| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kevin Braunscheidel, Michael Okas, John J Woodwar. Toluene alters the intrinsic excitability and excitatory synaptic transmission of basolateral amygdala neurons. Frontiers in neuroscience. vol 18. 2024-04-10. PMID:38595974. |
however, studies from our lab and others have begun to reveal how inhalants such as the organic solvent toluene affect neurons in key addiction related areas of the brain including the ventral tegmental area, nucleus accumbens and medial prefrontal cortex. |
2024-04-10 |
2024-04-12 |
Not clear |
| Chengmei Yang, Xiaoyu Chen, Jingyang Xu, Weihai Che. SKF82958, a dopamine D1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in C57BL/6J mice. Behavioural pharmacology. 2024-04-03. PMID:38567425. |
skf82958, a dopamine d1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in c57bl/6j mice. |
2024-04-03 |
2024-04-05 |
mouse |
| Chengmei Yang, Xiaoyu Chen, Jingyang Xu, Weihai Che. SKF82958, a dopamine D1 receptor agonist, disrupts prepulse inhibition in the medial prefrontal cortex and nucleus accumbens in C57BL/6J mice. Behavioural pharmacology. 2024-04-03. PMID:38567425. |
overall, the study suggests that the nucleus accumbens and medial prefrontal cortex are responsible for the ppi-disruptive effect of dopamine d1 receptor agonists. |
2024-04-03 |
2024-04-05 |
mouse |
| Shelby Travaglianti, Ahmed Alotaibi, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically to ethanol. Brain research bulletin. 2024-04-03. PMID:38570076. |
chronic ethanol consumption can lead to increased extracellular glutamate concentrations in key reward brain regions, such as medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and consequently leading to oxidative stress and neuroinflammation. |
2024-04-03 |
2024-04-06 |
rat |
| Qiong Luo, Jing Luo, Xixi Wang, Sifei Ga. Restoration of the Activity of the Prefrontal Cortex to the Nucleus Accumbens Core Pathway Relieves Fentanyl-Induced Hyperalgesia in Male Rats. Journal of pain research. vol 17. 2024-03-25. PMID:38524691. |
functional connectivity between the prelimbic medial prefrontal cortex (pl-mpfc) and the core of the nucleus accumbens (nac core) predicts pain chronification. |
2024-03-25 |
2024-03-27 |
rat |
| Tsun Hay Jason Ng, Mohammed H Sarikahya, Roger Hudson, Hanna J Szkudlarek, Enzo Pérez-Valenzuela, Taygun C Uzuneser, Emma Proud, Dana Gummerson, Miray Youssef, Madeline Machado, Kuralay Zhaksylyk, Marieka V DeVuono, Chaochao Chen, Ken K-C Yeung, Walter J Rushlow, Steven R Laviolett. Adolescent nicotine exposure induces long-term, sex-specific disturbances in mood and anxiety-related behavioral, neuronal and molecular phenotypes in the mesocorticolimbic system. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-03-24. PMID:38521861. |
specifically, brain regions such as the medial prefrontal cortex (mpfc), the ventral tegmental area (vta), nucleus accumbens (nac) and hippocampus, are implicated in both nicotine dependence and pathological phenotypes linked to mood and anxiety disorders. |
2024-03-24 |
2024-03-26 |
rat |
| Ioannis Bakoyiannis, Eva Gunnel Ducourneau, Mateo N'diaye, Alice Fermigier, Celine Ducroix-Crepy, Clementine Bosch-Bouju, Etienne Coutureau, Pierre Trifilieff, Guillaume Ferreir. Obesogenic diet induces circuit-specific memory deficits in mice. eLife. vol 13. 2024-03-04. PMID:38436653. |
here, we used an intersectional viral approach in hfd-fed male mice to chemogenetically inactivate specific vhpc efferent pathways to nucleus accumbens (nac) or medial prefrontal cortex (mpfc) during memory tasks. |
2024-03-04 |
2024-03-06 |
mouse |
| Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamuler. Brief exposure to enriched environment rapidly shapes the glutamate synapses in the rat brain: A metaplastic fingerprint. The European journal of neuroscience. 2024-02-20. PMID:38378276. |
adult male sprague-dawley rats were exposed to ee for 22 h and the expression of critical elements of the glutamate synapse was measured 2 h after the end of ee in the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and hippocampus (hipp) brain areas, which are critical for reward and memory. |
2024-02-20 |
2024-02-23 |
rat |
| Cameron J Davidson, John H Hannigan, Shane A Perrine, Scott E Bowe. Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. Neurotoxicology and teratology. 2024-01-10. PMID:38199311. |
analysis of monoamines and their metabolites using high pressure liquid chromatography (hplc) within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dstr), and ventral tegmental area (vta) revealed subtle effects on monoamine or metabolite levels following cumulative dosing that varied by drug (cocaine and ethanol) and abstinence duration. |
2024-01-10 |
2024-01-13 |
mouse |
| Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Brain structure & function. 2024-01-09. PMID:38193917. |
novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). |
2024-01-09 |
2024-01-10 |
rat |
| Emanuele Claudio Latagliata, Cristina Orsini, Simona Cabib, Francesca Biagioni, Francesco Fornai, Stefano Puglisi-Allegr. Prefrontal Dopamine in Flexible Adaptation to Environmental Changes: A Game for Two Players. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137410. |
the reviewed findings point to a role of catecholaminergic transmission in the medial prefrontal cortex (mpfc) in modulating da's availability in the nucleus accumbens (nac), as well as a role of nac da in modulating the motivational value of natural and conditioned stimuli. |
2023-12-23 |
2023-12-25 |
Not clear |
| Ki Bum Um, Soyoung Kwak, Sun-Ha Cheon, JuHyun Kim, Su-Kyeong Hwan. AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137504. |
the core symptoms of asd are associated with deficits in mesocorticolimbic dopamine pathways that project from the ventral tegmental area (vta) to the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2023-12-23 |
2023-12-25 |
mouse |
| Luis Gerardo Balcazar-Ochoa, Rosa Ventura-Martínez, Guadalupe Esther Ángeles-López, Claudia Gómez-Acevedo, Omar Francisco Carrasco, Raúl Sampieri-Cabrera, Anahí Chavarría, Abimael González-Hernánde. Clavulanic Acid and its Potential Therapeutic Effects on the Central Nervous System. Archives of medical research. vol 55. issue 1. 2023-12-01. PMID:38039802. |
studies have revealed that clav can increase glt-1 expression in the nucleus accumbens (nacc), medial prefrontal cortex (pfc), and spinal cord of rodents, to affect glutamate and dopaminergic neurotransmission, and exert an anti-inflammatory effect by modulating the levels of the cytokines tnf-α and interleukin 10 (il-10). |
2023-12-01 |
2023-12-10 |
Not clear |
| Bing Huang, Zifei Chen, Fang Huang, Fenfei Gao, Jieling Chen, Peipei Liu, Zhijie Lu, Weiyuan Chen, Jie W. Demyelination in the medial prefrontal cortex by withdrawal from chronic nicotine causes impaired cognitive memory. Progress in neuro-psychopharmacology & biological psychiatry. 2023-11-30. PMID:38036034. |
we found no effect of nicotine withdrawal on the myelination in both of the ventral tegmental area (vta) and nucleus accumbens (nac) regions, but unexpectedly, we observed a demyelination phenomenon in the medial prefrontal cortex (mpfc) after withdrawal from chronic nicotine. |
2023-11-30 |
2023-12-10 |
Not clear |
| Yong-Qing Zhang, Hyun Kyu Min, Eunchong Hong, Eunhye Yu, Sun Mi Gu, Seong Shoon Yoon, Dohyun Lee, Jaejun Lee, Jin Tae Hong, Jaesuk Yu. Abused drug-induced intracranial self-stimulation is correlated with the alteration of dopamine transporter availability in the medial prefrontal cortex and nucleus accumbens of mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 169. 2023-11-10. PMID:37948992. |
abused drug-induced intracranial self-stimulation is correlated with the alteration of dopamine transporter availability in the medial prefrontal cortex and nucleus accumbens of mice. |
2023-11-10 |
2023-11-20 |
mouse |
| Yong-Qing Zhang, Hyun Kyu Min, Eunchong Hong, Eunhye Yu, Sun Mi Gu, Seong Shoon Yoon, Dohyun Lee, Jaejun Lee, Jin Tae Hong, Jaesuk Yu. Abused drug-induced intracranial self-stimulation is correlated with the alteration of dopamine transporter availability in the medial prefrontal cortex and nucleus accumbens of mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 169. 2023-11-10. PMID:37948992. |
we determined dopamine transporter (dat) availability in the medial prefrontal cortex (mpfc), striatum, and nucleus accumbens (nac) after drug treatment. |
2023-11-10 |
2023-11-20 |
mouse |
| Joseph S Lonstein, Erika M Vitale, Doris Olekanma, Andrew McLocklin, Nathan Pence, Remco Bredewold, Alexa H Veenema, Alexander W Johnson, S Alexandra Bur. Anxiety, aggression, reward sensitivity, and forebrain dopamine receptor expression in a laboratory rat model of early-life disadvantage. Developmental psychobiology. vol 65. issue 7. 2023-10-20. PMID:37860907. |
d1 and d2 receptor mrna in the medial prefrontal cortex and nucleus accumbens (nac) were each affected by the early-life treatments and differently between the sexes. |
2023-10-20 |
2023-11-08 |
rat |
| Eliza M Greiner, Mary E Witt, Stephanie J Moran, Gorica D Petrovic. Activation patterns in male and female forebrain circuitries during food consumption under novelty. Research square. 2023-10-04. PMID:37790415. |
novel context induced fos robustly in almost every region analyzed, including the central (cea) and basolateral complex nuclei of the amygdala, the thalamic paraventricular (pvt) and reuniens nuclei, the nucleus accumbens (acb), the medial prefrontal cortex prelimbic and infralimbic areas, and the dorsal agranular insular cortex (ai). |
2023-10-04 |
2023-10-07 |
rat |
| Désirée R Seib, Daniel J Tobiansky, John Meitzen, Stan B Floresco, Kiran K Som. Neurosteroids and the mesocorticolimbic system. Neuroscience and biobehavioral reviews. 2023-08-11. PMID:37567491. |
this circuit includes dopaminergic projections from the ventral tegmental area to the nucleus accumbens and medial prefrontal cortex. |
2023-08-11 |
2023-08-16 |
Not clear |
| Giuseppe Tringali, Gianluca Lavanco, Valentina Castelli, Giuseppe Pizzolanti, Martin Kuchar, Diego Currò, Carla Cannizzaro, Anna Brancat. Cannabidiol tempers alcohol intake and neuroendocrine and behavioural correlates in alcohol binge drinking adolescent rats. Focus on calcitonin gene-related peptide's brain levels. Phytotherapy research : PTR. 2023-08-01. PMID:37525534. |
adolescent male rats underwent the intermittent 20% alcohol two-bottle choice paradigm; at the binge day (bd) and the 24 h withdrawal day (wd), we assessed cgrp expression in medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala, hypothalamus and brainstem; in addition, we evaluated sucrose preference, social motivation and drive, nociceptive response, and serum corticosterone levels. |
2023-08-01 |
2023-08-14 |
rat |