| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Akiyama, S Takino, Y Sugano, T Yamada, A Nakata, T Miura, M Fukumoto, H Yamashir. EFFECT OF SEASONAL CHANGES ON TESTICULAR MORPHOLOGY AND THE EXPRESSION OF CIRCADIAN CLOCK GENES IN JAPANESE WOOD MICE (APODEMUS SPECIOSUS). Journal of biological regulators and homeostatic agents. vol 29. issue 3. 2015-11-16. PMID:26403397. |
when an increase in testicular activity was observed indicating the onset of the reproductive season, the mean day length was approximately 1113 h. the expression of the circadian clock genes bmal1 and cry1 in the hypothalamus and testes during the reproductive season was significantly higher than that of the same genes during the transitional season. |
2015-11-16 |
2023-08-13 |
mouse |
| M Akiyama, S Takino, Y Sugano, T Yamada, A Nakata, T Miura, M Fukumoto, H Yamashir. EFFECT OF SEASONAL CHANGES ON TESTICULAR MORPHOLOGY AND THE EXPRESSION OF CIRCADIAN CLOCK GENES IN JAPANESE WOOD MICE (APODEMUS SPECIOSUS). Journal of biological regulators and homeostatic agents. vol 29. issue 3. 2015-11-16. PMID:26403397. |
out of the four examined genes, cry1 had the highest expression level in both the hypothalamus and testes throughout the year, followed by bmal1, per1, and clock. |
2015-11-16 |
2023-08-13 |
mouse |
| Tomoko Ikeno, Randy J Nelso. Acute melatonin treatment alters dendritic morphology and circadian clock gene expression in the hippocampus of Siberian hamsters. Hippocampus. vol 25. issue 2. 2015-09-16. PMID:25160468. |
in the hypothalamus, melatonin treatment did not alter period1 and bmal1 expression. |
2015-09-16 |
2023-08-13 |
Not clear |
| Y Wang, J T Ding, H M Yang, W Cao, Y B L. The effect of new monochromatic light regimes on egg production and expression of the circadian gene BMAL1 in pigeons1. Poultry science. vol 94. issue 5. 2015-08-06. PMID:25701204. |
expression of bmal1 in the hypothalamus was unaffected by the light regime but was greater in the pituitary of females exposed to red light (p = 0.046) and in the pituitary of males exposed to the control white light (p = 0.059). |
2015-08-06 |
2023-08-13 |
pigeon |
| Amit K Trivedi, Jayant Kumar, Sangeeta Rani, Vinod Kuma. Annual life history-dependent gene expression in the hypothalamus and liver of a migratory songbird: insights into the molecular regulation of seasonal metabolism. Journal of biological rhythms. vol 29. issue 5. 2015-06-29. PMID:25252711. |
the mrna levels of circadian genes involved in metabolism (bmal1, clock, npas2, rorα, and rev-erbα) and of genes that encode for proteins/enzymes involved in the regulation of glucose (sirt1, foxo1, glut1, and pygl) and lipids (hmg-coa; pparα, pparγ; fasn and acaca) showed lhs-dependent changes in their light-dark expression patterns in the hypothalamus and liver. |
2015-06-29 |
2023-08-13 |
Not clear |
| P Gilun, S Stefanczyk-Krzymowska, M Romerowicz-Misielak, A Tabecka-Lonczynska, F Przekop, M Koziorowsk. Carbon monoxide-mediated humoral pathway for the transmission of light signal to the hypothalamus. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 64. issue 6. 2014-09-04. PMID:24388891. |
the expression of clock genes (per1, per2, cry1, cry2, rev-erb α and rev-erb β) and the genes of their regulators (bmal1, npas2, clock, ror β) was estimated in two hypothalamic structures involved in the reception and transmission of light signal (the preoptic area (pa) and dorsal hypothalamus (dh)). |
2014-09-04 |
2023-08-12 |
Not clear |
| Stephen R Williams, Deborah Zies, Sureni V Mullegama, Michael S Grotewiel, Sarah H Else. Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity. American journal of human genetics. vol 90. issue 6. 2012-08-23. PMID:22578325. |
data further show that haploinsufficiency of rai1 and rai1 in sms fibroblasts and the mouse hypothalamus, respectively, results in the transcriptional dysregulation of the circadian clock and causes altered expression and regulation of multiple circadian genes, including per2, per3, cry1, bmal1, and others. |
2012-08-23 |
2023-08-12 |
mouse |
| Marcos A López Patiño, Arnau Rodríguez-Illamola, Marta Conde-Sieira, José L Soengas, Jesús M Mígue. Daily rhythmic expression patterns of clock1a, bmal1, and per1 genes in retina and hypothalamus of the rainbow trout, Oncorhynchus mykiss. Chronobiology international. vol 28. issue 5. 2011-11-09. PMID:21721853. |
then, retina and hypothalamus were collected from animals kept under ld conditions or constant darkness (dd) for 24 h. real-time quantitative reverse transcriptase-polymerase chain reaction (rt-pcr) assays were performed to quantify expression of the core circadian genes clock1a, bmal1, and per1 as representative members of the circadian oscillator. |
2011-11-09 |
2023-08-12 |
Not clear |
| Marcos A López Patiño, Arnau Rodríguez-Illamola, Marta Conde-Sieira, José L Soengas, Jesús M Mígue. Daily rhythmic expression patterns of clock1a, bmal1, and per1 genes in retina and hypothalamus of the rainbow trout, Oncorhynchus mykiss. Chronobiology international. vol 28. issue 5. 2011-11-09. PMID:21721853. |
however, gene expression peaked in the rainbow trout hypothalamus with a 3-h (clock1a and bmal1) or 6-h (per1) delay relative to that observed in the retina, the latter showing highest expression levels at zeitgeber times 9 (zt9) for clock1a and bmal1, and at zt21 for per1. |
2011-11-09 |
2023-08-12 |
Not clear |
| Marcos A López Patiño, Arnau Rodríguez-Illamola, Marta Conde-Sieira, José L Soengas, Jesús M Mígue. Daily rhythmic expression patterns of clock1a, bmal1, and per1 genes in retina and hypothalamus of the rainbow trout, Oncorhynchus mykiss. Chronobiology international. vol 28. issue 5. 2011-11-09. PMID:21721853. |
daily rhythmic expression patterns of clock1a, bmal1, and per1 genes in retina and hypothalamus of the rainbow trout, oncorhynchus mykiss. |
2011-11-09 |
2023-08-12 |
Not clear |
| Shelley A Tischkau, Rebecca E Howell, Jason R Hickok, Stacey L Krager, Janice M Bah. The luteinizing hormone surge regulates circadian clock gene expression in the chicken ovary. Chronobiology international. vol 28. issue 1. 2011-04-26. PMID:21182400. |
the authors first examined the 24-h expression patterns of the avian circadian clock genes of bmal1, cry1, and per2 in primary oscillatory tissues (hypothalamus and pineal) as well as peripheral tissues (liver and ovary). |
2011-04-26 |
2023-08-12 |
rat |
| Cathy A Wyse, Andrew N Cooga. Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain. Brain research. vol 1337. 2010-08-25. PMID:20382135. |
we report novel rhythmic expression of clock and bmal1 in a number of extra-scn sites in the young mouse brain, including the hippocampus, amygdala and the paraventricular, arcuate and dorsomedial nuclei of the hypothalamus. |
2010-08-25 |
2023-08-12 |
mouse |
| Ivette Caldelas, Belén González, Rodrigo Montúfar-Chaveznava, Robyn Hudso. Endogenous clock gene expression in the suprachiasmatic nuclei of previsual newborn rabbits is entrained by nursing. Developmental neurobiology. vol 69. issue 1. 2009-04-15. PMID:19023860. |
we now report that in newborn pups the suprachiasmatic nuclei of the hypothalamus (scn; the main circadian pacemaker in mammals) show endogenous 24-h rhythmicity in the expression of the clock genes per1, per2, and bmal1. |
2009-04-15 |
2023-08-12 |
rabbit |
| Patrick M Fuller, Jun Lu, Clifford B Sape. Differential rescue of light- and food-entrainable circadian rhythms. Science (New York, N.Y.). vol 320. issue 5879. 2008-06-02. PMID:18497298. |
injection of a viral vector containing the bmal1 gene into the suprachiasmatic nuclei of the hypothalamus restored light-entrainable, but not food-entrainable, circadian rhythms. |
2008-06-02 |
2023-08-12 |
mouse |
| I Caldelas, D Tejadilla, B González, R Montúfar, R Hudso. Diurnal pattern of clock gene expression in the hypothalamus of the newborn rabbit. Neuroscience. vol 144. issue 2. 2007-03-28. PMID:17055660. |
profiles in the expression of the clock genes per1, per2, cry1 and bmal1 were determined using in situ hybridization in brain sections through the hypothalamus at the level of the scn. |
2007-03-28 |
2023-08-12 |
rabbit |