| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehdi Zargani, Rodrigo Ramirez-Campillo, Ehsan Arabzade. Swimming and L-arginine loaded chitosan nanoparticles ameliorates aging-induced neuron atrophy, autophagy marker LC3, GABA and BDNF-TrkB pathway in the spinal cord of rats. Pflugers Archiv : European journal of physiology vol issue 2023 36869900 |
the old sw\xe2\x80\x89+\xe2\x80\x89la-cnps group increased (improved) spinal cord gaba (p\xe2\x80\x89=\xe2\x80\x890.0187), bdnf (p\xe2\x80\x89=\xe2\x80\x890.0003), trkb (p\xe2\x80\x89<\xe2\x80\x890.0001) gene expression, decreased autophagy marker lc3 protein (p\xe2\x80\x89<\xe2\x80\x890.0001), nerve atrophy and jumping/licking latency (p\xe2\x80\x89<\xe2\x80\x890.0001), improved sciatic functional index score and total oxidant status/total antioxidant capacity compared to the old group (p\xe2\x80\x89<\xe2\x80\x890.0001). |
2023-03-04 |
2023-03-06 |
rat |
| Takahiro Shibata, Syoichi Tashiro, Shinsuke Shibata, Munehisa Shinozaki, Tomoko Shindo, Shogo Hashimoto, Momotaro Kawai, Takahiro Kitagawa, Kentaro Ago, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano, Narihito Nagosh. Rehabilitative Training Enhances Therapeutic Effect of Human-iPSC-Derived Neural Stem/Progenitor Cells Transplantation in Chronic Spinal Cord Injury. Stem cells translational medicine vol issue 2023 36647673 |
the combination therapy was able to enhance the expressions of the bdnf and nt-3 proteins in the spinal cord tissue. |
2023-01-17 |
2023-01-30 |
Not clear |
| Sarah Thomas Broome, Alessandro Castorin. Systemic Rotenone Administration Causes Extra-Nigral Alterations in C57BL/6 Mice. Biomedicines vol 10 issue 12 2022 36551930 |
molecular analyses showed reductions of both th and dat expression in the midbrain, striatum and spinal cord, accompanied by altered expression of dopamine receptors and brain-derived neurotrophic factor (bdnf). |
2022-12-23 |
2023-01-30 |
mouse |
| Akihito Sotome, Ken Kadoya, Yuki Suzuki, Norimasa Iwasak. Spinal Canal and Spinal Cord in Rat Continue to Grow Even after Sexual Maturation: Anatomical Study and Molecular Proposition. International journal of molecular sciences vol 23 issue 24 2022 36555713 |
the present study, in conjunction with recent evidence, proposes the hypothetical model that the growth of rat spinal cord after the postnatal period is mediated at least in part by differentiation of neural progenitor cells and that their differentiation potency is maintained by vegfa, fgf2, and bdnf. |
2022-12-23 |
2023-01-30 |
rat |
| Keegan Nhan, Kendra R Todd, Garett S Jackson, Jan W Van der Scheer, Gabriel U Dix, Kathleen A Martin Ginis, Jonathan P Little, Jeremy J Wals. Acute submaximal exercise does not impact aspects of cognition and BDNF in people with spinal cord injury: A pilot study. Frontiers in rehabilitation sciences vol 3 issue 2022 36451805 |
acute submaximal exercise does not impact aspects of cognition and bdnf in people with spinal cord injury: a pilot study. |
2022-12-01 |
2023-01-30 |
Not clear |
| Keegan Nhan, Kendra R Todd, Garett S Jackson, Jan W Van der Scheer, Gabriel U Dix, Kathleen A Martin Ginis, Jonathan P Little, Jeremy J Wals. Acute submaximal exercise does not impact aspects of cognition and BDNF in people with spinal cord injury: A pilot study. Frontiers in rehabilitation sciences vol 3 issue 2022 36451805 |
to investigate the effect of acute submaximal exercise, based on the spinal cord injury (sci) exercise guidelines, on cognition and brain-derived neurotrophic factor (bdnf) in people with sci. |
2022-12-01 |
2023-01-30 |
Not clear |
| Anna G\\xc5\\x82owacka, Benjun Ji, Andrzej Antoni Szczepankiewicz, Ma\\xc5\\x82gorzata Skup, Olga Gajewska-Wo\\xc5\\xbania. BDNF Spinal Overexpression after Spinal Cord Injury Partially Protects Soleus Neuromuscular Junction from Disintegration, Increasing VAChT and AChE Transcripts in Soleus but Not Tibialis Anterior Motoneurons. Biomedicines vol 10 issue 11 2022 36359371 |
bdnf spinal overexpression after spinal cord injury partially protects soleus neuromuscular junction from disintegration, increasing vacht and ache transcripts in soleus but not tibialis anterior motoneurons. |
2022-11-11 |
2023-01-30 |
rat |
| Yuanyuan Li, Amanda Tran, Lori Graham, John Brock, Mark H Tuszynski, Paul L. BDNF guides neural stem cell-derived axons to ventral interneurons and motor neurons after spinal cord injury. Experimental neurology vol issue 2022 36309123 |
bdnf guides neural stem cell-derived axons to ventral interneurons and motor neurons after spinal cord injury. |
2022-10-29 |
2023-01-30 |
rat |
| Jagjit Singh, Surabhi Thapliyal, Ashish Kumar, Pranoy Paul, Nitesh Kumar, Manisha Bisht, Manisha Naithani, Shalinee Rao, Shailendra S Hand. Dimethyl Fumarate Ameliorates Paclitaxel-Induced Neuropathic Pain in Rats. Cureus vol 14 issue 9 2022 36225395 |
the levels of p38 mitogen-activated protein kinase (mapk) and brain-derived neurotrophic factor (bdnf) were quantified in the dorsal horn of the spinal cord. |
2022-10-13 |
2023-01-30 |
rat |
| Karmarcha K Martin, Donald J Noble, Shangrila Parvin, Kyeongran Jang, Sandra M Garrawa. Pharmacogenetic inhibition of TrkB signaling in adult mice attenuates mechanical hypersensitivity and improves locomotor function after spinal cord injury. Frontiers in cellular neuroscience vol 16 issue 2022 36226073 |
the exact involvement of bdnf and trkb in neuropathic pain states after spinal cord injury (sci) remains unresolved. |
2022-10-13 |
2023-01-30 |
mouse |
| Xiaojing Lin, Tingbao Zhao, Guiping Mei, Ruoxu Liu, Chenyi Li, Xiaowen Wang, Zixuan Qu, Shide Lin, M J Walker, Xueqing Yi, Peng Zhang, Kuang-Wen Tseng, Xiao-Ming Xu, Cheng-Hsien Lin, Gang Su. 7,8-Dihydroxyflavone accelerates recovery of Brown-Sequard syndrome in adult female rats with spinal cord lateral hemisection. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol 153 issue 2022 36076480 |
since local bdnf delivery to the injured spinal cord enhanced diaphragmatic respiratory function, we aimed to ascertain whether dhf might have similar beneficial effects after brown-sequard syndrome in a rat model of spinal cord lateral hemisection (hx) at the 9th thoracic (t9) vertebral level. |
2022-09-09 |
2023-01-30 |
rat |
| Liqiong He, Wei Xu, Chengliang Zhang, Zhuofeng Ding, Qulian Guo, Wangyuan Zou, Jian Wan. Dysregulation of Vesicular Glutamate Transporter VGluT2 Frontiers in pharmacology vol 13 issue 2022 35559256 |
in addition, we found the expression of bdnf is correlated with vglut2 expression in the spinal cord after chronic morphine administration. |
2022-05-13 |
2023-01-27 |
mouse |
| Anke Vermehren-Schmaedick, Mark J Olah, Damien Ramunno-Johnson, Keith A Lidke, Michael S Cohen, Tania Q V. Molecular-Scale Dynamics of Long Range Retrograde Brain-Derived Neurotrophic Factor Transport Shaped by Cellular Spatial Context. Frontiers in neuroscience vol 16 issue 2022 35431786 |
brain-derived neurotrophic factor (bdnf) is an abundant nt that modulates key brain and spinal cord functions, and defects in bdnf trafficking are associated with neuronal death, neurodegenerative diseases and in nerve injury. |
2022-04-18 |
2023-01-27 |
Not clear |
| E K Karsuntseva, G A Fursa, A O Sosnovtseva, A D Voronova, A V Chadin, A S Semkina, O V Stepanova, V P Chekhoni. Application of a New Gene-Cell Construct Based on the Olfactory Mucosa Escheating Cells Transduced with an Adenoviral Vector Encoding Mature BDNF in the Therapy of Spinal Cord Cysts. Bulletin of experimental biology and medicine vol issue 2022 35352253 |
application of a new gene-cell construct based on the olfactory mucosa escheating cells transduced with an adenoviral vector encoding mature bdnf in the therapy of spinal cord cysts. |
2022-03-30 |
2023-01-27 |
rat |
| Hongbin Luo, Xuemin Chen, Peifeng Zhuang, Songye Wu, Jie Wei, Weihong X. Cotransplantation with RADA16-PRG-Self-Assembled Nanopeptide Scaffolds, Bone Mesenchymal Stem Cells and Brain-Derived Neurotrophic Factor-Adeno-Associated Virus Promote Functional Repair After Acute Spinal Cord Injury in Rats. Journal of biomedical nanotechnology vol 18 issue 1 2022 35180916 |
the results showed that cotransplantation of rada16-prg-sapns, bmscs, and bdnf-avv promoted the spinal cord's motor and sensory function of sci rats; increased levels of bmscs, inhabited glial cells proliferation, and promoted neurons proliferations in the injured area; and increased nf, bdnf, and nse levels and decreased its gfap in the injured area. |
2022-02-19 |
2023-01-27 |
rat |
| Shuo Zhao, Fengyu Wang, Li Wang, Yali Xu, Li Lv, Wenxu Duan, Runze Bai, Zhao Meng, Xinzhong Sha. Involvement of the BDNF-TrkB-KCC2 pathway in neuropathic pain after brachial plexus avulsion. Brain and behavior vol issue 2022 35106976 |
brachial plexus avulsion significantly increased brain-derived neurotrophic factor (bdnf) release in the spinal cord. |
2022-02-02 |
2023-01-27 |
Not clear |
| Wenlin Hao, Qinghua Luo, Michael D Menger, Klaus Fassbender, Yang Li. Treatment With CD52 Antibody Protects Neurons in Experimental Autoimmune Encephalomyelitis Mice During the Recovering Phase. Frontiers in immunology vol 12 issue 2022 34975892 |
neuronal deficiency of bdnf attenuated the effect of anti-cd52 treatment on reducing eae scores and inflammatory infiltration but did not affect anti-cd52 treatment-induced improvement of myelin coverage in the spinal cord. |
2022-01-03 |
2023-01-26 |
mouse |
| Hui Yang, Lin Wang, Xiao Chu, Xiaojuan Shi, Xinhe Li, Tieshan L. BoNT/A alleviates neuropathic pain in osteoarthritis by down-regulating the expression of P2X4R in spinal microglia. Toxicon : official journal of the International Society on Toxinology vol issue 2021 34954133 |
western blot analysis was used to examine the expression of p2x4r and bdnf proteins in the spinal cord. |
2021-12-26 |
2023-01-26 |
rat |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Hongyun Huang, Preeti K Menon, Seaab Sahib, Z Ryan Tian, Jos\\xc3\\xa9 Vicente Lafuente, Anca D Buzoianu, Rudy J Castellani, Ala Nozari, Lars Wiklund, Hari Shanker Sharm. Topical application of CNTF, GDNF and BDNF in combination attenuates blood-spinal cord barrier permeability, edema formation, hemeoxygenase-2 upregulation, and cord pathology. Progress in brain research vol 266 issue 2021 34689864 |
previously, topical application of bdnf and gdnf in combination over the injured spinal cord after 90min induced marked neuroprotection. |
2021-11-24 |
2023-01-26 |
Not clear |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Hongyun Huang, Preeti K Menon, Seaab Sahib, Z Ryan Tian, Jos\\xc3\\xa9 Vicente Lafuente, Anca D Buzoianu, Rudy J Castellani, Ala Nozari, Lars Wiklund, Hari Shanker Sharm. Topical application of CNTF, GDNF and BDNF in combination attenuates blood-spinal cord barrier permeability, edema formation, hemeoxygenase-2 upregulation, and cord pathology. Progress in brain research vol 266 issue 2021 34689864 |
topical application of cntf with bdnf and gdnf in combination (10ng each) after 90 and 120min over the injured spinal cord significantly attenuated the bscb breakdown, edema formation, cell injury and overexpression of ho-2. |
2021-11-24 |
2023-01-26 |
Not clear |