| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jacob H Wilmot, Cassiano R A F Diniz, Ana P Crestani, Kyle R Puhger, Jacob Roshgadol, Lin Tian, Brian Joseph Wiltge. Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus. eLife. vol 12. 2024-04-09. PMID:38592773. |
finally, we show that hippocampal dopamine is important for trace fear memory formation, while norepinephrine is not. |
2024-04-09 |
2024-04-11 |
mouse |
| Hanna M Molla, Anabel M M Miguelez Fernández, Kuei Y Tsen. Late-adolescent onset of prefrontal endocannabinoid control of hippocampal and amygdalar inputs and its impact on trace-fear conditioning behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-12. PMID:38467844. |
collectively, these results indicate a protracted recruitment of pfc endocannabinoid signaling, which becomes online in late adolescence/young adulthood as revealed by its impact on hippocampal and amygdalar-evoked local field potential responses and trace fear memory behavior. |
2024-03-12 |
2024-03-14 |
rat |
| Ethan J Goodman, Rebecca G Biltz, Jonathan M Packer, Damon J DiSabato, Samuel P Swanson, Braeden Oliver, Ning Quan, John F Sheridan, Jonathan P Godbou. Enhanced fear memory after social defeat in mice is dependent on interleukin-1 receptor signaling in glutamatergic neurons. Molecular psychiatry. 2024-03-08. PMID:38459193. |
nonetheless, neuronal reactivity (pcreb) and il-1β rna expression in the hippocampus and enhanced fear memory after rsd were microglial-independent. |
2024-03-08 |
2024-03-11 |
mouse |
| Hiroaki Hori, Hotaka Fukushima, Taikai Nagayoshi, Rie Ishikawa, Min Zhuo, Fuyuko Yoshida, Hiroshi Kunugi, Kenichi Okamoto, Yoshiharu Kim, Satoshi Kid. Fear memory regulation by the cAMP signaling pathway as an index of reexperiencing symptoms in posttraumatic stress disorder. Molecular psychiatry. 2024-02-27. PMID:38409596. |
in line with these observations, integrative mouse and human transcriptome analysis revealed the reduced mrna expression of phosphodiesterase 4b (pde4b), an enzyme that degrades camp, in the peripheral blood of ptsd patients showing more severe reexperiencing symptoms and the mouse hippocampus after fear memory retrieval. |
2024-02-27 |
2024-03-02 |
mouse |
| Yujun Wen, Jinhong Jiang, Feng Zhai, Fangfang Fan, Jun L. Sleep-wake dependent hippocampal regulation of fear memory. Sleep medicine. vol 115. 2024-02-17. PMID:38367358. |
sleep-wake dependent hippocampal regulation of fear memory. |
2024-02-17 |
2024-02-20 |
Not clear |
| Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. |
keratinocyte-derived cytokine in the hippocampus disrupts extinction of conditioned fear memory in tumor-bearing mice. |
2024-02-03 |
2024-02-06 |
mouse |
| Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. |
microinjection of kc into the hippocampus, but not into the amygdala, increased fear memory in normal mice. |
2024-02-03 |
2024-02-06 |
mouse |
| Hiroko Ikeda, Aimi Yamagishi, Naomi Yonemochi, Shogo Yamamoto, Takatsune Shimizu, Akihiro Muto, John L Waddington, Junzo Kame. Keratinocyte-Derived Cytokine in the Hippocampus Disrupts Extinction of Conditioned Fear Memory in Tumor-Bearing Mice. Molecular neurobiology. 2024-02-03. PMID:38308664. |
these findings indicate that tb mice show an increase in serum cytokines, including il-1β, that increases kc production in microglia of the hippocampus, which then disrupts extinction of fear memory. |
2024-02-03 |
2024-02-06 |
mouse |
| Alfredo Zuniga, Jiawei Han, Isaac Miller-Crews, Laura A Agee, Hans A Hofmann, Michael R Dre. Extinction Training Suppresses Activity of Fear Memory Ensembles Across the Hippocampus and Alters Transcriptomes of Fear-Encoding Cells. bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260411. |
extinction training suppresses activity of fear memory ensembles across the hippocampus and alters transcriptomes of fear-encoding cells. |
2024-01-23 |
2024-01-25 |
Not clear |
| Bart C J Dirven, Lennart van Melis, Teya Daneva, Lieke Dillen, Judith R Homberg, Tamas Kozicz, Marloes J A G Hencken. Hippocampal trauma memory processing conveying susceptibility to traumatic stress. Neuroscience. 2024-01-14. PMID:38220126. |
three weeks post-learning, mice were re-exposed to the conditioning context to induce remote fear memory recall, and associated hippocampal neuronal activity was assessed. |
2024-01-14 |
2024-01-17 |
mouse |
| Bart C J Dirven, Lennart van Melis, Teya Daneva, Lieke Dillen, Judith R Homberg, Tamas Kozicz, Marloes J A G Hencken. Hippocampal trauma memory processing conveying susceptibility to traumatic stress. Neuroscience. 2024-01-14. PMID:38220126. |
while no differences in the size of the hippocampal neuronal ensemble activated during fear learning were observed between groups, susceptible mice displayed a smaller ensemble activated upon remote fear memory recall in the ventral ca1, higher regional hippocampal pv |
2024-01-14 |
2024-01-17 |
mouse |
| Razieh Hajisoltani, Gholam Hossein Meftah. Epinephrine injected into the basolateral amygdala affects anxiety-like behavior and memory performance in stressed rats. Neuroscience letters. 2023-12-12. PMID:38086522. |
this study aimed to investigate how the epinephrine in the bla affects hippocampal fear memory, anxiety, and plasticity in control and stressed rats. |
2023-12-12 |
2023-12-17 |
rat |
| Yue Teng, JiaYao Niu, Yang Liu, Han Wang, JinHong Chen, YuJia Kong, Ling Wang, Bo Lian, WeiWeng Wang, HongWei Sun, KuiTao Yu. Ketamine alleviates fear memory and spatial cognition deficits in a PTSD rat model via the BDNF signaling pathway of the hippocampus and amygdala. Behavioural brain research. 2023-12-04. PMID:38048914. |
ketamine alleviates fear memory and spatial cognition deficits in a ptsd rat model via the bdnf signaling pathway of the hippocampus and amygdala. |
2023-12-04 |
2023-12-10 |
rat |
| Miki Hashizume, Rina Ito, Rie Suge, Yasushi Hojo, Gen Murakami, Takayuki Murakosh. Correlation between cue fear memory retrieval and oscillatory network inhibition in the amygdala is disrupted by acute REM sleep deprivation. Neuroscience. 2023-11-09. PMID:37944580. |
in particular, fear memory after cued fear conditioning is strongly associated with the bla, whereas both the bla and hippocampus are essential for contextual fear memory formation. |
2023-11-09 |
2023-11-20 |
rat |
| Casagrande, R R Porto, J Haubrich, A Kautzmann, L de Oliveira Álvare. EMOTIONAL VALUE OF FEAR MEMORY AND THE ROLE OF THE VENTRAL HIPPOCAMPUS IN SYSTEMS CONSOLIDATION. Neuroscience. 2023-11-09. PMID:37944583. |
emotional value of fear memory and the role of the ventral hippocampus in systems consolidation. |
2023-11-09 |
2023-11-20 |
Not clear |
| Casagrande, R R Porto, J Haubrich, A Kautzmann, L de Oliveira Álvare. EMOTIONAL VALUE OF FEAR MEMORY AND THE ROLE OF THE VENTRAL HIPPOCAMPUS IN SYSTEMS CONSOLIDATION. Neuroscience. 2023-11-09. PMID:37944583. |
here, we investigatedhow distinct training intensities, with strong or weakcontextual fear conditioning, affect activation of the dorsal hippocampus (dhpc) and the vhpc.we foundthatthe time course of memory consolidation differs in fear memories of different training intensities in both the dhpc and vhpc.our results also indicate that memory generalization happens alongside greater activation of the vhpc, and these processes occur faster with stronger fear memories.the vhpc is required for the expression of remote fear memory andmay controlcontextual fear generalization,a view corroborated by the fact that inactivation of the vhpc suppresses generalized fear expression, making memory more precise again. |
2023-11-09 |
2023-11-20 |
Not clear |
| Eduarda G Nachtigall, Jociane de C Myskiw, Ivan Izquierdo, Cristiane R G Furin. Cellular mechanisms of contextual fear memory reconsolidation: Role of hippocampal SFKs, TrkB receptors and GluN2B-containing NMDA receptors. Psychopharmacology. 2023-09-12. PMID:37700085. |
although the molecular mechanisms that mediate fear memory reconsolidation are not entirely known, so here we investigated the molecular mechanisms in the hippocampus involved in contextual fear conditioning memory (cfc) reconsolidation in male wistar rats. |
2023-09-12 |
2023-10-07 |
rat |
| Yanan Wu, Kaiyi Zhou, Baiyang Liu, Jindong Xu, Liming Lei, Jiaqi Hu, Xiao Cheng, Feng Zhong, Sheng Wan. Glial Activation, Mitochondrial Imbalance, and Akt/mTOR Signaling May Be Potential Mechanisms of Cognitive Impairment in Heart Failure Mice. Neurotoxicity research. 2023-09-05. PMID:37668877. |
hf group cued fear memory, spatial memory, and learning impairment, accompanied by activation of glial cells (astrocytes, microglia, and oligodendrocytes) in the hippocampus. |
2023-09-05 |
2023-09-07 |
mouse |
| Meng-Die Li, Lu Wang, Yu-Qi Zheng, Dan-Hong Huang, Zhi-Xuan Xia, Jian-Min Liu, Dan Tian, Hui OuYang, Zi-Hao Wang, Zhen Huang, Xiao-Shan Lin, Xiao-Qian Zhu, Si-Ying Wang, Wei-Kai Chen, Shao-Wei Yang, Yue-Ling Zhao, Jia-An Liu, Zu-Cheng She. DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus. iScience. vol 26. issue 9. 2023-09-04. PMID:37664599. |
dhhc2 regulates fear memory formation, ltp, and akap150 signaling in the hippocampus. |
2023-09-04 |
2023-09-07 |
Not clear |
| Shaojie Yang, Guoqi Zh. Phytotherapy of abnormality of fear memory: A narrative review of mechanisms. Fitoterapia. 2023-07-23. PMID:37482307. |
it is generally believed that in post-traumatic stress disorder (ptsd), the high expression of fear memory is mainly determined by amygdala hyperactivity and hippocampus hypoactivity. |
2023-07-23 |
2023-08-14 |
Not clear |