| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mar\\xc3\\xada Vargas-Soria, M\\xc3\\xb3nica Garc\\xc3\\xada-Alloza, Miriam Corraliza-G\\xc3\\xb3me. Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies. Journal of neuroinflammation vol 20 issue 1 2023 36869375 |
based on the title and abstracts, 830 papers were screened from which 250 primary research papers met the eligibility criteria (original research articles with patients or with a strict diabetes model without comorbidities, that included direct data about microglia in the brain or retina), and 17 additional research papers were included through forward and backward citations, resulting in a total of 267 primary research articles included in the scoping systematic review. |
2023-03-03 |
2023-03-06 |
Not clear |
| Nan Su, Uwe Hansen, Tanja Plagemann, Karin G\\xc3\\xa4her, M Dominik Leclaire, Jeannette K\\xc3\\xb6nig, Annika H\\xc3\\xb6hn, Tilman Grune, Constantin E Uhlig, Nicole Eter, Peter Heiduschk. Sub-Retinal Injection of Human Lipofuscin in the Mouse - A Model of \"Dry\" Age-Related Macular Degeneration? Aging and disease vol 14 issue 1 2023 36818572 |
in an attemt to simulate aged retina and to study response of retinal microglia and rpe cells to lf, we injected a suspension of lf into the subretinal space of adult mice. |
2023-02-23 |
2023-03-06 |
mouse |
| Nan Su, Uwe Hansen, Tanja Plagemann, Karin G\\xc3\\xa4her, M Dominik Leclaire, Jeannette K\\xc3\\xb6nig, Annika H\\xc3\\xb6hn, Tilman Grune, Constantin E Uhlig, Nicole Eter, Peter Heiduschk. Sub-Retinal Injection of Human Lipofuscin in the Mouse - A Model of \"Dry\" Age-Related Macular Degeneration? Aging and disease vol 14 issue 1 2023 36818570 |
in an attemt to simulate aged retina and to study response of retinal microglia and rpe cells to lf, we injected a suspension of lf into the subretinal space of adult mice. |
2023-02-23 |
2023-03-06 |
mouse |
| Ioanna Tsioti, Beatrice L Steiner, Pascal Escher, Martin S Zinkernagel, Peter M Benz, Despina Kokon. Endothelial Toll-like receptor 4 is required for microglia activation in the murine retina after systemic lipopolysaccharide exposure. Journal of neuroinflammation vol 20 issue 1 2023 36739425 |
endothelial toll-like receptor 4 is required for microglia activation in the murine retina after systemic lipopolysaccharide exposure. |
2023-02-04 |
2023-03-06 |
mouse |
| Ioanna Tsioti, Beatrice L Steiner, Pascal Escher, Martin S Zinkernagel, Peter M Benz, Despina Kokon. Endothelial Toll-like receptor 4 is required for microglia activation in the murine retina after systemic lipopolysaccharide exposure. Journal of neuroinflammation vol 20 issue 1 2023 36739425 |
clustering of microglia around the vasculature has been reported in the retina and the brain after systemic administration of lipopolysaccharides (lps) in mice. |
2023-02-04 |
2023-03-06 |
mouse |
| Ioanna Tsioti, Beatrice L Steiner, Pascal Escher, Martin S Zinkernagel, Peter M Benz, Despina Kokon. Endothelial Toll-like receptor 4 is required for microglia activation in the murine retina after systemic lipopolysaccharide exposure. Journal of neuroinflammation vol 20 issue 1 2023 36739425 |
the purpose of this study was to investigate the effect of systemic lps in the pigmented mouse retina and the involvement of endothelial tlr4 in lps-induced retinal microglia activation. |
2023-02-04 |
2023-03-06 |
mouse |
| Yanying Miao, Guo-Li Zhao, Shuo Cheng, Zhongfeng Wang, Xiong-Li Yan. Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma. Progress in retinal and eye research vol 93 issue 2023 36736070 |
elevated iop activates microglia, and following morphological and functional changes, these cells, as resident immune cells in the retina, show adaptive immune responses, including an enhanced release of pro-inflammatory factors (tumor neurosis factor-\xce\xb1, interleukins, etc.). |
2023-02-03 |
2023-03-06 |
Not clear |
| Valeria Chichagova, Maria Georgiou, Madeleine Carter, Birthe Dorgau, Gerrit Hilgen, Joseph Collin, Rachel Queen, Git Chung, Jila Ajeian, Marina Moya-Molina, Stefan Kustermann, Francois Pognan, Philip Hewitt, Michael Schmitt, Evelyne Sernagor, Lyle Armstrong, Majlinda Lak. Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids. Journal of cellular and molecular medicine vol issue 2023 36644817 |
microglia are the primary resident immune cells in the retina. |
2023-01-16 |
2023-01-30 |
human |
| Megan Goyal, Andrea S Bordt, Jay Neitz, David W Marsha. Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. Scientific reports vol 13 issue 1 2023 36635325 |
trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. |
2023-01-12 |
2023-01-30 |
mouse |
| Megan Goyal, Andrea S Bordt, Jay Neitz, David W Marsha. Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. Scientific reports vol 13 issue 1 2023 36635325 |
here we report that microglia in the adult macaque retina also engulf pieces of neurons and glial cells, but not at sites of synapses. |
2023-01-12 |
2023-01-30 |
mouse |
| Megan Goyal, Andrea S Bordt, Jay Neitz, David W Marsha. Trogocytosis of neurons and glial cells by microglia in a healthy adult macaque retina. Scientific reports vol 13 issue 1 2023 36635325 |
we analyzed microglia in a volume of serial, ultrathin sections of central macaque retina in which many neurons that ramify in the inner plexiform layer (ipl) had been reconstructed previously. |
2023-01-12 |
2023-01-30 |
mouse |
| Ming-Hui Sun, Kuan-Jen Chen, Chi-Chin Sun, Rong-Kung Tsa. Protective Effect of Pioglitazone on Retinal Ganglion Cells in an Experimental Mouse Model of Ischemic Optic Neuropathy. International journal of molecular sciences vol 24 issue 1 2023 36613856 |
furthermore, microglial cell infiltration in the retina (group 1: 2.0 \xc2\xb1 2.6 cells/field; group 2: 15.6 \xc2\xb1 3.5 cells/field; and group 3: 14.8 \xc2\xb1 7.5 cells/field) and retinal thinning (group 1: 6.7 \xc2\xb1 5.7 \xce\xbcm; group 2: 12.8 \xc2\xb1 6.1 \xce\xbcm; and group 3: 15.8 \xc2\xb1 5.8 \xce\xbcm) were also lower in group 1 than in the other two groups. |
2023-01-08 |
2023-01-30 |
mouse |
| Kjell Johansson, Camilla Mohli. Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International journal of molecular sciences vol 24 issue 1 2023 36614320 |
microglia in cultured porcine retina: qualitative immunohistochemical analyses of reactive microglia in the outer retina. |
2023-01-08 |
2023-01-30 |
Not clear |
| Kjell Johansson, Camilla Mohli. Microglia in Cultured Porcine Retina: Qualitative Immunohistochemical Analyses of Reactive Microglia in the Outer Retina. International journal of molecular sciences vol 24 issue 1 2023 36614320 |
in this immunohistochemical study, we have begun to analyze the transition of subsets of reactive microglia which are known to localize close to the outer plexiform layer (opl) in degenerating in vivo and in vitro retina. |
2023-01-08 |
2023-01-30 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology vol 13 issue 2022 36524119 |
more than meets the eye: the role of microglia in healthy and diseased retina. |
2022-12-16 |
2023-01-30 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology vol 13 issue 2022 36524119 |
while most knowledge about microglia comes from brain studies, some mechanisms have been confirmed for microglia cells in the retina, the light-sensing compartment of the eye responsible for initial processing of visual information. |
2022-12-16 |
2023-01-30 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology vol 13 issue 2022 36524119 |
however, several key pieces of this puzzle are still unaccounted for, as the characterization of retinal microglia has long been hindered by the reduced population size within the retina as well as the previous lack of technologies enabling single-cell analyses. |
2022-12-16 |
2023-01-30 |
Not clear |
| Elisa Murenu, Maximilian-Joachim Gerhardt, Martin Biel, Stylianos Michalaki. More than meets the eye: The role of microglia in healthy and diseased retina. Frontiers in immunology vol 13 issue 2022 36524119 |
thus, studying the roles and signatures adopted specifically by microglia in the retina has become increasingly important. |
2022-12-16 |
2023-01-30 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, Jos\\xc3\\xa9 L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation vol 19 issue 1 2022 36517889 |
models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. |
2022-12-14 |
2023-01-30 |
Not clear |
| Kaira A Church, Derek Rodriguez, Difernando Vanegas, Irene L Gutierrez, Sandra M Cardona, Jos\\xc3\\xa9 L M Madrigal, Tejbeer Kaur, Astrid E Cardon. Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina. Journal of neuroinflammation vol 19 issue 1 2022 36517889 |
microglia, the resident phagocytes of the retina, are believed to influence the development of retinopathy, but their exact contributions to vascular integrity and neuronal loss are unknown. |
2022-12-14 |
2023-01-30 |
Not clear |