| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
the present study demonstrated for the first time that acute as well as subchronic (4\xe2\x80\xafdays) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3\xe2\x80\xafmg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the \xce\xb2-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-03-06 |
rat |
| Vincenzo Cimini, Susan Van Noorden, Cristina Terlizzi, Giovanna Giuseppina Altobell. Calcium/Calmodulin-Dependent Kinases in the Hypothalamus, Pituitary, and Pineal Gland: An Overview. International journal of endocrinology vol 2022 issue 2023 36601542 |
melatonin activates hippocampal camkii, which then influences dendritogenesis. |
2023-01-05 |
2023-01-30 |
rat |
| Somoday Hazra, Joyeeta Dutta Hazra, Rani Amit Bar-On, Yanhong Duan, Shahaf Edut, Xiaohua Cao, Gal Richter-Levi. The role of hippocampal CaMKII in resilience to trauma-related psychopathology. Neurobiology of stress vol 21 issue 2022 36532378 |
the role of hippocampal camkii in resilience to trauma-related psychopathology. |
2022-12-19 |
2023-01-30 |
rat |
| Somoday Hazra, Joyeeta Dutta Hazra, Rani Amit Bar-On, Yanhong Duan, Shahaf Edut, Xiaohua Cao, Gal Richter-Levi. The role of hippocampal CaMKII in resilience to trauma-related psychopathology. Neurobiology of stress vol 21 issue 2022 36532378 |
in light of the established role of hippocampal synaptic plasticity in stress and the essential role of ca2+/calmodulin-dependent protein kinase ii (camkii) in hippocampal based synaptic plasticity, we pharmacologically inhibited camkii or knocked-down (kd) \xce\xb1camkii (in two separate experiments) in the dorsal dentate gyrus of the hippocampus (ddg) following exposure to the same trauma paradigm. |
2022-12-19 |
2023-01-30 |
rat |
| Zheng-Mao Li, Xiu-Xiu Liu, Chen Li, Zhao-Cong Wei, Yi Shi, Heng-Yi Song, Xiang Chen, Yu Zhang, Jia-Wei Li, Rui-Fang Zhu, Ben-Hui Hu, Wei-Feng Ye, Da Huo, Guo-Jun Jiang, Takuya Sasaki, Li Zhang, Feng Han, Ying-Mei L. Decreased synapse-associated proteins are associated with the onset of epileptic memory impairment in endothelial MedComm vol 3 issue 3 2022 35770064 |
moreover, the persistent epileptic seizures induce aberrant changes in phosphorylation of camkii protein in the hippocampus of spontaneous epileptic mice. |
2022-06-30 |
2023-01-27 |
mouse |
| Zhilu Zou, Jiaru Huang, Qingqing Yang, Yuxuan Zhang, Bo Xu, Ping Wang, Gang Che. Repeated Yueju, But Not Fluoxetine, Induced Sustained Antidepressant Activity in a Mouse Model of Chronic Learned Helplessness: Involvement of CaMKII Signaling in the Hippocampus. Evidence-based complementary and alternative medicine : eCAM vol 2022 issue 2022 35251201 |
repeated yueju, but not fluoxetine, induced sustained antidepressant activity in a mouse model of chronic learned helplessness: involvement of camkii signaling in the hippocampus. |
2022-03-07 |
2023-01-27 |
Not clear |
| Ting Wang, Bo Ruan, Jinxin Wang, Zhiyong Zhou, Xulan Zhang, Changcheng Zhang, Haixia Zhao, Yuanjian Yang, Ding Yua. Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticity. Neurochemistry international vol 152 issue 2021 34743016 |
importantly, our data demonstrated strongly enhanced expression of nlrp3, asc and caspase-1 in the hippocampus of aged rats as well as decreased ampa receptor and phosphorylated levels of camkii and creb in the hippocampus of natural aging rats. |
2021-12-11 |
2023-01-26 |
rat |
| Ting Wang, Bo Ruan, Jinxin Wang, Zhiyong Zhou, Xulan Zhang, Changcheng Zhang, Haixia Zhao, Yuanjian Yang, Ding Yua. Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticity. Neurochemistry international vol 152 issue 2021 34743016 |
furthermore, nlrp3 inflammasome inhibitor elevated the surface expression of ampa receptor and the phosphorylated levels of camkii, creb in hippocampus, and finally contributed to the attenuation of hippocampal long-term potentiation (ltp) deficits and the improvement of cognitive decline of natural aging rats. |
2021-12-11 |
2023-01-26 |
rat |
| Inci Turan, Hale Sayan Ozacmak, V Haktan Ozacmak, Meryem Ergenc, Taner Bayraktaro\\xc4\\x9fl. The effects of glucagon-like peptide 1 receptor agonist (exenatide) on memory impairment, and anxiety- and depression-like behavior induced by REM sleep deprivation. Brain research bulletin vol 174 issue 2021 34146656 |
the levels of ca2+/calmodulin-dependent protein kinase ii (camkii) and postsynaptic density proteins 95 (psd95) were measured in tissues of hippocampus and prefrontal cortex. |
2021-12-10 |
2023-01-26 |
rat |
| Inci Turan, Hale Sayan Ozacmak, V Haktan Ozacmak, Meryem Ergenc, Taner Bayraktaro\\xc4\\x9fl. The effects of glucagon-like peptide 1 receptor agonist (exenatide) on memory impairment, and anxiety- and depression-like behavior induced by REM sleep deprivation. Brain research bulletin vol 174 issue 2021 34146656 |
contents of camkii and psd95 decreased in hippocampus of sd rats. |
2021-12-10 |
2023-01-26 |
rat |
| Inci Turan, Hale Sayan Ozacmak, V Haktan Ozacmak, Meryem Ergenc, Taner Bayraktaro\\xc4\\x9fl. The effects of glucagon-like peptide 1 receptor agonist (exenatide) on memory impairment, and anxiety- and depression-like behavior induced by REM sleep deprivation. Brain research bulletin vol 174 issue 2021 34146656 |
exenatide treatment improved the impaired memory of sd rats and increased camkii content in hippocampus there was no difference in mda and gsh levels among groups. |
2021-12-10 |
2023-01-26 |
rat |
| Inci Turan, Hale Sayan Ozacmak, V Haktan Ozacmak, Meryem Ergenc, Taner Bayraktaro\\xc4\\x9fl. The effects of glucagon-like peptide 1 receptor agonist (exenatide) on memory impairment, and anxiety- and depression-like behavior induced by REM sleep deprivation. Brain research bulletin vol 174 issue 2021 34146656 |
in conclusion, treatment with exenatide, at least in part, prevented from these cognitive and behavioral changes possibly through normalizing camkii levels in the hippocampus. |
2021-12-10 |
2023-01-26 |
rat |
| Andressa Radiske, Maria Carolina Gonzalez, Janine I Rossato, G\\xc3\\xaanedy Apolin\\xc3\\xa1rio, Jo\\xc3\\xa3o R de Oliveira, Lia R M Bevilaqua, Mart\\xc3\\xadn Cammarot. Avoidance memory requires CaMKII activity to persist after recall. Molecular brain vol 14 issue 1 2021 34775982 |
using pharmacological, electrophysiological and optogenetic tools, we found that in adult male wistar rats hippocampal camkii is necessary to reconsolidate avoidance memory, but not to keep it stored while inactive, and that blocking reconsolidation via camkii inhibition erases learned avoidance responses. |
2021-12-10 |
2023-01-26 |
rat |
| Chang-Hai Fu, Xue-Yan Han, Lei Tong, Peng-Yin Nie, Yue-Dong Hu, Li-Li J. miR-142 downregulation alleviates the impairment of spatial learning and memory, reduces the level of apoptosis, and upregulates the expression of pCaMKII and BAI3 in the hippocampus of APP/PS1 transgenic mice. Behavioural brain research vol 414 issue 2021 34302879 |
in addition, the reduction of phosphorylation of synapsin i and calcium/calmodulin-dependent protein kinase ii (camkii), as well as the expression of psd-95 in the hippocampus of app/ps1 transgenic mice, were significantly restored by inhibiting mir-142. |
2021-11-04 |
2023-01-26 |
mouse |
| Roman Sloutsky, Noelle Dziedzic, Matthew J Dunn, Rachel M Bates, Ana P Torres-Ocampo, Sivakumar Boopathy, Brendan Page, John G Weeks, Luke H Chao, Margaret M Stratto. Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation. Science signaling vol 13 issue 641 2021 32694170 |
heterogeneity in human hippocampal camkii transcripts reveals allosteric hub-dependent regulation. |
2021-11-01 |
2023-01-26 |
human |
| ManKin Choy, Ehsan Dadgar-Kiani, Greg O Cron, Ben A Duffy, Florian Schmid, Bradley J Edelman, Mazen Asaad, Russell W Chan, Shahabeddin Vahdat, Jin Hyung Le. Repeated hippocampal seizures lead to brain-wide reorganization of circuits and seizure propagation pathways. Neuron vol issue 2021 34706219 |
here, we developed an optogenetic kindling model through repeated stimulation of ventral hippocampal camkii neurons in adult rats. |
2021-10-27 |
2023-01-26 |
rat |
| Jannike M Andersen, Siri H Opdal, Christian P M\\xc3\\xbcller, Fernando Boi. CaMKII is activated in opioid induced conditioned place preference, but \\xce\\xb1CaMKII Thr286 autophosphorylation is not necessary for its establishment. Behavioural brain research vol 390 issue 2021 32407818 |
to study the contribution of camkii in opioid induced conditioned learning, we examined how establishment of conditioned place preference (cpp) induced by 10 or 30 \xce\xbcmol/kg morphine or its active metabolite morphine-6-glucuronide (m6g) affects the levels and thr286 autophosphorylation of the \xce\xb1- and \xce\xb2-isoforms of camkii, as well as \xce\xb2-actin levels, in dorsal and ventral striatum and in hippocampus of mice. |
2021-10-25 |
2023-01-26 |
mouse |
| Jannike M Andersen, Siri H Opdal, Christian P M\\xc3\\xbcller, Fernando Boi. CaMKII is activated in opioid induced conditioned place preference, but \\xce\\xb1CaMKII Thr286 autophosphorylation is not necessary for its establishment. Behavioural brain research vol 390 issue 2021 32407818 |
whereas an acute single administration of morphine or m6g caused increases in camkii levels and phosphorylation at thr286 and \xce\xb2-actin in striatal areas, cpp induced by these opioids was accompanied primarily by an increase in the protein levels of both camkii isoforms and \xce\xb2-actin in dorsal striatum and hippocampus. |
2021-10-25 |
2023-01-26 |
mouse |
| Jinxin Wang, Dongfan Wang, Zhiyong Zhou, Xulan Zhang, Changcheng Zhang, Yumin He, Chaoqi Liu, Chengfu Yuan, Ding Yuan, Ting Wan. Saponins from Panax japonicus alleviate HFD-induced impaired behaviors through inhibiting NLRP3 inflammasome to upregulate AMPA receptors. Neurochemistry international vol 148 issue 2021 34129896 |
our results showed that hfd-fed mice caused behavioral disorders, neuronal degeneration as well as elevated neuroinflammation, which was partly involved in nlrp3 inflammasome that finally resulted in decreased protein levels of ampa receptors and down-regulated phosphorylated levels of camkii and creb in cortex and hippocampus. |
2021-09-08 |
2023-01-26 |
mouse |
| Ting-Ting Chen, Xue Zhou, Yi-Ni Xu, Yue Li, Xiao-Ying Wu, Quan Xiang, Ling-Yun Fu, Xiao-Xia Hu, Ling Tao, Xiang-Chun She. Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca Aging vol 13 issue 7 2021 33714957 |
immunohistochemical and western blot analyses revealed that gas attenuated hippocampal levels of lc3 (microtubule-associated protein 1 light chain 3), p62, and phosphorylated camkii (ca |
2021-08-16 |
2023-01-26 |
rat |