| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiang-Ning He, Wei-Dan Jiang, Pei Wu, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Sheng-Yao Kuang, Ling Tang, Shu-Wei Li, Lin Feng, Xiao-Qiu Zho. Aflatoxin B1 inhibited the development of primary myoblasts of grass carp (Ctenopharyngodon idella) by degrading extracellular matrix. Ecotoxicology and environmental safety. vol 276. 2024-04-16. PMID:38626608. |
as a result, our findings suggested that afb1 damaged the cell morphology, induced oxidative damage and apoptosis, degraded ecm components, in turn inhibiting myoblast development by activating the p38mapk/urokinase-type plasminogen activator (upa)/matrix metalloproteinase (mmps)/extracellular matrix (ecm) signaling pathway. |
2024-04-16 |
2024-04-19 |
cat |
| Yingxin Lu, Ying Huang, Jiyu Jin, Jiahui Yu, Wei Lu, Shulei Zh. Design, synthesis, and biological evaluation of cathepsin B cleavage albumin-binding SN38 prodrug in breast cancer. Bioorganic chemistry. vol 147. 2024-04-15. PMID:38621338. |
histological immunohistochemical analyses further illuminate the multifaceted impact of our prodrug, showcasing elevated levels of apoptosis, downregulated expression of matrix metalloproteinases, and inhibition of angiogenesis, all critical factors contributing to the anti-metastatic effect observed. |
2024-04-15 |
2024-04-18 |
human |
| Hang Lv, Peiran Liu, Hai Hu, Xiaodong Li, Pengfei L. MiR-98-5p plays suppressive effects on IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting CASP3. Journal of orthopaedic surgery and research. vol 19. issue 1. 2024-04-13. PMID:38615043. |
this study aims to explore how mir-98-5p affects osteoarthritis, focusing on its role in chondrocyte inflammation, apoptosis, and extracellular matrix (ecm) degradation. |
2024-04-13 |
2024-04-16 |
Not clear |
| Valentina Fustaino, Giuliana Papoff, Francesca Ruberti, Giovina Rubert. Co-Expression Network Analysis Unveiled lncRNA-mRNA Links Correlated to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Resistance and/or Intermediate Epithelial-to-Mesenchymal Transition Phenotypes in a Human Non-Small Cell Lung Cancer Cellular Model System. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612674. |
processes enriched in the selected modules included rho (a, b, c) gtpase and regulatory signaling pathways, apoptosis, inflammatory and interleukin signaling pathways, cell adhesion, cell migration, cell and extracellular matrix organization, metabolism, and lipid metabolism. |
2024-04-13 |
2024-04-15 |
human |
| Haizhu Gao, Zhongxin Li, Lijun Gan, Xueying Che. The Role and Potential Mechanisms of Rehabilitation Exercise Improving Cardiac Remodeling. Journal of cardiovascular translational research. 2024-04-01. PMID:38558377. |
exercise training can mitigate cardiomyocyte apoptosis, reduce extracellular matrix deposition and fibrosis, promote angiogenesis, and regulate inflammatory response to improve cardiac remodeling. |
2024-04-01 |
2024-04-04 |
Not clear |
| Ieva Vanaga, Oksana Kolesova, Aleksandrs Kolesovs, Gunta Sture, Elvira Hagina, Jelena Storozenko, Liene Nikitina-Zake, Ludmila Viksn. Association of human leukocyte antigen class II alleles with epithelial cell apoptosis and extracellular matrix production in acute COVID-19. Central-European journal of immunology. vol 48. issue 4. 2024-04-01. PMID:38558559. |
association of human leukocyte antigen class ii alleles with epithelial cell apoptosis and extracellular matrix production in acute covid-19. |
2024-04-01 |
2024-04-04 |
human |
| Ieva Vanaga, Oksana Kolesova, Aleksandrs Kolesovs, Gunta Sture, Elvira Hagina, Jelena Storozenko, Liene Nikitina-Zake, Ludmila Viksn. Association of human leukocyte antigen class II alleles with epithelial cell apoptosis and extracellular matrix production in acute COVID-19. Central-European journal of immunology. vol 48. issue 4. 2024-04-01. PMID:38558559. |
our study assessed the relationships between hla class ii alleles and covid-19 severity and blood-based indicators of systemic inflammation and organ damage, serum markers of epithelial cell apoptosis such as caspase-cleaved ck18 fragment m30 (ck18-m30) and the extracellular matrix product hyaluronic acid (ha). |
2024-04-01 |
2024-04-04 |
human |
| Abedeh Rezaei, Amin Moqadami, Mohammad Khalaj-Kondori, Mohammad Ali Hosseinpour Feiz. Minocycline induced apoptosis and suppressed expression of matrix metalloproteinases 2 and 9 in the breast cancer MCF-7 cells. Molecular biology reports. vol 51. issue 1. 2024-03-29. PMID:38551800. |
minocycline induced apoptosis and suppressed expression of matrix metalloproteinases 2 and 9 in the breast cancer mcf-7 cells. |
2024-03-29 |
2024-04-01 |
Not clear |
| Chun-Yen Wu, Da-Fong Song, Zhi-Jia Chen, Chao-Sheng Hu, David Pei-Cheng Lin, Han-Hsin Chan. Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy. Biology. vol 13. issue 3. 2024-03-27. PMID:38534403. |
the mechanism analysis showed multi-fold abnormalities, including oxidative stress-induced cornea epithelium apoptosis and inflammation, extracellular matrix remodeling in the stroma, and a disruption of epithelial repair, presumably through the epithelial-mesenchymal transition. |
2024-03-27 |
2024-03-29 |
mouse |
| Ye Feng, Zhengzhe Li, Heather Wang, Bi-Cheng Liu, Kyung Lee, John Cijiang H. HIPK2 C-terminal domain inhibits NF-κB signaling and renal inflammation in kidney injury. JCI insight. 2024-03-21. PMID:38512421. |
it acts as a central effector of multiple signaling pathways implicated in kidney injury, such as tgf-β/smad3-mediated extracellular matrix accumulation, nf-κb-mediated inflammation, and p53-mediated apoptosis. |
2024-03-21 |
2024-03-24 |
mouse |
| Amin Moqadami, Mohammad Khalaj-Kondori, Mohammad Ali Hosseinpour Feizi, Behzad Baradara. Minocycline declines interleukin-1ß-induced apoptosis and matrix metalloproteinase expression in C28/I2 chondrocyte cells: an in vitro study on osteoarthritis. EXCLI journal. vol 23. 2024-03-15. PMID:38487083. |
minocycline declines interleukin-1ß-induced apoptosis and matrix metalloproteinase expression in c28/i2 chondrocyte cells: an in vitro study on osteoarthritis. |
2024-03-15 |
2024-03-17 |
human |
| Amin Moqadami, Mohammad Khalaj-Kondori, Mohammad Ali Hosseinpour Feizi, Behzad Baradara. Minocycline declines interleukin-1ß-induced apoptosis and matrix metalloproteinase expression in C28/I2 chondrocyte cells: an in vitro study on osteoarthritis. EXCLI journal. vol 23. 2024-03-15. PMID:38487083. |
interleukin-1 beta (il-1β) is increased in the injured joints and contributes to the oa pathobiology by inducing chondrocyte apoptosis and up-regulation of matrix metalloproteinases (mmps). |
2024-03-15 |
2024-03-17 |
human |
| Yaling Yu, Yixin Jiang, Hongfan Ge, Xiaoli Fan, Hang Gao, Zhenlei Zho. HIF-1α in cartilage homeostasis, apoptosis, and glycolysis in mice with steroid-induced osteonecrosis of the femoral head. Journal of cellular physiology. 2024-03-14. PMID:38481029. |
in this study, sonfh models were established using methylprednisolone (mps) in mouse and its proliferating chondrocytes to investigate the role of hif-1α in cartilage differentiation, extracellular matrix (ecm) homeostasis, apoptosis and glycolysis in sonfh mice. |
2024-03-14 |
2024-03-16 |
mouse |
| Shuai Li, Jinpeng Du, Yunfei Huang, Shenglong Gao, Zhigang Zhao, Zhen Chang, Xuefang Zhang, BaoRong H. From hyperglycemia to intervertebral disc damage: exploring diabetic-induced disc degeneration. Frontiers in immunology. vol 15. 2024-03-06. PMID:38444852. |
diabetes and advanced glycation end products (ages) accumulation- can lead to various adverse effects on the ivd, including cell senescence, apoptosis, pyroptosis, proliferation, and extracellular matrix (ecm) degradation. |
2024-03-06 |
2024-03-08 |
Not clear |
| Anwesha Mukherjee, Bodhisatwa Da. The role of inflammatory mediators and matrix metalloproteinases (MMPs) in the progression of osteoarthritis. Biomaterials and biosystems. vol 13. 2024-03-05. PMID:38440290. |
the critical role of inflammation in the pathogenesis of oa is discussed in detail along with the dysregulation within the cytokine networks composed of inflammatory and anti-inflammatory cytokines that drive catabolic pathways, inhibit matrix synthesis, and promote cellular apoptosis. |
2024-03-05 |
2024-03-07 |
Not clear |
| Ya-Ruo Lei, Xian-Lu He, Jun Li, Chun-Fen M. Drug Resistance in Hepatocellular Carcinoma: Theoretical Basis and Therapeutic Aspects. Frontiers in bioscience (Landmark edition). vol 29. issue 2. 2024-02-29. PMID:38420802. |
drug resistance exhibits multiple and complex molecular mechanisms to antagonize therapy under pharmacological pressure, including overexpression of drug efflux transporters, downstream adaptive response (such as apoptosis, autophagy, and endoplasmic reticulum stress), dysfunction of dna damage repair (ddr), epigenetic modification, tumor microenvironment (tme) as well as extracellular matrix (ecm). |
2024-02-29 |
2024-03-02 |
Not clear |
| Chao Song, Peixuan Hu, Renpeng Peng, Feng Li, Zhong Fang, Yong X. Bioenergetic dysfunction in the pathogenesis of intervertebral disc degeneration. Pharmacological research. 2024-02-28. PMID:38417775. |
hyperglycemia in diabetic diseases leads to cell senescence, the senescence-associated phenotype (sasp), apoptosis and catabolism of extracellualr matrix in ivds. |
2024-02-28 |
2024-03-02 |
human |
| Yan Zhang, Qiang Lyu, Xiao Han, Xu Wang, Ran Liu, Jing Hao, Li Zhang, Xiang-Mei Che. Proteomic analysis of multiple organ dysfunction induced by rhabdomyolysis. Journal of proteomics. 2024-02-25. PMID:38403185. |
serpina3n is a secreted protein and specifically inhibits a variety of proteases and participates in multiple physiological processes such as complement activation, inflammatory responses, apoptosis pathways, and extracellular matrix metabolism. |
2024-02-25 |
2024-02-28 |
rat |
| Nan Wang, Weihao Rong, Yimin Xie, Shuang Chen, Zhipeng Xi, Rongrong Den. Visualizing the bibliometrics of the inflammatory mechanisms in intervertebral disc degeneration. Experimental gerontology. 2024-02-21. PMID:38382680. |
the progression of ivdd is linked to structural and functional alterations in tissues, where an imbalance in the inflammatory microenvironment can induce extracellular matrix (ecm) degradation, senescence, and apoptosis. |
2024-02-21 |
2024-02-24 |
Not clear |
| Jie Chen, Bin Zhang, Liwei Wu, Jiabin X. Ginsenoside Rg3 exhibits anti-catabolic and anti-apoptotic effects in IL-1β treated human disc nucleus pulposus cells and in a rat model of disc degeneration by inactivating the MAPK pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 1. 2024-02-19. PMID:38372089. |
idd is characterized by a large number of apoptosis of nucleus pulposus cells (npcs) and extracellular matrix (ecm) degradation. |
2024-02-19 |
2024-02-21 |
human |