| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shu-Ling Chiu, Chih-Ming Chen, Richard L Hugani. ICA69 regulates activity-dependent synaptic strengthening and learning and memory. Frontiers in molecular neuroscience. vol 16. 2023-05-30. PMID:37251649. |
here, we showed that ica69 regulates pick1's distribution in neurons and stability in the mouse hippocampus, which in turn can impact ampar function in the brain. |
2023-05-30 |
2023-08-14 |
mouse |
| Namrata Ramsakha, Prachi Ojha, Subhajit Pal, Sanjeev Routh, Ami Citri, Samarjit Bhattacharyy. A vital role for PICK1 in the differential regulation of metabotropic glutamate receptor internalization and synaptic AMPA receptor endocytosis. The Journal of biological chemistry. 2023-05-20. PMID:37209824. |
applying a "molecular replacement" approach in hippocampal neurons derived from mice, we demonstrate a critical role for protein interacting with c kinase 1 (pick1) in regulating the agonist-induced internalization of mglur1. |
2023-05-20 |
2023-08-14 |
mouse |
| Pola Tuduri, Nathalie Bouquier, Benoit Girard, Enora Moutin, Maxime Thouaye, Julie Perroy, Federica Bertaso, Jeanne Ste. Modulation of hippocampal network oscillation by PICK1-dependent cell surface expression of mGlu3 receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-06. PMID:36202617. |
here we show that mglu3 interacts with pick1 and that this scaffolding protein is important for mglu3 surface expression and function in hippocampal primary cultures. |
2022-10-06 |
2023-08-14 |
Not clear |
| Xuan Ling Hilary Yong, Michael A Cousin, Victor Anggon. PICK1 Controls Activity-Dependent Synaptic Vesicle Cargo Retrieval. Cell reports. vol 33. issue 4. 2021-11-19. PMID:33113376. |
here, we show that pick1 loss of function selectively slows the kinetics of sv endocytosis in primary hippocampal neurons during high-frequency stimulation. |
2021-11-19 |
2023-08-13 |
Not clear |
| Yunchang Mo, Lu Wang, Miao Ren, Wenjing Xie, Xiaoxiao Ye, Bingbing Zhou, Anqi Zhang, Qinxue Dai, Junlu Wan. Electroacupuncture prevents LPS- induced neuroinflammation via upregulation of PICK-TLR4 complexes in the microglia of hippocampus. Brain research bulletin. vol 177. 2021-11-18. PMID:34673136. |
behavioral tests; microglial activity of hippocampus; neuron survival and the inflammatory factors pick1 and tlr4, as well as tlr4-related proteins, such as erk, jnk, and p38, were assessed after ea treatment. |
2021-11-18 |
2023-08-13 |
mouse |
| Olayemi Joseph Olajide, Zainab Omolara Alliy, Daniel Oluwapelumi Ojo, Olajumoke Olamipe Osinubi, Sofiyat Opeyemi Bello, Faaizah Eniola Ibrahim, Faith Ojochenemi Adukwu, Tolulope Olabisi Abikoye, Ismail Temitayo Gbadamosi, Nafisat Yetunde Mutholib, Olawande Bamisi, Olaolu Joseph Ajiboye, Akeem Ayodeji Okesina, Abdulmusawwir Alli-Oluwafuyi, Aboyeji Lukuman Oyewole, Abdulrazaq Bidemi Nafiu, Olugbenga Akinol. Neurobehavioral, neurochemical and synaptic plasticity perturbations during postnatal life of rats exposed to chloroquine in-utero. Neurotoxicology and teratology. vol 86. 2021-08-25. PMID:33845156. |
synaptic marker pick1 expression was also downregulated in the hippocampus but was unperturbed in the pfc and cerebellum. |
2021-08-25 |
2023-08-13 |
rat |
| Jan-Øyvind Lorgen, Daniel Lawer Egbenya, Janniche Hammer, Svend Davange. PICK1 facilitates lasting reduction in GluA2 concentration in the hippocampus during chronic epilepsy. Epilepsy research. vol 137. 2018-06-11. PMID:28888867. |
pick1 facilitates lasting reduction in glua2 concentration in the hippocampus during chronic epilepsy. |
2018-06-11 |
2023-08-13 |
rat |
| Jun Nomura, Geetha Kannan, Toru Takum. Rodent models of genetic and chromosomal variations in psychiatric disorders. Psychiatry and clinical neurosciences. vol 71. issue 8. 2018-02-19. PMID:28317218. |
in addition, we discuss recent unique translational research using rodent models, such as cntnap2 knockout mouse, mecp2 mutant mouse, pick1 knockout mouse, and neonatal ventral hippocampal lesion rat. |
2018-02-19 |
2023-08-13 |
mouse |
| Surya P Pandey, Rakesh Rai, Pankaj Gaur, S Prasa. Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain. Biogerontology. vol 16. issue 3. 2016-02-03. PMID:25559403. |
our data on alterations in the expression of glur2 in the hippocampus during development and aging indicates a high- and low positive correlations with psd95 and stargazin, respectively whereas negative correlation with pick1 except in old age where expression of stargazin is higher and that of pick1 is lower. |
2016-02-03 |
2023-08-13 |
mouse |
| Ya-Nan Wang, Liang Zhou, Yun-Hong Li, Zhen Wang, Ying-Cong Li, Ya-Wen Zhang, Yin Wang, Gang Liu, Ying She. Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904794. |
neurons in the cortex and hippocampus from pick1(-/-) mice showed increased vulnerability to oxidants and reduced capacity to metabolize reactive oxygen species (ros); this was caused by reduced glutathione content and impaired cysteine transport. |
2015-07-16 |
2023-08-13 |
mouse |
| Junyu Xu, Chuen Kam, Jian-Hong Luo, Jun Xi. PICK1 mediates synaptic recruitment of AMPA receptors at neurexin-induced postsynaptic sites. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 46. 2015-02-09. PMID:25392508. |
here, we report that during synaptogenesis induced by neurexin in cultured neurons from rat hippocampus, pick1 recruited ampa receptors to immature postsynaptic sites. |
2015-02-09 |
2023-08-13 |
rat |
| Wei Lu, Latika Khatri, Edward B Zif. Trafficking of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA) receptor subunit GluA2 from the endoplasmic reticulum is stimulated by a complex containing Ca2+/calmodulin-activated kinase II (CaMKII) and PICK1 protein and by release of Ca2+ from internal stores. The Journal of biological chemistry. vol 289. issue 27. 2014-10-14. PMID:24831007. |
here we show that glua2 trafficking from the endoplasmic reticulum (er) to the plasma membrane of cultured hippocampal neurons requires ca(2+) release from internal stores, the activity of ca(2+)/calmodulin activated kinase ii (camkii), and glua2 interaction with the pdz protein, pick1. |
2014-10-14 |
2023-08-13 |
Not clear |
| Daniel L Rocca, Mascia Amici, Anna Antoniou, Elena Blanco Suarez, Nagaraj Halemani, Kai Murk, Jennifer McGarvey, Nadia Jaafari, Jack R Mellor, Graham L Collingridge, Jonathan G Hanle. The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity. Neuron. vol 79. issue 2. 2013-10-17. PMID:23889934. |
expression of mutant arf1 that does not bind pick1 leads to reduced surface levels of glua2-containing ampars and smaller spines in hippocampal neurons, which occludes subsequent nmda-induced ampar internalization and spine shrinkage. |
2013-10-17 |
2023-08-12 |
Not clear |
| Silvia Bassani, Lorenzo A Cingolani, Pamela Valnegri, Alessandra Folci, Jonathan Zapata, Antonella Gianfelice, Carlo Sala, Yukiko Goda, Maria Passafar. The X-linked intellectual disability protein TSPAN7 regulates excitatory synapse development and AMPAR trafficking. Neuron. vol 73. issue 6. 2012-05-15. PMID:22445342. |
these findings indicate that, in hippocampal neurons, tspan7 regulates ampa receptor trafficking by limiting pick1 accessibility to ampa receptors and suggest an additional mechanism for the functional maturation of glutamatergic synapses, whose impairment is implicated in intellectual disability. |
2012-05-15 |
2023-08-12 |
rat |
| Dan-Fang Yu, Peng-Fei Wu, Hui Fu, Jin Cheng, Yuan-Jian Yang, Tao Chen, Li-Hong Long, Jian-Guo Chen, Fang Wan. Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus. Neuroscience letters. vol 497. issue 1. 2011-10-31. PMID:21527319. |
aging-related alterations in the expression and distribution of glur2 and pick1 in the rat hippocampus. |
2011-10-31 |
2023-08-12 |
rat |
| Dan-Fang Yu, Peng-Fei Wu, Hui Fu, Jin Cheng, Yuan-Jian Yang, Tao Chen, Li-Hong Long, Jian-Guo Chen, Fang Wan. Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus. Neuroscience letters. vol 497. issue 1. 2011-10-31. PMID:21527319. |
here, we firstly show that the expression of pick1 and can b decreased significantly in the hippocampus of old rats compared to that of young and adult rats. |
2011-10-31 |
2023-08-12 |
rat |
| Dan-Fang Yu, Peng-Fei Wu, Hui Fu, Jin Cheng, Yuan-Jian Yang, Tao Chen, Li-Hong Long, Jian-Guo Chen, Fang Wan. Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus. Neuroscience letters. vol 497. issue 1. 2011-10-31. PMID:21527319. |
next, we found that in young and adult rats, the distribution of pick1 and glur2 diffused in the cytoplasm of hippocampal neurons, but closely around perinuclear in the hippocampal neurons of old rats. |
2011-10-31 |
2023-08-12 |
rat |
| Dan-Fang Yu, Peng-Fei Wu, Hui Fu, Jin Cheng, Yuan-Jian Yang, Tao Chen, Li-Hong Long, Jian-Guo Chen, Fang Wan. Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus. Neuroscience letters. vol 497. issue 1. 2011-10-31. PMID:21527319. |
these results suggest that the expression of glur2, pick1, pkcα and can b significant decreased in the hippocampus and these alterations may lead to altered distribution of glur2 and pick1 during aging. |
2011-10-31 |
2023-08-12 |
rat |
| Lenora Volk, Chong-Hyun Kim, Kogo Takamiya, Yilin Yu, Richard L Hugani. Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 50. 2011-05-12. PMID:21106762. |
developmental regulation of protein interacting with c kinase 1 (pick1) function in hippocampal synaptic plasticity and learning. |
2011-05-12 |
2023-08-12 |
mouse |
| Lenora Volk, Chong-Hyun Kim, Kogo Takamiya, Yilin Yu, Richard L Hugani. Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 50. 2011-05-12. PMID:21106762. |
however, studies examining the requirement for pick1 in maintaining basal synaptic transmission and regulating synaptic plasticity at hippocampal schaffer collateral-cornu ammonis 1 (sc-ca1) synapses have produced conflicting results. |
2011-05-12 |
2023-08-12 |
mouse |