| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aïda Padilla-Ferrer, Alex Carrete, Anne Simon, Delphine Meffre, Mehrnaz Jafarian-Tehran. A disintegrin and Metalloprotease 10 expression within the murine central nervous system. Brain research. 2024-03-28. PMID:38548249. |
we observed adam10 expression through the whole cns, with a strong expression in the hippocampus, in the hypothalamus and in the cerebral and piriform cortex in the brain, in the purkinje and in granular cell layers in the cerebellum and in the spinal cord to a lower extent. |
2024-03-28 |
2024-03-31 |
mouse |
| Yang Yang, Chao Yang, Yujie Shi, Chengyuan Tang, Hanyu Wang, Mengyuan Tan, Ruyi Xing, Chen Gao, Min Zhang, Yanhu Xi. Ciprofol alleviates remifentanil-induced hyperalgesia by regulating α2GABAARs, NR2B, and P-CaMKIIα levels in the spinal cord and hippocampus. The Journal of pharmacy and pharmacology. 2024-03-26. PMID:38530642. |
ciprofol alleviates remifentanil-induced hyperalgesia by regulating α2gabaars, nr2b, and p-camkiiα levels in the spinal cord and hippocampus. |
2024-03-26 |
2024-03-29 |
Not clear |
| Ying Ma, Yue Qiao, Xiang Ga. Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488549. |
potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. |
2024-03-15 |
2024-03-17 |
Not clear |
| Ying Ma, Yue Qiao, Xiang Ga. Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression. Neural regeneration research. vol 19. issue 10. 2024-03-15. PMID:38488549. |
one of possible factors underlying the depression is the reduction of adult hippocampal neurogenesis which may come from less physical activity, social isolation, chronic pain, and elevated neuroinflammation after spinal cord injury. |
2024-03-15 |
2024-03-17 |
Not clear |
| Erratum: Liu et al., "TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury". The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-03-04. PMID:38438261. |
erratum: liu et al., "tnf-α differentially regulates synaptic plasticity in the hippocampus and spinal cord by microglia-dependent mechanisms after peripheral nerve injury". |
2024-03-04 |
2024-03-07 |
Not clear |
| Dmitrii S Traktirov, Ilya R Nazarov, Valeria S Artemova, Raul R Gainetdinov, Nina S Pestereva, Marina N Karpenk. Alterations in Serotonin Neurotransmission in Hyperdopaminergic Rats Lacking the Dopamine Transporter. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001881. |
in this article we showed that knockout of the gene encoding dat leads not only to a profound dysregulation of dopamine neurotransmission in the striatum but also in the midbrain, prefrontal cortex, hippocampus, medulla oblongata and spinal cord. |
2023-11-25 |
2023-11-28 |
rat |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Ala Nozari, Lars Wiklund, Hari Shanker Sharm. Spinal cord injury induced exacerbation of Alzheimer's disease like pathophysiology is reduced by topical application of nanowired cerebrolysin with monoclonal antibodies to amyloid beta peptide, p-tau and tumor necrosis factor alpha. International review of neurobiology. vol 172. 2023-10-13. PMID:37833015. |
after 48 h of spinal cord injury elevation of amyloid beta peptide, phosphorylated tau (p-tau) and tumor necrosis factor-alpha (tnf-α) was seen in t9 and t12 segments of spinal cord in cerebral cortex, hippocampus and brain stem regions associated with microglial activation as seen by upregulation of iba1 and cd86. |
2023-10-13 |
2023-10-15 |
Not clear |
| Yi-Bo Xu, Yang Sun, Lin-Yu Xiao, Guo-Qing Zhu, Xue Song, Jian-Guo Hu, Qi Q. [Effect of Shionone on Neuron Apoptosis After Spinal Cord Injury in Mice]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023-09-07. PMID:37674468. |
methods c57bl/6 mice were treated to induce the sci model and then assigned into a model group(sci group),a sci+shi group,and a sham surgery(control)group.the basso mouse scale(bms)score was determined to evaluate the recovery of motor function in sci mice.hematoxylin-eosin(he)staining,nissl staining,and immunofluorescence staining were employed to examine the fibrosis,morphological changes of neurons,and neuron apoptosis in the spinal cord tissue of sci mice,respectively.the mouse hippocampal neuronal cell line ht22 was cultured in vitro and then classified into tumor necrosis factor α(tnf-α)induction and shi groups.western blotting was employed to determine the expression of apoptosis-associated proteins.network pharmacology,gene ontology annotation,and kyoto encyclopedia of genes and genomes pathway enrichment were employed to predict the possible molecular targets and signaling pathways of shi in promoting functional recovery from sci.furthermore,the prediction results were verified by in vitro and in vivo experiments. |
2023-09-07 |
2023-10-07 |
mouse |
| Mayra Zancanaro, Dirson J Stein, Bettega C Lopes, Andressa de Souza, Roberta Ströher Toledo, Alessandra H de Souza, Sara M Oliveira, Fernanda Visioli, Paulo R S Sanches, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Preemptive transcranial direct current stimulation induces analgesia, prevents chronic inflammation and fibrosis, and promotes tissue repair in a rat model of postoperative pain. Neuroscience letters. 2023-07-27. PMID:37499743. |
cytokines and bdnf levels were evaluated in the cerebral cortex, hippocampus, brainstem, and spinal cord. |
2023-07-27 |
2023-08-14 |
rat |
| Mayra Zancanaro, Dirson J Stein, Bettega C Lopes, Andressa de Souza, Roberta Ströher Toledo, Alessandra H de Souza, Sara M Oliveira, Fernanda Visioli, Paulo R S Sanches, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Preemptive transcranial direct current stimulation induces analgesia, prevents chronic inflammation and fibrosis, and promotes tissue repair in a rat model of postoperative pain. Neuroscience letters. 2023-07-27. PMID:37499743. |
the results demonstrate that the surgery procedure increased bdnf and il-6 levels in the spinal cord levels in the hippocampus, and decreased il-1β and il-6 levels in the cerebral cortex, il-6 levels in the hippocampus, and il-10 levels in the brainstem and hippocampus. |
2023-07-27 |
2023-08-14 |
rat |
| Mayra Zancanaro, Dirson J Stein, Bettega C Lopes, Andressa de Souza, Roberta Ströher Toledo, Alessandra H de Souza, Sara M Oliveira, Fernanda Visioli, Paulo R S Sanches, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Preemptive transcranial direct current stimulation induces analgesia, prevents chronic inflammation and fibrosis, and promotes tissue repair in a rat model of postoperative pain. Neuroscience letters. 2023-07-27. PMID:37499743. |
in addition, preemptive tdcs was effective in controlling postoperative pain, increasing bdnf, il-6, and il-10 levels in the spinal cord and brainstem, increasing il-1β in the spinal cord, and decreasing il-6 levels in the cerebral cortex and hippocampus, il-1β and il-10 levels in the hippocampus. |
2023-07-27 |
2023-08-14 |
rat |
| Francesco Errico, Luana Gilio, Andrea Mancini, Tommaso Nuzzo, Mario Stampanoni Bassi, Laura Bellingacci, Fabio Buttari, Ettore Dolcetti, Antonio Bruno, Giovanni Galifi, Roberto Furlan, Annamaria Finardi, Anna Di Maio, Massimiliano Di Filippo, Diego Centonze, Alessandro Usiell. Cerebrospinal fluid, brain, and spinal cord levels of L-aspartate signal excitatory neurotransmission abnormalities in multiple sclerosis patients and experimental autoimmune encephalomyelitis mouse model. Journal of neurochemistry. 2023-06-19. PMID:37332201. |
in the present study, we measured by hplc the levels of these amino acids in the cortex, hippocampus, cerebellum, and spinal cord of mice affected by experimental autoimmune encephalomyelitis (eae). |
2023-06-19 |
2023-08-14 |
mouse |
| Dario Pfyffer, Sandra Zimmermann, Kadir Şimşek, Roland Kreis, Patrick Freund, Maryam Sei. Magnetic resonance spectroscopy investigation in the right human hippocampus following spinal cord injury. Frontiers in neurology. vol 14. 2023-05-30. PMID:37251221. |
preclinical studies have shown that cognitive impairments following spinal cord injury (sci), such as impaired spatial memory, are linked to inflammation, neurodegeneration, and reduced neurogenesis in the right hippocampus. |
2023-05-30 |
2023-08-14 |
human |
| Jie Zheng, Feng Yang, Pu-Wei Yuan, Jing-Jie Fan, Xiao-Hui Zheng, Rui Zhu, Yang-le L. [Effect of electroacupuncture on the expression of Iba-1 in spinal dorsal horn and hippocampus of chronic pain rats with knee osteoarthritis]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 5. 2023-05-29. PMID:37247855. |
to observe the effect of electroacupuncture(ea) on pain-ralated behaviors, morphology of hippocampus, concentrations of inflammatory cytokines and expression of ionized calcium binding adapter molecule 1(iba-1) in dorsal horn of the spinal cord and the hippocampus, and brain-derived neurotrophic factor (bdnf) in hippocampus of rats with knee osteoarthritis (koa), so as to explore the mechanism of ea in improving chronic pain of koa. |
2023-05-29 |
2023-08-14 |
rat |
| Franziska T Wunsch, Nils Metzler-Nolte, Carsten Theiss, Veronika Matschk. Defects in Glutathione System in an Animal Model of Amyotrophic Lateral Sclerosis. Antioxidants (Basel, Switzerland). vol 12. issue 5. 2023-05-27. PMID:37237880. |
we analyzed changes in glutathione metabolism in the spinal cord, hippocampus, cerebellum, liver, and blood samples of the als model, wobbler mouse, using qpcr, western blot, hplc, and fluorometric assays. |
2023-05-27 |
2023-08-14 |
mouse |
| Hui Li, Qi-Qin Dan, Yan-Jun Chen, Li Chen, Hong-Tian Zhang, De-Zhi Mu, Ting-Hua Wan. Cellular Localization and Distribution of TGF-β1, GDNF and PDGF-BB in the Adult Primate Central Nervous System. Neurochemical research. 2023-03-28. PMID:36976393. |
the protein levels of tgf-β1, pdgf-bb, and gdnf in the cerebral cortex, cerebellum, hippocampus, and spinal cord were analyzed by western blotting. |
2023-03-28 |
2023-08-14 |
human |
| Hui Li, Qi-Qin Dan, Yan-Jun Chen, Li Chen, Hong-Tian Zhang, De-Zhi Mu, Ting-Hua Wan. Cellular Localization and Distribution of TGF-β1, GDNF and PDGF-BB in the Adult Primate Central Nervous System. Neurochemical research. 2023-03-28. PMID:36976393. |
besides, tgf-β1, pdgf-bb, and gdnf were localized in the astrocytes and microglia of spinal cord and hippocampus, and their expression was mainly found in the cytoplasm and primary dendrites. |
2023-03-28 |
2023-08-14 |
human |
| Bin Xi, Jieping Fu, Dengfeng Wan, Zhiping Xi. Ginsenoside Rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling. Neuroreport. vol 34. issue 5. 2023-03-07. PMID:36881751. |
ginsenoside rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling. |
2023-03-07 |
2023-08-14 |
rat |
| Bin Xi, Jieping Fu, Dengfeng Wan, Zhiping Xi. Ginsenoside Rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling. Neuroreport. vol 34. issue 5. 2023-03-07. PMID:36881751. |
we previously demonstrated that spinal cord injury (sci) induced hippocampus injury and depression in rodents. |
2023-03-07 |
2023-08-14 |
rat |
| Qaisar Ali Khan, Rohail Khan, Ravina Verma, Suchi D Shah, Bhavana Vattikuti, Aleena Z Khan, Andia Shahzadi, Parsa Abdi, Michelle Anthony, Christopher S Farkouh, Matthew Farkouh, Natalia Santiago, David Zepeda, Andrew Nune. Non-syndromic Intellectual Disability: An Experimental In-Depth Exploration of Inheritance Pattern, Phenotypic Presentation, and Genomic Composition. Cureus. vol 15. issue 1. 2023-02-27. PMID:36843831. |
three genes, cdk5r1, omg, and ev12a, were found on chromosome 17q11.2-q12 region of affected individuals in family a with high expression in the frontal cortex of the brain, hippocampus, and spinal cord, respectively. |
2023-02-27 |
2023-08-14 |
Not clear |