| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alysha A Sultan, Mikaela K Dimick, Clement C Zai, James L Kennedy, Bradley J MacIntosh, Benjamin I Goldstei. The association of CNR1 genetic variants with resting-state functional connectivity in youth bipolar disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 71. 2023-03-27. PMID:36972648. |
regions-of-interests in seed-to-voxel analyses included: bilateral amygdala, hippocampus, nucleus accumbens (nac), and orbitofrontal cortex (ofc). |
2023-03-27 |
2023-08-14 |
human |
| Alysha A Sultan, Mikaela K Dimick, Clement C Zai, James L Kennedy, Bradley J MacIntosh, Benjamin I Goldstei. The association of CNR1 genetic variants with resting-state functional connectivity in youth bipolar disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 71. 2023-03-27. PMID:36972648. |
g-allele was associated with negative connectivity in bd and positive connectivity in hc for: left amygdala seed with right intracalcarine cortex; right nac seed with left inferior frontal gyrus; and right hippocampal seed with bilateral cuneal cortex (all p<0.001). |
2023-03-27 |
2023-08-14 |
human |
| Alysha A Sultan, Mikaela K Dimick, Clement C Zai, James L Kennedy, Bradley J MacIntosh, Benjamin I Goldstei. The association of CNR1 genetic variants with resting-state functional connectivity in youth bipolar disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 71. 2023-03-27. PMID:36972648. |
g-allele was associated with positive connectivity in bd and negative connectivity in hc for: right hippocampal seed with left central opercular cortex (p = 0.001), and left nac seed with left middle temporal cortex (p = 0.002). |
2023-03-27 |
2023-08-14 |
human |
| Yajie Jiang, Manshu Zou, Yeqing Wang, Yuhong Wan. Nucleus Accumbens in the Pathogenesis of Major Depressive Disorder: A Brief Review. Brain research bulletin. 2023-03-08. PMID:36889362. |
extensive studies have demonstrated the involvement of nuclei such as the prefrontal cortex (pfc), hippocampus (hip), nucleus accumbens (nac), hypothalamus, etc., in mdd. |
2023-03-08 |
2023-08-14 |
Not clear |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
the present study demonstrated for the first time that acute as well as subchronic (4 days) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3 mg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the β-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-08-14 |
rat |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
furthermore, following the methamphetamine intravenous self-administration in rats, the 3 mg/kg jmv2959 pretreatment significantly reduced or prevented the methamphetamine-induced significant decrease of hippocampal β-actin and c-fos as well as it prevented the significant decrease of creb in the nac and mpfc. |
2023-03-04 |
2023-08-14 |
rat |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. |
these results imply, that the ghs-r1a antagonist/jmv2959 might reduce/prevent some of the memory-linked molecular changes elicited by methamphetamine addiction within brain structures associated with memory (hipp), reward (nac), and motivation (mpfc), which may contribute to the previously observed significant jmv2959-induced reduction of the methamphetamine self-administration and drug-seeking behavior in the same animals. |
2023-03-04 |
2023-08-14 |
rat |
| Ji-Eun Kim, Hana Park, Tae-Cheon Kan. Peroxiredoxin 6 Regulates Glutathione Peroxidase 1-Medited Glutamine Synthase Preservation in the Hippocampus of Chronic Epilepsy Rats. Antioxidants (Basel, Switzerland). vol 12. issue 1. 2023-01-21. PMID:36671018. |
to elucidate this, the present study was designed to investigate whether nac affects astroglial glutamine synthase (gs) expression mediated by gsh peroxidase 1 (gpx1) and/or peroxiredoxin 6 (prdx6) in the epileptic hippocampus. |
2023-01-21 |
2023-08-14 |
rat |
| Xiao-Bo Wu, Qian Zhu, Ming-Hui Gao, Sheng-Xiang Yan, Pan-Yang Gu, Peng-Fei Zhang, Meng-Lin Xu, Yong-Jing Ga. Excitatory projections from the prefrontal cortex to nucleus accumbens core D1-MSNs and kappa opioid receptor modulate itch-related scratching behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-01-18. PMID:36653189. |
excitatory afferents from the medial prefrontal cortex (mpfc), amygdala, and hippocampus are crucial in tuning the activity of dopamine receptor d1- and d2-expressing medium spiny neurons (drd1- and drd2-msns) in the nac. |
2023-01-18 |
2023-08-14 |
mouse |
| Ekram Mohammadi, Farnaz Nikbakht, Somayeh Vazifekhah, Javad Fahanik Babae, Mohamad Taghi Jogatae. Evaluation the cognition-improvement effects of N-acetyl cysteine in experimental temporal lobe epilepsy in rat. Behavioural brain research. 2022-12-23. PMID:36563904. |
histological analysis showed that nac significantly increased the number of intact neurons in ca3 and hilar areas of the hippocampus following the induction of epilepsy. |
2022-12-23 |
2023-08-14 |
rat |
| Shane A Perrine, Walid F Alsharif, Arman Harutyunyan, Swatabdi Kamal, Nerissa T Viola, Juri G Gelovan. Low- and high-cocaine intake affects the spatial and temporal dynamics of class IIa HDAC expression-activity in the nucleus accumbens and hippocampus of male rats as measured by [18F]TFAHA PET/CT neuroimaging. Addiction neuroscience. vol 4. 2022-12-21. PMID:36540409. |
repeated cocaine alters neuronal function in the nucleus accumbens (nac), a brain region involved in cocaine taking, and in hippocampus (hc), known for contextual and associative learning. |
2022-12-21 |
2023-08-14 |
rat |
| Kıymet Kübra Tüfekci, Elfide Gizem Bakirhan, Funda Terz. A Maternal High-Fat Diet Causes Anxiety-Related Behaviors by Altering Neuropeptide Y1 Receptor and Hippocampal Volumes in Rat Offspring: the Potential Effect of N-Acetylcysteine. Molecular neurobiology. 2022-12-11. PMID:36502431. |
the study results show that nac attenuated anxiety-like behaviors and npy1r expression and also protected hippocampal volume against maternal obesity. |
2022-12-11 |
2023-08-14 |
rat |
| Kıymet Kübra Tüfekci, Elfide Gizem Bakirhan, Funda Terz. A Maternal High-Fat Diet Causes Anxiety-Related Behaviors by Altering Neuropeptide Y1 Receptor and Hippocampal Volumes in Rat Offspring: the Potential Effect of N-Acetylcysteine. Molecular neurobiology. 2022-12-11. PMID:36502431. |
additionally, although there is no direct evidence, maintenance of npy1r expression by nac may be critical for regulating maternal obesity-induced anxiety-related behaviors and hippocampal structure. |
2022-12-11 |
2023-08-14 |
rat |
| Lucia Carboni, Laura Rullo, Francesca Felicia Caputi, Serena Stamatakos, Sanzio Candeletti, Patrizia Romuald. Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430520. |
mrna expression of growth factor and circadian rhythm genes was evaluated by qpcr in the prefrontal cortex (pfcx), hippocampus, nucleus accumbens (nac), amygdala, and hypothalamus. |
2022-11-26 |
2023-08-14 |
rat |
| Lucia Carboni, Laura Rullo, Francesca Felicia Caputi, Serena Stamatakos, Sanzio Candeletti, Patrizia Romuald. Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy. International journal of molecular sciences. vol 23. issue 22. 2022-11-26. PMID:36430520. |
bdnf levels were significantly increased in pfcx and hippocampus by trazodone and in the nac and hypothalamus by citalopram. |
2022-11-26 |
2023-08-14 |
rat |
| Jameel N Hamdan, Jorge A Sierra-Fonseca, Rodolfo J Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E O'Dell, Kristin L Gosselin. Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner. Frontiers in behavioral neuroscience. vol 16. 2022-11-07. PMID:36338879. |
the hippocampus (hipp), medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate putamen (cpu) were isolated from one subgroup of animals and subjected to western blot and protein quantitation for tyrosine hydroxylase (th), α-synuclein (alpha), nmda receptor (nmdar), dopamine receptor-1 (d1) and -2 (d2), dopamine transporter (dat), and postsynaptic density 95 (psd95). |
2022-11-07 |
2023-08-14 |
rat |
| Blake L Elliott, Kimberlee D'Ardenne, Vishnu P Murty, Gene A Brewer, Samuel M McClur. Midbrain-Hippocampus Structural Connectivity Selectively Predicts Motivated Memory Encoding. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-11-04. PMID:36332978. |
functional mri studies show that interactions between the dopaminergic midbrain (sn/vta), hippocampus, and nucleus accumbens (nac) are critical for motivated memory encoding. |
2022-11-04 |
2023-08-14 |
human |
| William C Griffin, Marcelo F Lopez, John J Woodward, Howard C Becke. Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice. Alcohol (Fayetteville, N.Y.). 2022-11-03. PMID:36328184. |
facilitated by its connectivity with other parts of the brain such as the nucleus accumbens (nac), the ventral hippocampus (vhc) supports many behaviors, including those related to reward seeking and addiction. |
2022-11-03 |
2023-08-14 |
mouse |
| Ashley J McFalls, Christopher Jenney, Rachel S Stanford, Emma Woodward, Andras Hajnal, Patricia S Grigson, Kent E Vran. Greater Avoidance of a Saccharin Cue Paired with Passive Delivery of Heroin is Associated with a Select Increase in Expression of CRFR2 and CRFbp in the Hippocampus in Rats. Brain research bulletin. 2022-10-13. PMID:36228871. |
we then assessed gene expression for components of the crf pathway in the mpfc, hipp, vta, amygdala, and nucleus accumbens (nac). |
2022-10-13 |
2023-08-14 |
rat |
| Ezio Carboni, Anna R Cart. BDNF Alterations in Brain Areas and the Neurocircuitry Involved in the Antidepressant Effects of Ketamine in Animal Models, Suggest the Existence of a Primary Circuit of Depression. Journal of integrative neuroscience. vol 21. issue 5. 2022-09-22. PMID:36137960. |
in this review we have examined the role of several brain areas: namely, the hippocampus, the medial prefrontal cortex (mpfc), the nucleus accumbens (nac), the lateral habenula (lhb), the amygdala and the bed nucleus of stria terminalis (bnst). |
2022-09-22 |
2023-08-14 |
Not clear |