| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
these results imply, that the ghs-r1a antagonist/jmv2959 might reduce/prevent some of the memory-linked molecular changes elicited by methamphetamine addiction within brain structures associated with memory (hipp), reward (nac), and motivation (mpfc), which may contribute to the previously observed significant jmv2959-induced reduction of the methamphetamine self-administration and drug-seeking behavior in the same animals. |
2023-03-04 |
2023-03-06 |
rat |
| Shole Jamali, Mohsen Parto Dezfouli, AmirAli Kalbasi, Mohammad Reza Daliri, Abbas Haghparas. Selective Modulation of Hippocampal Theta Oscillations in Response to Morphine versus Natural Reward. Brain sciences vol 13 issue 2 2023 36831866 |
selective modulation of hippocampal theta oscillations in response to morphine versus natural reward. |
2023-02-25 |
2023-03-06 |
rat |
| Li-Tian Yin, Rui-Rui Feng, Xiao-Yan Xie, Xiao-Rong Yang, Zhuan-Fang Yang, Jia-Jia Hu, Shu-Fen Wu, Ce Zhan. Matrix metalloproteinase-9 overexpression in the hippocampus reduces alcohol-induced conditioned-place preference by regulating synaptic plasticity in mice. Behavioural brain research vol issue 2023 36746309 |
using recombinant adeno-associated viruses to overexpress mmp-9 in the hippocampus, we investigated the nmdar, psd-95, and cellular cytoskeleton proteins f-actin/g-actin in the modulation of alcohol reward behavior in mice exposed to cpp. |
2023-02-06 |
2023-03-06 |
mouse |
| Li-Tian Yin, Rui-Rui Feng, Xiao-Yan Xie, Xiao-Rong Yang, Zhuan-Fang Yang, Jia-Jia Hu, Shu-Fen Wu, Ce Zhan. Matrix metalloproteinase-9 overexpression in the hippocampus reduces alcohol-induced conditioned-place preference by regulating synaptic plasticity in mice. Behavioural brain research vol issue 2023 36746309 |
we found that hippocampal infusions of mmp-9 decreased alcohol-induced place preference suggesting a reduction in alcohol reward. |
2023-02-06 |
2023-03-06 |
mouse |
| Hartej Gill, Roger S McIntyre, Colin Hawco, Nelson B Rodrigues, Barjot Gill, Joshua D DiVincenzo, Jonathan M Lieberman, C\\xc3\\xa9Ann A Marks, Danielle S Cha, Orly Lipsitz, Hana Nazal, Ashitija Jasrai, Joshua D Rosenblat, Rodrigo B Mansu. Evaluating the neural substrates of effort-expenditure for reward in adults with major depressive disorder and obesity. Psychiatry research. Neuroimaging vol 329 issue 2023 36708594 |
we evaluated the association between effort-expenditure for monetary reward and neural activation in regions associated with reward-based decision making (i.e., the caudate nucleus, anterior cingulate cortex (acc) and hippocampus) in people with mdd and obesity comorbidity. |
2023-01-28 |
2023-01-31 |
human |
| Hartej Gill, Roger S McIntyre, Colin Hawco, Nelson B Rodrigues, Barjot Gill, Joshua D DiVincenzo, Jonathan M Lieberman, C\\xc3\\xa9Ann A Marks, Danielle S Cha, Orly Lipsitz, Hana Nazal, Ashitija Jasrai, Joshua D Rosenblat, Rodrigo B Mansu. Evaluating the neural substrates of effort-expenditure for reward in adults with major depressive disorder and obesity. Psychiatry research. Neuroimaging vol 329 issue 2023 36708594 |
we observed no change in activation of the caudate nucleus, acc or hippocampus in participants with increased bmi when contrasting the high effort > low effort reward magnitude condition for the eefrt. |
2023-01-28 |
2023-01-31 |
human |
| Shaoqiang Han, Ruiping Zheng, Shuying Li, Bingqian Zhou, Yu Jiang, Keke Fang, Yarui Wei, Baohong Wen, Jianyue Pang, Hengfen Li, Yong Zhang, Yuan Chen, Jingliang Chen. Altered structural covariance network of nucleus accumbens is modulated by illness duration and severity of symptom in depression. Journal of affective disorders vol 324 issue 2023 36608848 |
patients with depression exhibited altered structural covariance of nacc connected to key brain regions in reward system including the medial orbitofrontal cortex, amygdala, insula, parahippocampa gyrus, precuneus, thalamus, hippocampus and cerebellum. |
2023-01-07 |
2023-01-30 |
human |
| Kyrsten Kawazoe, Ryan McGlynn, Wilder Felix, Raquel Sevilla, Siyang Liao, Praveen Kulkarni, Craig F Ferri. Dose-dependent effects of esketamine on brain activity in awake mice: A BOLD phMRI study. Pharmacology research & perspectives vol 10 issue 6 2022 36504448 |
it was hypothesized the prefrontal cortex, hippocampus, and brain areas associated with reward and motivation would show a dose-dependent increase in brain activity. |
2022-12-12 |
2023-01-30 |
mouse |
| Robin Hellerstedt, Deborah Talm. Reward does not modulate forgetting in free recall tests. Learning & memory (Cold Spring Harbor, N.Y.) vol 29 issue 12 2022 36446602 |
reward is thought to attenuate forgetting through the automatic effect of dopamine on hippocampal memory traces. |
2022-11-29 |
2023-01-30 |
human |
| Yanjun Sun, Lisa M Giocom. Neural circuit dynamics of drug-context associative learning in the mouse hippocampus. Nature communications vol 13 issue 1 2022 36344498 |
using longitudinal calcium imaging in freely behaving mice, we find that unlike the associative learning of natural reward, drug-context associations for psychostimulants and opioids are encoded in a specific subset of hippocampal neurons. |
2022-11-07 |
2023-01-30 |
mouse |
| Seetha Krishnan, Chad Heer, Chery Cherian, Mark E J Sheffiel. Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal. Nature communications vol 13 issue 1 2022 36333323 |
hippocampal place cells support reward-related spatial memories by forming a cognitive map that over-represents reward locations. |
2022-11-05 |
2023-01-30 |
mouse |
| Seetha Krishnan, Chad Heer, Chery Cherian, Mark E J Sheffiel. Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal. Nature communications vol 13 issue 1 2022 36333323 |
thus, internal states of high reward expectation enhance encoding of spatial memories by reinforcing hippocampal cognitive maps associated with reward. |
2022-11-05 |
2023-01-30 |
mouse |
| William C Griffin, Marcelo F Lopez, John J Woodward, Howard C Becke. Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice. Alcohol (Fayetteville, N.Y.) vol issue 2022 36328184 |
facilitated by its connectivity with other parts of the brain such as the nucleus accumbens (nac), the ventral hippocampus (vhc) supports many behaviors, including those related to reward seeking and addiction. |
2022-11-03 |
2023-01-30 |
mouse |
| Johannes B Mahr, Bob Fische. Internally Triggered Experiences of Hedonic Valence in Nonhuman Animals: Cognitive and Welfare Considerations. Perspectives on psychological science : a journal of the Association for Psychological Science vol issue 2022 36288434 |
these hippocampal activations coordinate with neural reward and fear centers as well as sensory and cortical areas in ways that are associated with conscious episodic mental imagery in humans. |
2022-10-26 |
2023-01-30 |
rat |
| Ali Veisi, Hossein Khaleghzadeh-Ahangar, Mojdeh Fattahi, Abbas Haghparas. The Role of Orexin-1 Receptors Within the Hippocampal CA1 Area in the Extinction and Reinstatement of Methamphetamine-Seeking Behaviors. Neurochemical research vol issue 2022 36284025 |
the orexin system is highly implicated in processing reward and addiction through connections with critical areas such as the hippocampus. |
2022-10-25 |
2023-01-30 |
rat |
| Ashley J McFalls, Christopher Jenney, Rachel S Stanford, Emma Woodward, Andras Hajnal, Patricia S Grigson, Kent E Vran. Greater Avoidance of a Saccharin Cue Paired with Passive Delivery of Heroin is Associated with a Select Increase in Expression of CRFR2 and CRFbp in the Hippocampus in Rats. Brain research bulletin vol issue 2022 36228871 |
in a rodent model of self-administration and reward devaluation, we previously showed that animals that suppress intake of a drug-paired saccharin cue show greater addiction-like behaviors, as well as increased gene-expression of elements of the corticotropin releasing factor (crf) pathway in the prefrontal cortex (mpfc), hippocampus (hipp), and ventral tegmental area (vta). |
2022-10-13 |
2023-01-30 |
rat |
| Edmund T Rolls, Sylvia Wirth, Gustavo Deco, Chu-Chung Huang, Jianfeng Fen. The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation. Human brain mapping vol issue 2022 36178249 |
this connectivity implicates it in hippocampal episodic memory, providing routes for "what," reward and semantic schema-related information to access the hippocampus. |
2022-09-30 |
2023-01-30 |
human |
| Edmund T Rolls, Sylvia Wirth, Gustavo Deco, Chu-Chung Huang, Jianfeng Fen. The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation. Human brain mapping vol issue 2022 36178249 |
these connectivities provide important routes for "what," reward, and "where" scene-related information for human hippocampal episodic memory and navigation. |
2022-09-30 |
2023-01-30 |
human |
| Dawei Miao, Xiaoguang Zhou, Xiaoyuan Wu, Chengdong Chen, Le Tia. Hippocampal morphological atrophy and distinct patterns of structural covariance network in Alzheimer's disease and mild cognitive impairment. Frontiers in psychology vol 13 issue 2022 36160522 |
in ad, the hippocampus further exhibited increased structural covariance connected to reward related brain regions, including the anterior cingulate cortex, the putamen, the caudate, and the insula compared with hcs. |
2022-09-26 |
2023-01-30 |
Not clear |
| Marques Jackson, Brittany L Foret, Jane Fontenot, Dana Hasselschwert, Josh Smith, Emily Romero, Karen M\\xc3\\xbcller Smit. Molecular examination of the endogenous opioid system in rhesus macaque monkeys with self-injurious behavior. Journal of neuroscience research vol issue 2022 36131680 |
the brain regions examined are linked to reward reinforcement and stress adaptation including the hypothalamus, orbital frontal cortex, nucleus accumbens, hippocampus, caudate, and the amygdala. |
2022-09-22 |
2023-01-30 |
human |