Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Mona M Garvert, Tankred Saanum, Eric Schulz, Nicolas W Schuck, Christian F Doelle. Hippocampal spatio-predictive cognitive maps adaptively guide reward generalization. Nature neuroscience. 2023-04-03. PMID:37012381. |
hippocampal spatio-predictive cognitive maps adaptively guide reward generalization. |
2023-04-03 |
2023-08-14 |
human |
Huaigui Liu, Wei Li, Nana Liu, Jie Tang, Lixin Sun, Jiayuan Xu, Yuan Ji, Yingying Xie, Hao Ding, Zhaoxiang Ye, Chunshui Yu, Wen Qi. Structural covariances of prefrontal subregions selectively associate with dopamine-related gene coexpression and schizophrenia. Cerebral cortex (New York, N.Y. : 1991). 2023-03-19. PMID:36935097. |
moreover, based on a schizophrenia postmortem expression dataset, we found that the da genes coexpression of schizophrenia was significantly reduced between the middle frontal gyrus and hippocampus, in which 21 da genes showed significantly unsynchronized expression changes, and the 21 genes' brain expression were enriched in brain activity invoked by working memory, reward, speech production, and episodic memory. |
2023-03-19 |
2023-08-14 |
human |
Max V McDermott, Akila Ram, Matthew T Mattoon, Emmaline E Haderlie, Megan C Raddatz, Madi K Thomason, Erin N Bobec. A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice. Pharmacology, biochemistry, and behavior. 2023-03-18. PMID:36933620. |
we first mapped the distribution of gpr171 and prosaas throughout the reward circuit of the brain using immunohistochemistry and showed that gpr171 and prosaas are localized in the hippocampus, basolateral amygdala, nucleus accumbens, prefrontal cortex. |
2023-03-18 |
2023-08-14 |
mouse |
Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
these results imply, that the ghs-r1a antagonist/jmv2959 might reduce/prevent some of the memory-linked molecular changes elicited by methamphetamine addiction within brain structures associated with memory (hipp), reward (nac), and motivation (mpfc), which may contribute to the previously observed significant jmv2959-induced reduction of the methamphetamine self-administration and drug-seeking behavior in the same animals. |
2023-03-04 |
2023-08-14 |
rat |
Shole Jamali, Mohsen Parto Dezfouli, AmirAli Kalbasi, Mohammad Reza Daliri, Abbas Haghparas. Selective Modulation of Hippocampal Theta Oscillations in Response to Morphine versus Natural Reward. Brain sciences. vol 13. issue 2. 2023-02-25. PMID:36831866. |
selective modulation of hippocampal theta oscillations in response to morphine versus natural reward. |
2023-02-25 |
2023-08-14 |
rat |
Li-Tian Yin, Rui-Rui Feng, Xiao-Yan Xie, Xiao-Rong Yang, Zhuan-Fang Yang, Jia-Jia Hu, Shu-Fen Wu, Ce Zhan. Matrix metalloproteinase-9 overexpression in the hippocampus reduces alcohol-induced conditioned-place preference by regulating synaptic plasticity in mice. Behavioural brain research. 2023-02-06. PMID:36746309. |
using recombinant adeno-associated viruses to overexpress mmp-9 in the hippocampus, we investigated the nmdar, psd-95, and cellular cytoskeleton proteins f-actin/g-actin in the modulation of alcohol reward behavior in mice exposed to cpp. |
2023-02-06 |
2023-08-14 |
mouse |
Li-Tian Yin, Rui-Rui Feng, Xiao-Yan Xie, Xiao-Rong Yang, Zhuan-Fang Yang, Jia-Jia Hu, Shu-Fen Wu, Ce Zhan. Matrix metalloproteinase-9 overexpression in the hippocampus reduces alcohol-induced conditioned-place preference by regulating synaptic plasticity in mice. Behavioural brain research. 2023-02-06. PMID:36746309. |
we found that hippocampal infusions of mmp-9 decreased alcohol-induced place preference suggesting a reduction in alcohol reward. |
2023-02-06 |
2023-08-14 |
mouse |
Hartej Gill, Roger S McIntyre, Colin Hawco, Nelson B Rodrigues, Barjot Gill, Joshua D DiVincenzo, Jonathan M Lieberman, CéAnn A Marks, Danielle S Cha, Orly Lipsitz, Hana Nazal, Ashitija Jasrai, Joshua D Rosenblat, Rodrigo B Mansu. Evaluating the neural substrates of effort-expenditure for reward in adults with major depressive disorder and obesity. Psychiatry research. Neuroimaging. vol 329. 2023-01-28. PMID:36708594. |
we evaluated the association between effort-expenditure for monetary reward and neural activation in regions associated with reward-based decision making (i.e., the caudate nucleus, anterior cingulate cortex (acc) and hippocampus) in people with mdd and obesity comorbidity. |
2023-01-28 |
2023-08-14 |
human |
Hartej Gill, Roger S McIntyre, Colin Hawco, Nelson B Rodrigues, Barjot Gill, Joshua D DiVincenzo, Jonathan M Lieberman, CéAnn A Marks, Danielle S Cha, Orly Lipsitz, Hana Nazal, Ashitija Jasrai, Joshua D Rosenblat, Rodrigo B Mansu. Evaluating the neural substrates of effort-expenditure for reward in adults with major depressive disorder and obesity. Psychiatry research. Neuroimaging. vol 329. 2023-01-28. PMID:36708594. |
we observed no change in activation of the caudate nucleus, acc or hippocampus in participants with increased bmi when contrasting the high effort > low effort reward magnitude condition for the eefrt. |
2023-01-28 |
2023-08-14 |
human |
Shaoqiang Han, Ruiping Zheng, Shuying Li, Bingqian Zhou, Yu Jiang, Keke Fang, Yarui Wei, Baohong Wen, Jianyue Pang, Hengfen Li, Yong Zhang, Yuan Chen, Jingliang Chen. Altered structural covariance network of nucleus accumbens is modulated by illness duration and severity of symptom in depression. Journal of affective disorders. vol 324. 2023-01-07. PMID:36608848. |
patients with depression exhibited altered structural covariance of nacc connected to key brain regions in reward system including the medial orbitofrontal cortex, amygdala, insula, parahippocampa gyrus, precuneus, thalamus, hippocampus and cerebellum. |
2023-01-07 |
2023-08-14 |
human |
Kyrsten Kawazoe, Ryan McGlynn, Wilder Felix, Raquel Sevilla, Siyang Liao, Praveen Kulkarni, Craig F Ferri. Dose-dependent effects of esketamine on brain activity in awake mice: A BOLD phMRI study. Pharmacology research & perspectives. vol 10. issue 6. 2022-12-12. PMID:36504448. |
it was hypothesized the prefrontal cortex, hippocampus, and brain areas associated with reward and motivation would show a dose-dependent increase in brain activity. |
2022-12-12 |
2023-08-14 |
mouse |
Robin Hellerstedt, Deborah Talm. Reward does not modulate forgetting in free recall tests. Learning & memory (Cold Spring Harbor, N.Y.). vol 29. issue 12. 2022-11-29. PMID:36446602. |
reward is thought to attenuate forgetting through the automatic effect of dopamine on hippocampal memory traces. |
2022-11-29 |
2023-08-14 |
human |
Yanjun Sun, Lisa M Giocom. Neural circuit dynamics of drug-context associative learning in the mouse hippocampus. Nature communications. vol 13. issue 1. 2022-11-07. PMID:36344498. |
using longitudinal calcium imaging in freely behaving mice, we find that unlike the associative learning of natural reward, drug-context associations for psychostimulants and opioids are encoded in a specific subset of hippocampal neurons. |
2022-11-07 |
2023-08-14 |
mouse |
Seetha Krishnan, Chad Heer, Chery Cherian, Mark E J Sheffiel. Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal. Nature communications. vol 13. issue 1. 2022-11-05. PMID:36333323. |
hippocampal place cells support reward-related spatial memories by forming a cognitive map that over-represents reward locations. |
2022-11-05 |
2023-08-14 |
mouse |
Seetha Krishnan, Chad Heer, Chery Cherian, Mark E J Sheffiel. Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal. Nature communications. vol 13. issue 1. 2022-11-05. PMID:36333323. |
thus, internal states of high reward expectation enhance encoding of spatial memories by reinforcing hippocampal cognitive maps associated with reward. |
2022-11-05 |
2023-08-14 |
mouse |
William C Griffin, Marcelo F Lopez, John J Woodward, Howard C Becke. Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice. Alcohol (Fayetteville, N.Y.). 2022-11-03. PMID:36328184. |
facilitated by its connectivity with other parts of the brain such as the nucleus accumbens (nac), the ventral hippocampus (vhc) supports many behaviors, including those related to reward seeking and addiction. |
2022-11-03 |
2023-08-14 |
mouse |
Johannes B Mahr, Bob Fische. Internally Triggered Experiences of Hedonic Valence in Nonhuman Animals: Cognitive and Welfare Considerations. Perspectives on psychological science : a journal of the Association for Psychological Science. 2022-10-26. PMID:36288434. |
these hippocampal activations coordinate with neural reward and fear centers as well as sensory and cortical areas in ways that are associated with conscious episodic mental imagery in humans. |
2022-10-26 |
2023-08-14 |
rat |
Ali Veisi, Hossein Khaleghzadeh-Ahangar, Mojdeh Fattahi, Abbas Haghparas. The Role of Orexin-1 Receptors Within the Hippocampal CA1 Area in the Extinction and Reinstatement of Methamphetamine-Seeking Behaviors. Neurochemical research. 2022-10-25. PMID:36284025. |
the orexin system is highly implicated in processing reward and addiction through connections with critical areas such as the hippocampus. |
2022-10-25 |
2023-08-14 |
rat |
Ashley J McFalls, Christopher Jenney, Rachel S Stanford, Emma Woodward, Andras Hajnal, Patricia S Grigson, Kent E Vran. Greater Avoidance of a Saccharin Cue Paired with Passive Delivery of Heroin is Associated with a Select Increase in Expression of CRFR2 and CRFbp in the Hippocampus in Rats. Brain research bulletin. 2022-10-13. PMID:36228871. |
in a rodent model of self-administration and reward devaluation, we previously showed that animals that suppress intake of a drug-paired saccharin cue show greater addiction-like behaviors, as well as increased gene-expression of elements of the corticotropin releasing factor (crf) pathway in the prefrontal cortex (mpfc), hippocampus (hipp), and ventral tegmental area (vta). |
2022-10-13 |
2023-08-14 |
rat |
Edmund T Rolls, Sylvia Wirth, Gustavo Deco, Chu-Chung Huang, Jianfeng Fen. The human posterior cingulate, retrosplenial, and medial parietal cortex effective connectome, and implications for memory and navigation. Human brain mapping. 2022-09-30. PMID:36178249. |
this connectivity implicates it in hippocampal episodic memory, providing routes for "what," reward and semantic schema-related information to access the hippocampus. |
2022-09-30 |
2023-08-14 |
human |