All Relations between nucleus accumbens and nac

Reference Sentence Publish Date Extraction Date Species
Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior vol issue 2023 36870422 the present study demonstrated for the first time that acute as well as subchronic (4\xe2\x80\xafdays) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3\xe2\x80\xafmg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the \xce\xb2-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). 2023-03-04 2023-03-06 rat
Soren D Emerson, Maxime Chev\\xc3\\xa9e, Philipp Mews, Erin S Calipar. The transcriptional response to acute cocaine is inverted in male mice with a history of cocaine self-administration and withdrawal throughout the mesocorticolimbic system. Molecular and cellular neurosciences vol issue 2023 36868542 in this study, we utilized rna sequencing to characterize how the transcriptome-wide effects of acute cocaine exposure were altered by a history of cocaine self-administration and long-term withdrawal (30\xe2\x80\xafdays) in the ventral tegmental area (vta), nucleus accumbens (nac), and prefrontal cortex (pfc) in male mice. 2023-03-03 2023-03-06 mouse
Parviz Dousti Kataj, Nasim Vousooghi, Mahmoud Reza Hadjighassem, Maryam Farahmandfar, Somayeh Ebrahimi-Baroug. Evaluation of the effect of mesenchymal stem cells injection in the nucleus accumbens on the morphine reinstatement behavior in a conditioned place preference model in Wistar rat: expression changes of NMDA receptor subunits and NT-3. Behavioural brain research vol issue 2023 36854364 this study was designed to discover the effect of mscs injection in the nucleus accumbens (nac) on the reinstatement of behavior in morphine-induced conditioned place preference (cpp) in male rats. 2023-02-28 2023-03-06 rat
Yun Zhou, Qingxiao Hong, Wenjin Xu, Weisheng Chen, Xiaohu Xie, Dingding Zhuang, Miaojun Lai, Dan Fu, Zemin Xu, Majie Wang, Wenhua Zhou, Huifen Li. Differential expression profiling of tRNA-Derived small RNAs and their potential roles in methamphetamine self-administered rats. Frontiers in genetics vol 14 issue 2023 36845381 in this study, we used a combination of small rna sequencing, quantitative reverse transcription-polymerase chain reaction (qrt\xe2\x80\x92pcr), bioinformatics, and luciferase reporter assays to screen the expression profiles and identify the functional roles of trfs and tirnas in the nucleus accumbens (nac) of methamphetamine self-administration rat models. 2023-02-27 2023-03-06 rat
Csaba Vadasz, Beatrix M Gyetva. Genetic association of nucleus accumbens 5-hydroxyindoleacetic acid level and alcohol preference drinking in a quasi-congenic male mice: Potential modulation by Drug and alcohol dependence reports vol 2 issue 2023 36845900 genetic association of nucleus accumbens 5-hydroxyindoleacetic acid level and alcohol preference drinking in a quasi-congenic male mice: potential modulation by to test the hypothesis that predisposition to high alcohol drinking behavior is genetically associated with hypoactive serotonergic function in the nucleus accumbens (nac). 2023-02-27 2023-03-06 mouse
Eric Y Choi, Daniela Franco, Catherine A Stapf, Madeleine Gordin, Amanda Chow, Kara K Cover, Ramesh Chandra, Mary Kay Lob. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. The Journal of neuroscience : the official journal of the Society for Neuroscience vol issue 2023 36849419 the nucleus accumbens (nac) is a major brain hub mediating reward behavior. 2023-02-27 2023-03-06 Not clear
Matthew T Birnie, Annabel K Short, Gregory B de Carvalho, Lara Taniguchi, Benjamin G Gunn, Aidan L Pham, Christy A Itoga, Xiangmin Xu, Lulu Y Chen, Stephen V Mahler, Yuncai Chen, Tallie Z Bara. Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice. Nature communications vol 14 issue 1 2023 36841826 we characterize a stress-sensitive projection connecting basolateral amygdala (bla) and nucleus accumbens (nac) that co-expresses gaba and the stress-reactive neuropeptide corticotropin-releasing hormone (crh). 2023-02-25 2023-03-06 mouse
Sara Guarino, Christopher Hagen, Quynh Nguyen, Mauricio R Papin. Frustrative nonreward and the basal ganglia: Chemogenetic inhibition and excitation of the nucleus accumbens and globus pallidus externus during reward downshift. Neurobiology of learning and memory vol issue 2023 36822464 these experiments explored the role of the basal ganglia in crd using inhibitory and excitatory dreadds (designer receptors exclusively activated by designer drugs) infused in either the nucleus accumbens (nac) or one of its downstream targets, the globus pallidus externus (gpe). 2023-02-23 2023-03-06 Not clear
Diana M Cort\\xc3\\xa9s-Pati\\xc3\\xb1o, Hans Ballesteros-Acosta, Valentyna Martin Neira, David Rikardo P\\xc3\\xa9rez Contreras, Marisol R Lampre. Post-weaning social isolation increases the incentive value of nicotine-related contexts and decreases the accumulation of \\xce\\x94FosB in nucleus accumbens in adolescent rats. Pharmacology, biochemistry, and behavior vol issue 2023 36805863 the current study evaluated the effects of differential rearing conditions during adolescence (isolation or group rearing) on (1) conditioned place preference induced by low nicotine doses (0.1 or 0.3\xe2\x80\xafmg/kg) and (2) sensitization to the locomotor effects of nicotine after sub-chronic administration (3) and accumulation of \xce\x94fosb in nucleus accumbens (nac). 2023-02-22 2023-03-06 rat
Matthew R Irwin, Carlos M Curay, Shinbe Choi, Eugene A Kiyatki. Basic metabolic and vascular effects of ketamine and its interaction with fentanyl. Neuropharmacology vol issue 2023 36801400 by using multi-site thermorecording in freely-moving rats, we showed that intravenous ketamine at a range of human relevant doses (3, 9, 27\xe2\x80\xafmg/kg) dose-dependently increases locomotor activity and brain temperature, as assessed in the nucleus accumbens (nac). 2023-02-21 2023-03-06 rat
Tyson R Baird, Kimberly N Karin, Samuel A Marsh, F Ivy Carroll, J M L Medina-Contreras, S Stevens Negus, Jose M Elti. Rate of onset of dopamine transporter inhibitors assessed with intracranial self-stimulation and in vivo dopamine photometry in rats. Psychopharmacology vol issue 2023 36802016 additionally, in vivo photometry using the fluorescent da sensor dlight1.1 targeted to the nucleus accumbens (nac) was used to assess the time course of extracellular da levels as a neurochemical correlate of behavioral effects. 2023-02-21 2023-03-06 rat
Hillary A Wadsworth, Elizabeth Q Anderson, Benjamin M Williams, Joakim W Ronstr\\xc3\\xb6m, Janna K Moen, Anna M Lee, J Michael McIntosh, Jie Wu, Jordan T Yorgason, Scott C Steffense. Role of \\xce\\xb16-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. Molecular neurobiology vol issue 2023 36802012 the prevailing view is that enhancement of dopamine (da) transmission in the mesolimbic system, consisting of da neurons in the ventral tegmental area (vta) that project to the nucleus accumbens (nac), underlies the reward properties of ethanol (etoh) and nicotine (nic). 2023-02-21 2023-03-06 mouse
Staci Bilbo, Caroline Smith, Danielle Rendina, Marcy Kingsbury, Karen Malacon, Dang Nguyen, Jessica Tran, Benjamin Devlin, Ravikiran Raju, Madeline Clark, Lauren Burgett, Jason Zhang, Murat Cetinbas, Ruslan Sadreyev, Kevin Chen, Malvika Iye. Microbial modulation prevents the effects of pervasive environmental stressors on microglia and social behavior, but not the dopamine system. Research square vol issue 2023 36798238 these behavioral deficits are accompanied by changes in microglial morphology and gene expression as well as decreased dopamine receptor expression and dopaminergic fiber input in the nucleus accumbens (nac). 2023-02-17 2023-03-06 mouse
Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience vol 17 issue 2023 36793536 cocaine's addictive properties stem from its capacity to increase tonic extracellular dopamine levels in the nucleus accumbens (nac). 2023-02-16 2023-03-06 rat
Maik Derksen, Birte Zuidinga, Marijke van der Veer, Valerie Rhemrev, Linda Jolink, Liesbeth Reneman, Aart Nederveen, Birte Forstmann, Matthijs Feenstra, Ingo Willuhn, Damiaan Deny. A comparison of how deep brain stimulation in two targets with anti-compulsive efficacy modulates brain activity using fMRI in awake rats. Psychiatry research. Neuroimaging vol 330 issue 2023 36796237 bold-signal intensity was measured in five regions of interest (rois): medial and orbital prefrontal cortex, nucleus accumbens (nac), ic area, and mediodorsal thalamus. 2023-02-16 2023-03-06 rat
Jonathan R Funke, Eun-Kyung Hwang, Amanda M Wunsch, Raines Baker, Kimberley A Engeln, Conor H Murray, Mike Milovanovic, Aaron J Caccamise, Marina E Wol. Persistent neuroadaptations in the nucleus accumbens core accompany incubation of methamphetamine craving in male and female rats. eNeuro vol issue 2023 36792361 second, using whole-cell patch-clamp recordings in medium spiny neurons (msns) of the nucleus accumbens (nac) core, we assessed synaptic levels of calcium-permeable ampa receptors (cp-ampars), as their elevation is required for expression of incubation in males. 2023-02-15 2023-03-06 rat
Scott Russo, Flurin Cathomas, Hsiao-Yun Lin, Kenny Chan, Long Li, Romain Durand-de Cuttoli, Lyonna Parise, Antonio Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo, Aarthi Ramakrishnan, Molly Estill, Carmen Ferrer-Perez, Eric Parise, Jun Wang, Allison Sowa, William Janssen, Sara Costi, Adeeb Rahman, Nicolas Fernandez, Filip Swirski, Eric Nestler, Li Shen, Miriam Merad, James Murroug. Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility. Research square vol issue 2023 36778505 in mice, we show that this increase leads to alterations in extracellular space and neurophysiological changes in the nucleus accumbens (nac), thereby altering social behaviour. 2023-02-13 2023-03-06 mouse
Alexis N Jameson, Justin K Siemann, James Melchior, Erin S Calipari, Douglas G McMahon, Brad A Gruete. Photoperiod Impacts Nucleus Accumbens Dopamine Dynamics. eNeuro vol issue 2023 36781229 mesolimbic dopamine input to the nucleus accumbens (nac) contributes to the regulation of affective state and behaviors. 2023-02-13 2023-03-06 mouse
Shigetaka Kawashima, Fan Lou, Ikue Kusumoto-Yoshida, Liying Hao, Tomoyuki Kuwak. Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice. Scientific reports vol 13 issue 1 2023 36781929 in our previous study using chemogenetic techniques in narcoleptic mice (orexin neuron-ablated mice), we found that the rostral nucleus accumbens (nac) shell is needed for chocolate-induced cataplexy. 2023-02-13 2023-03-06 mouse
Qing Zhai, Ariful Islam, Bin Chen, Hengsen Zhang, Do Huu Chi, Md Al Mamun, Yutaka Takahashi, Noriko Sato, Hidenori Yamasue, Yoshiki Nakajima, Yu Nagashima, Fumito Sano, Tomohito Sato, Tomoaki Kahyo, Mitsutoshi Seto. Endocannabinoid 2-Arachidonoylglycerol Levels in the Anterior Cingulate Cortex, Caudate Putamen, Nucleus Accumbens, and Piriform Cortex Were Upregulated by Chronic Restraint Stress. Cells vol 12 issue 3 2023 36766735 however, the detailed spatial distribution of 2-ag and its changes by crs in stress processing-related anatomical structures such as the anterior cingulate cortex (acc), caudate putamen (cp), nucleus accumbens (nac), and piriform cortex (pir) are still unclear. 2023-02-11 2023-03-06 mouse