| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaige Liu, Yue Qu, Bozhi Li, Ningxi Zeng, Gaolei Yao, Xiaofeng Wu, Hanfang Xu, Can Yan, Lili W. GRP94 in cerebrospinal fluid may contribute to a potential biomarker of depression: Based on proteomics. Journal of psychiatric research. vol 169. 2023-12-11. PMID:38081093. |
flx significantly increased neuronal numbers in dentate gyrus (dg) and ca3 regions of hippocampus. |
2023-12-11 |
2023-12-17 |
rat |
| Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in hilar mossy cells regulate excitatory transmission and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 50. 2023-12-08. PMID:38064513. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-12-08 |
2023-12-17 |
Not clear |
| Yu Dong, Zihan Lu, Tiantian Gao, Zhifeng Wei, Zhijie Ou, Zheng Shi, Jie She. A polypeptide derived from pilose antler ameliorates CUMS-induced depression-like behavior by SENP2-PLCβ4 signaling axis. European journal of pharmacology. 2023-12-06. PMID:38056617. |
neurogenesis in the dentate gyrus (dg) region of hippocampus was observed by immunofluorescence. |
2023-12-06 |
2023-12-10 |
Not clear |
| Kaitlyn E Dorst, Ryan A Senne, Anh H Diep, Antje R de Boer, Rebecca L Suthard, Heloise Leblanc, Evan A Ruesch, Angela Y Pyo, Sara Skelton, Lucas C Carstensen, Samantha Malmberg, Olivia P McKissick, John H Bladon, Steve Ramire. Hippocampal engrams generate variable behavioral responses and brain-wide network states. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-12-05. PMID:38050098. |
to address this, we optogenetically reactivated a fear engram in the dentate gyrus (dg) subregion of the hippocampus across three distinct contexts in male mice. |
2023-12-05 |
2023-12-10 |
mouse |
| Yanyi Ding, Long Li, Sinuo Wang, Yajun Cao, Minguang Yang, Yaling Dai, Huawei Lin, Jianhong Li, Yulu Liu, Zhifu Wang, Weilin Liu, Jing Ta. Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model. Biological research. vol 56. issue 1. 2023-12-02. PMID:38041203. |
impaired pattern separation occurs in the early stage of alzheimer's disease (ad), and hippocampal dentate gyrus (dg) neurogenesis participates in pattern separation. |
2023-12-02 |
2023-12-10 |
mouse |
| Etienne Aumont, Aurélie Bussy, Marc-André Bedard, Gleb Bezgin, Joseph Therriault, Melissa Savard, Jaime Fernandez Arias, Viviane Sziklas, Paolo Vitali, Nina Margherita Poltronetti, Vanessa Pallen, Emilie Thomas, Serge Gauthier, Eliane Kobayashi, Nesrine Rahmouni, Jenna Stevenson, Cecile Tissot, Mallar M Chakravarty, Pedro Rosa-Net. Hippocampal subfield associations with memory depend on stimulus modality and retrieval mode. Brain communications. vol 5. issue 6. 2023-11-30. PMID:38035364. |
we segmented the right and left hippocampi into (i) dentate gyrus and cornu ammonis 4 (dg/ca4); (ii) ca2 and ca3 (ca2/ca3); (iii) ca1; (iv) strata radiatum, lacunosum and moleculare; and (v) subiculum. |
2023-11-30 |
2023-12-10 |
human |
| Anbiao Wu, Jiyan Zhan. Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis. Journal of neuroinflammation. vol 20. issue 1. 2023-11-28. PMID:38012702. |
neuroinflammation has been reported to be involved in mdd through distinct neurobiological mechanisms, among which the dysregulation of neurogenesis in the dentate gyrus (dg) of the hippocampus (hpc) is receiving increasing attention. |
2023-11-28 |
2023-11-29 |
Not clear |
| Yan Cao, Pan Liu, Hongfei Bian, Sixuan Jin, Jiaqi Liu, Ning Yu, Huan Cui, Fengrun Sun, Xiaojing Qian, Wenying Qiu, Chao M. Reduced neurogenesis in human hippocampus with Alzheimer's disease. Brain pathology (Zurich, Switzerland). 2023-11-27. PMID:38012054. |
in this study, we observed a significant presence of neurogenic cells in the hippocampus's dentate gyrus (dg) region in 30 individuals, including 14 individuals diagnosed with ad-related neuropathological changes and the remaining 16 individuals without any neurological diseases. |
2023-11-27 |
2023-11-29 |
human |
| Matin Baghani, Arad Bolouri-Roudsari, Reyhaneh Askari, Abbas Haghparas. Orexin receptors in the hippocampal dentate gyrus modulated the restraint stress-induced analgesia in the animal model of chronic pain. Behavioural brain research. vol 459. 2023-11-25. PMID:37995966. |
since orexin neuropeptides are involved in pain modulation, and orexin neurons, primarily located in the lateral hypothalamus (lh), project to various hippocampal regions, such as the dentate gyrus (dg), the current study aimed to examine the role of orexin receptors within the dg region in the restraint sia in the animal model of chronic pain. |
2023-11-25 |
2023-11-28 |
rat |
| Isabel Calatayud-Baselga, Lucía Casares-Crespo, Carmina Franch-Ibáñez, José Guijarro-Nuez, Pascual Sanz, Helena Mir. Autophagy drives the conversion of developmental neural stem cells to the adult quiescent state. Nature communications. vol 14. issue 1. 2023-11-24. PMID:38001081. |
selective ablation of atg7, a critical gene for autophagosome formation, in radial glia-like nscs at early and late postnatal stages compromises the initial acquisition and maintenance of quiescence during the formation of the hippocampal dentate gyrus nsc niche. |
2023-11-24 |
2023-11-28 |
Not clear |
| Mingting Shao, Hang Yu, Vijayalakshmi Santhakumar, Jiandong Y. Antiepileptogenic and neuroprotective effect of mefloquine after experimental status epilepticus. Epilepsy research. vol 198. 2023-11-21. PMID:37989006. |
uniquely, parvalbumin expressing neurons in the hippocampal dentate gyrus appeared relatively resistant to early cell loss after se. |
2023-11-21 |
2023-11-29 |
rat |
| Dore Loef, Indira Tendolkar, Philip F P van Eijndhoven, Jeroen J M Hoozemans, Mardien L Oudega, Annemieke J M Rozemuller, Paul J Lucassen, Annemiek Dols, Anke A Dijkstr. Electroconvulsive therapy is associated with increased immunoreactivity of neuroplasticity markers in the hippocampus of depressed patients. Translational psychiatry. vol 13. issue 1. 2023-11-20. PMID:37981649. |
in rodents, electroconvulsive shocks increase proliferation and the expression of plasticity markers in the hippocampal dentate gyrus (dg), suggesting increased neurogenesis. |
2023-11-20 |
2023-11-29 |
human |
| Abigail C Toltin, Abdelmadjid Belkadi, Laura M Gamba, Muhammad M Hossai. The Preventive Effects of Salubrinal against Pyrethroid-Induced Disruption of Adult Hippocampal Neurogenesis in Mice. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958604. |
salubrinal prevented hippocampal er stress, as indicated by decreased levels of c/ebp-homologous protein (chop) and transcription factor 4 (atf4) and attenuated deltamethrin-induced reductions in brdu-, ki-67-, and dcx-positive cells in the dentate gyrus (dg) of the hippocampus. |
2023-11-14 |
2023-11-20 |
mouse |
| Selena Singh, Suzanna Becker, Thomas Trappenberg, Abraham Nune. Granule cells perform frequency-dependent pattern separation in a computational model of the dentate gyrus. Hippocampus. 2023-11-11. PMID:37950569. |
we aim to study, in a computational model of the hippocampal dentate gyrus (dg), the network and cellular mechanisms governing this putative "u"-shaped ps relationship. |
2023-11-11 |
2023-11-20 |
Not clear |
| Bingran Chen, Cheng Zhao, Haojie Zhu, Xu Lu, Huijun Liu, Qun Lu, Tao Zhu, Chao Huan. β-glucan, a specific immuno-stimulant, produces rapid antidepressant effects by stimulating ERK1/2-dependent synthesis of BDNF in the hippocampus. European journal of pharmacology. 2023-11-08. PMID:37939990. |
a decline in microglia in the dentate gyrus of the hippocampus has recently been described as an important mechanism for the progression of depression. |
2023-11-08 |
2023-11-20 |
mouse |
| Yasunori Takahashi, Ryota Ojiro, Risako Yamashita, Saori Shimizu, Natsuno Maeda, Xinyu Zou, Qian Tang, Shunsuke Ozawa, Gye-Hyeong Woo, Toshinori Yoshida, Makoto Shibutan. Suppression of neurogranin expression by disruption of epigenetic DNA methylation in hippocampal mature granule cells after developmental exposure to neurotoxicants in rats. Toxicology letters. 2023-11-05. PMID:37926403. |
we previously performed comprehensive analyses of genes hypermethylated promoter regions and downregulated transcripts in the hippocampal dentate gyrus (dg) of rats upon weaning at postnatal day (pnd) 21 after developmental exposure to 6-propyl-2-thiouracil (ptu), valproic acid, and glycidol (gly), all of which are known to show irreversible effects on hippocampal neurogenesis in adulthood on pnd 77. |
2023-11-05 |
2023-11-08 |
rat |
| Ziwei Gao, Chao Lu, Yaping Zhu, Yuxin Liu, Yuesong Lin, Wenming Gao, Liyuan Tian, Lei W. Merazin hydrate produces rapid antidepressant effect by activating CaMKII to promote neuronal activities and proliferation in hippocampus. Brain research. 2023-11-04. PMID:37924927. |
moreover, mh could not only significantly up-regulated the expressions of cfos, but also obviously increased the number of ki67 positive cells in hippocampal dentate gyrus (dg). |
2023-11-04 |
2023-11-08 |
mouse |
| Nikolai Malykhin, Wojciech Pietrasik, Kim Ngan Hoang, Yushan Huan. Contributions of hippocampal subfields and subregions to episodic memory performance in healthy cognitive aging. Neurobiology of aging. vol 133. 2023-11-01. PMID:37913626. |
in the present study we investigated whether hippocampal subfield (cornu ammonis 1-3, dentate gyrus, and subiculum) and anteroposterior hippocampal subregion (head,body, and tail) volumes can predict episodic memory function using high-field high resolution structural magnetic resonance imaging (mri). |
2023-11-01 |
2023-11-08 |
human |
| Nikolai Malykhin, Wojciech Pietrasik, Kim Ngan Hoang, Yushan Huan. Contributions of hippocampal subfields and subregions to episodic memory performance in healthy cognitive aging. Neurobiology of aging. vol 133. 2023-11-01. PMID:37913626. |
we found that the volume of the dentate gyrus subfield and posterior hippocampus (body) showed a significant direct effect on visuospatial memory performance; additionally, an indirect effect of age on visuospatial memory mediated through these hippocampal subfield/subregion was significant. |
2023-11-01 |
2023-11-08 |
human |
| Roya Homayouni, Kelsey L Canada, Samaah Saifullah, Da' Jonae Foster, Charlotte Thill, Naftali Raz, Ana M Daugherty, Noa Ofe. Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis. Hippocampus. 2023-10-26. PMID:37881160. |
it is comprised of cytoarchitectonically distinct subfields: dentate gyrus (dg), cornu ammonis sectors (ca) 1-4, and subiculum, each of which may be differentially susceptible to neurodevelopmental and neurodegenerative mechanisms. |
2023-10-26 |
2023-11-08 |
human |