| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 |
the present study demonstrated for the first time that acute as well as subchronic (4\xe2\x80\xafdays) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3\xe2\x80\xafmg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the \xce\xb2-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). |
2023-03-04 |
2023-03-06 |
rat |
| In\\xc3\\xaas M Amaral, Laura Scheffauer, Angelika B Langeder, Alex Hofer, Rana El Rawa. Rewarding Social Interaction in Rats Increases CaMKII in the Nucleus Accumbens. Biomedicines vol 9 issue 12 2021 34944702 |
however, little is known about the contribution of camkii signaling in the nucleus accumbens (nac) in natural rewards such as social interaction. |
2021-12-24 |
2023-01-26 |
rat |
| In\\xc3\\xaas M Amaral, Laura Scheffauer, Angelika B Langeder, Alex Hofer, Rana El Rawa. Rewarding Social Interaction in Rats Increases CaMKII in the Nucleus Accumbens. Biomedicines vol 9 issue 12 2021 34944702 |
rewarding social interaction in rats increases camkii in the nucleus accumbens. |
2021-12-24 |
2023-01-26 |
rat |
| Conor H Murray, Andrew D Gaulden, Alex B Kawa, Mike Milovanovic, Aaron J Caccamise, Jonathan R Funke, Sachin Patel, Marina E Wol. CaMKII Modulates Diacylglycerol Lipase-\\xce\\xb1 Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving. eNeuro vol 8 issue 5 2021 34544759 |
camkii modulates diacylglycerol lipase-\xce\xb1 activity in the rat nucleus accumbens after incubation of cocaine craving. |
2021-10-20 |
2023-01-26 |
rat |
| Haniyeh Soltani, Mitra-Sadat Sadat-Shirazi, Bahareh Pakpour, Ghorbangol Ashabi, Mohammad-Reza Zarrindas. Toxic effect of calcium/calmodulin kinase II on anxiety behavior, neuronal firing and plasticity in the male offspring of morphine-abstinent rats. Behavioural brain research vol 395 issue 2021 32841609 |
according to the critical role of calcium/calmodulin protein kinaseii (camkii) in these processes, the present study examined the effect of camkii inhibitor (kn93) on neuronal activity and level of c-fos in the amygdala and nucleus accumbens (nac) in the offspring of morphine-exposed parents. |
2021-10-13 |
2023-01-26 |
rat |
| Mengnan Li, Xiaomin Zhang, Chongyang Li, Yanan Liu, Shuang Yang, Shilian X. Galanin Receptor 2 Is Involved in Galanin-Induced Analgesic Effect by Activating PKC and CaMKII in the Nucleus Accumbens of Inflammatory Pain Rats. Frontiers in neuroscience vol 14 issue 2021 33551722 |
galanin receptor 2 is involved in galanin-induced analgesic effect by activating pkc and camkii in the nucleus accumbens of inflammatory pain rats. |
2021-02-10 |
2023-01-26 |
rat |
| Yu-Gang Lu, Long Wang, Jiang-Long Chen, Jiao Zhu, Xiao-Yan Meng, Zhen-Dong You, Wei-Feng Y. Projections from lateral habenular to tail of ventral tegmental area contribute to inhibitory effect of stress on morphine-induced conditioned place preference. Brain research vol 1717 issue 2020 30914248 |
meanwhile, we detected the expression of darpp-32 phosphorylation (p-darpp-32) in the nucleus accumbens (nac), and camkii in lhb. |
2020-09-24 |
2023-01-26 |
rat |
| Michael C Salling, Christopher J Hodge, Kelly E Psilos, Vallari R Eastman, Sara P Faccidomo, Clyde W Hodg. Cue-induced reinstatement of alcohol-seeking behavior is associated with increased CaMKII T286 phosphorylation in the reward pathway of mice. Pharmacology, biochemistry, and behavior vol 163 issue 2018 29100991 |
a variety of plasticity events require activation of calcium calmodulin-dependent protein kinase ii (camkii) in components of the reward pathway, such as the nucleus accumbens and amygdala. |
2018-07-10 |
2023-01-26 |
mouse |
| Kia J Jackson, Pretal P Muldoon, Carrie Walters, Mohamad Imad Dama. Neuronal calcium/calmodulin-dependent protein kinase II mediates nicotine reward in the conditioned place preference test in mice. Behavioural pharmacology vol 27 issue 1 2016 26292186 |
further, we assessed camkii activity in the ventral tegmental area (vta), nucleus accumbens (nac), prefrontal cortex, and hippocampus after nicotine cpp and found significant increases in camkii activity in the mouse vta and nac that were blocked by camkii antagonists. |
2016-09-19 |
2023-01-25 |
mouse |
| A J Robison, Vincent Vialou, Hao-Sheng Sun, Benoit Labonte, Sam A Golden, Caroline Dias, Gustavo Turecki, Carol Tamminga, Scott Russo, Michelle Mazei-Robison, Eric J Nestle. Fluoxetine epigenetically alters the CaMKII\\xce\\xb1 promoter in nucleus accumbens to regulate \\xce\\x94FosB binding and antidepressant effects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 39 issue 5 2014 24240473 |
recent work in addiction models demonstrates that the transcription factor \xce\x94fosb and protein kinase calmodulin-dependent protein kinase ii (camkii) are co-regulated in nucleus accumbens (nac), a brain reward region implicated in both addiction and depression models including social defeat. |
2014-12-01 |
2023-01-25 |
mouse |
| Xiaojie Liu, Yong Liu, Peng Zhong, Brianna Wilkinson, Jinshun Qi, Christopher M Olsen, K Ulrich Bayer, Qing-song Li. CaMKII activity in the ventral tegmental area gates cocaine-induced synaptic plasticity in the nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 39 issue 4 2014 24154664 |
camkii activity in the ventral tegmental area gates cocaine-induced synaptic plasticity in the nucleus accumbens. |
2014-10-10 |
2023-01-25 |
Not clear |
| Kia J Jackson, M Imad Dama. Beta2-containing nicotinic acetylcholine receptors mediate calcium/calmodulin-dependent protein kinase-II and synapsin I protein levels in the nucleus accumbens after nicotine withdrawal in mice. European journal of pharmacology vol 701 issue 1-3 2013 23313759 |
results show that phosphorylated and total camkii and synapsin i protein levels were significantly increased in the nucleus accumbens after chronic nicotine infusion, and reduced after treatment with dh\xce\xb2e, but not mla. |
2013-08-22 |
2023-01-25 |
mouse |
| Jessica A Loweth, Dongdong Li, James J Cortright, Georgia Wilke, Okunola Jeyifous, Rachael L Neve, K Ulrich Bayer, Paul Vezin. Persistent reversal of enhanced amphetamine intake by transient CaMKII inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 33 issue 4 2013 23345217 |
amphetamine exposure transiently increases ca(2+)/calmodulin-dependent protein kinase ii (camkii) \xce\xb1 expression in the nucleus accumbens (nacc) shell and this persistently increases local glua1 s831 phosphorylation and enhances behavioral responding to the drug. |
2013-03-20 |
2023-01-25 |
rat |
| Zhuo Liu, Xiao-Dong Liu, Jian-Jun Zhang, Long-Chuan Y. Increases in \\xce\\xb1CaMKII phosphorylated on Thr286 in the nucleus accumbens shell but not the core during priming-induced reinstatement of morphine-seeking in rats. Neuroscience letters vol 526 issue 1 2012 22884929 |
in this study, we detected the changes of camkii protein levels in the nucleus accumbens (nac), a key nucleus involved in drug-reward, during the reinstatement of morphine-seeking behavior with animal model of morphine self-administration in rats. |
2012-12-10 |
2023-01-25 |
rat |
| Zhuo Liu, Jian-Jun Zhang, Xiao-Dong Liu, Long-Chuan Y. Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Neuroscience letters vol 518 issue 2 2012 22579819 |
here, we explored the roles of camkii in the nucleus accumbens (nac) shell in the extinction and reinstatement of morphine-seeking behavior. |
2012-10-04 |
2023-01-25 |
rat |
| Sa\\xc3\\xafd Kourrich, Jason R Klug, Mark Mayford, Mark J Thoma. AMPAR-independent effect of striatal \\xce\\xb1CaMKII promotes the sensitization of cocaine reward. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 32 issue 19 2012 22573680 |
while behavior in rodent addiction models is linked with camkii activity in the nucleus accumbens (nac) shell, the key cellular adaptations that forge this link are unclear. |
2012-07-06 |
2023-01-25 |
mouse |
| Kazumi Yoshizawa, Minoru Narita, Mai Saeki, Michiko Narita, Kana Isotani, Hiroshi Horiuchi, Satoshi Imai, Naoko Kuzumaki, Tsutomu Suzuk. Activation of extracellular signal-regulated kinase is critical for the discriminative stimulus effects induced by U-50,488H. Synapse (New York, N.Y.) vol 65 issue 10 2012 21465566 |
the levels of immunoreactivity of phosphorylated p38 mapk and phosphorylated calcium/calmodulin-dependent protein kinase ii (camkii) were significantly increased in the nucleus accumbens and amygdala in lever-press, yoked and discrimination groups compared to a naive group. |
2012-05-30 |
2023-01-25 |
rat |
| Jessica A Loweth, Bryan F Singer, Lorinda K Baker, Georgia Wilke, Hidetoshi Inamine, Nancy Bubula, John K Alexander, William A Carlezon, Rachael L Neve, Paul Vezin. Transient overexpression of alpha-Ca2+/calmodulin-dependent protein kinase II in the nucleus accumbens shell enhances behavioral responding to amphetamine. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 30 issue 3 2010 20089902 |
ca(2+)/calmodulin-dependent protein kinase ii (camkii) is known to contribute to the expression of psychostimulant sensitization by regulating dopamine (da) overflow from da neuron terminals in the nucleus accumbens (nacc). |
2010-02-05 |
2023-01-25 |
rat |
| K J Jackson, C L Walters, M I Dama. Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo. The Journal of pharmacology and experimental therapeutics vol 330 issue 2 2009 19435931 |
we first show that administration of nicotine increases camkii activity in the ventral tegmental area (vta), nucleus accumbens (nac), and amygdala. |
2009-08-19 |
2023-01-25 |
mouse |
| Jessica A Loweth, Lorinda K Baker, Tarra Guptaa, Anitra M Guillory, Paul Vezin. Inhibition of CaMKII in the nucleus accumbens shell decreases enhanced amphetamine intake in sensitized rats. Neuroscience letters vol 444 issue 2 2008 18694805 |
microinjection of the calcium/calmodulin-dependent protein kinase ii (camkii) inhibitor kn-93 into the nucleus accumbens (nacc) shell impairs expression of the sensitized locomotion and nacc dopamine (da) overflow normally observed in psychostimulant-exposed rats. |
2008-11-18 |
2023-01-25 |
rat |