| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
the present study demonstrated for the first time that acute as well as subchronic (4\xe2\x80\xafdays) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3\xe2\x80\xafmg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the \xce\xb2-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-03-06 |
rat |
| Jae Soon Kang, Ji Hyeong Baek, Mi Yeong Song, Naveed Ur Rehman, Hye Jin Chung, Dong Kun Lee, Dae Young Yoo, Hyun Joon Ki. Long-term exposure changes the environmentally relevant bis(2-ethylhexyl) phthalate to be a neuro-hazardous substance disrupting neural homeostasis in emotional and cognitive functions. Environmental pollution (Barking, Essex : 1987) vol issue 2023 36870594 |
long-term dehp ingestion induced collapse of glutamate (glu) and glutamine (gln) homeostasis as a result of disruption of the glu-gln cycle in the medial prefrontal cortex and hippocampus. |
2023-03-04 |
2023-03-06 |
mouse |
| Emerson de Oliveira Ferreira, J\\xc3\\xa9ssica Maria Pessoa Gomes, Kelly Rose Tavares Neves, Francisco Arnaldo Viana Lima, Glauce Socorro de Barros Viana, Geanne Matos de Andrad. Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice. Behavioural pharmacology vol issue 2023 36853856 |
in the present study, we examined the effects of maternal treatment with apz (10\xe2\x80\x89mg/kg) in juvenile mice prenatally exposed to vpa on neurodevelopmental behaviors, social interactions, communication, and working memory, as well as synaptophysin (syp), synaptosomal-associated protein, 25\xe2\x80\x89kda (snap-25) and microtubule-associated protein 2 (map-2) expression in the medial prefrontal cortex (mpfc) and cell viability in the hippocampus. |
2023-02-28 |
2023-03-06 |
mouse |
| Thays Brenner Santos, Juliana Carlota Kramer-Soares, Maria Gabriela Menezes Oliveir. Contextual fear conditioning with a time interval induces CREB phosphorylation in the dorsal hippocampus and amygdala nuclei that depend on prelimbic cortex activity. Hippocampus vol issue 2023 36847108 |
for this, we observed in wistar rats the effect of pre-training pl inactivation by muscimol in creb (camp response element-binding protein) phosphorylation, which is essential for memory consolidation, in subdivisions of the medial prefrontal cortex (mpfc), hippocampus, and amygdala 3\xc2\xa0h after the training in the contextual fear conditioning (cfc) or cfc with 5-s interval (cfc-5s), fear associations without or with an interval between the cs and us, respectively. |
2023-02-27 |
2023-03-06 |
rat |
| Shi Yan, Chang Xu, Mengli Yang, Huiqiang Zhang, Ye Cheng, Zeping Xue, Zecong He, Tiantian Wang, Shangying Bai, Gang Wang, Jianping Wu, Zhiqian Tong, Xiang Ca. The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress. Neuropharmacology vol issue 2023 36849038 |
in this study, we observed that agmat expression increased in the ventral hippocampus rather than in the medial prefrontal cortex in the chronic restraint stress (crs) animal model of depression. |
2023-02-27 |
2023-03-06 |
rat |
| Phillip M Muza, Daniel Bush, Marta P\\xc3\\xa9rez-Gonz\\xc3\\xa1lez, Ines Zouhair, Karen Cleverley, Miriam L Sopena, Rifdat Aoidi, Steven J West, Mark Good, Victor L J Tybulewicz, Matthew C Walker, Elizabeth M C Fisher, Pishan Chan. Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. iScience vol 26 issue 2 2023 36818290 |
in this study, we investigated neuronal dysfunction in the dp(10)2yey mouse and report spatial memory impairment and anxiety-like behavior alongside altered neural activity in the medial prefrontal cortex (mpfc) and hippocampus (hpc). |
2023-02-23 |
2023-03-06 |
mouse |
| Shang Lin Tommy Lee, Brian Timmerman, Riley Pflomm, Nikita Roy, Mahathi Kumar, Etan J Marku. Sequential order spatial memory in male rats: Characteristics and impact of medial prefrontal cortex and hippocampus disruption. Neurobiology of learning and memory vol issue 2023 36822465 |
sequential order spatial memory in male rats: characteristics and impact of medial prefrontal cortex and hippocampus disruption. |
2023-02-23 |
2023-03-06 |
rat |
| Michael Murack, Kevin B Smith, Olivia H Traynor, Atiqa F Pirwani, Sarah K Gostlin, Taha Mohamed, Despina A Tata, Claude Messier, Nafissa Ismai. Environmental Enrichment Alters LPS-induced changes in BDNF and PSD-95 Expressions During Puberty. Brain research vol issue 2023 36801452 |
male and female ee mice displayed greater bdnf and psd-95 expressions in the medial prefrontal cortex and hippocampus compared to socially housed and deprived housed mice. |
2023-02-21 |
2023-03-06 |
mouse |
| Michael Murack, Kevin B Smith, Olivia H Traynor, Atiqa F Pirwani, Sarah K Gostlin, Taha Mohamed, Despina A Tata, Claude Messier, Nafissa Ismai. Environmental Enrichment Alters LPS-induced changes in BDNF and PSD-95 Expressions During Puberty. Brain research vol issue 2023 36801452 |
interestingly, lps-treated mice housed in deprived conditions displayed unexpected increases in bdnf and psd-95 expressions throughout the medial prefrontal cortex and hippocampus. |
2023-02-21 |
2023-03-06 |
mouse |
| Alexander P Schwarz, Veronika A Nikitina, Darya U Krytskaya, Ksenia P Shcherbakova, Alexander N Trofimo. Reference gene expression stability within the rat brain under mild intermittent ketosis induced by supplementation with medium-chain triglycerides. PloS one vol 18 issue 2 2023 36757952 |
the mrna expression of 9 housekeeping genes (actb, b2m, gapdh, hprt1, pgk1, ppia, rpl13a, sdha, ywhaz) in the medial prefrontal cortex, dorsal and ventral hippocampus was measured by rt-qpcr. |
2023-02-09 |
2023-03-06 |
rat |
| Alexander P Schwarz, Veronika A Nikitina, Darya U Krytskaya, Ksenia P Shcherbakova, Alexander N Trofimo. Reference gene expression stability within the rat brain under mild intermittent ketosis induced by supplementation with medium-chain triglycerides. PloS one vol 18 issue 2 2023 36757952 |
the most stably expressed reference genes were found to be ppia, actb, and rpl13a in the medial prefrontal cortex; rpl13a, ywhaz, and pgk1 in the dorsal hippocampus; ywhaz, sdha, and ppia in the ventral hippocampus. |
2023-02-09 |
2023-03-06 |
rat |
| Xiao-Bo Wu, Qian Zhu, Ming-Hui Gao, Sheng-Xiang Yan, Pan-Yang Gu, Peng-Fei Zhang, Meng-Lin Xu, Yong-Jing Ga. Excitatory projections from the prefrontal cortex to nucleus accumbens core D1-MSNs and kappa opioid receptor modulate itch-related scratching behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience vol issue 2023 36653189 |
excitatory afferents from the medial prefrontal cortex (mpfc), amygdala, and hippocampus are crucial in tuning the activity of dopamine receptor d1- and d2-expressing medium spiny neurons (drd1- and drd2-msns) in the nac. |
2023-01-18 |
2023-01-30 |
mouse |
| Kati L Healey, Amelia Bell, Michael D Scofield, H S Swartzwelde. Adolescent intermittent ethanol exposure reduces astrocyte-synaptic proximity in the adult medial prefrontal cortex in rats: Reversal by gabapentin. Addiction neuroscience vol 4 issue 2023 36643603 |
the medial prefrontal cortex (mpfc) and dorsal hippocampus are critical for executive function and memory and are especially vulnerable to adolescent ethanol exposure. |
2023-01-16 |
2023-01-30 |
rat |
| Jian Ruan, Xiuhua Hu, Yuehong Liu, Zhao Han, Qingwei Rua. Vulnerability to chronic stress and the phenotypic heterogeneity of presbycusis with subjective tinnitus. Frontiers in neuroscience vol 16 issue 2023 36620444 |
chronic audiogenic stressors, including aging accompanying ontological diseases, cumulative noise exposure, and ototoxic drugs as well as tinnitus, activate the hpa axis and sam directly and indirectly by the amygdala, promoting allostatic load and maladaptive neuroplasticity in the auditory system and other vulnerable brain regions, such as the hippocampus, amygdala, and medial prefrontal cortex (mpfc). |
2023-01-09 |
2023-01-30 |
Not clear |
| Satoshi Deyama, Shun Aoki, Rinako Sugie, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaned. Intranasal Administration of Resolvin E1 Produces Antidepressant-Like Effects via BDNF/VEGF-mTORC1 Signaling in the Medial Prefrontal Cortex. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics vol issue 2023 36622634 |
additionally, local infusion of rve1 into the medial prefrontal cortex (mpfc) or dorsal hippocampal dentate gyrus (dg) produces antidepressant-like effects. |
2023-01-09 |
2023-01-30 |
mouse |
| Gloria G Parras, Roc\\xc3\\xado Leal-Campanario, Juan C L\\xc3\\xb3pez-Ramos, Agn\\xc3\\xa8s Gruart, Jos\\xc3\\xa9 M Delgado-Garc\\xc3\\xad. Functional properties of eyelid conditioned responses and involved brain centers. Frontiers in behavioral neuroscience vol 16 issue 2022 36570703 |
here, we address specifically the functional roles of three brain structures (red nucleus, cerebellar interpositus nucleus, and motor cortex) mainly involved in the acquisition and performance of eyelid conditioned responses and three other brain structures (hippocampus, medial prefrontal cortex, and claustrum) related to non-motor aspects of the acquisition process. |
2022-12-26 |
2023-01-30 |
Not clear |
| Ana Jakovljevic, Gorana Agatonovic, Dubravka Aleksic, Milan Aksic, Gebhard Reiss, Eckart F\\xc3\\xb6rster, Antonios Stamatakis, Igor Jakovcevski, Joko Poleksi. The impact of early life maternal deprivation on the perineuronal nets in the prefrontal cortex and hippocampus of young adult rats. Frontiers in cell and developmental biology vol 10 issue 2022 36518543 |
to experimentally address the impact of early life stress on the pnns and pv+ interneurons in the medial prefrontal cortex and dorsal hippocampus in rats, we employed a 24\xc2\xa0h maternal deprivation protocol. |
2022-12-15 |
2023-01-30 |
rat |
| R Oliver Goral, Kathryn M Harper, Briana J Bernstein, Sydney A Fry, Patricia W Lamb, Sheryl S Moy, Jesse D Cushman, Jerrel L Yake. Loss of GABA co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions. Frontiers in behavioral neuroscience vol 16 issue 2022 36505727 |
loss of gaba co-transmission from cholinergic neurons impairs behaviors related to hippocampal, striatal, and medial prefrontal cortex functions. |
2022-12-12 |
2023-01-30 |
Not clear |
| Myrcea A de S Tilger, Renan B Gaiardo, Suzete M Cerutt. Inactivation of the dorsal CA1 hippocampus impairs the consolidation of discriminative avoidance memory by modulating the intrinsic and extrinsic hippocampal circuitry. Journal of chemical neuroanatomy vol issue 2022 36496001 |
differential camp-response-element-binding protein 1 (creb-1) expression in the dorsal and ventral ca1 and ca3 of the hippocampus (dca1, dca3, vca1, and vca3), dorsal dentate gyrus (ddg), and infralimbic (il) and prelimbic (prl) regions of the medial prefrontal cortex was also assessed to investigate the molecular changes associated with the consolidation or retrieval of episodic-like memory and anxiety. |
2022-12-10 |
2023-01-30 |
rat |
| FengYing Lu, WenJing Yang, Jiang Qi. Neural bases of motivated forgetting of autobiographical memories. Cognitive neuroscience vol issue 2022 36409182 |
attempting to exclude negative autobiographical memories from awareness was associated with increased activity in the right mfg, superior frontal gyrus (sfg), and inferior frontal gyrus (ifg), while reduced activity was observed in the bilateral brodmann areas ba18 and ba19, bilateral medial prefrontal cortex (mpfc), bilateral precuneus, bilateral post cingulate cortex (pcc), the left parahippocampus, and the left hippocampus. |
2022-11-21 |
2023-01-30 |
human |