| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiabao Hou, Qianni Shen, Xing Wan, Bo Zhao, Yang Wu, Zhongyuan Xi. REM sleep deprivation-induced circadian clock gene abnormalities participate in hippocampal-dependent memory impairment by enhancing inflammation in rats undergoing sevoflurane inhalation. Behavioural brain research. vol 364. 2020-03-09. PMID:30779975. |
western blot analysis revealed that sleep deprivation inhibited hippocampal bmal1 and egr1 expression for more than 7 days after sevoflurane inhalation. |
2020-03-09 |
2023-08-13 |
rat |
| Fang Li, Qing Yun Huang, Si Jia Liu, Zhongxin Guo, Xin Xin Xiong, Lin Gui, Hui Juan Shu, Shao Ming Huang, Guohe Tan, Yuan Yuan Li. [The role of Bmal1 in neuronal radial migration and axonal projection of the embryonic mouse cerebral cortex]. Yi chuan = Hereditas. vol 41. issue 6. 2019-08-14. PMID:31257200. |
it was recently found to regulate the proliferation of hippocampal neuronal progenitor/precursor cells (npcs), implicating bmal1 in the brain development. |
2019-08-14 |
2023-08-13 |
mouse |
| Glenn R Yamakawa, Connor Lengkeek, Sabrina Salberg, Simon C Spanswick, Richelle Mychasiu. Behavioral and pathophysiological outcomes associated with caffeine consumption and repetitive mild traumatic brain injury (RmTBI) in adolescent rats. PloS one. vol 12. issue 11. 2017-11-28. PMID:29108016. |
finally, modifications to expression of 12 genes (adora2a, app, aqp4, bdnf, bmal1, clock, cry, gfap, orx1, orx2, per, tau), in the prefrontal cortex, hippocampus, and/or the hypothalamus were assessed. |
2017-11-28 |
2023-08-13 |
rat |
| Korey Stevanovic, Amara Yunus, Aurelie Joly-Amado, Marcia Gordon, David Morgan, Danielle Gulick, Joshua Gamsb. Disruption of normal circadian clock function in a mouse model of tauopathy. Experimental neurology. vol 294. 2017-08-17. PMID:28461004. |
finally, disruption of the cyclic expression of per2 and bmal1, another core circadian clock protein, is evident in the tg4510 hippocampus. |
2017-08-17 |
2023-08-13 |
mouse |
| Shunpei Moriya, Yu Tahara, Hiroyuki Sasaki, Jun Ishigooka, Shigenobu Shibat. Housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes Per1, Per2, and Bmal1 in the amygdala and hippocampus of mice. Neuroscience research. vol 99. 2016-08-19. PMID:26026603. |
housing under abnormal light-dark cycles attenuates day/night expression rhythms of the clock genes per1, per2, and bmal1 in the amygdala and hippocampus of mice. |
2016-08-19 |
2023-08-13 |
mouse |
| Lauren E Chun, Elizabeth R Woodruff, Sarah Morton, Laura R Hinds, Robert L Spence. Variations in Phase and Amplitude of Rhythmic Clock Gene Expression across Prefrontal Cortex, Hippocampus, Amygdala, and Hypothalamic Paraventricular and Suprachiasmatic Nuclei of Male and Female Rats. Journal of biological rhythms. vol 30. issue 5. 2016-06-15. PMID:26271538. |
this study examined basal clock gene expression (per1, per2, bmal1 mrna) in the scn, prefrontal cortex (pfc), rostral agranular insula, hypothalamic paraventricular nucleus (pvn), amygdala, and hippocampus of male and female rats at 4-h intervals throughout a 12:12 h light:dark cycle. |
2016-06-15 |
2023-08-13 |
rat |
| Lauren E Chun, Elizabeth R Woodruff, Sarah Morton, Laura R Hinds, Robert L Spence. Variations in Phase and Amplitude of Rhythmic Clock Gene Expression across Prefrontal Cortex, Hippocampus, Amygdala, and Hypothalamic Paraventricular and Suprachiasmatic Nuclei of Male and Female Rats. Journal of biological rhythms. vol 30. issue 5. 2016-06-15. PMID:26271538. |
there was a significant rhythm of per1, per2, and bmal1 in the scn, pfc, insula, pvn, subregions of the hippocampus, and amygdala with a 24-h period, suggesting the importance of an oscillating molecular clock in extra-scn brain regions. |
2016-06-15 |
2023-08-13 |
rat |
| b' Evelin Antonieli da Silva Santos, Thalita Ewellyn Batista Sales Marques, Helo\\xc3\\xadsa de Carvalho Matos, Jo\\xc3\\xa3o Pereira Leite, Norberto Garcia-Cairasco, Maria Luisa Pa\\xc3\\xa7\\xc3\\xb3-Larson, Daniel Leite G\\xc3\\xb3es Gita\\xc3\\xa. Diurnal Variation Has Effect on Differential Gene Expression Analysis in the Hippocampus of the Pilocarpine-Induced Model of Mesial Temporal Lobe Epilepsy. PloS one. vol 10. issue 10. 2016-06-10. PMID:26473354.' |
for this, we have selected six core clock genes (per1, per3, bmal1, clock, cry1 and cry2), whose rhythmic expression pattern in hippocampus had been previously reported. |
2016-06-10 |
2023-08-13 |
rat |
| b' Evelin Antonieli da Silva Santos, Thalita Ewellyn Batista Sales Marques, Helo\\xc3\\xadsa de Carvalho Matos, Jo\\xc3\\xa3o Pereira Leite, Norberto Garcia-Cairasco, Maria Luisa Pa\\xc3\\xa7\\xc3\\xb3-Larson, Daniel Leite G\\xc3\\xb3es Gita\\xc3\\xa. Diurnal Variation Has Effect on Differential Gene Expression Analysis in the Hippocampus of the Pilocarpine-Induced Model of Mesial Temporal Lobe Epilepsy. PloS one. vol 10. issue 10. 2016-06-10. PMID:26473354.' |
next, we confirmed the temporal profiling of per1, per3, bmal1, cry1 and cry2 mrna levels in the hippocampus of naive rats by both acrophase and circwave statistical tests for circadian analysis. |
2016-06-10 |
2023-08-13 |
rat |
| Amira A H Ali, Beryl Schwarz-Herzke, Anna Stahr, Timour Prozorovski, Orhan Aktas, Charlotte von Gal. Premature aging of the hippocampal neurogenic niche in adult Bmal1-deficient mice. Aging. vol 7. issue 6. 2016-04-06. PMID:26142744. |
as proliferation of neuronal progenitor/precursor cells (npcs) is enhanced in young bmal1(-/-) mice, we tested the hypothesis that this results in premature aging of hippocampal neurogenic niche in adult bmal1(-/-) mice as compared to wildtype littermates. |
2016-04-06 |
2023-08-13 |
mouse |
| Tomoko Ikeno, Randy J Nelso. Acute melatonin treatment alters dendritic morphology and circadian clock gene expression in the hippocampus of Siberian hamsters. Hippocampus. vol 25. issue 2. 2015-09-16. PMID:25160468. |
however, melatonin treatment increased both period1 and bmal1 expression in the hippocampus, suggesting that melatonin affected molecular oscillations in the hippocampus. |
2015-09-16 |
2023-08-13 |
Not clear |
| Brooke D Rakai, Michael J Chrusch, Simon C Spanswick, Richard H Dyck, Michael C Antl. Survival of adult generated hippocampal neurons is altered in circadian arrhythmic mice. PloS one. vol 9. issue 6. 2015-07-03. PMID:24941219. |
in the present study, neurogenesis in the hippocampal subgranular zone was examined in arrhythmic bmal1 knockout (-ko) mice and their rhythmic heterozygous and wildtype littermates. |
2015-07-03 |
2023-08-13 |
mouse |
| Sarah M Wardlaw, Trongha X Phan, Amit Saraf, Xuanmao Chen, Daniel R Stor. Genetic disruption of the core circadian clock impairs hippocampus-dependent memory. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 8. 2015-05-12. PMID:25034823. |
we conclude that critical signaling events in the hippocampus required for memory depend on bmal1. |
2015-05-12 |
2023-08-13 |
mouse |
| Shunpei Moriya, Yu Tahara, Hiroyuki Sasaki, Yutaro Hamaguchi, Daisuke Kuriki, Ryosuke Ishikawa, Jun Ishigooka, Shigenobu Shibat. Effect of quetiapine on Per1, Per2, and Bmal1 clock gene expression in the mouse amygdala and hippocampus. Journal of pharmacological sciences. vol 125. issue 3. 2015-02-23. PMID:24965164. |
effect of quetiapine on per1, per2, and bmal1 clock gene expression in the mouse amygdala and hippocampus. |
2015-02-23 |
2023-08-13 |
mouse |
| Nelson Vilches, Carlos Spichiger, Natalia Mendez, Lorena Abarzua-Catalan, Hugo A Galdames, David G Hazlerigg, Hans G Richter, Claudia Torres-Farfa. Gestational chronodisruption impairs hippocampal expression of NMDA receptor subunits Grin1b/Grin3a and spatial memory in the adult offspring. PloS one. vol 9. issue 3. 2015-01-15. PMID:24663672. |
the hippocampus of fetuses gestated under light:dark photoperiod (12:12 ld) displayed daily oscillatory expression of the clock genes bmal1 and per2, clock-controlled genes mtnr1b, slc2a4, nr3c1 and nmda receptor subunits 1b-3a-3b. |
2015-01-15 |
2023-08-12 |
rat |
| Tomoko Ikeno, Zachary M Weil, Randy J Nelso. Photoperiod affects the diurnal rhythm of hippocampal neuronal morphology of Siberian hamsters. Chronobiology international. vol 30. issue 9. 2014-05-02. PMID:23879697. |
in the present study, we examined diurnal and seasonal differences in hippocampal neuronal morphology, as well as mrna expression of the neurotrophic factors (i.e., brain-derived neurotrophic factor [bdnf], tropomyosin receptor kinase b [trkb; a receptor for bdnf], and vascular endothelial growth factor [vegf]) and a circadian clock gene, bmal1, in the hippocampus of siberian hamsters. |
2014-05-02 |
2023-08-12 |
Not clear |
| Erik S Musiek, Miranda M Lim, Guangrui Yang, Adam Q Bauer, Laura Qi, Yool Lee, Jee Hoon Roh, Xilma Ortiz-Gonzalez, Joshua T Dearborn, Joseph P Culver, Erik D Herzog, John B Hogenesch, David F Wozniak, Krikor Dikranian, Benoit I Giasson, David R Weaver, David M Holtzman, Garret A Fitzgeral. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. The Journal of clinical investigation. vol 123. issue 12. 2014-02-04. PMID:24270424. |
we observed that deletion of circadian clock transcriptional activators aryl hydrocarbon receptor nuclear translocator-like (bmal1) alone, or circadian locomotor output cycles kaput (clock) in combination with neuronal pas domain protein 2 (npas2), induced severe age-dependent astrogliosis in the cortex and hippocampus. |
2014-02-04 |
2023-08-12 |
mouse |
| Wen-Gao Jiang, Su-Xia Li, Jian-Feng Liu, Yan Sun, Shuang-Jiang Zhou, Wei-Li Zhu, Jie Shi, Lin L. Hippocampal CLOCK protein participates in the persistence of depressive-like behavior induced by chronic unpredictable stress. Psychopharmacology. vol 227. issue 1. 2014-01-28. PMID:23263459. |
the circadian proteins clock and bmal1 are abundantly expressed but function differently in the suprachiasmatic nucleus (scn) and hippocampus. |
2014-01-28 |
2023-08-12 |
Not clear |
| Lorena S Navigatore-Fonzo, Rebeca L Golini, Ivana T Ponce, Silvia M Delgado, Maria G Plateo-Pignatari, María S Gimenez, Ana C Anzulovic. Retinoic acid receptors move in time with the clock in the hippocampus. Effect of a vitamin-A-deficient diet. The Journal of nutritional biochemistry. vol 24. issue 5. 2013-12-10. PMID:22902328. |
previously, we showed that vitamin a deficiency modifies clock bmal1 and per1 as well as bdnf and neurogranin daily rhythmicity in the rat hippocampus when animals are maintained under 12-h-light:12-h-dark conditions. |
2013-12-10 |
2023-08-12 |
rat |
| Lorena S Navigatore-Fonzo, Rebeca L Golini, Ivana T Ponce, Silvia M Delgado, Maria G Plateo-Pignatari, María S Gimenez, Ana C Anzulovic. Retinoic acid receptors move in time with the clock in the hippocampus. Effect of a vitamin-A-deficient diet. The Journal of nutritional biochemistry. vol 24. issue 5. 2013-12-10. PMID:22902328. |
our objectives were (a) to analyze whether rarα, rarβ and rxrβ exhibit a circadian variation in the rat hippocampus and (b) to investigate the effect of a vitamin-a-deficient diet on the circadian expression of bmal1, per1 and retinoic acid receptors (rars and rxrβ) genes. |
2013-12-10 |
2023-08-12 |
rat |