All Relations between hippocampus and fear conditioning paradigm

Publication Sentence Publish Date Extraction Date Species
Sean M Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R Seemiller, Molly A Bogue, Stephen C Grubb, Gary Peltz, Thomas J Goul. Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains. Frontiers in psychiatry. vol 12. 2021-11-05. PMID:34733190. we measured conditioned fear behavior and ache activity in the dorsal hippocampus, ventral hippocampus, and cerebellum. 2021-11-05 2023-08-13 mouse
Sean M Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R Seemiller, Molly A Bogue, Stephen C Grubb, Gary Peltz, Thomas J Goul. Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains. Frontiers in psychiatry. vol 12. 2021-11-05. PMID:34733190. there was an inverse correlation between fear conditioning outcomes and ache levels in the dorsal hippocampus. 2021-11-05 2023-08-13 mouse
Sean M Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R Seemiller, Molly A Bogue, Stephen C Grubb, Gary Peltz, Thomas J Goul. Genetic Differences in Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains. Frontiers in psychiatry. vol 12. 2021-11-05. PMID:34733190. in contrast, the ventral hippocampus and cerebellum ache levels were not correlated with fear conditioning outcomes. 2021-11-05 2023-08-13 mouse
Ryan T Stott, Oleg Kritsky, Li-Huei Tsa. Profiling DNA break sites and transcriptional changes in response to contextual fear learning. PloS one. vol 16. issue 7. 2021-11-02. PMID:34197463. here, following contextual fear conditioning (cfc) in mice, we profiled the locations of dsbs genome-wide in the medial prefrontal cortex and hippocampus using γh2ax chip-seq. 2021-11-02 2023-08-13 mouse
Jalina Graham, Alexa F D'Ambra, Se Jung Jung, Yusuke Teratani-Ota, Nina Vishwakarma, Rasika Venkatesh, Abhijna Parigi, Evan G Antzoulatos, Diasynou Fioravante, Brian J Wiltge. High-Frequency Stimulation of Ventral CA1 Neurons Reduces Amygdala Activity and Inhibits Fear. Frontiers in behavioral neuroscience. vol 15. 2021-10-29. PMID:33767614. therefore, despite clear differences between the dorsal and ventral hippocampus, ca1 neurons in each segment appear to make similar contributions to context fear conditioning. 2021-10-29 2023-08-13 Not clear
Wei-Guang Li, Yan-Jiao Wu, Xue Gu, Hui-Ran Fan, Qi Wang, Jia-Jie Zhu, Xin Yi, Qin Wang, Qin Jiang, Ying Li, Ti-Fei Yuan, Han Xu, Jiangteng Lu, Nan-Jie Xu, Michael Xi Zhu, Tian-Le X. Input associativity underlies fear memory renewal. National science review. vol 8. issue 9. 2021-10-26. PMID:34691732. here, using an auditory fear conditioning paradigm in mice, we show that fear renewal is determined by the associativity between convergent inputs from the auditory cortex (acx) and ventral hippocampus (vhpc) onto the lateral amygdala (la) that reactivate ensembles engaged during learning. 2021-10-26 2023-08-13 mouse
Vipan K Parihar, Munjal M Acharya, Dante E Roa, Omar Bosch, Lori-Ann Christie, Charles L Limol. Defining functional changes in the brain caused by targeted stereotaxic radiosurgery. Translational cancer research. vol 3. issue 2. 2021-10-21. PMID:24904783. while whole brain irradiation was found to elicit significant deficits in novel place recognition and fear conditioning, standard platforms for quantifying hippocampal and non-hippocampal decrements, irradiation targeted to both hippocampi was only found to elicit deficits in fear conditioning. 2021-10-21 2023-08-13 rat
Zhenfu Wen, Zhe Sage Chen, Mohammed R Mila. Fear extinction learning modulates large-scale brain connectivity. NeuroImage. vol 238. 2021-10-19. PMID:34126211. the field has focused on examining the role of various regions of the medial prefrontal cortex, insular cortex, hippocampus, and amygdala in conditioned fear and its extinction. 2021-10-19 2023-08-13 human
Xiu Yang, Xu Li, Le Liu, Yuan-Hao Chen, Yue You, Yin Gao, Yue-Ying Liu, Li Yang, Kun Tong, Di-Shi Chen, Jing-Ru Hao, Nan Sun, Zi-Ming Zhao, Can Ga. Transferrin-Pep63-liposomes accelerate the clearance of Aβ and rescue impaired synaptic plasticity in early Alzheimer's disease models. Cell death discovery. vol 7. issue 1. 2021-10-08. PMID:34548476. we discovered that administration of tf-pep63-lip could significantly reduce the aβ burden in the hippocampus, and improve cognitive deficits in 6-month-old app/ps1 mice in the morris-water maze task and fear-conditioning test with the combined effects of pa and pep63. 2021-10-08 2023-08-13 mouse
Victor Daniel Vasquez Matsuda, Martin Bustelo Tejada, Lívia Clemente Motta-Teixeira, Juliane Midori Ikebara, Débora Sterzeck Cardoso, Aline Vilar Machado-Nils, Vitor Yonamine Lee, Isabelle Diccini, Bruna Petrucelli Arruda, Pamela Pinheiro Martins, Natália Myuki Morales Dias, Rafaella Pinto Tessarotto, Reza Raeisossadati, Martin Bruno, Luiz Fernando Takase, Alexandre Hiroaki Kihara, Maria Inês Nogueira, Gilberto Fernando Xavier, Silvia Honda Takad. Impact of neonatal anoxia and hypothermic treatment on development and memory of rats. Experimental neurology. vol 340. 2021-09-27. PMID:33713657. the effects of th on both developmental features (somatic growth, maturation of physical characteristics and early neurological reflexes) and performance of behavioral tasks at adulthood (spatial reference and working memory, and fear conditioning) were investigated in association with the possible involvement of the epigenetic operator enhancer of zeste homolog 2 (ezh2), possibly related to long-lasting effects on hippocampal neurogenesis. 2021-09-27 2023-08-13 rat
Hieu Hoang Trung, Toru Yoshihara, Akito Nakao, Katsumi Hayashida, Yoshiki Hirata, Koumei Shirasuna, Mitsuru Kuwamura, Yuki Nakagawa, Takehito Kaneko, Yasuo Mori, Masahide Asano, Takashi Kuramot. Deficiency of the RIβ subunit of protein kinase A causes body tremor and impaired fear conditioning memory in rats. Scientific reports. vol 11. issue 1. 2021-09-23. PMID:33479380. mice lacking the riβ subunit exhibit normal long-term potentiation (ltp) in the schaffer collateral pathway of the hippocampus and normal behavior in the open-field and fear conditioning tests. 2021-09-23 2023-08-13 mouse
Lisa R Goldberg, Dana Zeid, Munir Gunes Kutlu, Robert D Cole, Valeria Lallai, Aswathy Sebastian, Istvan Albert, Christie D Fowler, Vinay Parikh, Thomas J Goul. Paternal nicotine enhances fear memory, reduces nicotine administration, and alters hippocampal genetic and neural function in offspring. Addiction biology. vol 26. issue 1. 2021-09-09. PMID:31782218. we tested the effects of chronic paternal nicotine exposure in c57bl6/j mice on fear conditioning in f1 and f2 offspring, as well as conditioned fear extinction and spontaneous recovery, nicotine self-administration, hippocampal cholinergic functioning, rna expression, and dna methylation in f1 offspring. 2021-09-09 2023-08-13 mouse
Maria Gomis-González, Lorena Galera-López, Marc Ten-Blanco, Arnau Busquets-Garcia, Thomas Cox, Rafael Maldonado, Andrés Ozait. Protein Kinase C-Gamma Knockout Mice Show Impaired Hippocampal Short-Term Memory While Preserved Long-Term Memory. Molecular neurobiology. vol 58. issue 2. 2021-09-01. PMID:32996086. in the hippocampus, pkc-gamma was found to translocate to the membrane after auditory trace, but not after delay fear conditioning. 2021-09-01 2023-08-13 mouse
Min Soo Kang, Jin-Hee Ha. Optogenetic inhibition of medial entorhinal cortex inputs to the hippocampus during a short period of time right after learning disrupts contextual fear memory formation. Molecular brain. vol 14. issue 1. 2021-09-01. PMID:33407673. to examine this possibility, we optogenetically inhibited axons and terminals originating from bilateral dorsal mec excitatory neurons in the dorsal hippocampus for 5 min right after contextual fear conditioning (cfc). 2021-09-01 2023-08-13 mouse
Thomas K Pak, Calvin S Carter, Qihong Zhang, Sunny C Huang, Charles Searby, Ying Hsu, Rebecca J Taugher, Tim Vogel, Christopher C Cychosz, Rachel Genova, Nina N Moreira, Hanna Stevens, John A Wemmie, Andrew A Pieper, Kai Wang, Val C Sheffiel. A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. PLoS genetics. vol 17. issue 4. 2021-08-25. PMID:33886537. two-week treatment with lithium chloride partially restores the proliferation of hippocampal neurons which leads to a rescue of context fear conditioning. 2021-08-25 2023-08-13 mouse
Thomas K Pak, Calvin S Carter, Qihong Zhang, Sunny C Huang, Charles Searby, Ying Hsu, Rebecca J Taugher, Tim Vogel, Christopher C Cychosz, Rachel Genova, Nina N Moreira, Hanna Stevens, John A Wemmie, Andrew A Pieper, Kai Wang, Val C Sheffiel. A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. PLoS genetics. vol 17. issue 4. 2021-08-25. PMID:33886537. overall, our results identify a novel role of cilia genes in hippocampal neurogenesis and long-term context fear conditioning. 2021-08-25 2023-08-13 mouse
Smitha Karunakara. Early β adrenoceptor dependent time window for fear memory persistence in APPswe/PS1dE9 mice. Scientific reports. vol 11. issue 1. 2021-08-17. PMID:33441593. intra-ca1 infusion of isoproterenol hydrochloride, the β-adrenoceptor agonist, to the ventral hippocampus of appswe/ps1de9 mice immediately before fear conditioning restored long-term contextual fear memory. 2021-08-17 2023-08-13 mouse
Asmae Lguensat, Christian Montanari, Cassandre Vielle, Mohamed Bennis, Saadia Ba-M'hamed, Christelle Baunez, René Garci. Repeated cocaine exposure prior to fear conditioning induces persistency of PTSD-like symptoms and enhancement of hippocampal and amygdala cell density in male rats. Brain structure & function. vol 226. issue 7. 2021-08-11. PMID:34195855. repeated cocaine exposure prior to fear conditioning induces persistency of ptsd-like symptoms and enhancement of hippocampal and amygdala cell density in male rats. 2021-08-11 2023-08-13 rat
Robert H Oakley, Shannon D Whirledge, Maria G Petrillo, Natallia V Riddick, Xiaojiang Xu, Sheryl S Moy, John A Cidlowsk. Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus. Neurobiology of stress. vol 15. 2021-08-10. PMID:34368410. mice lacking mr alone or both gr and mr in the hippocampus exhibited altered expression of multiple ca2-specific neuronal markers and enhanced cue-dependent learning in a conditioned fear test. 2021-08-10 2023-08-13 mouse
Yanmei Chen, Na Kang, Jingsheng Gu, Boling Chu, Lilu Luo, Yingjie An, Fengyuan Yang, Jun Cao, Jichuan Zhan. Inactivation of endopeduncular nucleus impaired fear conditioning and hippocampal synaptic plasticity in rats. Neurobiology of learning and memory. vol 173. 2021-07-27. PMID:32246991. inactivation of endopeduncular nucleus impaired fear conditioning and hippocampal synaptic plasticity in rats. 2021-07-27 2023-08-13 rat