocampal neural disinhibition may contribute to impairments in fear conditioning and salience modulation reported in schizophrenia. |
2022-01-04 |
2023-08-13 |
rat |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
therefore, we examined the effect of ventral hippocampus (vh) disinhibition in male rats on fear conditioning and salience modulation, as reflected by latent inhibition (li), in a conditioned emotional response procedure (cer). |
2022-01-04 |
2023-08-13 |
rat |
| Stuart A Williams, Miriam Gwilt, Rebecca Hock, Charlotte Taylor, Joanna Loayza, Carl W Stevenson, Helen J Cassaday, Tobias Bas. Hippocampal disinhibition reduces contextual and elemental fear conditioning while sparing the acquisition of latent inhibition. eNeuro. 2022-01-04. PMID:34980662. |
the disruption of fear conditioning resembles aversive conditioning deficits reported in schizophrenia and may reflect a disruption of neural processing both within the hippocampus and in projection sites of the hippocampus. |
2022-01-04 |
2023-08-13 |
rat |
| Anupratap Tomar, Thomas J McHug. The impact of stress on the hippocampal spatial code. Trends in neurosciences. 2021-12-17. PMID:34916083. |
we review hippocampal place cell studies that examine how spatial coding is affected by acute and chronic stress, as well as by stress accompanying fear conditioning. |
2021-12-17 |
2023-08-13 |
Not clear |
| Márcio Braga de Melo, Maria Gabriela Menezes Oliveira, Vanessa Manchim Favar. The dorsal subiculum is not necessary for step-through inhibitory avoidance acquisition and consolidation in rats. Behavioral neuroscience. vol 135. issue 6. 2021-12-07. PMID:34291967. |
the dorsal subiculum (dsub) has reciprocal connections with the dorsal hippocampus, and these regions play a role in spatial representation in contextual fear conditioning (cfc). |
2021-12-07 |
2023-08-13 |
rat |
| James Delorme, Lijing Wang, Femke Roig Kuhn, Varna Kodoth, Jingqun Ma, Jessy D Martinez, Frank Raven, Brandon A Toth, Vinodh Balendran, Alexis Vega Medina, Sha Jiang, Sara J Ato. Sleep loss drives acetylcholine- and somatostatin interneuron-mediated gating of hippocampal activity to inhibit memory consolidation. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 32. 2021-12-01. PMID:34344824. |
we find that ps6 is enhanced in dentate gyrus (dg) following single-trial contextual fear conditioning (cfc) but is reduced throughout the hippocampus after brief sleep deprivation (sd; which disrupts contextual fear memory [cfm] consolidation). |
2021-12-01 |
2023-08-13 |
mouse |
| Fu-Lian Huang, Fang Li, Wen-Juan Zhang, Song-Ji Li, Ze-Hua Yang, Tian-Lun Yang, Jun Qi, Qiong Duan, Chang-Qi L. Brd4 participates in epigenetic regulation of the extinction of remote auditory fear memory. Neurobiology of learning and memory. vol 179. 2021-11-29. PMID:33460788. |
auditory fear conditioning resulted in a biphasic brd4 activation in the anterior cingulate cortex (acc) and hippocampus of adult mice. |
2021-11-29 |
2023-08-13 |
mouse |
| Ross Minter, Katheleen J Gardine. Trisomy of Human Chromosome 21 Orthologs Mapping to Mouse Chromosome 10 Cause Age and Sex-Specific Learning Differences: Relevance to Down Syndrome. Genes. vol 12. issue 11. 2021-11-29. PMID:34828303. |
here, we have tested separate cohorts of female and male dp10 mice, at 3 and 9 months of age, in an open field elevated zero maze, rotarod, and balance beam, plus the learning and memory tasks, spontaneous alternation, puzzle box, double-h maze, context fear conditioning, and acoustic startle/prepulse inhibition, that depend upon the function of the prefrontal cortex, striatum, hippocampus, and cerebellum. |
2021-11-29 |
2023-08-13 |
mouse |