| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beatriz Martín-Fernández, Natalia de las Heras, María Miana, Sandra Ballesteros, Carmen Delgado, Su Song, Thomas Hintze, Victoria Cachofeiro, Vicente Laher. Structural, functional, and molecular alterations produced by aldosterone plus salt in rat heart: association with enhanced serum and glucocorticoid-regulated kinase-1 expression. Journal of cardiovascular pharmacology. vol 57. issue 1. 2011-06-01. PMID:20980916. |
relative heart weight, collagen content, messenger rna expression of transforming growth factor beta, connective tissue growth factor, matrix metalloproteinase 2, tissue inhibitor of metalloproteinases 2, tumor necrosis factor alpha, interleukin-1[beta], p22phox, endothelial nitric oxide synhtase, and sgk-1 were increased (p < 0.05) in aldosterone + salt-treated rats, being reduced by spironolactone (p < 0.05). |
2011-06-01 |
2023-08-12 |
rat |
| L Kular, J Pakradouni, P Kitabgi, M Laurent, C Martineri. The CCN family: a new class of inflammation modulators? Biochimie. vol 93. issue 3. 2011-05-26. PMID:21130134. |
in vitro, ccn expression is finely regulated by diverse inflammatory mediators including cytokines (tnfα, il1β, tgf-β), small factors such as prostaglandins, nitric oxide, histamine and serotonin, and extracellular matrix enzymes. |
2011-05-26 |
2023-08-12 |
Not clear |
| Yuanming Luo, Tao Xiao, Jinxi Hu, Wei Zeng, Hejia Hu, Xiangcheng Yan. [Effect of leptin on inducible NO and MMP-13 in rabbit articular chondrocytes in vitro]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 34. issue 10. 2011-05-02. PMID:19893248. |
to observe the in vitro effect of leptin, alone or in combination with tumor necrosis factor-alpha (tnf-alpha) on inducible nitric oxide(no)and on inducible matrix metalloproteinase-13 (mmp-13) in rabbit articular chondrocytes. |
2011-05-02 |
2023-08-12 |
rabbit |
| C Munjal, S Givvimani, N Qipshidze, N Tyagi, J C Falcone, S C Tyag. Mesenteric vascular remodeling in hyperhomocysteinemia. Molecular and cellular biochemistry. vol 348. issue 1-2. 2011-04-18. PMID:21076854. |
most of the vascular matrix metalloproteinase (mmp) are latent because of the presence of constitutive nitric oxide (no). |
2011-04-18 |
2023-08-12 |
mouse |
| Jérémie Sellam, Francis Berenbau. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nature reviews. Rheumatology. vol 6. issue 11. 2011-03-31. PMID:20924410. |
catabolic and proinflammatory mediators such as cytokines, nitric oxide, prostaglandin e(2) and neuropeptides are produced by the inflamed synovium and alter the balance of cartilage matrix degradation and repair, leading to excess production of the proteolytic enzymes responsible for cartilage breakdown. |
2011-03-31 |
2023-08-12 |
Not clear |
| Amanda S Harper-Leatherman, Jean Marie Wallace, Debra R Roliso. Cytochrome C stabilization and immobilization in aerogels. Methods in molecular biology (Clifton, N.J.). vol 679. 2011-01-24. PMID:20865398. |
c superstructures exhibit rapid gas-phase recognition of nitric oxide (no) within the aerogel matrix, as facilitated by the high-quality pore structure of the aerogel, and remain viable for weeks at room temperature. |
2011-01-24 |
2023-08-12 |
Not clear |
| Chi-Chien Niu, Li-Jen Yuan, Lih-Huei Chen, Song-Shu Lin, Tsung-Ting Tsai, Jen-Chung Liao, Po-Liang Lai, Wen-Jer Che. Beneficial effects of hyperbaric oxygen on human degenerated intervertebral disk cells via suppression of IL-1β and p38 MAPK signal. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 29. issue 1. 2011-01-11. PMID:20661932. |
nucleus pulposus cells (npcs) from degenerating disks produce catabolic and inflammatory factors, including interleukin (il)-1, nitric oxide (no), prostaglandin e2 (pge-2), and matrix metalloproteinaes (mmps). |
2011-01-11 |
2023-08-12 |
human |
| Chaoyong He, Hyoung Chul Choi, Zhonglin Xi. Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients. The American journal of pathology. vol 176. issue 5. 2010-12-15. PMID:20348234. |
pgis nitration, nitric oxide synthases, adhesion molecules, myeloperoxidase, osteopontin, and matrix metalloproteinase (mmp) were measured by using immunohistochemistry and western blotting. |
2010-12-15 |
2023-08-12 |
human |
| Teo Vargas, Cristina Ugalde, Carlos Spuch, Desiree Antequera, María J Morán, Miguel A Martín, Isidro Ferrer, Felix Bermejo-Pareja, Eva Carr. Abeta accumulation in choroid plexus is associated with mitochondrial-induced apoptosis. Neurobiology of aging. vol 31. issue 9. 2010-11-30. PMID:18838197. |
we propose a sequence of pathological steps that link abeta accumulation in cp epithelium with an enhanced nitric oxide production, mitochondrial dysfunction, and up-regulation of matrix metalloproteinase-9, which ultimately lead to cell death, and probably to csf barrier dysfunction. |
2010-11-30 |
2023-08-12 |
Not clear |
| Cathy Grutzmacher, SunYoung Park, Tammy L Elmergreen, Yixin Tang, Elizabeth A Scheef, Nader Sheibani, Christine M Sorenso. Opposing effects of bim and bcl-2 on lung endothelial cell migration. American journal of physiology. Lung cellular and molecular physiology. vol 299. issue 5. 2010-11-22. PMID:20656893. |
we also observed aberrant production of extracellular matrix proteins, enos expression, and nitric oxide production in bcl-2-/- lung ec, which could contribute to inability to undergo capillary morphogenesis. |
2010-11-22 |
2023-08-12 |
Not clear |
| Tamás Csont, Anikó Görbe, Erika Bereczki, Andrea Szunyog, Eda Aypar, Melinda E Tóth, Zoltán V Varga, Csaba Csonka, Ferenc Fülöp, Miklós Sántha, Péter Ferdinand. Biglycan protects cardiomyocytes against hypoxia/reoxygenation injury: role of nitric oxide. Journal of molecular and cellular cardiology. vol 48. issue 4. 2010-11-16. PMID:20096286. |
biglycan, a proteoglycan component of extracellular matrix, has been suspected to contribute to the development of atherosclerosis, but overexpression of biglycan in transgenic mice has been shown to induce cardioprotective genes including nitric oxide (no) synthases in the heart. |
2010-11-16 |
2023-08-12 |
mouse |
| Hyun Joo Jung, Mei Zi Yang, Ki Hyo Kwon, Midori A Yenari, Yoon Jung Choi, Won Taek Lee, Kyung Ah Park, Jong Eun Le. Endogenous agmatine inhibits cerebral vascular matrix metalloproteinases expression by regulating activating transcription factor 3 and endothelial nitric oxide synthesis. Current neurovascular research. vol 7. issue 3. 2010-11-12. PMID:20560878. |
endogenous agmatine inhibits cerebral vascular matrix metalloproteinases expression by regulating activating transcription factor 3 and endothelial nitric oxide synthesis. |
2010-11-12 |
2023-08-12 |
human |
| Heehong Hwang, Shinrye Lee, Won-Ha Lee, Ho-Jae Lee, Kyoungho Su. Stimulation of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) induces inflammatory activation of microglia in culture. Journal of neuroscience research. vol 88. issue 10. 2010-10-26. PMID:20162721. |
using bv-2 mouse microglia cells and mouse primary microglia cultures, we have demonstrated that 1) both gitr and gitrl are expressed in microglia cells; 2) stimulation of gitrl induces inflammatory activation of microglia on the basis of production of nitric oxide (no) and expression of inducible nitric oxide synthase, cyclooxygenase-2, cd40, and matrix metalloproteinase-9; 3) gitrl-mediated microglial no production partially depends on p38 mapk, jnk, and nuclear factor-kappab pathways; and 4) gitrl stimulation also induces microglia cell death. |
2010-10-26 |
2023-08-12 |
mouse |
| Mesia M Steed, Neetu Tyagi, Utpal Sen, Dale A Schuschke, Irving G Joshua, Suresh C Tyag. Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS-/-, and iNOS-/- mice. American journal of physiology. Lung cellular and molecular physiology. vol 299. issue 3. 2010-09-20. PMID:20581102. |
nitric oxide (no) is a potential regulator of matrix metalloproteinase (mmp) activity in mmp-no-tissue inhibitor of metalloproteinase (timp) inhibitory tertiary complex. |
2010-09-20 |
2023-08-12 |
mouse |
| Maria José da Silva, Ana Paula S Paim, Maria Fernanda Pimentel, M Luisa Cervera, Miguel de la Guardi. Determination of mercury in rice by cold vapor atomic fluorescence spectrometry after microwave-assisted digestion. Analytica chimica acta. vol 667. issue 1-2. 2010-08-02. PMID:20441864. |
the matrix interferences and the effect of nitrogen oxide vapors have been evaluated and the method validated using a certified reference material. |
2010-08-02 |
2023-08-12 |
Not clear |
| Saurabh S Dhawan, Ravi P Avati Nanjundappa, Jonathan R Branch, W Robert Taylor, Arshed A Quyyumi, Hanjoong Jo, Michael C McDaniel, Jin Suo, Don Giddens, Habib Samad. Shear stress and plaque development. Expert review of cardiovascular therapy. vol 8. issue 4. 2010-07-29. PMID:20397828. |
wall shear stress is a frictional force exerted parallel to the vessel wall that leads to alteration of the endothelial phenotype, endothelial cell signaling, gene and protein expression leading to a proinflammatory phenotype, reduced nitric oxide availability and disruption of the extracellular matrix, which in turn leads to plaque development. |
2010-07-29 |
2023-08-12 |
Not clear |
| Janet Y Uriu-Adams, Rachel E Scherr, Louise Lanoue, Carl L Kee. Influence of copper on early development: prenatal and postnatal considerations. BioFactors (Oxford, England). vol 36. issue 2. 2010-06-28. PMID:20232410. |
a number of mechanisms can contribute to the teratogenicity of cu including decreased activity of select cuproenzymes, increased oxidative stress, decreased nitric oxide availability, altered iron metabolism, abnormal extracellular matrix protein crosslinking, decreased angiogenesis and altered cell signaling among others. |
2010-06-28 |
2023-08-12 |
Not clear |
| Alexandra Schubert-Unkmeir, Christian Konrad, Heiko Slanina, Florian Czapek, Sabrina Hebling, Matthias Frosc. Neisseria meningitidis induces brain microvascular endothelial cell detachment from the matrix and cleavage of occludin: a role for MMP-8. PLoS pathogens. vol 6. issue 4. 2010-06-25. PMID:20442866. |
several inflammatory mediators, such as tumor necrosis factor alpha (tnf-alpha), nitric oxide and matrix metalloproteinases (mmps), contribute to this disruption. |
2010-06-25 |
2023-08-12 |
human |
| Sabrina Ganzinelli, Enri Borda, Leonor Sterin-Bord. Autoantibodies from schizophrenia patients induce cerebral cox-1/iNOS mRNA expression with NO/PGE2/MMP-3 production. The international journal of neuropsychopharmacology. vol 13. issue 3. 2010-06-24. PMID:19835666. |
we demonstrated that circulating antibodies from schizophrenia patients, which interact with cerebral m1 muscarinic acetylcholine receptors (m1 machrs), trigger production of nitric oxide (no), prostaglandin e2 (pge2) and matrix metalloproteinase-3 (mmp-3), and act as inducers of cyclooxygenase-1 (cox-1) and inducible nitric oxide synthase (inos) mrna expression in the rat frontal cortex. |
2010-06-24 |
2023-08-12 |
rat |
| Chia-Jui Weng, Gow-Chin Ye. The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis. Clinical & experimental metastasis. vol 27. issue 5. 2010-06-24. PMID:20461449. |
activation of these kinases subsequently inhibits the activity or expression of activator protein-1(ap-1) and nuclear factor-kappa b (nf-kappab), resulting in the down-regulation of urokinase plaminogen activator (upa), upa receptor (upar), matrix metalloproteinase (mmp)-9, vascular endothelial growth factor (vegf), transforming growth factor (tgf)-beta1, interleukin (il)-8, inducible nitric oxide (no) and beta1-integrin as shown in various cell lines or animal models. |
2010-06-24 |
2023-08-12 |
Not clear |