| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James Scott Miners, Shabnam Baig, Jennifer Palmer, Laura E Palmer, Patrick G Kehoe, Seth Lov. Abeta-degrading enzymes in Alzheimer's disease. Brain pathology (Zurich, Switzerland). vol 18. issue 2. 2008-07-10. PMID:18363935. |
other enzymes shown capable of degrading abetain vitro or in animal studies include plasmin; endothelin-converting enzymes ece-1 and -2; matrix metalloproteinases mmp-2, -3 and -9; and angiotensin-converting enzyme (ace). |
2008-07-10 |
2023-08-12 |
Not clear |
| Natalia N Nalivaeva, Lilia R Fisk, Nikolai D Belyaev, Anthony J Turne. Amyloid-degrading enzymes as therapeutic targets in Alzheimer's disease. Current Alzheimer research. vol 5. issue 2. 2008-05-15. PMID:18393806. |
these include, among others, neprilysin (nep) and its homologue endothelin-converting enzyme (ece), insulysin (ide), angiotensin-converting enzyme (ace) and matrix metalloproteinase-9 (mmp-9). |
2008-05-15 |
2023-08-12 |
Not clear |
| Xiaohua Xu, Wenhan Wan, Anthony S Powers, Ji Li, Lisa L Ji, Shunhua Lao, Bryan Wilson, John M Erikson, John Q Zhan. Effects of exercise training on cardiac function and myocardial remodeling in post myocardial infarction rats. Journal of molecular and cellular cardiology. vol 44. issue 1. 2008-03-06. PMID:17980387. |
we measured the changes in collagen volume fraction, matrix metalloproteinase (mmp) 1, tissue inhibitor matrix metalloproteinase 1 (timp-1), angiotensin ii receptor type 1 (at1), and angiotensin converting enzyme (ace) at gene and protein levels after 8 weeks of exercise training. |
2008-03-06 |
2023-08-12 |
rat |
| Daisuke Yamamoto, Shinji Takai, Denan Jin, Sachiko Inagaki, Kazuhiko Tanaka, Mizuo Miyazak. Molecular mechanism of imidapril for cardiovascular protection via inhibition of MMP-9. Journal of molecular and cellular cardiology. vol 43. issue 6. 2008-02-07. PMID:17884087. |
to investigate the inhibitory specificity of angiotensin converting enzyme (ace) inhibitors to matrix metalloproteinase (mmp)-9, we predicted molecular interactions between an ace inhibitor imidapril and mmp-9 active site based on recent x-ray structural analyses. |
2008-02-07 |
2023-08-12 |
Not clear |
| Sylvia Heeneman, Judith C Sluimer, Mat J A P Daeme. Angiotensin-converting enzyme and vascular remodeling. Circulation research. vol 101. issue 5. 2007-09-27. PMID:17761934. |
ace and ang ii are involved in the remodeling of large and resistance arteries during hypertension; here, cell proliferation and matrix remodeling are also regulated by signaling events downstream of the at(1) receptor. |
2007-09-27 |
2023-08-12 |
Not clear |
| Sylvia Heeneman, Judith C Sluimer, Mat J A P Daeme. Angiotensin-converting enzyme and vascular remodeling. Circulation research. vol 101. issue 5. 2007-09-27. PMID:17761934. |
here, a direct effect of ace inhibitors on matrix metalloproteinase activity has to be considered as part of the working mechanism. |
2007-09-27 |
2023-08-12 |
Not clear |
| Qing Liu, Karthe Ponnuraj, Yi Xu, Vannakambadi K Ganesh, Jouko Sillanpää, Barbara E Murray, Sthanam V L Narayana, Magnus Höö. The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model. The Journal of biological chemistry. vol 282. issue 27. 2007-09-17. PMID:17392280. |
we have determined the crystal structure of the ligand binding segment of the enterococcus faecalis collagen binding mscramm ace (microbial surface components recognizing adhesive matrix molecules adhesin of collagen from enterococci). |
2007-09-17 |
2023-08-12 |
Not clear |
| Gregory L Brower, Scott P Levick, Joseph S Janick. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. American journal of physiology. Heart and circulatory physiology. vol 292. issue 6. 2007-08-02. PMID:17308006. |
inhibition of matrix metalloproteinase activity by ace inhibitors prevents left ventricular remodeling in a rat model of heart failure. |
2007-08-02 |
2023-08-12 |
rat |
| Gregory L Brower, Scott P Levick, Joseph S Janick. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. American journal of physiology. Heart and circulatory physiology. vol 292. issue 6. 2007-08-02. PMID:17308006. |
the mechanism of action of ace inhibitors is still unclear, but evidence suggests that they may act by influencing matrix metalloproteinase (mmp) activity. |
2007-08-02 |
2023-08-12 |
rat |
| Hidekazu Tanaka, Shinji Takai, Denan Jin, Keiichi Furubayashi, Nao Inoue, Yoshinaga Kajimoto, Shin-Ichi Miyatake, Toshihiko Kuroiwa, Mizuo Miyazak. Inhibition of matrix metalloproteinase-9 activity by trandolapril after middle cerebral artery occlusion in rats. Hypertension research : official journal of the Japanese Society of Hypertension. vol 30. issue 5. 2007-07-18. PMID:17587759. |
we investigated whether an angiotensin-converting enzyme (ace) inhibitor could inhibit matrix metalloproteinase (mmp) activities in cerebral infarct lesions after middle cerebral artery occlusion (mcao) in rats. |
2007-07-18 |
2023-08-12 |
rat |
| I Kara, E Ozkok, M Aydin, N Orhan, Y Cetinkaya, M Gencer, G Kilic, H Tirel. Combined effects of ACE and MMP-3 polymorphisms on migraine development. Cephalalgia : an international journal of headache. vol 27. issue 3. 2007-05-31. PMID:17381556. |
since angiotensin-converting enzyme (ace) and matrix metalloproteinase (mmp) share the same homology, we investigated whether the mmp-3 and ace i/d gene variants are involved in migraine risk and whether the ace variant might act in combination with the mmp-3 genetic variant in patients with migraine. |
2007-05-31 |
2023-08-12 |
human |
| Daisuke Yamamoto, Shinji Takai, Mizuo Miyazak. Prediction of interaction mode between a typical ACE inhibitor and MMP-9 active site. Biochemical and biophysical research communications. vol 354. issue 4. 2007-04-17. PMID:17275782. |
to characterize the inhibitory specificity of angiotensin converting enzyme (ace) inhibitors for matrix metalloproteinase 9 (mmp-9) activity, molecular modeling of these complex was performed referring the recent x-ray structure analyses using lisinopril as an ace inhibitor. |
2007-04-17 |
2023-08-12 |
Not clear |
| Thomas D Ryan, Emily C Rothstein, Inmaculada Aban, Jose A Tallaj, Ahsan Husain, Pamela A Lucchesi, Louis J Dell'Itali. Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede cardiomyocyte elongation in rats with volume overload. Journal of the American College of Cardiology. vol 49. issue 7. 2007-03-12. PMID:17306712. |
we hypothesized that left ventricular (lv) remodeling and matrix loss in volume overload (vo) are mediated by bradykinin (bk) and exacerbated by chronic angiotensin-converting enzyme (ace) inhibition. |
2007-03-12 |
2023-08-12 |
rat |
| Oguzhan Deyneli, Dilek Yavuz, Ayliz Velioglu, Hasan Cacina, Nihal Aksoy, Goncagül Haklar, Yavuz Taga, Sema Akali. Effects of ACE inhibition and angiotensin II receptor blockade on glomerular basement membrane protein excretion and charge selectivity in type 2 diabetic patients. Journal of the renin-angiotensin-aldosterone system : JRAAS. vol 7. issue 2. 2007-01-11. PMID:17083064. |
the aim of this study was to compare the effects of an at1 blocker losartan and an ace inhibitor (ace-i) enalapril on uae, extracellular matrix proteins, glycosaminoglycan excretion (ugag) and red blood cell anionic charge (rbcch) which are the indirect markers of glomerular basement membrane anionic content in hypertensive type 2 diabetic patients. |
2007-01-11 |
2023-08-12 |
Not clear |
| Natan Cohen, Ahuva Goli. Zinc balance and medications commonly used in the management of heart failure. Heart failure reviews. vol 11. issue 1. 2006-11-21. PMID:16819574. |
matrix metalloproteinases (mmps) and ace are zinc-containing enzymes, which play a role in the process of remodeling in hf. |
2006-11-21 |
2023-08-12 |
Not clear |
| Shu-zhen Sun, Yi Wang, Qian Li, Yong-jie Tian, Ming-hua Liu, Yong-hui Y. Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats. Chinese medical journal. vol 119. issue 10. 2006-06-29. PMID:16732983. |
the present study was undertaken to investigate the activity of matrix metalloproteinase-2 (mmp-2), the expression of mmp-2 and tissue inhibitor of metalloproteinase-2 (timp-2) in kidney tissues of diabetic rats, and to explore the degradative pathway of type iv collagen (iv-c) and the renal protective effects of ace inhibition-benazepril. |
2006-06-29 |
2023-08-12 |
rat |
| Sarah E Medlan. Parameterization of sex-limited autosomal linkage analysis for Mx. Twin research and human genetics : the official journal of the International Society for Twin Studies. vol 8. issue 6. 2006-03-14. PMID:16354498. |
the present note provides a parameterization of the nonscalar sex-limitation ace model incorporating autosomal sex-limited qtl effects for use with the mx matrix algebra program (neale et al., 2002). |
2006-03-14 |
2023-08-12 |
Not clear |
| Eisuke Ishizaki, Shinji Takai, Mari Ueki, Takatoshi Maeno, Midori Maruichi, Tetsuya Sugiyama, Hidehiro Oku, Tsunehiko Ikeda, Mizuo Miyazak. Correlation between angiotensin-converting enzyme, vascular endothelial growth factor, and matrix metalloproteinase-9 in the vitreous of eyes with diabetic retinopathy. American journal of ophthalmology. vol 141. issue 1. 2006-01-31. PMID:16386986. |
to investigate the involvement of angiotensin-converting enzyme (ace) with angiogenic factors, vascular endothelial growth factor (vegf), and matrix metalloproteinase (mmp)-9 in the vitreous of eyes with proliferative diabetic retinopathy (pdr). |
2006-01-31 |
2023-08-12 |
Not clear |
| R N Williams, S L Parsons, T M Morris, B J Rowlands, S A Watso. Inhibition of matrix metalloproteinase activity and growth of gastric adenocarcinoma cells by an angiotensin converting enzyme inhibitor in in vitro and murine models. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. vol 31. issue 9. 2006-01-19. PMID:15993560. |
angiotensin converting enzyme (ace) shares structural homology with the matrix metalloproteinase family of proteolytic enzymes (mmps) responsible for degradation of the extracellular matrix (ecm). |
2006-01-19 |
2023-08-12 |
Not clear |
| Enzo Porteri, Luigi Rodella, Damiano Rizzoni, Rita Rezzani, Silvia Paiardi, Intissar Sleiman, Carolina De Ciuceis, Gianluca E M Boari, Maurizio Castellano, Rossella Bianchi, Enrico Agabiti-Rose. Effects of olmesartan and enalapril at low or high doses on cardiac, renal and vascular interstitial matrix in spontaneously hypertensive rats. Blood pressure. vol 14. issue 3. 2005-10-07. PMID:16036499. |
we have evaluated the effects of different doses of an angiotensin-converting enzyme (ace) inhibitor, enalapril (ena) and of an angiotensin ii type 1 receptor blocker olmesartan (olm), on extracellular matrix of the heart, kidney, aorta and mesenteric artery of spontaneously hypertensive rats (shr). |
2005-10-07 |
2023-08-12 |
rat |