| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rafaela de Assiz Louback, Karina Martins-Cardoso, Luzineide W Tinoco, Federica Collino, Ana Paula D N de Barros, Anneliese Fortuna-Costa, Robson Q Monteiro, Maria Isabel Doria Rossi, Rafael Soares Lindos. Aspirin Affects MDA-MB-231 Vesicle Production and Their Capacity to Induce Fibroblasts towards a Pro-Invasive State. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569393. |
fibroblasts stimulated with evs derived from mda-mb-231 treated with asa (ev-asa) showed a lower expression of alpha-smooth muscle actin (α-sma), matrix metalloproteinase-2 (mmp2) but not fibroblast activation protein (fap) in respect to the ones stimulated with evs from untreated breast cancer cells (ev-ctr). |
2023-08-12 |
2023-08-16 |
Not clear |
| Ziyu Zhang, Zepeng Li, Xiao Chen, Yinhua Wang, Xianwei L. Effect of AR gene-specific knockout on the process of radiation-induced pulmonary fibrosis and its mechanism. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 5. 2023-08-12. PMID:37571887. |
in vivo, ar deficiency significantly alleviated radiation-induced histopathological changes, reduced collagen deposition and inhibited collagen i, matrix metalloproteinase 2 (mmp2) and twist1 expression. |
2023-08-12 |
2023-08-16 |
mouse |
| Jung-Chien Cheng, Qingxue Meng, Qian Zhang, Lingling Zhang, Jiaye Chen, Tinglin Song, Lanlan Fang, Ying-Pu Su. WNK1 mediates amphiregulin-induced MMP9 expression and cell invasion in human extravillous trophoblast cells. Molecular and cellular endocrinology. 2023-08-06. PMID:37544354. |
areg upregulated matrix metalloproteinase 9 (mmp9) but not mmp2. |
2023-08-06 |
2023-08-14 |
human |
| SarahBeth D Votra, Deema Alsalih, Dimitra Bourbouli. Methods to Assess the Impact of Hsp90 Chaperone Function on Extracellular Client MMP2 Activity. Methods in molecular biology (Clifton, N.J.). vol 2693. 2023-08-04. PMID:37540438. |
demonstrated that ehsp90 promotes the invasion of breast cancer cells by binding to and regulating the activity of an extracellular matrix (ecm) remodeling enzyme, the matrix metalloproteinase 2 or mmp2. |
2023-08-04 |
2023-08-14 |
human |
| Xiaoyu Zou, He Zhang, Jamie M Benson, Hanyuan Gao, David L Burris, Joseph M Fox, Xinqiao Ji. Modeling the Maturation of the Vocal Fold Lamina Propria Using a Bioorthogonally Tunable Hydrogel Platform. Advanced healthcare materials. 2023-08-02. PMID:37530909. |
compared to the nlp controls, slp7 conditions upregulated the expression of fibrous matrix proteins (col i, dcn, and fn eda), classic fibroblastic markers (tnc, fap, and fsp1), and matrix remodeling enzymes (mmp2, timp1, and has3). |
2023-08-02 |
2023-08-14 |
Not clear |
| Xinglu Zhou, Changmei Zhang, Qiquan Zhou, Jian Liang, Xiaoyan Zhang, Yujie Shi, Jingna Zhu, Lei Zhon. Imaging application of an MMP2-sensitive tumor-targeted prussian blue fluorescent nanoprobe. Journal of biomaterials applications. 2023-08-02. PMID:37531192. |
our research group has synthesized a kind of nanocarrier, mpeg2000-gplgiagq-dspe, which has the characteristic of matrix metalloproteinase-2 (mmp2) sensitive ability in tumor microenvironment. |
2023-08-02 |
2023-08-14 |
Not clear |
| Wenyan Xu, Lingran Du, Lina Yu, Huiyu Cen, Fangyu Lin, Siran Wang, Zhixiong Ruan, Zhongxiao Lin, Xin Zhang, Na Zhou, Jishuo Chang, Xiyong Yu, Lingmin Zhang, Lu Lian. The mirrored cationic peptide as miRNA vehicle for efficient lung cancer therapy. MedComm. vol 4. issue 4. 2023-07-31. PMID:37521428. |
furthermore, rd24 showed matrix metallopeptidase 2 (mmp2) responsiveness, which improved lung cancer cell inhibition induced by the mirna intracellularly. |
2023-07-31 |
2023-08-14 |
Not clear |
| Ming Yang, Jun Luo, Shuhua Zhang, Qing Huang, Qianqiang Ca. Knockdown of circ_0113656 assuages oxidized low-density lipoprotein-induced vascular smooth muscle cell injury through the miR-188-3p/IGF2 pathway. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-07. PMID:37415611. |
the protein expression of proliferating cell nuclear antigen (pcna), matrix metalloprotein 2 (mmp2), and igf2 was detected by western blotting. |
2023-07-07 |
2023-08-14 |
Not clear |
| Hugo Sato, María Laura Leonardi, Sabrina Lorena Roberti, Alicia Jawerbaum, Romina Hig. Maternal diabetes increases FOXO1 activation during embryonic cardiac development. Molecular and cellular endocrinology. 2023-06-30. PMID:37391062. |
these alterations were related to increases in the levels of 4-hydroxynonenal (an oxidative stress marker) and increased mrna levels of inducible nitric oxide synthase, angiopoietin-2 and matrix metalloproteinase-2 (mmp2) (all foxo1 target genes relevant for cardiac development). |
2023-06-30 |
2023-08-14 |
rat |
| Giovanna Casili, Sarah Adriana Scuderi, Marika Lanza, Alessia Filippone, Deborah Mannino, Raffaella Giuffrida, Cristina Colarossi, Marzia Mare, Anna Paola Capra, Federica De Gaetano, Marco Portelli, Angela Militi, Salvatore Cuzzocrea, Irene Paterniti, Emanuela Esposit. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC). Cancers. vol 15. issue 10. 2023-06-22. PMID:37345134. |
additionally, bay-117082 treatment modulated the epithelial-mesenchymal transition (emt) process in tongue tissue as well as in metastatic organs such as lymph node, lung, and spleen, also reducing the expression of matrix metalloproteinases (mmps), particularly mmp2 and mmp9, markers of cell invasion and migration. |
2023-06-22 |
2023-08-14 |
human |
| Soojung Hahn, Bae Jun Oh, Hyemin Kim, In Woong Han, Sang Hyun Shin, Gyuri Kim, Sang-Man Jin, Jae Hyeon Ki. Anti-cancer effects of metformin in a 3D co-culture model of pancreatic ductal adenocarcinoma. American journal of cancer research. vol 13. issue 5. 2023-06-09. PMID:37293149. |
at a concentration of 10 μm, metformin reduced the migratory ability of the pscs by downregulating the expression of matrix metalloproteinase-2 (mmp2). |
2023-06-09 |
2023-08-14 |
mouse |
| Rebecca Oramas, Elizabeth Knapp, Baosheng Zeng, Jianjun Su. The bHLH-PAS transcriptional complex Sim:Tgo plays active roles in late oogenesis to promote follicle maturation and ovulation. Development (Cambridge, England). 2023-05-23. PMID:37218521. |
in addition, we discovered that re-upregulation of sim in stage-14 follicle cells is also essential to promote ovulatory competency by upregulating octopamine receptor in mushroom body (oamb), matrix metalloproteinase 2 (mmp2), and nadph oxidase (nox), either independent of or in conjunction with the zinc-finger protein hindsight (hnt). |
2023-05-23 |
2023-08-14 |
drosophila_melanogaster |
| Huixian Zheng, Chaoyi Hu, Yunyun Quan, Xiaoxia Ye, Xiangchao Shi, Zijian Guo, Xiaoyong Wan. A copper complex that combats triple negative breast cancer by restraining angiogenesis. Dalton transactions (Cambridge, England : 2003). 2023-05-17. PMID:37195167. |
moreover, cpt8 suppressed the expression of vascular endothelial cadherin and matrix metalloproteinases mmp2 and mmp9, leading to the inhibition of vasculogenic mimicry formation. |
2023-05-17 |
2023-08-14 |
human |
| Noureldien H E Darwish, Khaled A Hussein, Khaled Elmasry, Ahmed S Ibrahim, Julia Humble, Mohamed Moustafa, Fatma Awadalla, Mohamed Al-Shabrawe. Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy. Cells. vol 12. issue 9. 2023-05-14. PMID:37174679. |
the impact of bmp4 on matrix metalloproteinases (mmp2 and mmp9) was also evaluated using specific elisa kits. |
2023-05-14 |
2023-08-14 |
mouse |
| Jiaye Chen, Tinglin Song, Sizhu Yang, Qingxue Meng, Xiaoyu Han, Ze Wu, Jung-Chien Cheng, Lanlan Fan. Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression. Cell communication and signaling : CCS. vol 21. issue 1. 2023-05-04. PMID:37143106. |
growth differentiation factor-8 (gdf-8), a member of the transforming growth factor-beta (tgf-β) superfamily, is expressed in the human placenta and promotes evt cell invasion by upregulating the expression of matrix metalloproteinase 2 (mmp2). |
2023-05-04 |
2023-08-14 |
human |
| Suhaas R Mandala, Alexis J Thomson, Etienne C Gozlan, Dhruv N Patel, Andrea Chobrutskiy, Boris I Chobrutskiy, George Blanc. A Bioinformatics Assessment Indicating Better Outcomes With Breast Cancer Resident, Immunoglobulin CDR3-MMP2 Binding. Cancer genomics & proteomics. vol 20. issue 3. 2023-04-24. PMID:37093687. |
thus, cancer patients may have varying degrees of cdr3 aa binding specificity for cancer proteases, for example, matrix metalloproteinase 2 (mmp2). |
2023-04-24 |
2023-08-14 |
Not clear |
| Alaleh Mohammadi, Souzan Najafi, Mohammad Amini, Behzad Baradaran, Masoumeh Firouzamand. B7H6 silencing increases chemosensitivity to dacarbazine and suppresses cell survival and migration in cutaneous melanoma. Melanoma research. 2023-04-13. PMID:37053079. |
b7h6 suppression combined with dacarbazine restrained cell migration through suppression of matrix metalloproteinase (mmp) expression, including mmp2, mmp3, and mmp9. |
2023-04-13 |
2023-08-14 |
Not clear |
| Marjan Shakiba, Fariba Alae. A novel gene mutation for multicentric osteolysis nodulosis and arthropathy: Case report and review of literature. Heliyon. vol 9. issue 4. 2023-04-07. PMID:37025869. |
mutation in matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 14 (mmp14) and sh3pxd2b are known genetic defects in these disorders. |
2023-04-07 |
2023-08-14 |
Not clear |
| Yuye Wang, Luying Qiu, Shumin Deng, Fang Liu, Zhiyi He, Mengye Li, Yanzhe Wan. Ursolic Acid Promotes Microglial Polarization Toward the M2 Phenotype Via PPARγ Regulation of MMP2 Transcription. Neurotoxicology. 2023-04-05. PMID:37019307. |
additionally, ua increases tissue inhibitor matrix metalloproteinase 1 (timp1), while greatly reducing the release of matrix metalloproteinase 2 (mmp2) and mmp9 in a pparγ-dependent manner. |
2023-04-05 |
2023-08-14 |
rat |
| Silvija Mašić, Jasna Bacalja, Majda Vučić, Hrvoje Čupić, Davor Tomas, Monika Ulamec, Borislav Spajić, Faruk Skenderi, Božo Krušli. CORRELATION OF EXPRESSION OF TGF- β AND MMP2 BETWEEN PROSTATIC ADENOCARCINOMA AND ADJACENT UNAFFECTED PARENCHYMA. Acta clinica Croatica. vol 61. issue Suppl 3. 2023-03-20. PMID:36938549. |
matrix metalloproteinase 2 (mmp2), the endopeptidase that degrades extracellular matrix is considered to be overexpressed in prostatic carcinoma related to its growth and aggressiveness. |
2023-03-20 |
2023-08-14 |
Not clear |