| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rabia Anjum, Vernon R J Clarke, Yutaro Nagasawa, Hideji Murakoshi, Suzanne Paradi. Rem2 interacts with CaMKII at synapses and restricts long-term potentiation in hippocampus. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38558974. |
rem2 interacts with camkii at synapses and restricts long-term potentiation in hippocampus. |
2024-04-01 |
2024-04-04 |
Not clear |
| Yutaro Nagasawa, Hiromi H Ueda, Haruka Kawabata, Hideji Murakosh. LOV2-based photoactivatable CaMKII and its application to single synapses: Local Optogenetics. Biophysics and physicobiology. vol 20. issue 2. 2024-03-18. PMID:38496236. |
to address this, we developed an optogenetic tool named photoactivatable camkii (pacamkii) by fusing a light-sensitive domain (lov2) to camkiiα, which is a protein abundantly expressed in neurons of the cerebrum and hippocampus and essential for synaptic plasticity. |
2024-03-18 |
2024-03-20 |
Not clear |
| Yutaro Nagasawa, Hiromi H Ueda, Haruka Kawabata, Hideji Murakosh. LOV2-based photoactivatable CaMKII and its application to single synapses: Local Optogenetics. Biophysics and physicobiology. vol 20. issue 2. 2024-03-18. PMID:38496236. |
combining photoactivatable camkii with two-photon excitation, we successfully activated it in single spines, inducing synaptic plasticity (long-term potentiation) in hippocampal neurons. |
2024-03-18 |
2024-03-20 |
Not clear |
| Jiawei Yang, Ying Wang, Yuyan Xia, Yajie Ren, Zhi Wang, Xin Meng, Shuangyue Li, Xiaohui Liu, Jing Sha. PFOS Elicits Cytotoxicity in Neuron Through Astrocyte-Derived CaMKII-DLG1 Signaling In Vitro Rat Hippocampal Model. Neurochemical research. 2024-02-23. PMID:38393622. |
in the present study, the role of astrocyte-derived calmodulin-dependent protein kinase ii (camkii)-phosphorylated discs large homolog 1 (dlg1) signaling in pfos eliciting cytotoxicity in neuron was explored with primary cultured hippocampal astrocyte and neuron. |
2024-02-23 |
2024-02-25 |
rat |
| Lalit P Chandravanshi, Prashant Agrawal, Hany W Darwish, Surendra Kumar Trigu. Impairments of Spatial Memory and N-methyl-d-aspartate Receptors and Their Postsynaptic Signaling Molecules in the Hippocampus of Developing Rats Induced by As, Pb, and Mn Mixture Exposure. Brain sciences. vol 13. issue 12. 2023-12-23. PMID:38137163. |
the nmda receptor and several important signaling proteins are involved in learning, memory, and synaptic plasticity in the hippocampus, including camkii, postsynaptic density protein-95 (psd-95), synaptic ras gtpase activating protein (syngap), a negative regulator of ras-mapk activity, and creb. |
2023-12-23 |
2023-12-25 |
rat |
| Lalit P Chandravanshi, Prashant Agrawal, Hany W Darwish, Surendra Kumar Trigu. Impairments of Spatial Memory and N-methyl-d-aspartate Receptors and Their Postsynaptic Signaling Molecules in the Hippocampus of Developing Rats Induced by As, Pb, and Mn Mixture Exposure. Brain sciences. vol 13. issue 12. 2023-12-23. PMID:38137163. |
declined protein expressions of nr2a, psd-95, p- camkii, and pcreb were observed in the metal mix-exposed rats, while the expression of syngap was found to be enhanced in the hippocampus as compared to the controls on pd60. |
2023-12-23 |
2023-12-25 |
rat |
| Andressa Radiske, Carla Miranda de Castro, Janine I Rossato, Maria Carolina Gonzalez, Martín Cammarot. Hippocampal CaMKII inhibition induces reactivation-dependent amnesia for extinction memory and causes fear relapse. Scientific reports. vol 13. issue 1. 2023-12-08. PMID:38066022. |
hippocampal camkii inhibition induces reactivation-dependent amnesia for extinction memory and causes fear relapse. |
2023-12-08 |
2023-12-17 |
rat |
| Andressa Radiske, Carla Miranda de Castro, Janine I Rossato, Maria Carolina Gonzalez, Martín Cammarot. Hippocampal CaMKII inhibition induces reactivation-dependent amnesia for extinction memory and causes fear relapse. Scientific reports. vol 13. issue 1. 2023-12-08. PMID:38066022. |
our results indicate that hippocampal camkii is necessary for fear extinction reconsolidation, and suggest that modulation of its activity around the time of recall controls the inhibition that extinction exerts on learned fear. |
2023-12-08 |
2023-12-17 |
rat |
| Jun Yang, Rui-Ning Ma, Jia-Min Dong, Shu-Qun Hu, Yong Liu, Jing-Zhi Ya. Phosphorylation of 4.1N by CaMKII regulates the trafficking of GluA1-containing AMPA receptors during long-term potentiation in acute rat hippocampal brain slices. Neuroscience. 2023-11-22. PMID:37993087. |
phosphorylation of 4.1n by camkii regulates the trafficking of glua1-containing ampa receptors during long-term potentiation in acute rat hippocampal brain slices. |
2023-11-22 |
2023-11-29 |
rat |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
merazin hydrate produces rapid antidepressant effect by activating camkii to promote neuronal activities and proliferation in hippocampus. |
2023-11-04 |
2023-11-08 |
mouse |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
furthermore, we also found that the phosphorylated expression of calcium/calmodulin-dependent protein kinase ii (camkii) was significantly reduced by cums in hippocampus, which was also reversed by mh. |
2023-11-04 |
2023-11-08 |
mouse |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
in addition, pharmacological inhibition of camkii by using kn-93 (a camkii antagonist) blocked the mh's up-regulation of cfos and ki67 in hippocampal dg. |
2023-11-04 |
2023-11-08 |
mouse |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
to sum up, this study demonstrated that mh produced rapid antidepressant effects by activating camkii to promote neuronal activities and proliferation in hippocampus. |
2023-11-04 |
2023-11-08 |
mouse |
| Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Ji-Eun Ki. PDI augments kainic acid-induced seizure activity and neuronal death by inhibiting PP2A-GluA2-PICK1-mediated AMPA receptor internalization in the mouse hippocampus. Scientific reports. vol 13. issue 1. 2023-08-25. PMID:37626185. |
in the present study, we found that under physiological condition pdi knockdown increased camkii activity (phosphorylation) in the mouse hippocampus. |
2023-08-25 |
2023-09-07 |
mouse |
| Atefeh Bakhtazad, Afsaneh Asgari Taei, Fatemeh Parvizi, Mehdi Kadivar, Maryam Farahmandfa. Repeated Pre-exposure to Morphine Inhibited the Amnesic Effect of Ethanol on Spatial Memory: Involvement of CaMKII and BDNF. Alcohol (Fayetteville, N.Y.). 2023-08-19. PMID:37597575. |
also, we assessed how these drug-exposures influence the expression level of camkii and bdnf in the hippocampus and amygdala. |
2023-08-19 |
2023-09-07 |
rat |
| Atefeh Bakhtazad, Afsaneh Asgari Taei, Fatemeh Parvizi, Mehdi Kadivar, Maryam Farahmandfa. Repeated Pre-exposure to Morphine Inhibited the Amnesic Effect of Ethanol on Spatial Memory: Involvement of CaMKII and BDNF. Alcohol (Fayetteville, N.Y.). 2023-08-19. PMID:37597575. |
our findings suggest that sub-chronic morphine treatment reverses ethanol-induced spatial memory impairment which could be explained by modulating camkii and bdnf mrna expressions in the hippocampus and amygdala. |
2023-08-19 |
2023-09-07 |
rat |
| Yuri Elias Rodrigues, Cezar M Tigaret, Hélène Marie, Cian O'Donnell, Romain Velt. A stochastic model of hippocampal synaptic plasticity with geometrical readout of enzyme dynamics. eLife. vol 12. 2023-08-17. PMID:37589251. |
we apply this readout to a multi-timescale model of hippocampal synaptic plasticity induction that includes electrical dynamics, calcium, camkii and calcineurin, and accurate representation of intrinsic noise sources. |
2023-08-17 |
2023-09-07 |
Not clear |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
the present study demonstrated for the first time that acute as well as subchronic (4 days) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3 mg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the β-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-08-14 |
rat |
| Vincenzo Cimini, Susan Van Noorden, Cristina Terlizzi, Giovanna Giuseppina Altobell. Calcium/Calmodulin-Dependent Kinases in the Hypothalamus, Pituitary, and Pineal Gland: An Overview. International journal of endocrinology. vol 2022. 2023-01-05. PMID:36601542. |
melatonin activates hippocampal camkii, which then influences dendritogenesis. |
2023-01-05 |
2023-08-14 |
human |
| Somoday Hazra, Joyeeta Dutta Hazra, Rani Amit Bar-On, Yanhong Duan, Shahaf Edut, Xiaohua Cao, Gal Richter-Levi. The role of hippocampal CaMKII in resilience to trauma-related psychopathology. Neurobiology of stress. vol 21. 2022-12-19. PMID:36532378. |
the role of hippocampal camkii in resilience to trauma-related psychopathology. |
2022-12-19 |
2023-08-14 |
rat |