| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaitlyn E Dorst, Ryan A Senne, Anh H Diep, Antje R de Boer, Rebecca L Suthard, Heloise Leblanc, Evan A Ruesch, Angela Y Pyo, Sara Skelton, Lucas C Carstensen, Samantha Malmberg, Olivia P McKissick, John H Bladon, Steve Ramire. Hippocampal engrams generate variable behavioral responses and brain-wide network states. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-12-05. PMID:38050098. |
to address this, we optogenetically reactivated a fear engram in the dentate gyrus (dg) subregion of the hippocampus across three distinct contexts in male mice. |
2023-12-05 |
2023-12-10 |
mouse |
| Yanyi Ding, Long Li, Sinuo Wang, Yajun Cao, Minguang Yang, Yaling Dai, Huawei Lin, Jianhong Li, Yulu Liu, Zhifu Wang, Weilin Liu, Jing Ta. Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model. Biological research. vol 56. issue 1. 2023-12-02. PMID:38041203. |
impaired pattern separation occurs in the early stage of alzheimer's disease (ad), and hippocampal dentate gyrus (dg) neurogenesis participates in pattern separation. |
2023-12-02 |
2023-12-10 |
mouse |
| Anbiao Wu, Jiyan Zhan. Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. Journal of neuroinflammation. vol 20. issue 1. 2023-11-28. PMID:38012702. |
neuroinflammation has been reported to be involved in mdd through distinct neurobiological mechanisms, among which the dysregulation of neurogenesis in the dentate gyrus (dg) of the hippocampus (hpc) is receiving increasing attention. |
2023-11-28 |
2023-11-29 |
Not clear |
| Anbiao Wu, Jiyan Zhan. Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. Journal of neuroinflammation. vol 20. issue 1. 2023-11-28. PMID:38012702. |
the dg of the hippocampus is one of two niches for neurogenesis in the adult mammalian brain, and neurotrophic factors are fundamental regulators of this neurogenesis process. |
2023-11-28 |
2023-11-29 |
Not clear |
| Yan Cao, Pan Liu, Hongfei Bian, Sixuan Jin, Jiaqi Liu, Ning Yu, Huan Cui, Fengrun Sun, Xiaojing Qian, Wenying Qiu, Chao M. Reduced neurogenesis in human hippocampus with Alzheimer's disease. Brain pathology (Zurich, Switzerland). 2023-11-27. PMID:38012054. |
in this study, we observed a significant presence of neurogenic cells in the hippocampus's dentate gyrus (dg) region in 30 individuals, including 14 individuals diagnosed with ad-related neuropathological changes and the remaining 16 individuals without any neurological diseases. |
2023-11-27 |
2023-11-29 |
human |
| Matin Baghani, Arad Bolouri-Roudsari, Reyhaneh Askari, Abbas Haghparas. Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress-induced analgesia in the animal model of chronic pain. Behavioural brain research. vol 459. 2023-11-25. PMID:37995966. |
since orexin neuropeptides are involved in pain modulation, and orexin neurons, primarily located in the lateral hypothalamus (lh), project to various hippocampal regions, such as the dentate gyrus (dg), the current study aimed to examine the role of orexin receptors within the dg region in the restraint sia in the animal model of chronic pain. |
2023-11-25 |
2023-11-28 |
rat |
| Dore Loef, Indira Tendolkar, Philip F P van Eijndhoven, Jeroen J M Hoozemans, Mardien L Oudega, Annemieke J M Rozemuller, Paul J Lucassen, Annemiek Dols, Anke A Dijkstr. Electroconvulsive therapy is associated with increased immunoreactivity of neuroplasticity markers in the hippocampus of depressed patients. Translational psychiatry. vol 13. issue 1. 2023-11-20. PMID:37981649. |
in rodents, electroconvulsive shocks increase proliferation and the expression of plasticity markers in the hippocampal dentate gyrus (dg), suggesting increased neurogenesis. |
2023-11-20 |
2023-11-29 |
human |
| Aiai Dong, Zhen Gao, Haijun Wang, Ronglin Wu, Weifeng Wang, Xiaofei Jin, Yufang Ji, Faming Yang, Tao Zhu, Ziwen Jiang, Yongrong Xu, Jilong Guo, Laixi J. Acupuncture Alleviates Chronic Ischemic White Matter Injury in SHR Rats via JNK-NMDAR Circuit. Molecular neurobiology. 2023-11-17. PMID:37976026. |
myelin density was detected by luxol fast blue (lfb) staining, also axon arrangement, myelin integrity, and thickness of neurons were detected by electron microscopy; neuronal morphology and the number of nissl bodies in the hippocampus were detected by nissl staining, dendritic spine density changes were detected by golgi staining, and jnk, nmdar1, and n-methyl-d-receptor 2b (nmdar2b) in dg, ca3 region of hippocampus were detected by immunohistochemistry, protein expression of p-jnk/jnk, p-nmdar1/nmdar1, nmdar2b, gsk3β protein expression in the fimbria of hippocampus was detected by western blot. |
2023-11-17 |
2023-11-20 |
rat |
| Abigail C Toltin, Abdelmadjid Belkadi, Laura M Gamba, Muhammad M Hossai. The Preventive Effects of Salubrinal against Pyrethroid-Induced Disruption of Adult Hippocampal Neurogenesis in Mice. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958604. |
salubrinal prevented hippocampal er stress, as indicated by decreased levels of c/ebp-homologous protein (chop) and transcription factor 4 (atf4) and attenuated deltamethrin-induced reductions in brdu-, ki-67-, and dcx-positive cells in the dentate gyrus (dg) of the hippocampus. |
2023-11-14 |
2023-11-20 |
mouse |
| Selena Singh, Suzanna Becker, Thomas Trappenberg, Abraham Nune. Granule cells perform frequency-dependent pattern separation in a computational model of the dentate gyrus. Hippocampus. 2023-11-11. PMID:37950569. |
we aim to study, in a computational model of the hippocampal dentate gyrus (dg), the network and cellular mechanisms governing this putative "u"-shaped ps relationship. |
2023-11-11 |
2023-11-20 |
Not clear |
| Yasunori Takahashi, Ryota Ojiro, Risako Yamashita, Saori Shimizu, Natsuno Maeda, Xinyu Zou, Qian Tang, Shunsuke Ozawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Suppression of neurogranin expression by disruption of epigenetic DNA methylation in hippocampal mature granule cells after developmental exposure to neurotoxicants in rats. Toxicology letters. 2023-11-05. PMID:37926403. |
we previously performed comprehensive analyses of genes hypermethylated promoter regions and downregulated transcripts in the hippocampal dentate gyrus (dg) of rats upon weaning at postnatal day (pnd) 21 after developmental exposure to 6-propyl-2-thiouracil (ptu), valproic acid, and glycidol (gly), all of which are known to show irreversible effects on hippocampal neurogenesis in adulthood on pnd 77. |
2023-11-05 |
2023-11-08 |
rat |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
moreover, mh could not only significantly up-regulated the expressions of cfos, but also obviously increased the number of ki67 positive cells in hippocampal dentate gyrus (dg). |
2023-11-04 |
2023-11-08 |
mouse |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
in addition, pharmacological inhibition of camkii by using kn-93 (a camkii antagonist) blocked the mh's up-regulation of cfos and ki67 in hippocampal dg. |
2023-11-04 |
2023-11-08 |
mouse |
| Keqiang Gao, Mengxi Hu, Jiyang Li, Ziyi Li, Wei Xu, Zhiyu Qian, Fan Gao, Tengfei M. Drug-detecting bioelectronic nose based on odor cue memory combined with a brain computer interface. Biosensors & bioelectronics. vol 244. 2023-11-03. PMID:37922809. |
first, the rats were trained to generate positive memories of drug odors through food reward training, and multichannel microelectrodes were implanted into the dg region of the hippocampus for responsible memory retrieval, the spike signals of individual neurons and the local field potential signals of population neurons in the brain region were collected for pattern recognition and analysis. |
2023-11-03 |
2023-11-08 |
rat |
| Roya Homayouni, Kelsey L Canada, Samaah Saifullah, Da' Jonae Foster, Charlotte Thill, Naftali Raz, Ana M Daugherty, Noa Ofe. Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis. Hippocampus. 2023-10-26. PMID:37881160. |
it is comprised of cytoarchitectonically distinct subfields: dentate gyrus (dg), cornu ammonis sectors (ca) 1-4, and subiculum, each of which may be differentially susceptible to neurodevelopmental and neurodegenerative mechanisms. |
2023-10-26 |
2023-11-08 |
human |
| Shaoyi Fang, Zhibin Wu, Yali Guo, Wenjun Zhu, Chunmiao Wan, Naijun Yuan, Jianbei Chen, Wenzhi Hao, Xiaowei Mo, Xiaofang Guo, Lili Fan, Xiaojuan Li, Jiaxu Che. Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics. Frontiers in immunology. vol 14. 2023-10-26. PMID:37881439. |
adult hippocampal neurogenesis generates functional neurons from neural progenitor cells in the hippocampal dentate gyrus (dg) to complement and repair neurons and neural circuits, thus benefiting the treatment of depression. |
2023-10-26 |
2023-11-08 |
Not clear |
| Roya Homayouni, Ana M Daugherty, Qijing Yu, Naftali Raz, Noa Ofe. KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development. Brain structure & function. 2023-10-18. PMID:37853296. |
the hippocampus (hc) consists of cytoarchitectonically and functionally distinct subfields: dentate gyrus (dg), cornu ammonis (ca1-3), and subiculum. |
2023-10-18 |
2023-11-08 |
Not clear |
| Jean Philippe Djientcheu Tientcheu, Florence Tsofack Ngueguim, Racéline Kamkumo Gounoue, Michel Arnaud Mbock, Rodrigue Ngapout, Antoine Kavaye Kandeda, Théophile Dim. The extract of Sclerocarya birrea, Nauclea latifolia, and Piper longum mixture ameliorates diabetes-associated cognitive dysfunction. Metabolic brain disease. 2023-10-11. PMID:37821784. |
fructose/stz administration resulted in t2d, impaired short- and long-term memory, significantly increased oxidative/nitrative stress, pro-inflammatory cytokine levels, acetylcholinesterase activity (ache), hippocampal neuronal loss and degeneration in ca1 and ca3 subfields, and neuronal vacuolation in dg. |
2023-10-11 |
2023-10-15 |
rat |
| Yuk-Hoi Yiu, Christian Leibol. A theory of hippocampal theta correlations accounting for extrinsic and intrinsic sequences. eLife. vol 12. 2023-10-04. PMID:37792453. |
here, we propose a computational model of cornu ammonis 3 (ca3) and dentate gyrus (dg), where sensorimotor input drives the direction-dependent (extrinsic) theta sequences within ca3 reflecting the two-dimensional spatial topology, whereas the intrahippocampal ca3-dg projections concurrently produce intrinsic sequences that are independent of the specific running trajectory. |
2023-10-04 |
2023-10-07 |
Not clear |
| Carmela Belardo, Serena Boccella, Michela Perrone, Antimo Fusco, Andrea Maria Morace, Federica Ricciardi, Roozbe Bonsale, Ines ELBini-Dhouib, Francesca Guida, Livio Luongo, Giacinto Bagetta, Damiana Scuteri, Sabatino Maion. Scopolamine-Induced Memory Impairment in Mice: Effects of PEA-OXA on Memory Retrieval and Hippocampal LTP. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762702. |
consistently, electrophysiological analysis showed ltp recovery in the dg of the hippocampus, while the ach level and choa-t were normalized. |
2023-09-28 |
2023-10-07 |
mouse |