| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Deniz Önal, Hilal Korkmaz, Gizem Önal, Bilge Pehlivanoğl. Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response. Peptides. 2024-03-31. PMID:38555975. |
prefrontal cortex and hypothalamic oxytocin receptor (oxtr) expression levels were identified using western blot analysis. |
2024-03-31 |
2024-04-03 |
rat |
| Deniz Önal, Hilal Korkmaz, Gizem Önal, Bilge Pehlivanoğl. Body Weight Modulates the Impact of Oxytocin on Chronic Cold-Immobilization Stress Response. Peptides. 2024-03-31. PMID:38555975. |
while oxtr expression levels in the prefrontal cortex did not vary according to the body weight and oxytocin application, oxtr levels in the hypothalamus were higher in the hfd- and/or oxytocin-treated animals. |
2024-03-31 |
2024-04-03 |
rat |
| Ekaterina Delikishkina, Shira Cohen-Zimerman, Zachary R Kachian, Frank Krueger, Barry Gordon, Jordan Grafma. Understanding altruistic behavior: The joint role of prefrontal damage and OXTR genotype. Neuropsychologia. 2023-09-23. PMID:37741549. |
yet the existing reports are contradictory and suggest that the top-down control exercised by the prefrontal cortex may promote both altruistic and self-interested behaviors and, thus, could obscure one's natural proclivity towards altruism encoded by oxtr. |
2023-09-23 |
2023-10-07 |
human |
| Cassandre Morel, Ines Martinez Sanchez, Yamina Cherifi, Nicolas Chartrel, Rochellys Diaz Heijt. Perturbation of maternal gut microbiota in mice during a critical perinatal window influences early neurobehavioral outcomes in offspring. Neuropharmacology. 2023-03-04. PMID:36870672. |
this behavioral phenotype of exposed juvenile males was associated with reduced gene expression of the oxytocin receptor (oxtr) and several tight-junction proteins in the prefrontal cortex, a key region involved in the regulation of social and emotional behavior, as well as a mild inflammatory response in the colon. |
2023-03-04 |
2023-08-14 |
mouse |
| Fabiana Festucci, Eugenia Annunzi, Martina Pepe, Giuseppe Curcio, Claudio D'Addario, Walter Adrian. Dopamine-transporter heterozygous rats carrying maternal wild-type allele are more vulnerable to the development of compulsive behavior. Synapse (New York, N.Y.). 2022-06-30. PMID:35772468. |
regarding the prefrontal cortex (pfc), d2r correlates with y-maze "perseverance" in addition to bdnf; considering the amygdala (amy), both d3r and oxtr correlate with sip "licks". |
2022-06-30 |
2023-08-14 |
human |
| Fabiana Festucci, Eugenia Annunzi, Martina Pepe, Giuseppe Curcio, Claudio D'Addario, Walter Adrian. Dopamine-transporter heterozygous rats carrying maternal wild-type allele are more vulnerable to the development of compulsive behavior. Synapse (New York, N.Y.). 2022-06-30. PMID:35772468. |
indeed, compulsivity may be linked to d2r and bdnf in pfc, while extreme anxiety in mat-het rats may be associated with d3r and oxtr in the amygdala. |
2022-06-30 |
2023-08-14 |
human |
| Lauren E Granata, Alissa Valentine, Jason L Hirsch, Heather C Brenhous. Infant ultrasonic vocalizations predict adolescent social behavior in rats: Effects of early life adversity. Developmental psychobiology. vol 64. issue 3. 2022-03-21. PMID:35312059. |
adolescent oxytocin receptor (oxtr) and arginine-vasopressin receptor 1a mrna were measured in the pfc. |
2022-03-21 |
2023-08-13 |
rat |
| Leanna M Hernandez, Katherine E Lawrence, N Tanya Padgaonkar, Marisa Inada, Jackson N Hoekstra, Jennifer K Lowe, Jeffrey Eilbott, Allison Jack, Elizabeth Aylward, Nadine Gaab, John D Van Horn, Raphael A Bernier, James C McPartland, Sara J Webb, Kevin A Pelphrey, Shulamite A Green, Daniel H Geschwind, Susan Y Bookheimer, Mirella Daprett. Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32127526. |
this increased connectivity between nacc and prefrontal cortex mirrored the relationship between genetic risk and brain connectivity observed in neurotypical males showing that, under increased oxtr genetic risk load, females with asd and neurotypical males displayed increased connectivity between reward-related brain regions and prefrontal cortex. |
2021-06-18 |
2023-08-13 |
Not clear |
| Kengo Horie, Kiyoshi Inoue, Katsuhiko Nishimori, Larry J Youn. Investigation of Oxtr-expressing Neurons Projecting to Nucleus Accumbens using Oxtr-ires-Cre Knock-in prairie Voles (Microtus ochrogaster). Neuroscience. vol 448. 2021-05-14. PMID:33092784. |
while oxtr in a few regions, such as the nucleus accumbnes (nacc), prefrontal cortex (pfc) and anterior cingulate cortex (acc), have been implicated in regulating these behaviors, the extent to which other oxt sensitive areas modulate social behaviors has not been investigated. |
2021-05-14 |
2023-08-13 |
mouse |
| Fariba Khodagholi, Ali Maleki, Fereshteh Motamedi, Maryam Alsadat Mousavi, Shahrbanoo Rafiei, Mehdi Moslem. Oxytocin Prevents the Development of 3-NP-Induced Anxiety and Depression in Male and Female Rats: Possible Interaction of OXTR and mGluR2. Cellular and molecular neurobiology. 2020-11-17. PMID:33201416. |
anxiety- and depression-like behaviors as well as the levels of oxytocin receptor (oxtr), metabotropic glutamate receptor (mglur) 2, mglur5, and glutathione (gsh) were measured in striatum, hippocampus, prefrontal cortex, and amygdala. |
2020-11-17 |
2023-08-13 |
rat |
| Virginia Meneghini Lazzari, Josi Maria Zimmermann-Peruzatto, Grasiela Agnes, Roberta Oriques Becker, Ana Carolina de Moura, Silvana Almeida, Renata Padilha Guedes, Marcia Giovenard. Hippocampal gene expression patterns in oxytocin male knockout mice are related to impaired social interaction. Behavioural brain research. vol 364. 2020-02-13. PMID:29102591. |
in this study, we evaluated the expression levels of the ot receptor (oxtr), avp receptors 1a and 1b (avpr1a; avpr1b), dopamine receptor 2 (drd2), and the estrogen receptors alpha and beta (esr1; esr2) genes in the hippocampus (hpc), olfactory bulb (ob), hypothalamus (hpt) and prefrontal cortex (pfc). |
2020-02-13 |
2023-08-13 |
mouse |
| Marta Maria Nowacka-Chmielewska, Daniela Kasprowska-Liśkiewicz, Jarosław Jerzy Barski, Ewa Obuchowicz, Andrzej Małeck. The behavioral and molecular evaluation of effects of social instability stress as a model of stress-related disorders in adult female rats. Stress (Amsterdam, Netherlands). vol 20. issue 6. 2018-06-15. PMID:28911267. |
hence, expression of pomc (pro-opiomelanocortin), avpr1a (arginine vasopressin receptor), and oxtr (oxytocin receptor) significantly increased in the amygdala following csis, while in pfc and/or hypothalamus, pomc, avpr1a, avpr1b, oxtr, and erβ (estrogen receptor beta) expression decreased. |
2018-06-15 |
2023-08-13 |
rat |
| Shota Nishitani, Kazuya Ikematsu, Tsunehiko Takamura, Sumihisa Honda, Koh-Ichiro Yoshiura, Kazuyuki Shinohar. Genetic variants in oxytocin receptor and arginine-vasopressin receptor 1A are associated with the neural correlates of maternal and paternal affection towards their child. Hormones and behavior. vol 87. 2017-09-07. PMID:27743766. |
to study this, we investigated the association between neural activation of the anterior prefrontal cortex (apfc) in mothers and fathers in response to their child smiling video stimuli to induce the positive affect related to attachment with their child, and genetic variants of ot receptor (oxtr) and avp receptor 1a (avpr1a). |
2017-09-07 |
2023-08-13 |
human |
| Brian W Haas, Ian W Anderson, Jessica M Smit. Navigating the complex path between the oxytocin receptor gene (OXTR) and cooperation: an endophenotype approach. Frontiers in human neuroscience. vol 7. 2014-06-24. PMID:24348360. |
however, it is currently unknown how the oxtr gene may be linked to the functional anatomy of other relevant brain regions that include the fusiform gyrus (fg), superior temporal sulcus (sts), ventromedial prefrontal cortex (vmpfc), temporoparietal junction (tpj) and nucleus accumbens (nacc). |
2014-06-24 |
2023-08-12 |
human |
| Sau-Yeen Loke, Kazuhiro Tanaka, Wei-Yi On. Comprehensive gene expression analyses of the rat prefrontal cortex after oxysterol treatment. Journal of neurochemistry. vol 124. issue 6. 2013-04-29. PMID:23294445. |
immunohistochemical analysis showed localization of oxtr in neurons of the pfc. |
2013-04-29 |
2023-08-12 |
rat |
| Carina Anicet Ruthschilling, Gabriela Albiero, Virgínia Meneghini Lazzari, Roberta Oriques Becker, Ana Carolina de Moura, Aldo Bolten Lucion, Silvana Almeida, Ana Beatriz Gorini da Veiga, Márcia Giovenard. Analysis of transcriptional levels of the oxytocin receptor in different areas of the central nervous system and behaviors in high and low licking rats. Behavioural brain research. vol 228. issue 1. 2012-05-24. PMID:22178314. |
the present study examined the responses of hl and ll rats in several behavioral tests and analyzes the transcription of the oxytocin receptor (oxtr) in the olfactory bulb (ob), the prefrontal cortex (fpc), the hippocampus (hp) and the striatum (st) in different patterns of licking behavior. |
2012-05-24 |
2023-08-12 |
rat |