All Relations between nucleus accumbens and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Courtney S Wilkinson, Harrison L Blount, Marek Schwendt, Lori A Knacksted. Brain Monoamine Dysfunction in Response to Predator Scent Stress Accompanies Stress-Susceptibility in Female Rats. Biomolecules. vol 13. issue 7. 2023-07-29. PMID:37509091. using a predator scent stress (pss) rodent model of ptsd, we sought to determine if stress-susceptible female rats show altered monoamine concentrations in brain regions associated with ptsd: the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and dorsal (dhipp) and ventral (vhipp) hippocampus. 2023-07-29 2023-08-14 rat
Julie-Anne Balouek, Christabel A Mclain, Adelaide R Minerva, Rebekah L Rashford, Shannon N Bennett, Forrest D Rogers, Catherine Jensen Peñ. Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-10. PMID:37429717. we found that in both male and female mice, els-activated neurons within the nucleus accumbens (nac), and to a lesser-extent the medial prefrontal cortex, were preferentially reactivated by adult stress. 2023-07-10 2023-08-14 mouse
Yuan-Yuan Han, Jian-Wen Zhou, Zhi-Wei Guo, Zhuo-Qing Wu, Zai-Yong Zhang, De-Xiang Liu, Cheng Lon. Multiple brain regions are involved in reaction to acute restraint stress in CYLD-knockout mice. Stress (Amsterdam, Netherlands). vol 26. issue 1. 2023-07-03. PMID:37395260. here we report that cyld deficiency leads to an unexpected reaction to ars in mice, and is accompanied by significant neuronal activation of brain regions including the medial prefrontal cortex (mpfc), dorsal striatum (ds), nucleus accumbens (nac), and basal lateral amygdala (bla), but not ventral hippocampus (vhpc). 2023-07-03 2023-08-14 mouse
Robert J McDonald, Nancy S Hong, Carlie Germaine, Bryan Kol. Peripherally-administered amphetamine induces plasticity in medial prefrontal cortex and nucleus accumbens in rats with amygdala lesions: implications for neural models of memory modulation. Frontiers in behavioral neuroscience. vol 17. 2023-06-27. PMID:37358968. peripherally-administered amphetamine induces plasticity in medial prefrontal cortex and nucleus accumbens in rats with amygdala lesions: implications for neural models of memory modulation. 2023-06-27 2023-08-14 rat
Wei-Zhu Liu, Chun-Yan Wang, Yu Wang, Mei-Ting Cai, Wei-Xiang Zhong, Tian Liu, Zhi-Hao Wang, Han-Qing Pan, Wen-Hua Zhang, Bing-Xing Pa. Circuit- and laminar-specific regulation of medial prefrontal neurons by chronic stress. Cell & bioscience. vol 13. issue 1. 2023-05-19. PMID:37208769. the medial prefrontal cortex (mpfc) is a hub for controlling stress responses through communicating with multiple limbic structures, including the basolateral amygdala (bla) and nucleus accumbens (nac). 2023-05-19 2023-08-14 Not clear
F Javier Rubio, Daniel E Olivares, Christopher Dunn, Shiliang Zhang, Elias M Hilaire, Akeem Henry, Carlos Mejias-Aponte, Carlos J Nogueras-Ortiz, Pooja V Selvam, Fabio C Cruz, Rajtarun Madangopal, Marisela Morales, Bruce T Hop. Flow cytometry of synaptoneurosomes (FCS) reveals increased ribosomal S6 and calcineurin proteins in activated medial prefrontal cortex to nucleus accumbens synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-09. PMID:37160369. after injecting yfp-expressing aav into medial prefrontal cortex (mpfc) to label terminals in nucleus accumbens (nac) of rats, we injected 20 mg/kg of cocaine in a novel context (cocaine+novelty) to activate synapses, and prepared nac synaptoneurosomes 0-60 min following injections. 2023-05-09 2023-08-14 rat
María Del Mar Cajiao-Manrique, Rafael Maldonado, Elena Martín-Garcí. A male mouse model of WIN 55,212-2 self-administration to study cannabinoid addiction. Frontiers in pharmacology. vol 14. 2023-04-13. PMID:37050910. this model included the chemogenetic inhibition of neuronal activity in the medial prefrontal cortex to the nucleus accumbens pathway to assess the neurobiological substrate of cannabinoid addiction. 2023-04-13 2023-08-14 mouse
James W M Kang, Kevin A Keay, Michael D Kendig, Laura H Corbit, David Mo. Serotonin and Dopamine Show Different Response Profiles to Acute Stress in the Nucleus Accumbens and Medial Prefrontal Cortex of Rats with Neuropathic Pain. Neurochemical research. 2023-03-21. PMID:36941432. serotonin and dopamine show different response profiles to acute stress in the nucleus accumbens and medial prefrontal cortex of rats with neuropathic pain. 2023-03-21 2023-08-14 rat
James W M Kang, Kevin A Keay, Michael D Kendig, Laura H Corbit, David Mo. Serotonin and Dopamine Show Different Response Profiles to Acute Stress in the Nucleus Accumbens and Medial Prefrontal Cortex of Rats with Neuropathic Pain. Neurochemical research. 2023-03-21. PMID:36941432. by contrast, restraint stress acutely increased dopamine in the medial prefrontal cortex, and the nucleus accumbens; and increased serotonin in the medial prefrontal cortex 2 h later. 2023-03-21 2023-08-14 rat
James W M Kang, Kevin A Keay, Michael D Kendig, Laura H Corbit, David Mo. Serotonin and Dopamine Show Different Response Profiles to Acute Stress in the Nucleus Accumbens and Medial Prefrontal Cortex of Rats with Neuropathic Pain. Neurochemical research. 2023-03-21. PMID:36941432. in addition, these data suggest that the impact of nerve injury and acute stress on outcome-devaluation occurs independently of dopaminergic and serotonergic transmission in the medial prefrontal cortex, orbital prefrontal cortex and nucleus accumbens of rats. 2023-03-21 2023-08-14 rat
Marek Lapka, Chrysostomos Charalambous, Anna Khryakova, Alina Certilina, Jiri Novotny, Lucie Hejnova, Magdalena Sustkova-Fiserov. Ghrelin/GHS-R1A antagonism in memory test and its effects on central molecular signaling involved in addiction in rats. Pharmacology, biochemistry, and behavior. 2023-03-04. PMID:36870422. the present study demonstrated for the first time that acute as well as subchronic (4 days) administration of the experimental ghs-r1a antagonist jmv2959 in usual intraperitoneal doses including 3 mg/kg, had no influence on memory functions tested in the morris water maze in rats as well as no significant effects on the molecular markers linked with memory processing in selected brain areas in rats, specifically on the β-actin, c-fos, two forms of the calcium/calmodulin-dependent protein kinase ii (camkii, p-camkii) and the camp-response element binding protein (creb, p-creb), within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum, and hippocampus (hipp). 2023-03-04 2023-08-14 rat
Chen Yin Ou, Ying Hao Yu, Chi-Wen Wu, Anna Kozłowska, Bai-Chung Shyu, Andrew Chih Wei Huan. Neuronal activity of the medial prefrontal cortex, nucleus accumbens, and basolateral amygdala in conditioned taste aversion and conditioned place preference induced by different doses of morphine administrations in rats. Frontiers in pharmacology. vol 14. 2023-02-10. PMID:36762112. to re-examine the paradoxical effect hypothesis of abused drugs, the present study concerned whether different doses of morphine disparately affect neuronal activity and associations among the subareas of the medial prefrontal cortex (mpfc: cingulate cortex 1-cg1, prelimbic cortex-prl, infralimbic cortex-il), the subregions of the nucleus accumbens (nac; both core and shell), and the basolateral amygdala (bla) following conditioned taste aversion (cta) and conditioned place preference (cpp). 2023-02-10 2023-08-14 rat
Johnathan M Borland, Desarae A Dempsey, Anna C Peyla, Megan A L Hall, Abigail L Kohut-Jackson, Paul G Mermelstein, Robert L Meise. Aggression Results in the Phosphorylation of ERK1/2 in the Nucleus Accumbens and the Dephosphorylation of mTOR in the Medial Prefrontal Cortex in Female Syrian Hamsters. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674893. aggression results in the phosphorylation of erk1/2 in the nucleus accumbens and the dephosphorylation of mtor in the medial prefrontal cortex in female syrian hamsters. 2023-01-21 2023-08-14 Not clear
Johnathan M Borland, Desarae A Dempsey, Anna C Peyla, Megan A L Hall, Abigail L Kohut-Jackson, Paul G Mermelstein, Robert L Meise. Aggression Results in the Phosphorylation of ERK1/2 in the Nucleus Accumbens and the Dephosphorylation of mTOR in the Medial Prefrontal Cortex in Female Syrian Hamsters. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674893. we also report that aggressive interactions result in a transient decrease in the phosphorylation of mammalian target of rapamycin (mtor) in the medial prefrontal cortex, a major input structure to the nucleus accumbens. 2023-01-21 2023-08-14 Not clear
Alaa M Hammad, Asma'a Naser, Haneen Amawi, F Scott Hall, Amit K Tiwari, Bahaa Al-Tra. Effect of Amoxicillin/Clavulanic acid in attenuating Pregabalin-induced Condition Place Preference. Behavioural brain research. 2022-12-05. PMID:36470419. moreover, like other drugs of abuse, pregabalin also produced alterations in glutamate homeostasis, reducing the mrna expression of slc1a2 and slc7a11 in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc). 2022-12-05 2023-08-14 Not clear
Jameel N Hamdan, Jorge A Sierra-Fonseca, Rodolfo J Flores, Sigifredo Saucedo, Manuel Miranda-Arango, Laura E O'Dell, Kristin L Gosselin. Early-life adversity increases anxiety-like behavior and modifies synaptic protein expression in a region-specific manner. Frontiers in behavioral neuroscience. vol 16. 2022-11-07. PMID:36338879. the hippocampus (hipp), medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate putamen (cpu) were isolated from one subgroup of animals and subjected to western blot and protein quantitation for tyrosine hydroxylase (th), α-synuclein (alpha), nmda receptor (nmdar), dopamine receptor-1 (d1) and -2 (d2), dopamine transporter (dat), and postsynaptic density 95 (psd95). 2022-11-07 2023-08-14 rat
Martin Migliaro, Rodolfo Sánchez-Zavaleta, Eva Soto-Tinoco, Alejandra E Ruiz-Contreras, Mónica Méndez-Díaz, Andrea Herrera-Solís, Miguel Pérez de la Mora, Oscar E Prospéro-Garcí. Dominance status is associated with a variation in cannabinoid receptor 1 expression and amphetamine reward. Pharmacology, biochemistry, and behavior. 2022-10-21. PMID:36270348. in turn, the endocannabinoid system is an important modulator of drug reward in the nucleus accumbens and medial prefrontal cortex, however the connection with social dominance is yet to be established. 2022-10-21 2023-08-14 rat
William Parsons, Eliza Greiner, Laura Buczek, Jennifer Migliaccio, Erin Corbett, Amanda M K Madden, Gorica D Petrovic. Sex differences in activation of extra-hypothalamic forebrain areas during hedonic eating. Brain structure & function. 2022-10-18. PMID:36258044. the fos induction analysis identified sex differences in recruitment of specific areas of the medial prefrontal cortex, paraventricular nucleus of the thalamus (pvt), nucleus accumbens (acb), and central nucleus of the amygdala (cea), and similar patterns across sexes in the insular cortex. 2022-10-18 2023-08-14 rat
Ezio Carboni, Anna R Cart. BDNF Alterations in Brain Areas and the Neurocircuitry Involved in the Antidepressant Effects of Ketamine in Animal Models, Suggest the Existence of a Primary Circuit of Depression. Journal of integrative neuroscience. vol 21. issue 5. 2022-09-22. PMID:36137960. in this review we have examined the role of several brain areas: namely, the hippocampus, the medial prefrontal cortex (mpfc), the nucleus accumbens (nac), the lateral habenula (lhb), the amygdala and the bed nucleus of stria terminalis (bnst). 2022-09-22 2023-08-14 Not clear
Myung Ji Kwak, Wha Young Kim, Seung-Hyun Jung, Yeun-Jun Chung, Jeong-Hoon Ki. Differential transcriptome profile underlying risky choice in a rat gambling task. Journal of behavioral addictions. 2022-09-12. PMID:36094860. in the present study, we examined using next-generation sequencing (ngs) technique whether there are differences in gene expression profiles in the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac) when rats make different choices toward risk in rgt. 2022-09-12 2023-08-14 rat