| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Halasa, Ahmed Uosef, Henry V Ubelaker, Arijita Subuddhi, Krupa R Mysore, Jacek Z Kubiak, Rafik M Ghobrial, Jarek Wosik, Malgorzata Klo. Gadolinium retention effect on macrophages - a potential cause of MRI contrast agent Dotarem toxicity. Cell and tissue research. 2024-04-16. PMID:38625373. |
gadolinium retention for 7 days decreased macrophage adhesion and motility and dysregulated the expression of adhesion and fibrotic pathway-related proteins such as notch1 and its ligand jagged1, adhesion/migration-related proteins pak1 and shp1, immune response-related transcription factors smad3 and tcf19, and chemokines cxcl10 and cxcl13, and dysregulated the mrna expression of fibrosis-related genes involved in extracellular matrix (ecm) synthesis, such as col6a1, fibronectin, mmp9, and mmp12. |
2024-04-16 |
2024-04-18 |
Not clear |
| Yulong Zhang, Chenxi Gao, Juncong Luo, Arsalan Khan, Mounir M Salem-Bekhit, Mohamed M Salem, Zeng Qi, Bo Jian. Deciphering the role of wound healing genes in skin cutaneous melanoma: Insights into expression, methylation, mutations, and therapeutic implications. International wound journal. vol 21. issue 4. 2024-04-09. PMID:38591163. |
in this comprehensive study, we investigated the intricate roles of two important wound healing genes in skcm, including matrix metalloproteinase-2 (mmp2) and matrix metalloproteinase-9 (mmp9). |
2024-04-09 |
2024-04-11 |
Not clear |
| Huirong Li, Liang Ding, Jian Ding, Fudan Huan. The Influence of CD40/CD40L, MMP2/MMP9 on Uterine Artery Blood Flow and Their Expression in Recurrent Miscarriage. Alternative therapies in health and medicine. 2024-04-06. PMID:38581334. |
this study aims to investigate the expression levels of soluble cd40l (scd40l), matrix metalloproteinase 2 (mmp2), and matrix metalloproteinase 9 (mmp9) in the serum of patients experiencing recurrent abortion and their impact on uterine artery blood flow. |
2024-04-06 |
2024-04-10 |
Not clear |
| Kunlun Li, Dandan Li, Barbod Hafez, Mounir M Salem Bekhit, Yousef A Bin Jardan, Fars Kaed Alanazi, Ehab I Taha, Sayed H Auda, Faiqah Ramzan, Muhammad Jami. Identifying and validating MMP family members (MMP2, MMP9, MMP12, and MMP16) as therapeutic targets and biomarkers in kidney renal clear cell carcinoma (KIRC). Oncology research. vol 32. issue 4. 2024-04-01. PMID:38560573. |
by performing string and cytohubba analyses of the 24 mmp gene family members, mmp2 (matrix metallopeptidase 2), mmp9 (matrix metallopeptidase 9), mmp12 (matrix metallopeptidase 12), and mmp16 (matrix metallopeptidase 16) genes were denoted as hub genes having highest degree scores. |
2024-04-01 |
2024-04-04 |
Not clear |
| Wen Guo, Mangmang Xu, Xindi Song, Yajun Cheng, Yilun Deng, Ming Li. Association of Serum Macrophage Migration Inhibitory Factor with 3-Month Poor Outcome and Malignant Cerebral Edema in Patients with Large Hemispheric Infarction. Neurocritical care. 2024-04-01. PMID:38561586. |
we aimed to investigate the associations of macrophage migration inhibitory factor (mif), toll-like receptors 2 and 4 (tlr2/4), and matrix metalloproteinase 9 (mmp9) with 3-month poor outcome, death, and malignant cerebral edema (mce) in patients with large hemispheric infarction (lhi). |
2024-04-01 |
2024-04-04 |
Not clear |
| Linping Wang, Luyi Chen, Daniel Schlenk, Feixue Li, Jing Li. Parabens promotes invasive properties of multiple human cells: A potential cancer-associated adverse outcome pathway. The Science of the total environment. 2024-03-28. PMID:38547973. |
mp and pp up-regulated the expression levels and enzymatic activities of matrix metalloproteinase 2 and 9 (mmp2 and mmp9), as well as altered the expression of the tissue inhibitors of metalloproteinase 1 and 2 (timp1 and timp2) in four cell lines, suggesting mmps/timps as potential key events (kes) for paraben-induced cell invasion. |
2024-03-28 |
2024-03-31 |
human |
| Yan Yang, Yue Cheng, Yanfei Mu, Xianjun Tang, Xiaosong M. Lentinan inhibits cell invasion via M2 polarization of tumor-associated macrophages and Wnt/β-catenin signaling in non-small cell lung cancer. Chemical biology & drug design. vol 103. issue 3. 2024-03-27. PMID:38538070. |
matrix metallopeptidase 9 (mmp9) levels were measured through immunofluorescence staining. |
2024-03-27 |
2024-03-30 |
Not clear |
| Bogdan Stelian Mastalier Manolescu, Angela Mădălina Lazar, George Sorin Ţiplica, Sabina Andrada Zurac, Adrian Reboşapcă, Bogdan Andreescu, Cristiana Gabriela Pop. MMP1, MMP9, MMP11 and MMP13 in melanoma and its metastasis - key points in understanding the mechanisms and celerity of tumor dissemination. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 65. issue 1. 2024-03-26. PMID:38527983. |
matrix metalloproteinase (mmp)1, mmp9, mmp11, and mmp13 are overexpressed in malignant melanoma (mm), being associated with tumor invasive phase, metastases, and more aggressive neoplastic phenotypes. |
2024-03-26 |
2024-03-28 |
Not clear |
| Haotian Zheng, Linxin Yang, Huashang Huang, Yazhou Lin, Lin Che. Morroniside improves AngII-induced cardiac fibroblast proliferation, migration, and extracellular matrix deposition by blocking p38/JNK signaling pathway through the downregulation of KLF5. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-13. PMID:38472369. |
in this study, it was found that mor treatment inhibited angii-induced hyperproliferation, migration, and fibrosis of hcf cells, accompanied with decreased activities of matrix metalloproteinase 2 (mmp2), matrix metalloproteinase 9 (mmp9), connective tissue growth factor (ctgf), fibronectin, and α-sma, which were all reversed by klf5 overexpression. |
2024-03-13 |
2024-03-15 |
human |
| Anthony Altieri, Courtney Lynn Marshall, Padmanie Ramotar, Dylan Lloyd, Mahadevappa Hemshekhar, Victor Spicer, Anne M van der Does, Neeloffer Mookherje. Human host defence peptide LL-37 suppresses TNFα-mediated matrix metalloproteinases MMP9 and MMP13, in human bronchial epithelial cells. Journal of innate immunity. 2024-03-12. PMID:38471488. |
human host defence peptide ll-37 suppresses tnfα-mediated matrix metalloproteinases mmp9 and mmp13, in human bronchial epithelial cells. |
2024-03-12 |
2024-03-15 |
human |
| Daniel Jussen, Syamend Saeed, Tatjana Jablonski, Harald Krenzlin, Kristin Lucia, Tobias Kraemer, Oliver Kempski, Marcus Czabanka, Florian Ringel, Beat Alessandr. Influence of Blood Components on Neuroinflammation, Blood-Brain Barrier Breakdown, and Functional Damage After Acute Subdural Hematoma in Rats. Neurotrauma reports. vol 5. issue 1. 2024-03-11. PMID:38463418. |
integrity of the bbb was evaluated with albumin and matrix metalloproteinase 9 (mmp9) staining. |
2024-03-11 |
2024-03-14 |
rat |
| Xiaolin Chen, Ningyuan Wang, Chenyang Jing, Jianghan Li, Xuanhao Liu, Yuquan Yang, Tianhuan Song, Hao Ji. The TGF-β/MMP9/RAGE axis induces sRAGE secretion by neutrophils and promotes oral carcinogenesis. Biochemistry and biophysics reports. vol 38. 2024-03-11. PMID:38463640. |
tgf-β was found to induce the expression of rage and matrix metalloproteinase 9 (mmp9) in neutrophils. |
2024-03-11 |
2024-03-14 |
mouse |
| Suvendu Nandi, Soumyadeep Bhaduri, Debraj Das, Priya Ghosh, Mahitosh Mandal, Pralay Mitr. Deciphering the Lexicon of Protein Targets: A Review on Multifaceted Drug Discovery in the Era of Artificial Intelligence. Molecular pharmaceutics. 2024-03-11. PMID:38466810. |
we have also demonstrated the pathological conditions of heat shock protein 27 (hsp27) and matrix metallopoproteinases (mmp2 and mmp9) and designed inhibitors of these proteins using the drug discovery paradigm in a case study on the discovery of drug molecules for cancer treatment. |
2024-03-11 |
2024-03-14 |
Not clear |
| Ajwan Z Albalawi, Areej S Alatawi, Shekha M Al-Atwi, Lama S Alhwyty, Kadi M Alharbi, Shahad A Alshehri, Wasayf A Almarwani, Khulud K Aljohani, Hanan M Hassan, Mohammed M H Al-Gayya. Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma. Biomolecules & biomedicine. 2024-03-10. PMID:38461536. |
the hepatic expression of mrna and protein levels of tgf-β1, β-catenin, smad4, matrix metalloproteinase-9 (mmp9), phosphoinositide 3-kinases (pi3k), mammalian target of rapamycin (mtor), connective tissue growth factor 2 (ccn2), e-cadherin, platelets derived growth factor (pdgf)-b and fascin were also analyzed. |
2024-03-10 |
2024-03-14 |
rat |
| Sepehr Zamani, Majid Salehi, Arian Ehterami, Mh Busra Fauzi, Ghasem Abbaszadeh-Goudarz. Assessing the efficacy of curcumin-loaded alginate hydrogel on skin wound healing: A gene expression analysis. Journal of biomaterials applications. 2024-03-07. PMID:38453252. |
furthermore, the treated group exhibited down-regulation of mmp9 gene expression, indicating a reduction in matrix degradation and inflammation. |
2024-03-07 |
2024-03-10 |
Not clear |
| Jiali Li, Yan Wu, Qi Yuan, Luxin Li, Wenqi Qin, Jia Jia, Kaiyuan Chen, Dan Wu, Xiaohuan Yua. Gelatin Microspheres Based on H8-Loaded Macrophage Membrane Vesicles to Promote Wound Healing in Diabetic Mice. ACS biomaterials science & engineering. 2024-03-07. PMID:38450619. |
the high expression of matrix metalloproteinase 9 (mmp9) and a high inflammatory response are indicative of poor diabetic wound healing. |
2024-03-07 |
2024-03-09 |
mouse |
| Kalyani Vemuri, Beatriz de Alves Pereira, Patricia Fuenzalida, Yelin Subashi, Stefano Barbera, Luuk van Hooren, Marie Hedlund, Fredrik Pontén, Cecilia Lindskog, Anna-Karin Olsson, Roberta Lugano, Anna Dimber. CD93 maintains endothelial barrier function and limits metastatic dissemination. JCI insight. 2024-03-05. PMID:38441970. |
primary melanoma growth was hampered in cd93-/- mice but metastatic dissemination was increased, associated with a disruption of adherens and tight junctions in tumor endothelial cells and elevated expression of matrix metalloprotease 9 (mmp9) at the metastatic site. |
2024-03-05 |
2024-03-08 |
mouse |
| Wei Fan, Hongping Chen, Meng Li, Xuehui Fan, Fangchao Jiang, Chen Xu, Yingju Wang, Wan Wei, Jihe Song, Di Zhong, Guozhong L. NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation. Scientific reports. vol 14. issue 1. 2024-03-04. PMID:38438409. |
similarly, sulforaphane (sfn) prevented the down-regulated tight junction proteins occludin and zonula occludens 1 (zo-1) and reduced the up-regulated aquaporin 4 (aqp4) and matrix metalloproteinase 9 (mmp9) after tmcao. |
2024-03-04 |
2024-03-07 |
mouse |
| Zhenhua Wang, Yuan Li, Zhixu Wang, Yuhui Liao, Qingqing Ye, Shilong Tang, Ting Wei, Pengyu Xiao, Juan Huang, Weitian L. Edaravone Maintains AQP4 Polarity Via OS/MMP9/β-DG Pathway in an Experimental Intracerebral Hemorrhage Mouse Model. Molecular neurobiology. 2024-02-29. PMID:38421470. |
edaravone or the specific inhibitor of matrix metalloproteinase 9 (mmp9), mmp9-in-1, called mmp9-inh was administered 10 min after ich via intraperitoneal injection. |
2024-02-29 |
2024-03-02 |
mouse |
| Samia Mahmoud Manawy, Eman Mohamed Faruk, Rabab Fawzy Hindawy, Mahmoud M Hassan, Diaa M G Farrag, Mansour A E Bashar, Hanan Fouad, Rania Abubaker Bagabir, Dina Allam Abdelmaksoud Hassan, Ahmed Mohammed Zaazaa, Mohamed Ghazy Attia Hablas, K Mostafa Kama. Modulation of the Sirtuin-1 signaling pathway in doxorubicin-induced nephrotoxicity (synergistic amelioration by resveratrol and pirfenidone). Tissue & cell. vol 87. 2024-02-27. PMID:38412579. |
renal tissue was collected to assess matrix metalloproteinase-9 (mmp9), inflammatory and apoptotic markers: tumor necrosis factor-alpha (tnf- β, caspase-3, cyclo-oxygenase-2 (cox-2), and oxidative stress markers: nitric oxide (no), glutathione (gsh), malondialdehyde (mda), and superoxide dismutase (sod). |
2024-02-27 |
2024-03-01 |
rat |