| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yann Vanrobaeys, Zeru J Peterson, Emily N Walsh, Snehajyoti Chatterjee, Li-Chun Lin, Lisa C Lyons, Thomas Nickl-Jockschat, Ted Abe. Spatial transcriptomics reveals unique gene expression changes in different brain regions after sleep deprivation. Nature communications. vol 14. issue 1. 2023-11-05. PMID:37925446. |
we find that sleep deprivation induced pronounced differences in gene expression across the brain, with the greatest changes in the hippocampus, neocortex, hypothalamus, and thalamus. |
2023-11-05 |
2023-11-08 |
mouse |
| Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.). vol 165. 2023-03-04. PMID:36869551. |
in hypothalamus and hippocampus, clock (bmal1 and clock) and tight junction (ocln and tjp2) genes were improved by prebiotics, and corticotropin-releasing hormone receptor genes, crf1 and crf2, were also significantly regulated for mitigation of depression and anxiety caused by sleep deprivation. |
2023-03-04 |
2023-08-14 |
mouse |
| Yann Vanrobaeys, Zeru J Peterson, Emily N Walsh, Snehajyoti Chatterjee, Li-Chun Lin, Lisa C Lyons, Thomas Nickl-Jockschat, Ted Abe. Spatial transcriptomics reveals unique gene expression changes in different brain regions after sleep deprivation. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36712009. |
we find that sleep deprivation induced pronounced differences in gene expression across the brain, with the greatest changes in the hippocampus, neocortex, hypothalamus, and thalamus. |
2023-01-30 |
2023-08-14 |
Not clear |
| Rong-Jin Lin, Xiao-Feng Da. Sleep deprivation affects sex hormones secretion by regulating the expression of the circadian clock gene in the hypothalamus and pituitary via the PI3K/Akt signaling pathway in pregnant rats. Sheng li xue bao : [Acta physiologica Sinica]. vol 74. issue 4. 2022-08-22. PMID:35993204. |
sleep deprivation affects sex hormones secretion by regulating the expression of the circadian clock gene in the hypothalamus and pituitary via the pi3k/akt signaling pathway in pregnant rats. |
2022-08-22 |
2023-08-14 |
rat |
| Darrell Eacret, Crystal Lemchi, Jasmine I Caulfield, Sonia A Cavigelli, Sigrid C Veasey, Julie A Blend. Chronic Sleep Deprivation Blocks Voluntary Morphine Consumption but Not Conditioned Place Preference in Mice. Frontiers in neuroscience. vol 16. 2022-03-07. PMID:35250468. |
the css paradigm did not increase corticosterone levels or depressive-like behavior after a single sleep deprivation session but did increase expression of iba1, which typically reflects microglial activation, in the hypothalamus after 4 weeks of css. |
2022-03-07 |
2023-08-13 |
mouse |
| Thaysa Kelly Barbosa Vieira, Myra Jurema da Rocha Leão, Luciana Xavier Pereira, Laryssa Cristina Alves da Silva, Bruno Batista Pereira da Paz, Ricardo Jansen Santos Ferreira, Christiane Cavalcante Feitoza, Ana Kelly Fernandes Duarte, Amanda Karine Barros Ferreira Rodrigues, Aline Cavalcanti de Queiroz, Karol Fireman de Farias, Bruna Del Vechio Koike, Carolinne de Sales Marques, Carlos Alberto de Carvalho Frag. Correlation between circadian rhythm related genes, type 2 diabetes, and cancer: Insights from metanalysis of transcriptomics data. Molecular and cellular endocrinology. vol 526. 2021-10-07. PMID:33610641. |
first, we detected downregulated and upregulated degs in mouse cortex and hypothalamus samples of mice with sleep deprivation. |
2021-10-07 |
2023-08-13 |
mouse |
| Shuang Hu, Pengxiang Li, Rong Zhang, Xuan Liu, Shougang We. Integrated metabolomics and proteomics analysis reveals energy metabolism disorders in the livers of sleep-deprived mice. Journal of proteomics. vol 245. 2021-08-10. PMID:34089895. |
metabolites and proteins in serum, urine and hypothalamus do not entirely reflect the effects of sleep deprivation on the whole body. |
2021-08-10 |
2023-08-13 |
mouse |
| Bruna Visniauskas, Priscila S R Simões, Fernanda M Dalio, Maria D G Naffah-Mazzacoratti, Vitor Oliveira, Sergio Tufik, Jair R Chaga. Sleep deprivation changes thimet oligopeptidase (THOP1) expression and activity in rat brain. Heliyon. vol 5. issue 11. 2020-10-01. PMID:31828230. |
in the striatum and hypothalamus, thop1 activity decreased following sleep deprivation and a recovery period. |
2020-10-01 |
2023-08-13 |
rat |
| Karim Fifel, Johanna H Meijer, Tom Deboe. Long-term effects of sleep deprivation on neuronal activity in four hypothalamic areas. Neurobiology of disease. vol 109. issue Pt A. 2018-06-25. PMID:29017795. |
our data indicate also that measuring electroencephalographic slow wave activity underestimates the amount of time that the hypothalamus requires to recover from episodes of sleep deprivation. |
2018-06-25 |
2023-08-13 |
rat |
| Danilo Alves Moraes, Daniel Paulino Venancio, Deborah Sucheck. Sleep deprivation alters energy homeostasis through non-compensatory alterations in hypothalamic insulin receptors in Wistar rats. Hormones and behavior. vol 66. issue 5. 2015-11-17. PMID:25304978. |
rats subjected to paradoxical sleep deprivation (psd) exhibit feeding and metabolic alterations, both of which are regulated by the communication between peripheral signals and the hypothalamus. |
2015-11-17 |
2023-08-13 |
rat |
| Anja C Peters, Jens Blechert, Philipp G Sämann, Ines Eidner, Michael Czisch, Victor I Spoormake. One night of partial sleep deprivation affects habituation of hypothalamus and skin conductance responses. Journal of neurophysiology. vol 112. issue 6. 2015-06-26. PMID:24920020. |
one night of partial sleep deprivation affects habituation of hypothalamus and skin conductance responses. |
2015-06-26 |
2023-08-13 |
Not clear |
| I V Romanova, A L Mikhrin. [Participation of Agouti related peptide in machanisms of wakefulness-sleep cycle regulation]. Fiziologiia cheloveka. vol 39. issue 6. 2014-12-31. PMID:25509169. |
immunohistochemical study in rats wistar rats demonstrates significant changes agrp optical density in the neurons of arcuate hypothalamic nucleus as well as in processes in the hypothalamus and nucleus accumbens after the 6 hours of sleep deprivation (increase) and after 2 hours of post-deprivative sleep (decrease). |
2014-12-31 |
2023-08-13 |
human |
| Liye Wang, Yuehan Song, Feng Li, Yan Liu, Jie Ma, Meng Mao, Fengzhi Wu, Ying Wu, Sinai Li, Binghe Guan, Xiaolan Li. Effects of Wen Dan Tang on insomnia-related anxiety and levels of the brain-gut peptide Ghrelin. Neural regeneration research. vol 9. issue 2. 2014-09-10. PMID:25206802. |
wen dan tang significantly reduced insomnia-related anxiety and prevented ghrelin level decreases following sleep deprivation, especially in the hypothalamus. |
2014-09-10 |
2023-08-13 |
rat |
| Md Aftab Alam, Sunil Kumar, Dennis McGinty, Md Noor Alam, Ronald Szymusia. Neuronal activity in the preoptic hypothalamus during sleep deprivation and recovery sleep. Journal of neurophysiology. vol 111. issue 2. 2014-08-26. PMID:24174649. |
neuronal activity in the preoptic hypothalamus during sleep deprivation and recovery sleep. |
2014-08-26 |
2023-08-12 |
rat |
| Won Sub Kang, Hae Jeong Park, Joo-Ho Chung, Jong Woo Ki. REM sleep deprivation increases the expression of interleukin genes in mice hypothalamus. Neuroscience letters. vol 556. 2014-02-10. PMID:24080377. |
rem sleep deprivation increases the expression of interleukin genes in mice hypothalamus. |
2014-02-10 |
2023-08-12 |
mouse |
| Noah T Ashley, James C Walton, Achikam Haim, Ning Zhang, Laura A Prince, Allison M Fruchey, Rebecca A Lieberman, Zachary M Weil, Ulysses J Magalang, Randy J Nelso. Sleep deprivation attenuates endotoxin-induced cytokine gene expression independent of day length and circulating cortisol in male Siberian hamsters (Phodopus sungorus). The Journal of experimental biology. vol 216. issue Pt 14. 2014-01-21. PMID:23531821. |
among lps-challenged hamsters, sleep deprivation reduced il-1 mrna levels in liver and hypothalamus, but not tnf. |
2014-01-21 |
2023-08-12 |
Not clear |
| Kanae Obukuro, Mizuki Nobunaga, Moeko Takigawa, Hiroshi Morioka, Akinori Hisatsune, Yoichiro Isohama, Hiroaki Shimokawa, Masato Tsutsui, Hiroshi Katsuk. Nitric oxide mediates selective degeneration of hypothalamic orexin neurons through dysfunction of protein disulfide isomerase. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 31. 2013-10-17. PMID:23904594. |
interestingly, sleep deprivation for 7 consecutive days induced a selective decrease of orexin-ir neurons, which was preceded by aggregate formation in orexin-ir neurons and an increase in s-nitrosated pdi in the hypothalamus. |
2013-10-17 |
2023-08-12 |
mouse |
| b' Raymond Cespuglio, Donia Amrouni, Anne Meiller, Alain Buguet, Sabine Gautier-Sauvign\\xc3\\xa. Nitric oxide in the regulation of the sleep-wake states. Sleep medicine reviews. vol 16. issue 3. 2012-08-16. PMID:22406306.' |
in the basal hypothalamus, the no/nnos production further contributes to the rem sleep rebound that takes place after a sleep deprivation (sd). |
2012-08-16 |
2023-08-12 |
mouse |
| Javier Franco-Pérez, Paola Ballesteros-Zebadúa, Edith A Fernández-Figueroa, Isabel Ruiz-Olmedo, Pablo Reyes-Grajeda, Carlos Pa. Sleep deprivation and sleep recovery modifies connexin36 and connexin43 protein levels in rat brain. Neuroreport. vol 23. issue 2. 2012-04-12. PMID:22158029. |
therefore, we examined in adult male wistar rats whether protein levels of connexin36 and connexin43 change in pons, hypothalamus, and frontal cortex after 24 h of total sleep deprivation and 4 h of sleep recovery. |
2012-04-12 |
2023-08-12 |
rat |
| Javier Franco-Pérez, Paola Ballesteros-Zebadúa, Edith A Fernández-Figueroa, Isabel Ruiz-Olmedo, Pablo Reyes-Grajeda, Carlos Pa. Sleep deprivation and sleep recovery modifies connexin36 and connexin43 protein levels in rat brain. Neuroreport. vol 23. issue 2. 2012-04-12. PMID:22158029. |
western blot revealed that total sleep deprivation significantly decreases the levels of connexin36 in the hypothalamus and this decrease maintains after sleep recovery. |
2012-04-12 |
2023-08-12 |
rat |