All Relations between spinal cord and bdnf

Publication Sentence Publish Date Extraction Date Species
Chihiro Tanji, Masayuki Hashimoto, Takeo Furuya, Junya Saito, Takuya Miyamoto, Masao Kod. Sigma 1 receptor agonist cutamesine promotes plasticity of serotonergic boutons in lumbar enlargement in spinal cord injured rats. Neuroscience letters. vol 759. 2021-08-06. PMID:34023415. in sci rats, cutamesine treatment (3.0 mg/kg/day) significantly increased the fluorescence intensity of neuronal bdnf and serotonin boutons in the injured spinal cord compared to saline. 2021-08-06 2023-08-13 rat
Pei Wang, Ruian Yin, Shuangyan Wang, Ting Zhou, Yongjie Zhang, Ming Xiao, Hongxing Wang, Guangxu X. Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) and Treadmill Training on Recovery of Motor Function in a Rat Model of Partial Spinal Cord Injury. Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-08-04. PMID:34304239. outcomes studied were basso, beattie, and bresnahan locomotor scale scores, grid walking test, and biochemical analysis of the brain-derived neurotrophic factor (bdnf), synapsin i (syn), and postsynaptic density protein-95 (psd-95) in the motor cortex and spinal cord. 2021-08-04 2023-08-13 rat
Pei Wang, Ruian Yin, Shuangyan Wang, Ting Zhou, Yongjie Zhang, Ming Xiao, Hongxing Wang, Guangxu X. Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) and Treadmill Training on Recovery of Motor Function in a Rat Model of Partial Spinal Cord Injury. Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-08-04. PMID:34304239. the rtms/tt significantly increased the expressions of bdnf, syn, and psd-95 compared with the s-rtms/non-tt, both in the motor cortex (p<0.01, p<0.01, p<0.001, respectively) and spinal cord (p<0.001, p<0.01, p<0.05, respectively). 2021-08-04 2023-08-13 rat
Da-Jeong Chang, Hwi-Young Cho, Seyoung Hwang, Nayeon Lee, Chunggab Choi, Hyunseung Lee, Kwan Soo Hong, Seung-Hun Oh, Hyun Sook Kim, Dong Ah Shin, Young Wook Yoon, Jihwan Son. Therapeutic Effect of BDNF-Overexpressing Human Neural Stem Cells (F3.BDNF) in a Contusion Model of Spinal Cord Injury in Rats. International journal of molecular sciences. vol 22. issue 13. 2021-08-02. PMID:34203489. in this study, we applied genetically modified human neural stem cells overexpressing bdnf (brain-derived neurotrophic factor) (f3.bdnf) to determine whether they can promote functional recovery in the spinal cord injury (sci) model in rats. 2021-08-02 2023-08-13 human
Francesca Marchionne, Alexander J Krupka, George M Smith, Michel A Lema. Intrathecal Delivery of BDNF Into the Lumbar Cistern Re-Engages Locomotor Stepping After Spinal Cord Injury. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 28. issue 11. 2021-06-24. PMID:32986558. intrathecal delivery of bdnf into the lumbar cistern re-engages locomotor stepping after spinal cord injury. 2021-06-24 2023-08-13 Not clear
Xinxin Zhou, Lei Tao, Mengru Zhao, Shengjun Wu, Enoch Obeng, Dan Wang, Wenping Zhan. Wnt/ Molecular pain. vol 16. 2021-06-03. PMID:32354292. we found that wnt3a and β-catenin expression levels increased in the spinal cord of hnp mice, consequently regulating the expression of bdnf and affecting hypersensitivity. 2021-06-03 2023-08-13 mouse
Sining Feng, Shuai Wang, Shi Sun, Hao Su, Lixin Zhan. Effects of combination treatment with transcranial magnetic stimulation and bone marrow mesenchymal stem cell transplantation or Raf inhibition on spinal cord injury in rats. Molecular medicine reports. vol 23. issue 4. 2021-05-17. PMID:33649786. notably, combination therapy further alleviated sci‑induced spinal cord lesions and neuronal apoptosis, increased gap‑43, ngf and bdnf expression levels, downregulated gfap expression levels and inhibited activation of the raf/mek/erk signaling pathway in sci model rats compared with the corresponding monotherapy groups. 2021-05-17 2023-08-13 rat
Camila Lino de Oliveira, Liciane Fernandes Medeiros, Vanessa Silva de Souza, Bettega Costa Lopes, Fabricio Finamor de Oliveira, Luana Xavier Marques, Iraci Lucena da Silva Torres, Andressa de Souz. LOW-DOSE NALTREXONE REVERSES FACIAL MECHANICAL ALLODYNIA IN A RAT MODEL OF TRIGEMINAL NEURALGIA. Neuroscience letters. vol 736. 2021-05-13. PMID:32673692. spinal cord levels of bdnf and il-10 were modulated by low-dose naltrexone. 2021-05-13 2023-08-13 rat
Claire Richard, Claude Bendavid, Juliette Hascoet, Quentin Alimi, Zine-Eddine Khene, Jacques Kerdraon, Caroline Voiry, Charlène Brochard, Guillaume Bouguen, Laurent Siproudhis, Andrea Manunta, Xavier Gamé, Benoit Peyronne. Urinary biomarkers profiles in patients with neurogenic detrusor overactivity according to their neurological condition. World journal of urology. vol 38. issue 9. 2021-05-06. PMID:31741027. the aim of this study was to investigate the disease-specific urinary levels variations of neurotrophins (ngf, bdnf), mediators of inflammation (tgfβ-1, pge-2) and markers of extracellular matrix alterations (timp-2) in patients with multiple sclerosis (ms) spinal cord injury (sci), or spina bifida (sb), and neurogenic detrusor overactivity (ndo). 2021-05-06 2023-08-13 Not clear
Wei-Wei Deng, Guang-Yan Wu, Ling-Xia Min, Zhou Feng, Hui Chen, Ming-Liang Tan, Jian-Feng Sui, Hong-Liang Liu, Jing-Ming Ho. Optogenetic Neuronal Stimulation Promotes Functional Recovery After Spinal Cord Injury. Frontiers in neuroscience. vol 15. 2021-04-28. PMID:33897353. in addition, hematoxylin-eosin staining and nerve fiber staining at the injured site showed that accurate activation of the primary motor cortex could effectively promote tissue recovery and neurofilament growth (gap-43, nf) at the injured site of the spinal cord, while the content of some growth-related proteins (bdnf, ngf) at the injured site increased. 2021-04-28 2023-08-13 rat
Fei Huang, Taiying Chen, Jun Chang, Chi Zhang, Faxue Liao, Linwei Wu, Wenbin Wang, Zongsheng Yi. A conductive dual-network hydrogel composed of oxidized dextran and hyaluronic-hydrazide as BDNF delivery systems for potential spinal cord injury repair. International journal of biological macromolecules. vol 167. 2021-04-19. PMID:33278434. a conductive dual-network hydrogel composed of oxidized dextran and hyaluronic-hydrazide as bdnf delivery systems for potential spinal cord injury repair. 2021-04-19 2023-08-13 Not clear
Naoki Sada, Yuki Fujita, Nanano Mizuta, Masaki Ueno, Takahisa Furukawa, Toshihide Yamashit. Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury. Cell death & disease. vol 11. issue 8. 2021-04-13. PMID:32811822. after tbi, hdac2 expression was increased in the spinal cord after 35 days, whereas bdnf expression was decreased after 42 days. 2021-04-13 2023-08-13 mouse
Meysam Ghorbani, Parviz Shahabi, Pouran Karimi, Hamid Soltani-Zangbar, Mohammad Morshedi, Soheila Bani, Mohsen Jafarzadehgharehziaaddin, Behnaz Sadeghzadeh-Oskouei, Ali Ahmadalipou. Impacts of epidural electrical stimulation on Wnt signaling, FAAH, and BDNF following thoracic spinal cord injury in rat. Journal of cellular physiology. vol 235. issue 12. 2021-04-02. PMID:32488870. impacts of epidural electrical stimulation on wnt signaling, faah, and bdnf following thoracic spinal cord injury in rat. 2021-04-02 2023-08-13 rat
Kae Ikeda, Keita Hazama, Yoshitaro Itano, Mamoru Ouchida, Hideki Nakatsuk. Development of a novel analgesic for neuropathic pain targeting brain-derived neurotrophic factor. Biochemical and biophysical research communications. vol 531. issue 3. 2021-03-10. PMID:32800540. bdnf binds to a member of the tyrosine kinase receptor family, the trkb receptor, that is specific for bdnf and is the transmembrane receptor on the posterior horn of spinal cord. 2021-03-10 2023-08-13 rat
Meng Xue, Ya-Lan Sun, Yang-Yang Xia, Zhi-Hua Huang, Cheng Huang, Guo-Gang Xin. Electroacupuncture Modulates Spinal BDNF/TrκB Signaling Pathway and Ameliorates the Sensitization of Dorsal Horn WDR Neurons in Spared Nerve Injury Rats. International journal of molecular sciences. vol 21. issue 18. 2021-02-22. PMID:32906633. the results showed that 2 hz ea significantly down-regulated the levels of bdnf and trκb mrna and protein expression in the spinal cord of sni rats, along with ameliorating mechanical hypersensitivity. 2021-02-22 2023-08-13 rat
Tongxia Zhang, Chong Liu, Lingyi Ch. Suppression of miR-10a-5p in bone marrow mesenchymal stem cells enhances the therapeutic effect on spinal cord injury via BDNF. Neuroscience letters. vol 714. 2021-01-04. PMID:31626878. suppression of mir-10a-5p in bone marrow mesenchymal stem cells enhances the therapeutic effect on spinal cord injury via bdnf. 2021-01-04 2023-08-13 Not clear
Tongxia Zhang, Chong Liu, Lingyi Ch. Suppression of miR-10a-5p in bone marrow mesenchymal stem cells enhances the therapeutic effect on spinal cord injury via BDNF. Neuroscience letters. vol 714. 2021-01-04. PMID:31626878. this study aims to explore whether regulation of bdnf through micrornas (mirnas) in mscs may further enhance the therapeutic effect on spinal cord injury (sci). 2021-01-04 2023-08-13 Not clear
Michiharu Matsuda, Haruo Kanno, Takehiro Sugaya, Seiji Yamaya, Kenichiro Yahata, Kyoichi Handa, Tomohiko Shindo, Hiroaki Shimokawa, Hiroshi Ozawa, Eiji Ito. Low-energy extracorporeal shock wave therapy promotes BDNF expression and improves functional recovery after spinal cord injury in rats. Experimental neurology. vol 328. 2020-12-30. PMID:32087252. low-energy extracorporeal shock wave therapy promotes bdnf expression and improves functional recovery after spinal cord injury in rats. 2020-12-30 2023-08-13 human
Michiharu Matsuda, Haruo Kanno, Takehiro Sugaya, Seiji Yamaya, Kenichiro Yahata, Kyoichi Handa, Tomohiko Shindo, Hiroaki Shimokawa, Hiroshi Ozawa, Eiji Ito. Low-energy extracorporeal shock wave therapy promotes BDNF expression and improves functional recovery after spinal cord injury in rats. Experimental neurology. vol 328. 2020-12-30. PMID:32087252. the aim of the current study was to determine whether the application of low-energy eswt upregulates the expression of brain-derived neurotrophic factor (bdnf) and reduces neural tissue damage and functional impairment using a rat model of thoracic spinal cord contusion injury. 2020-12-30 2023-08-13 human
Michiharu Matsuda, Haruo Kanno, Takehiro Sugaya, Seiji Yamaya, Kenichiro Yahata, Kyoichi Handa, Tomohiko Shindo, Hiroaki Shimokawa, Hiroshi Ozawa, Eiji Ito. Low-energy extracorporeal shock wave therapy promotes BDNF expression and improves functional recovery after spinal cord injury in rats. Experimental neurology. vol 328. 2020-12-30. PMID:32087252. these findings indicate that low-energy eswt promotes bdnf expression at the lesion site and reduces the neural tissue damage and functional impairment following spinal cord injury. 2020-12-30 2023-08-13 human