All Relations between hippocampus and bmal1

Publication Sentence Publish Date Extraction Date Species
Kaili Du, Qianwen Shi, Xiuya Zhou, Lifei Zhang, Hongliang Su, Chao Zhang, Zhiwen Wei, Ting Liu, Li Wang, Xiaohui Wang, Bin Cong, Keming Yu. Melatonin attenuates fentanyl - induced behavioral sensitization and circadian rhythm disorders in mice. Physiology & behavior. 2024-03-16. PMID:38492912. the accompanying changes in the expression of brain and muscle arnt-like (bmal1), tyrosine hydroxylase (th), and monoamine oxidase a (mao-a) in relevant brain regions including the suprachiasmatic nucleus (scn), nucleus accumbens (nac), prefrontal cortex (pfc), and hippocampus (hip) were investigated by western blot assays to dissect the mechanism by which melatonin modulates fentanyl - induced behavioral sensitization and circadian rhythm disorders. 2024-03-16 2024-03-19 mouse
Xuebing Zhang, Suihong Huang, Jin Young Ki. Cell-type specific circadian transcription factor BMAL1 roles in excitotoxic hippocampal lesions to enhance neurogenesis. iScience. vol 27. issue 2. 2024-02-02. PMID:38303690. cell-type specific circadian transcription factor bmal1 roles in excitotoxic hippocampal lesions to enhance neurogenesis. 2024-02-02 2024-02-04 Not clear
Xuebing Zhang, Suihong Huang, Jin Young Ki. Cell-type specific circadian transcription factor BMAL1 roles in excitotoxic hippocampal lesions to enhance neurogenesis. iScience. vol 27. issue 2. 2024-02-02. PMID:38303690. in the dentate gyrus of excitotoxic hippocampal lesions, reduced bmal1 in granule cells precedes apoptosis. 2024-02-02 2024-02-04 Not clear
Dan-Dan Xu, Zhi-Qi Hou, Ya-Yun Xu, Jun Liang, Ye-Jun Gao, Chen Zhang, Fan Guo, Dan-Dan Huang, Jin-Fang Ge, Qing-Rong Xi. Potential Role of Bmal1 in Lipopolysaccharide-Induced Depression-Like Behavior and its Associated "Inflammatory Storm". Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 19. issue 1. 2024-02-02. PMID:38305948. furthermore, protein expression levels of the circadian locomotor output cycles kaput, cryptochrome 2, and period 2 was significantly reduced in the hippocampus of lps-challenged rats, whereas bmal1 expression was significantly increased in the hippocampus but decreased in the hypothalamus, where it was co-located with neurons, microglia, and astrocytes. 2024-02-02 2024-02-04 rat
Chunli Zou, Tingting Yang, Jiuhong Zhang, Xiao Chen, Jing Zhao, Desheng Wu, Chen Yang, Peiyi Liu, Xinfeng Huang, Jianjun Liu, Benhong X. A quantitative proteomic study reveals oxidative stress and synapse-related proteins contributed to TDCIPP exposure induced neurotoxicity. Ecotoxicology and environmental safety. vol 271. 2024-01-23. PMID:38262093. proteomic and bioinformatic analyses revealed dysregulation of numerous hippocampal proteins, particularly those associated with synapses (pkn1) or oxidative stress (gstm4, nqo1, and bmal1), which was further confirmed by western blot analysis. 2024-01-23 2024-01-26 rat
Yao Zuo, Yuanyuan Hou, Yunlei Wang, Linran Yuan, Lingna Cheng, Tong Zhan. Circadian misalignment impairs oligodendrocyte myelination via Bmal1 overexpression leading to anxiety and depression-like behaviors. Journal of pineal research. vol 76. issue 1. 2024-01-19. PMID:38241675. mechanistically, we identified upregulation of bmal1 in the pfc and hippocampal regions of cm mice at night, when genes related to mature ol and myelination should be highly expressed. 2024-01-19 2024-01-22 mouse
Ilaria Barone, Nicole M Gilette, Hannah Hawks-Mayer, Jonathan Handy, Kevin J Zhang, Fortunate F Chifamba, Engie Mostafa, Erin M Johnson-Venkatesh, Yan Sun, Jennifer M Gibson, Alexander Rotenberg, Hisashi Umemori, Peter T Tsai, Jonathan O Lipto. Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity. Science advances. vol 9. issue 43. 2023-10-25. PMID:37878694. synaptic bmal1 phosphorylation controls circadian hippocampal plasticity. 2023-10-25 2023-11-08 Not clear
Ilaria Barone, Nicole M Gilette, Hannah Hawks-Mayer, Jonathan Handy, Kevin J Zhang, Fortunate F Chifamba, Engie Mostafa, Erin M Johnson-Venkatesh, Yan Sun, Jennifer M Gibson, Alexander Rotenberg, Hisashi Umemori, Peter T Tsai, Jonathan O Lipto. Synaptic BMAL1 phosphorylation controls circadian hippocampal plasticity. Science advances. vol 9. issue 43. 2023-10-25. PMID:37878694. we report that bmal1 rhythmically localizes to hippocampal synapses in a manner dependent on its phosphorylation at ser 2023-10-25 2023-11-08 Not clear
Jing Yin, Chun-Mei Tuo, Kai-Yue Yu, Xiao-Hong Hu, Yan-Ying Fan, Mei-Na W. Diurnal Characteristics of the Orexin System Genes and Its Effects on Pathology at Early Stage in 3xTg-AD Mice. Neuromolecular medicine. 2023-10-16. PMID:37843792. the results showed that the diurnal mrna expression profiles of ppo, ox1r, ox2r, bace2, bmal1, per1, per2 and cry1 in the hypothalamus, and gene expression of ox1r, ox2r, bace1, bmal1, per1 and cry2 in the hippocampus in 3xtg-ad mice were different from that in wt mice. 2023-10-16 2023-11-08 mouse
Tenna Bering, Camilla Gadgaard, Henrik Vorum, Bent Honoré, Martin Fredensborg Rat. Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. Glia. 2023-07-20. PMID:37470358. diurnal proteome profile of the mouse cerebral cortex: conditional deletion of the bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. 2023-07-20 2023-08-14 mouse
Tenna Bering, Camilla Gadgaard, Henrik Vorum, Bent Honoré, Martin Fredensborg Rat. Diurnal proteome profile of the mouse cerebral cortex: Conditional deletion of the Bmal1 circadian clock gene elevates astrocyte protein levels and cell abundance in the neocortex and hippocampus. Glia. 2023-07-20. PMID:37470358. the proteome of the bmal1 cko cerebral cortex was dominated by upregulated proteins expressed in astrocytes, including gfap (4-fold) and fabp7 (>20-fold), in both the neocortex and hippocampus. 2023-07-20 2023-08-14 mouse
Xinran Gao, Yadong Wei, Huaizhi Sun, Shengwei Hao, Mengdie Ma, Huimin Sun, Dandan Zang, Congcong Qi, Jinfang G. Role of Bmal1 in Type 2 Diabetes Mellitus-Related Glycolipid Metabolic Disorder and Neuropsychiatric Injury: Involved in the Regulation of Synaptic Plasticity and Circadian Rhythms. Molecular neurobiology. 2023-05-01. PMID:37126129. consistently, the protein expression of synaptic plasticity proteins and circadian rhythm-related proteins and the positive fluorescence intensity of mt1b and bmal1 were decreased in the hippocampus of hfd/stz-induced mice or pa-challenged ht-22 cells. 2023-05-01 2023-08-14 mouse
Juan Chen, Lijun Xiao, Ying Chen, Wei Li, Yinan Liu, Ying Zhou, Hong Ta. YT521-B homology domain containing 1 ameliorates mitochondrial damage and ferroptosis in sleep deprivation by activating the sirtuin 1/nuclear factor erythroid-derived 2-like 2/heme oxygenase 1 pathway. Brain research bulletin. 2023-03-19. PMID:36935054. in mice, the cognitive impairment and clock and bmal1 levels in hippocampal tissues were assessed. 2023-03-19 2023-08-14 mouse
Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.). vol 165. 2023-03-04. PMID:36869551. in hypothalamus and hippocampus, clock (bmal1 and clock) and tight junction (ocln and tjp2) genes were improved by prebiotics, and corticotropin-releasing hormone receptor genes, crf1 and crf2, were also significantly regulated for mitigation of depression and anxiety caused by sleep deprivation. 2023-03-04 2023-08-14 mouse
Hao Wu, Yong Liu, Lishuo Liu, Qiang Meng, Changwang Du, Kuo Li, Shan Dong, Yong Zhang, Huanfa Li, Hua Zhan. Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34261484. we first investigated the levels of bmal1 and other clock proteins in the hippocampus of subjects with epilepsy to define the function of bmal1. 2021-08-12 2023-08-13 human
Hao Wu, Yong Liu, Lishuo Liu, Qiang Meng, Changwang Du, Kuo Li, Shan Dong, Yong Zhang, Huanfa Li, Hua Zhan. Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:34261484. knockout of bmal1 in hippocampal dentate gyrus (dg) neurons of bmal1 2021-08-12 2023-08-13 human
Shunpei Moriya, Hitoshi Takahashi, Daiki Masukawa, Makiko Yamada, Jun Ishigooka, Katsuji Nishimur. Ziprasidone, a second-generation antipsychotic, affects core clock gene mRNA expression in mice. Journal of pharmacological sciences. vol 144. issue 1. 2020-10-29. PMID:32624301. zip significantly increased per1, per2, and bmal1 mrna 2 h after the lights were turned off (zt14) in the hippocampus, but not in the amygdala. 2020-10-29 2023-08-13 mouse
Xiao Wu, Xuguang Liu, Zhongkun Jing, Yang Chen, Huahui Liu, Wenbin M. Moxibustion benignantly regulates circadian rhythm of REV-ERBα in RA rats. American journal of translational research. vol 12. issue 5. 2020-09-28. PMID:32509155. rt-pcr was used to measure the relatively expression quantity of rev-erbα, clock, bmal1, and per2 in hypothalamus, hippocampus, and adrenal gland. 2020-09-28 2023-08-13 rat
Shunsuke Hasegawa, Hotaka Fukushima, Hiroshi Hosoda, Tatsurou Serita, Rie Ishikawa, Tomohiro Rokukawa, Ryouka Kawahara-Miki, Yue Zhang, Miho Ohta, Shintaro Okada, Toshiyuki Tanimizu, Sheena A Josselyn, Paul W Frankland, Satoshi Kid. Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation. Nature communications. vol 10. issue 1. 2020-04-02. PMID:31852900. here, we show that hippocampal clock controlled by the circadian-dependent transcription factor bmal1 regulates time-of-day retrieval profile. 2020-04-02 2023-08-13 mouse
Shunsuke Hasegawa, Hotaka Fukushima, Hiroshi Hosoda, Tatsurou Serita, Rie Ishikawa, Tomohiro Rokukawa, Ryouka Kawahara-Miki, Yue Zhang, Miho Ohta, Shintaro Okada, Toshiyuki Tanimizu, Sheena A Josselyn, Paul W Frankland, Satoshi Kid. Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation. Nature communications. vol 10. issue 1. 2020-04-02. PMID:31852900. inducible transgenic dominant negative bmal1 (dnbmal1) expression in mouse forebrain or hippocampus disrupted retrieval of hippocampal memories at zeitgeber time 8-12, independently of retention delay, encoding time and zeitgeber entrainment cue. 2020-04-02 2023-08-13 mouse