All Relations between striatum and Multiple System Atrophy

Publication Sentence Publish Date Extraction Date Species
Shojiro Ichimata, Koji Yoshida, Jun Li, Ekaterina Rogaeva, Anthony E Lang, Gabor G Kovac. The molecular spectrum of amyloid-beta (Aβ) in neurodegenerative diseases beyond Alzheimer's disease. Brain pathology (Zurich, Switzerland). 2023-08-31. PMID:37652560. we analyzed aβ deposition in the temporal cortex and striatum in 116 autopsies, including lewy body disease (lbd; n = 51), multiple system atrophy (msa; n = 10), frontotemporal lobar degeneration-tdp-43 (ftld-tdp; n = 16), and progressive supranuclear palsy (psp; n = 39). 2023-08-31 2023-09-07 Not clear
Hao Chen, Yajie Li, Jingwen Gao, Qi Cheng, Lei Liu, Rong Ca. Activation of Pgk1 Results in Reduced Protein Aggregation in Diverse Neurodegenerative Conditions. Molecular neurobiology. 2023-05-30. PMID:37249790. through in vivo studies, we examined neuron-specific overexpression of tau in drosophila, mouse models of app/ps1 alzheimer's disease (ad), and a rat model of multiple system atrophy (msa) via the viral expression of α-synuclein in the striatum. 2023-05-30 2023-08-14 mouse
Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Sandrine Camus, Gregory Porras, Marie-Laure Thiolat, Ines Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, Michele Morari, Wassilios G Meissner, María Trinidad Herrero, Miquel Vila, Jose A Obeso, Erwan Bezard, Benjamin Deha. Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology. Brain : a journal of neurology. 2022-03-14. PMID:35285474. to evaluate the possible pathogenic role of glial cytoplasmic inclusions, we inoculated glial cytoplasmic inclusion-containing brain fractions obtained from multiple system atrophy patients into the striatum of non-human primates. 2022-03-14 2023-08-13 Not clear
Alain Ndayisaba, Kurt Jellinger, Thomas Berger, Gregor K Wennin. TNFα inhibitors as targets for protective therapies in MSA: a viewpoint. Journal of neuroinflammation. vol 16. issue 1. 2019-08-12. PMID:30975183. multiple system atrophy (msa) is a unique and fatal α-synucleinopathy associated with oligodendroglial inclusions and secondary neurodegeneration affecting striatum, substantia nigra, pons, and cerebellum. 2019-08-12 2023-08-13 Not clear
Fares Bassil, Marie-Hélène Canron, Anne Vital, Erwan Bezard, Yazhou Li, Nigel H Greig, Seema Gulyani, Dimitrios Kapogiannis, Pierre-Olivier Fernagut, Wassilios G Meissne. Insulin resistance and exendin-4 treatment for multiple system atrophy. Brain : a journal of neurology. vol 140. issue 5. 2017-10-30. PMID:28334990. we also observed insulin resistance in the striatum of transgenic multiple system atrophy mice and further demonstrate that the glucagon-like peptide-1 analogue exendin-4, a well-tolerated and federal drug agency-approved antidiabetic drug, has positive effects on insulin resistance and monomeric α-synuclein load in the striatum, as well as survival of nigral dopamine neurons. 2017-10-30 2023-08-13 mouse
Thomas E Cope, Manon Grube, Baldev Singh, David J Burn, Timothy D Griffith. The basal ganglia in perceptual timing: timing performance in Multiple System Atrophy and Huntington's disease. Neuropsychologia. vol 52. 2014-08-18. PMID:24135486. test groups comprised individuals with multiple system atrophy, a disorder in which similar pathology can produce clinical deficits associated with dysfunction of the cerebellum (msa-c, n = 8) or striatum (msa-p, n = 10), and early symptomatic huntington's disease (hd, n = 14). 2014-08-18 2023-08-12 Not clear
Michael Nocker, Klaus Seppi, Eveline Donnemiller, Irene Virgolini, Gregor K Wenning, Werner Poewe, Christoph Scherfle. Progression of dopamine transporter decline in patients with the Parkinson variant of multiple system atrophy: a voxel-based analysis of [123I]β-CIT SPECT. European journal of nuclear medicine and molecular imaging. vol 39. issue 6. 2012-09-05. PMID:22460689. we characterized the progression of dopamine transporter (dat) decline in the striatum and extrastriatal regions including the midbrain and pons of patients with the parkinson variant of multiple system atrophy (msa-p) and compared longitudinally collected spect results with those in a cohort of patients with parkinson's disease (pd). 2012-09-05 2023-08-12 Not clear
Hui You, Jue Wang, Han Wang, Yu-Feng Zang, Fu-Ling Zheng, Chun-Ling Meng, Feng Fen. Altered regional homogeneity in motor cortices in patients with multiple system atrophy. Neuroscience letters. vol 502. issue 1. 2012-01-05. PMID:21798310. typical histopathological findings of multiple system atrophy (msa) have been observed in motor related cortices, in addition to the common areas of the striatum, substantia nigra, olivopontocerebellar pathways, the intermediolateral cell columns of the spinal cord, and the cerebellum. 2012-01-05 2023-08-12 Not clear
Mario Mascalchi, Alessandra Vell. Magnetic resonance and nuclear medicine imaging in ataxias. Handbook of clinical neurology. vol 103. 2011-12-06. PMID:21827882. pet and spect with radiotracers able to assess the nigrostriatal system or the density of d2 dopamine receptors in the striatum are increasingly used in patients with adult-onset sporadic ataxia for the differential diagnosis between multiple system atrophy in which overt striatal abnormalities are found and idiopathic late-onset cerebellar ataxia in which no abnormality is detected. 2011-12-06 2023-08-12 Not clear
M Otsuka, T Taniwak. [Functional imaging for disorders of basal ganglia]. Rinsho shinkeigaku = Clinical neurology. vol 39. issue 1. 1999-09-15. PMID:10377793. the 18f-dopa uptake in the striatum also decreased in cases of multiple system atrophy and progressive supranuclear palsy, but there was no difference in the uptake between the caudate and the putamen. 1999-09-15 2023-08-12 Not clear
Y Kawamoto, S Nakamura, I Akiguchi, J Kimur. Increased brain-derived neurotrophic factor-containing axons in the basal ganglia of patients with multiple system atrophy. Journal of neuropathology and experimental neurology. vol 58. issue 7. 1999-07-27. PMID:10411346. to investigate whether the abnormal expression of bdnf occurs in the basal ganglia of patients with parkinson disease (pd) and multiple system atrophy (msa), we compared the bdnf levels in the striatum and globus pallidus of patients with pd or msa to controls using immunohistochemistry. 1999-07-27 2023-08-12 Not clear
S C Schwarz, T Seufferlein, S Liptay, R M Schmid, K Kasischke, O J Foster, S Daniel, J Schwar. Microglial activation in multiple system atrophy: a potential role for NF-kappaB/rel proteins. Neuroreport. vol 9. issue 13. 1999-06-07. PMID:9804310. we investigated the nuclear presence of rela, the 65 kda subunit of the nf-kb/rela family in striatum and brain stem of patients with multiple system atrophy. 1999-06-07 2023-08-12 Not clear
S Gilman, K A Frey, R A Koeppe, L Junck, R Little, T M Vander Borght, M Lohman, S Martorello, L C Lee, D M Jewett, M R Kilbour. Decreased striatal monoaminergic terminals in olivopontocerebellar atrophy and multiple system atrophy demonstrated with positron emission tomography. Annals of neurology. vol 40. issue 6. 1997-02-13. PMID:9007093. specific binding in the striatum was significantly reduced in the multiple system atrophy patients as compared with the normal control group, with average reductions of 61% in the caudate nucleus (p = 0.002) and 58% in the putamen (p = 0.009). 1997-02-13 2023-08-12 human
H Ito, H Kusaka, S Matsumoto, T Ima. Striatal efferent involvement and its correlation to levodopa efficacy in patients with multiple system atrophy. Neurology. vol 47. issue 5. 1996-12-18. PMID:8909445. irrespective of the clinical form of multiple system atrophy, the immunoreactivity with the antibodies was reduced at the dorsolateral portion of the striatum and the ventrolateral portions of the globus pallidus and of the substantia nigra. 1996-12-18 2023-08-12 human
H Ito, H Kusaka, S Matsumoto, T Ima. Striatal efferent involvement and its correlation to levodopa efficacy in patients with multiple system atrophy. Neurology. vol 47. issue 5. 1996-12-18. PMID:8909445. we report an immunohistochemical investigation of the striatal efferents in the striatum, globus pallidus, and substantia nigra of five patients with multiple system atrophy (msa): olivopontocerebellar atrophy (2), striatonigral degeneration (2), and shy-drager syndrome (1). 1996-12-18 2023-08-12 human
E van Royen, N F Verhoeff, J D Speelman, E C Wolters, M A Kuiper, A G Jansse. Multiple system atrophy and progressive supranuclear palsy. Diminished striatal D2 dopamine receptor activity demonstrated by 123I-IBZM single photon emission computed tomography. Archives of neurology. vol 50. issue 5. 1993-06-09. PMID:8489409. to measure d2 dopamine receptors in the striatum in patients with multiple system atrophy and progressive supranuclear palsy by i 3-iodo-6-methoxybenzamide labeled with iodine i 123 (123i-ibzm) single photon emission computed tomography and differentiate them from control subjects. 1993-06-09 2023-08-12 human
D T Dexter, P Jenner, A H Schapira, C D Marsde. Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Annals of neurology. vol 32 Suppl. 1992-09-18. PMID:1510387. we measured levels of iron, copper, zinc, manganese, and ferritin in postmortem tissue from patients with progressive supranuclear palsy (psp) and multiple system atrophy (msa) (which shows pathology in the sn and striatum) and huntington's disease (hd) (which shows pathological changes in the striatum, compared with control subjects). 1992-09-18 2023-08-11 human