| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Orly Lazarov, Muskan Gupta, Pavan Kumar, Zachery Morrissey, Trongha Pha. Memory Circuits in Dementia: The Engram, Hippocampal Neurogenesis and Alzheimer's disease. Progress in neurobiology. 2024-04-03. PMID:38570083. |
we primarily focus on the dentate gyrus (dg) of the hippocampus, which is a key area of episodic memory formation. |
2024-04-03 |
2024-04-06 |
Not clear |
| Orly Lazarov, Muskan Gupta, Pavan Kumar, Zachery Morrissey, Trongha Pha. Memory Circuits in Dementia: The Engram, Hippocampal Neurogenesis and Alzheimer's disease. Progress in neurobiology. 2024-04-03. PMID:38570083. |
critically, studies of the engram in the dg using these technologies have shown the important contribution of hippocampal neurogenesis for memory in both health and ad. |
2024-04-03 |
2024-04-06 |
Not clear |
| Lijing Wang, Lauren Park, Weisheng Wu, Dana King, Alexis Vega-Medina, Frank Raven, Jessy Martinez, Amy Ensing, Katherine McDonald, Zhongying Yang, Sha Jiang, Sara J Ato. Sleep-dependent engram reactivation during hippocampal memory consolidation associated with subregion-specific biosynthetic changes. iScience. vol 27. issue 4. 2024-03-25. PMID:38523798. |
we labeled context-encoding engram neurons in the hippocampal dentate gyrus (dg) and assessed reactivation of these neurons after fear learning. |
2024-03-25 |
2024-03-27 |
Not clear |
| Lijing Wang, Lauren Park, Weisheng Wu, Dana King, Alexis Vega-Medina, Frank Raven, Jessy Martinez, Amy Ensing, Katherine McDonald, Zhongying Yang, Sha Jiang, Sara J Ato. Sleep-dependent engram reactivation during hippocampal memory consolidation associated with subregion-specific biosynthetic changes. iScience. vol 27. issue 4. 2024-03-25. PMID:38523798. |
together, these data suggest that the dg is critical for sleep-dependent memory consolidation, and that the effects of sleep loss on the hippocampus are highly subregion-specific. |
2024-03-25 |
2024-03-27 |
Not clear |
| Yue Zhang, Xian-Qiang Zhang, Wei-Pan Niu, Meng Sun, Yanan Zhang, Ji-Tao Li, Tian-Mei Si, Yun-Ai S. TAAR1 in dentate gyrus is involved in chronic stress-induced impairments in hippocampal plasticity and cognitive function. Progress in neuro-psychopharmacology & biological psychiatry. 2024-03-21. PMID:38514038. |
however, it remains unknown whether taar1 in dentate gyrus (dg) mediate chronic stress-induced negative effects on hippocampal plasticity and related behavior in mice. |
2024-03-21 |
2024-03-24 |
mouse |
| Krista A Mitchnick, Hannah Marlatte, Zorry Belchev, Fuqiang Gao, R Shayna Rosenbau. Differential contributions of the hippocampal dentate gyrus and cornu ammonis 1 subfield to mnemonic discrimination. Hippocampus. 2024-03-19. PMID:38501294. |
here, we demonstrated dissociations in these memory processes in two unique individuals with near-selective bilateral damage within the hippocampus, affecting the dentate gyrus (dg) in case bl and the cornu ammonis 1 (ca1) subfield in case br. |
2024-03-19 |
2024-03-21 |
Not clear |
| Hadi Moatamed Jahromi, Ali Rafati, Saied Karbalay-Doust, Somaye Keshavarz, Maryam Nase. The combination treatment of hypothermia and intranasal insulin ameliorates the structural and functional changes in a rat model of traumatic brain injury. Brain structure & function. 2024-03-18. PMID:38498064. |
tbi led to an increase in the total volume of hippocampal subfields ca1 and dg and a decrease in the total number of neurons and non-neuronal cells in both sub-regions, which was associated with anxiety-like behavior and memory impairment. |
2024-03-18 |
2024-03-20 |
rat |
| Hadi Moatamed Jahromi, Ali Rafati, Saied Karbalay-Doust, Somaye Keshavarz, Maryam Nase. The combination treatment of hypothermia and intranasal insulin ameliorates the structural and functional changes in a rat model of traumatic brain injury. Brain structure & function. 2024-03-18. PMID:38498064. |
our study suggests that the combined treatment of ht and ins could prevent increased hippocampal volume and cell loss in ca1 and dg sub-regions and consequently improve anxiety-like behaviors and memory impairment following tbi. |
2024-03-18 |
2024-03-20 |
rat |
| Yue Li, Yanmin Luo, Peilin Zhu, Xin Liang, Jing Li, Xiaoyun Dou, Li Liu, Lu Qin, Mei Zhou, Yuhui Deng, Lin Jiang, Shun Wang, Wenyu Yang, Jing Tang, Yong Tan. Running exercise improves astrocyte loss, morphological complexity and astrocyte-contacted synapses in the hippocampus of CUS-induced depression model mice. Pharmacology, biochemistry, and behavior. 2024-03-17. PMID:38494007. |
the expression of astrocyte- and synapse-related proteins in the hippocampus; astrocyte process lengths, process numbers, and dendritic arborization; and the number of astrocyte-contacted psd95 positive synapses in the ca2-3 and dg regions were significantly decreased in the mice with depressive-like behavior, and running exercise successfully reserved these changes. |
2024-03-17 |
2024-03-20 |
mouse |
| Yuhui Deng, Xin Liang, Yue Li, Lin Jiang, Jin Wang, Jing Tang, Jing Li, Yuhan Xie, Kai Xiao, Peilin Zhu, Yijing Guo, Yanmin Luo, Yong Tan. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice. Neuropharmacology. 2024-03-16. PMID:38492883. |
moreover, the downregulation of hippocampal pgc-1α expression resulted in a decrease in the number of excitatory synapses in the dg and in the protein expression of ucp2 in the hippocampus. |
2024-03-16 |
2024-03-19 |
mouse |
| Yuhui Deng, Xin Liang, Yue Li, Lin Jiang, Jin Wang, Jing Tang, Jing Li, Yuhan Xie, Kai Xiao, Peilin Zhu, Yijing Guo, Yanmin Luo, Yong Tan. PGC-1α in the hippocampus mediates depressive-like and stress-coping behaviours and regulates excitatory synapses in the dentate gyrus in mice. Neuropharmacology. 2024-03-16. PMID:38492883. |
this suggests that hippocampal pgc-1α is involved in regulating depressive-like and stress-coping behaviours and modulating the number of excitatory synapses in the dg. |
2024-03-16 |
2024-03-19 |
mouse |
| Saiying Wang, Haijun Zhang, Rui Liu, Peijun Han, Qi Yang, Caiyan Cheng, Yue Chen, Zheng Rong, Chang Su, Fei Li, Gaofei Wei, Minggao Zhao, Le Yan. Influenza A Virus PB1-F2 Induces Affective Disorder by Interfering Synaptic Plasticity in Hippocampal Dentate Gyrus. Molecular neurobiology. 2024-03-15. PMID:38488981. |
in this study, we constructed and injected pb1-f2 into the hippocampal dentate gyrus (dg), a region closely associated with newborn neurons and neural development, to evaluate its influence on negative affective behaviors and learning performance in mice. |
2024-03-15 |
2024-03-18 |
mouse |
| Qian Tang, Ryota Ojiro, Shunsuke Ozawa, Xinyu Zou, Junta Nakahara, Tomohiro Nakao, Mihoko Koyanagi, Meilan Jin, Toshinori Yoshida, Makoto Shibutan. DNA methylation-altered genes in the rat hippocampal neurogenic niche after continuous exposure to amorphous curcumin. Journal of chemical neuroanatomy. 2024-03-15. PMID:38490283. |
rat offspring who are exposed to an amorphous formula of curcumin (cur) from the embryonic stage have anti-anxiety-like behaviors, enhanced fear extinction learning, and increased synaptic plasticity in the hippocampal dentate gyrus (dg). |
2024-03-15 |
2024-03-18 |
rat |
| Poornima D E Weerasinghe-Mudiyanselage, Sohi Kang, Joong-Sun Kim, Sung-Ho Kim, Hongbing Wang, Taekyun Shin, Changjong Moo. Changes in structural plasticity of hippocampal neurons in an animal model of multiple sclerosis. Zoological research. vol 45. issue 2. 2024-03-14. PMID:38485508. |
dendritic complexity was largely affected in the cornu ammonis 1 (ca1) and ca3 apical and dentate gyrus (dg) subregions of the hippocampus during the chronic phase, while this effect was only noted in the ca1 apical subregion in the early phase. |
2024-03-14 |
2024-03-17 |
mouse |
| Joana Martins-Macedo, Bruna Araújo, Sandra I Anjo, Tiago Silveira-Rosa, Patrícia Patrício, Nuno Dinis Alves, Joana M Silva, Fábio G Teixeira, Bruno Manadas, Ana J Rodrigues, Angelo C Lepore, António J Salgado, Eduardo D Gomes, Luísa Pint. Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation. Molecular psychiatry. 2024-03-07. PMID:38454085. |
to examine the role of newly formed glia, we transplanted glial restricted precursors (grps) into the adult hippocampal dentate gyrus (dg), or injected their secreted factors (secretome), into a previously validated transgenic gfap-tk rat line, in which cytogenesis is transiently compromised. |
2024-03-07 |
2024-03-10 |
rat |
| Pierre Mortessagne, Estelle Cartier, Maddalena Balia, Murielle Fèvre, Fiona Corailler, Cyril Herry, Djoher Nora Abrous, Arne Battefeld, Emilie Pacar. Genetic labeling of embryonically-born dentate granule neurons in young mice using the Penk Scientific reports. vol 14. issue 1. 2024-02-29. PMID:38424161. |
genetic labeling of embryonically-born dentate granule neurons in young mice using the penk the dentate gyrus (dg) of the hippocampus is a mosaic of dentate granule neurons (dgns) accumulated throughout life. |
2024-02-29 |
2024-03-03 |
mouse |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
since glutamatergic transmission and nmda receptor neural pathways in hippocampal dentate gyrus (dg) are essential in the learning and memory, we aimed to investigate glutamate (glu) and nmda receptor signaling of dg in spatial learning and memory in diet-induced obesity (dio) rats. |
2024-02-28 |
2024-03-01 |
rat |
| Dingding Lv, Bin Xiao, Huaying Liu, Linping Wang, Yingshun Li, Yin Hua Zhang, Qinghua Ji. Enhanced NMDA receptor pathway and glutamate transmission in the hippocampal dentate gyrus mediate the spatial learning and memory impairment of obese rats. Pflugers Archiv : European journal of physiology. 2024-02-28. PMID:38416255. |
in conclusion, the enhancement of glu-nmda receptor transmission in the hippocampal dg contributes to the impairment of spatial learning and memory in dio rats, maybe via the modulation of camkii-creb-bdnf signaling pathway. |
2024-02-28 |
2024-03-01 |
rat |
| Allegra Kawles, Rachel Keszycki, Grace Minogue, Antonia Zouridakis, Ivan Ayala, Nathan Gill, Alyssa Macomber, Vivienne Lubbat, Christina Coventry, Emily Rogalski, Sandra Weintraub, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias. Acta neuropathologica communications. vol 12. issue 1. 2024-02-23. PMID:38389095. |
paraffin-embedded sections were stained immunohistochemically with at8 to visualize pick bodies, and unbiased stereological analysis was performed in up to six regions bilaterally [middle frontal gyrus (mfg), superior temporal gyrus (stg), inferior parietal lobule (ipl), anterior temporal lobe (atl), dentate gyrus (dg) and ca1 of the hippocampus], and unilateral occipital cortex (occ). |
2024-02-23 |
2024-02-25 |
Not clear |
| Erik H Middlebrooks, Vivek Gupta, Amit K Agarwal, Brin E Freund, Steven A Messina, William O Tatum, David S Sabsevitz, Anteneh M Feyissa, Seyed M Mirsattari, Fernando N Galan, Alfredo Quinones-Hinojosa, Sanjeet S Grewal, John V Murra. Radiologic Classification of Hippocampal Sclerosis in Epilepsy. AJNR. American journal of neuroradiology. 2024-02-21. PMID:38383054. |
this framework will not only benefit current clinical evaluations, but also enhance future studies involving high-resolution mri in temporal lobe epilepsy.abbreviations: ca = cornu ammonis; dg = dentate gyrus; hs = hippocampal sclerosis; ilae = international league against epilepsy; srlm = strata radiatum, lacunosum, and moleculare layers; tle = temporal lobe epilepsy. |
2024-02-21 |
2024-02-24 |
Not clear |