| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thays Brenner Santos, Cesar Augusto de Oliveira Coelho, Juliana Carlota Kramer-Soares, Paul W Frankland, Maria Gabriela Menezes Oliveir. Reactivation of encoding ensembles in the prelimbic cortex supports temporal associations. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-07. PMID:38454052. |
we used robust activity marking (ram) to selectively manipulate pl neurons activated by cfc-5s learning and targeted recombination in active populations (trap2) mice to label neurons activated by cfc-5s learning and reactivated by memory retrieval in the amygdala, medial prefrontal cortex, hippocampus, perirhinal cortices (per) and subiculum. |
2024-03-07 |
2024-03-10 |
mouse |
| Francesca Girelli, Maria Gloria Rossetti, Cinzia Perlini, Marcella Bellan. Neural correlates of cognitive behavioral therapy-based interventions for bipolar disorder: A scoping review. Journal of psychiatric research. vol 172. 2024-03-06. PMID:38447356. |
in two additional studies, a peculiar pattern of baseline activations in the prefrontal cortex, hippocampus, amygdala, and insula predicted post-treatment improvements in depressive symptoms, emotion dysregulation, and psychosocial functioning, although cbt-specific effects were not shown. |
2024-03-06 |
2024-03-09 |
Not clear |
| Zhaosong Chu, Lijin Yuan, Kun Lian, Mengxin He, Yi Lu, Yuqi Cheng, Xiufeng Xu, Zonglin She. Reduced gray matter volume of the hippocampal tail in melancholic depression: evidence from an MRI study. BMC psychiatry. vol 24. issue 1. 2024-03-05. PMID:38443878. |
this study aims to investigate the volumetric alterations of each subregion of the hippocampus and amygdala in patients with md and non-melancholic depression (nmd). |
2024-03-05 |
2024-03-08 |
Not clear |
| Shanshan Tang, Wen Hu, Helin Zou, Qingyang Luo, Wenwen Deng, Song Ca. The complement system: a potential target for the comorbidity of chronic pain and depression. The Korean journal of pain. 2024-03-04. PMID:38433474. |
the primary potential mechanisms encompass the involvement of the complement cascade c1q/c3-cr3 in the activation of microglia and synaptic pruning in the amygdala and hippocampus, the role of complement cascade c3/c3a-c3ar in the interaction between astrocytes and microglia, leading to synaptic pruning, and the c3a-c3ar axis and c5a-c5ar axis to trigger inflammation within the central nervous system. |
2024-03-04 |
2024-03-06 |
Not clear |
| Miguel Farinha-Ferreira, Daniela M Magalhães, Mariana Neuparth-Sottomayor, Hugo Rafael, Catarina Miranda-Lourenço, Ana M Sebastiã. Unmoving and uninflamed: Characterizing neuroinflammatory dysfunction in the Wistar-Kyoto rat model of depression. Journal of neurochemistry. 2024-03-02. PMID:38430009. |
in a separate cohort, we assessed prefrontal cortex (pfc), hippocampus and amygdala levels of markers of astrocytic (gfap, s100a10) and microglial (iba1, cd86, ym1) activation status, as well as of three key proinflammatory cytokines (il-1β, il-6, tnf-α). |
2024-03-02 |
2024-03-04 |
rat |
| Alexandra C Ritger, Rachel K Parker, Sydney Trask, Nicole C Ferrar. Elevated fear states facilitate ventral hippocampal engagement of basolateral amygdala neuronal activity. Frontiers in behavioral neuroscience. vol 18. 2024-02-29. PMID:38420349. |
the basolateral amygdala (bla) and ventral hippocampus (vh) in particular are two regions that support contextual fear memory processes and share reciprocal connections. |
2024-02-29 |
2024-03-02 |
Not clear |
| Bao-Zhu Yang, Bo Xiang, Tingting Wang, Shuangge Ma, Chiang-Shan R L. Neurogenetic underpinnings of nicotine use severity: Integrating the brain transcriptomes and GWAS variants via network approaches. Psychiatry research. vol 334. 2024-02-29. PMID:38422867. |
eight brain-region-specific coexpression subnetworks were identified in association with cpd: amygdala, hippocampus, medial prefrontal cortex (mpfc), orbitofrontal cortex (opfc), dorsolateral prefrontal cortex, striatum, mediodorsal nucleus of the thalamus (mdthal), and primary motor cortex (m1c). |
2024-02-29 |
2024-03-03 |
human |
| Bao-Zhu Yang, Bo Xiang, Tingting Wang, Shuangge Ma, Chiang-Shan R L. Neurogenetic underpinnings of nicotine use severity: Integrating the brain transcriptomes and GWAS variants via network approaches. Psychiatry research. vol 334. 2024-02-29. PMID:38422867. |
we also identified three hub proteins encoded by grin2a in the amygdala, pmca2 in the hippocampus, mpfc, opfc, striatum, and mdthal, and sv2b in m1c. |
2024-02-29 |
2024-03-03 |
human |
| Xue-Ping Yang, Dan-Dai, Ruo-Xia Chen, Yu-Xuan Li, Xue Rui Lv, Yun L. The expression of ProBDNF and its high affinity receptor P75NTR in the neurons of emotion-related brain regions of post-stroke depression rats. Brain research. 2024-02-29. PMID:38423239. |
to investigate the expression of the precursor of brain-derived neurotrophic factor (probdnf) and its high-affinity receptor p75ntr in neurons of emotion-related brain areas (prefrontal cortex, hippocampus, and amygdala) in rats with post-stroke depression (psd), and to explore the expression levels of probdnf and p75ntr in neurons of emotion-related brain areas by injecting tissue plasminogen activator (t-pa) into the lateral ventricle of psd rats, this significantly improved the stress-induced depression-like behavior,thus further validating the above results. |
2024-02-29 |
2024-03-03 |
rat |
| Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling-Leffle. Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences. 2024-02-27. PMID:38410450. |
extrapolation of cell-type results to brain regions reveals important patterns for schizophrenia with distinct subregions in the hippocampus and amygdala exhibiting the highest significance. |
2024-02-27 |
2024-03-02 |
mouse |
| Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling-Leffle. Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences. 2024-02-27. PMID:38410450. |
using functional mri connectivity from cases with schizophrenia and neurotypical controls, we identified brain networks that distinguished cases from controls that also confirmed involvement of the central and lateral amygdala, hippocampal body, and prefrontal cortex. |
2024-02-27 |
2024-03-02 |
mouse |
| Jennifer W Evans, Morgan C Graves, Allison C Nugent, Carlos A Zarat. Hippocampal volume changes after (R,S)-ketamine administration in patients with major depressive disorder and healthy volunteers. Scientific reports. vol 14. issue 1. 2024-02-24. PMID:38402253. |
the hippocampus and amygdala have been implicated in the pathophysiology and treatment of major depressive disorder (mdd). |
2024-02-24 |
2024-02-27 |
human |
| Max P Herzberg, Ashley N Nielsen, Rebecca Brady, Sydney Kaplan, Dimitrios Alexopoulos, Dominique Meyer, Jyoti Arora, J Philip Miller, Tara A Smyser, Deanna M Barch, Cynthia E Rogers, Barbara B Warner, Christopher D Smyser, Joan L Lub. Maternal prenatal social disadvantage and neonatal functional connectivity: Associations with psychopathology symptoms at age 12 months. Developmental psychology. 2024-02-22. PMID:38386382. |
this study extends this literature by investigating the relation of maternal prenatal social disadvantage (psd) to neonatal amygdala and hippocampus functional connectivity and whether socioeconomic-related alterations in functional connectivity subsequently predict behavior at age 12 months in a large, socioeconomically diverse sample ( |
2024-02-22 |
2024-02-24 |
Not clear |
| Orr Shahar, Alexander Botvinnik, Amit Shwartz, Elad Lerer, Peretz Golding, Alex Buko, Ethan Hamid, Dani Kahn, Miles Guralnick, Karin Blakolmer, Gilly Wolf, Amit Lotan, Leonard Lerer, Bernard Lerer, Tzuri Lifschyt. Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain. Molecular psychiatry. 2024-02-21. PMID:38378926. |
brain specimens (frontal cortex, hippocampus, amygdala, striatum) were assayed for the synaptic proteins, gap43, psd95, synaptophysin and sv2a, using western blots. |
2024-02-21 |
2024-02-23 |
mouse |
| Orr Shahar, Alexander Botvinnik, Amit Shwartz, Elad Lerer, Peretz Golding, Alex Buko, Ethan Hamid, Dani Kahn, Miles Guralnick, Karin Blakolmer, Gilly Wolf, Amit Lotan, Leonard Lerer, Bernard Lerer, Tzuri Lifschyt. Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain. Molecular psychiatry. 2024-02-21. PMID:38378926. |
after 11 days, psil and pme significantly increased gap43 in the frontal cortex (p = 0.019; p = 0.039 respectively) and hippocampus (p = 0.015; p = 0.027) and synaptophysin in the hippocampus (p = 0.041; p = 0.05) and amygdala (p = 0.035; p = 0.004). |
2024-02-21 |
2024-02-23 |
mouse |
| Orr Shahar, Alexander Botvinnik, Amit Shwartz, Elad Lerer, Peretz Golding, Alex Buko, Ethan Hamid, Dani Kahn, Miles Guralnick, Karin Blakolmer, Gilly Wolf, Amit Lotan, Leonard Lerer, Bernard Lerer, Tzuri Lifschyt. Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain. Molecular psychiatry. 2024-02-21. PMID:38378926. |
psil increased sv2a in the amygdala (p = 0.036) and pme did so in the hippocampus (p = 0.014). |
2024-02-21 |
2024-02-23 |
mouse |
| Orr Shahar, Alexander Botvinnik, Amit Shwartz, Elad Lerer, Peretz Golding, Alex Buko, Ethan Hamid, Dani Kahn, Miles Guralnick, Karin Blakolmer, Gilly Wolf, Amit Lotan, Leonard Lerer, Bernard Lerer, Tzuri Lifschyt. Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain. Molecular psychiatry. 2024-02-21. PMID:38378926. |
nested analysis of variance (anova) showed a significant increase in each of the 4 proteins over all brain areas for pme versus vehicle control, while significant psil effects were observed only in the hippocampus and amygdala and were limited to psd95 and sv2a. |
2024-02-21 |
2024-02-23 |
mouse |
| Jonas M Hebel, Michael Lanz, Thomas Malina, Stefan R G Stodieck, Michel Le Van Quye. Effects of midazolam on high-frequency oscillations in amygdala and hippocampus of epilepsy patients. Epilepsia. 2024-02-17. PMID:38366848. |
effects of midazolam on high-frequency oscillations in amygdala and hippocampus of epilepsy patients. |
2024-02-17 |
2024-02-19 |
Not clear |
| Christopher J E Denning, Lauren E Madory, Jessica N Herbert, Ryan A Cabrera, Karen K Szumlinsk. Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339206. |
relative to naïve controls, ma-experienced mice exhibited several changes in the expression of certain glutamate receptor-related proteins and their downstream effectors within the ventral and dorsal areas of the prefrontal cortex, the hippocampus, and the amygdala, many of which were sex-selective. |
2024-02-10 |
2024-02-12 |
mouse |
| Izabelle Dias Benfato, Ana Carolina Silvares Quintanilha, Jessica Salles Henrique, Melyssa Alves Souza, Barbara Dos Anjos Rosário, Jose Ivo Araújo Beserra Filho, Alessandra Mussi Ribeiro, Luciana Le Sueur Maluf, Camila Aparecida Machado de Oliveir. Long-term calorie restriction prevented memory impairment in middle-aged male mice and increased a marker of dna oxidative stress in hippocampal dentate gyrus. Neurobiology of learning and memory. 2024-02-09. PMID:38336097. |
in addition, immunohistochemistry targetingΔfosb (neuronal activity),brain-derived neurotrophic factor (bdnf) and thedna oxidative damage (8ohdg) in hippocampal subfields ca1, ca2, ca3, and dentate gyrus (dg), and in basolateral amygdala and striatum were performed. |
2024-02-09 |
2024-02-12 |
mouse |