| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ferron F Ocampo, Carlo Sacdalan, Suteeraporn Pinyakorn, Misti Paudel, Tanyaporn Wansom, Nathornsorn Poltubtim, Somchai Sriplienc, Nittaya Phanuphak, Robert Paul, Denise Hsu, Donn Colby, Lydie Trautmann, Serena Spudich, Phillip Cha. Neuropsychiatric and Laboratory Outcomes of Hepatitis C Treatment in an Early-Treated HIV Cohort in Thailand. Research square. 2024-04-22. PMID:38645141. |
following svr, aspartate transferase (ast) and alanine transaminase (alt) decreased (p < 0.001), while total cholesterol, low-density lipoprotein, and triglycerides increased (p < 0.01). |
2024-04-22 |
2024-04-24 |
human |
| Zekang Su, Yali Zhang, Shiyi Hong, Qiaojian Zhang, Jiayu Xu, Guiping Hu, Xiaojun Zhu, Fang Yuan, Shanfa Yu, Tianchen Wang, Guang Ji. Relationships between blood chromium exposure and liver injury: Exploring the mediating role of systemic inflammation in a chromate-exposed population. Journal of environmental sciences (China). vol 143. 2024-04-21. PMID:38644019. |
to address this, we conducted a follow-up study of 590 visits from 305 participants to investigate the associations of blood cr with biomarkers for liver injury, including serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tbil), and direct bilirubin (dbil), and to evaluate the mediating effects of systemic inflammation. |
2024-04-21 |
2024-04-24 |
human |
| Deniz Gür-Altunay, Pınar Yürük-Ataso. How Successful Are APRI and FIB-4 Scores in Predicting Liver Fibrosis in Chronic Hepatitis B Patients? Infectious diseases & clinical microbiology. vol 5. issue 4. 2024-04-18. PMID:38633858. |
we aimed to evaluate the correlation of fibrosis severity in liver biopsies, the gold standard for the diagnosis of patients with chronic hepatitis b (chb), using noninvasive methods such as the aspartate aminotransferase (ast)-to-platelet ratio index (apri) and fibrosis-4 score (fib-4). |
2024-04-18 |
2024-04-20 |
Not clear |
| Lu Zhang, Ying Liu, Qiongyi Zhang, Weiyu Yao, Zenghui Zhao, Xiao Wang, Yongzhan Bao, Wanyu Sh. Salvia miltiorrhiza polysaccharide mitigates AFB1-induced liver injury in rabbits. Ecotoxicology and environmental safety. vol 276. 2024-04-18. PMID:38636259. |
smp reduced aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp) levels in serum, ameliorating afb1-induced hepatic pathological changes. |
2024-04-18 |
2024-04-21 |
cat |
| Victor Nehmi-Filho, Jessica Alves de Freitas, Lucas Augusto Franco, Roberta Cristina Martins, José Antônio Orellana Turri, Aline Boveto Santamarina, Joyce Vanessa da Silva Fonseca, Ester Cerdeira Sabino, Bruna Carvalho Moraes, Erica Souza, Gilson Masahiro Murata, Silvia Figueiredo Costa, Paulo Sérgio Alcântara, José Pinhata Otoch, Ana Flávia Marçal Pesso. Modulation of the gut microbiome and Firmicutes phylum reduction by a nutraceutical blend in the obesity mouse model and overweight humans: A double-blind clinical trial. Food science & nutrition. vol 12. issue 4. 2024-04-17. PMID:38628220. |
overweight and obesity are closely linked to gut dysbiosis/dysmetabolism and disrupted de-ritis ratio [aspartate aminotransferase (ast)/alanine aminotransferase (alt) ratio], which may contribute to chronic noncommunicable diseases onset. |
2024-04-17 |
2024-04-19 |
mouse |
| Xixi Zeng, Ling Chen, Bo Zhen. Extrusion and chlorogenic acid treatment increase the ordered structure and resistant starch levels in rice starch with amelioration of gut lipid metabolism in obese rats. Food & function. 2024-04-16. PMID:38623646. |
compared to a physical mixture of starch and chlorogenic acid (cga + s), cga-es showed a more potent effect in alleviating lipid metabolism disorders, manifesting as reduced levels of blood glucose, serum total cholesterol (tc), triglycerides (tg), aspartate aminotransferase (ast), alanine transaminase (alt) and alkaline phosphatase (akp), as well as body weight. |
2024-04-16 |
2024-04-18 |
rat |
| Zhi Qin, Min Zho. [Tanshinone Ⅱ_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 6. 2024-04-15. PMID:38621946. |
a biochemical analyzer was used to measure the content of aspartate aminotransferase(ast), alaninl aminotransferase(alt), total cholesterol(tc), and triglycerides(tg). |
2024-04-15 |
2024-04-18 |
rat |
| Mei-Ting Tai, Chen-Fang Zhang, Chao-Wen Fan, Wei-Yi Tian, Qi Yu, Yan Fu, De-Li Xia, Meng-Lan Mao, Dan-Lu Shi, Zun-Li K. [Intervention effect of Erchen Decoction on methionine and choline deficient diet-induced non-alcoholic steatohepatitis in mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 5. 2024-04-15. PMID:38621978. |
the serum was used to detect the levels of alanine aminotransferase(alt), aspartate aminotransaminase(ast), interleukin-1β(il-1β), interleukin-6(il-6), interleukin-10(il-10), and tumor necrosis factor-α(tnf-α). |
2024-04-15 |
2024-04-18 |
mouse |
| Alaa El-Din H Sayed, Walaa F A Emeish, Karima A Bakry, Zeinab Al-Amgad, Jae-Seong Lee, Salwa Mansou. Polystyrene nanoplastic and engine oil synergistically intensify toxicity in Nile tilapia, Oreochromis niloticus : Polystyrene nanoplastic and engine oil toxicity in Nile tilapia. BMC veterinary research. vol 20. issue 1. 2024-04-15. PMID:38622626. |
both malondialdehyde (mda) and aspartate aminotransferase (ast) showed a significant elevation only in the combination group. |
2024-04-15 |
2024-04-18 |
Not clear |
| Saiqa Ishtiaq, Saira Rehman, Sairah Hafeez Kamran, Zahid Mehmood Akhtar, Mai Albaik, Sameh S Elhad. Metabolic profiling of Verbena bonariensis L. extract by LC/MS and evaluation of the hepatoprotective potential with isoniazid- and rifampicin-induced hepatotoxicity in rats. Archiv der Pharmazie. 2024-04-12. PMID:38607964. |
different biochemical parameters such as aspartate transaminase (ast), alanine transaminase (alt), and alkaline phosphatase (alp), bilirubin, and total protein levels were used to assess liver functions. |
2024-04-12 |
2024-04-15 |
rat |
| R Al-Barwani, E Sarha. BREAST CANCER-MODULATED OMENTIN AND VASPIN PLASMA LEVELS. Georgian medical news. issue 347. 2024-04-12. PMID:38609116. |
additionally, breast cancer patients exhibited significantly higher levels of aspartate aminotransferase (ast), alkaline phosphatase (alp), and alanine transaminase (alt) compared to the control group (p<0.05). |
2024-04-12 |
2024-04-15 |
Not clear |
| R Al-Barwani, E Sarha. BREAST CANCER-MODULATED OMENTIN AND VASPIN PLASMA LEVELS. Georgian medical news. issue 347. 2024-04-12. PMID:38609116. |
additionally, liver function testing indicated lower levels of alanine transaminase (alt), alkaline phosphatase (alp), and aspartate aminotransferase (ast) in breast cancer patients. |
2024-04-12 |
2024-04-15 |
Not clear |
| Mengyang Yu, Chengying Zhang, Sitong Wan, Yang Lu, Yufei Wang, Ting Liu, Huimin Wang, Wei Chen, Yahua Li. NEW PREDICTIVE BIOMARKERS FOR SCREENING COVID-19 PATIENTS WITH RHABDOMYOLYSIS IN COMBINATION WITH CYSTATIN C. Shock (Augusta, Ga.). vol 61. issue 4. 2024-04-11. PMID:38010067. |
multivariate analysis revealed that sao 2 (hazard ratio [hr], 0.946; 95% confidence interval [ci], 0.906-0.987; p = 0.011), cysc (hr, 2.124; 95% ci, 1.223-3.689; p = 0.008), aspartate aminotransferase (ast) (hr, 1.009; 95% ci, 1.000-1.018; p = 0.041), and hypersensitive c-reactive protein (hr, 1.005; 95% ci, 1.000-1.010; p = 0.045) were significantly associated with survivals. |
2024-04-11 |
2024-04-14 |
human |
| Marcela C Sena, Fábio C Sterzelecki, Paola Fabiana F Gomes, Helen Cristiane A Souza, Nuno Filipe A Correia de Melo, J Natividade, B Baldisserotto, Glauber David A Palheta, Simone do Socorro D Santo. Maximum storage time of refrigerated blood and frozen plasma samples from tambaqui, Colossoma macropomum. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2024-04-11. PMID:38604560. |
the parameters analyzed were hematocrit (ht), hemoglobin content (hb), total erythrocytes (rbc), total (wbc) and differential leukocytes, total thrombocytes (tc), glucose content (glc), total protein (tp), triglyceride content (tg), total cholesterol (cot), and the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2024-04-11 |
2024-04-14 |
Not clear |
| Manik Chandra Shill, Heba A S El-Nashar, Patricia Prova Mollick, Rabindra Nath Acharyya, Silvia Afrin, Hemayet Hossain, Shimul Halder, Muhammad Torequl Islam, Md Shimul Bhuia, Hasan Mahmud Reza, Mohamed El-Shazly, Mohammad S Mubara. Longevity Spinach (Gynura procumbens) Ameliorated Oxidative Stress and Inflammatory Mediators in Cisplatin-Induced Organ Dysfunction in Rats: Comprehensive in vivo and in silico Studies. Chemistry & biodiversity. 2024-04-10. PMID:38361048. |
although gp extract significantly ameliorated cp-mediated hepatorenal biomarkers like alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), creatinine, and blood urea nitrogen (bun) levels in a dose-dependent manner, gp extract at 150 mg/kg dose normalized hepatorenal biomarkers alp (45.11 u/l), alt (34 u/l), ast (29 u/l), creatinine (10.3 mg/dl) and bun (11.19 mg/dl) while comparing to control and disease group. |
2024-04-10 |
2024-04-12 |
rat |
| Chun Zhang, Feng Lin, Deng-Fang Guo, Qing-Lin Wang, De-Xian Xiao, Jian-Yuan Lin, Shi Che. Assessing the causal link between liver function and acute pancreatitis: A Mendelian randomisation study. PloS one. vol 19. issue 4. 2024-04-08. PMID:38578756. |
conversely, the results for alkaline phosphatase (alp) (or = 0.997, 95%ci: 0.992-1.002, p = 0.197) and aspartate aminotransferase (ast) (or = 0.939, 95%ci: 0.794-1.111, p = 0.464) did not show a causal effect on acute pancreatitis. |
2024-04-08 |
2024-04-10 |
Not clear |
| Yu Zhang, Chui Mei Ong, Kara Lynch, Javier Waksman, Alan H B W. Serum microRNA‑122 for assessment of acute liver injury in patients with extensive skeletal muscle damage. Laboratory medicine. 2024-04-05. PMID:38578664. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities are increased in other conditions, such as acute skeletal muscle injury (asmi). |
2024-04-05 |
2024-04-07 |
Not clear |
| Hiroaki Watanabe, Keita Hirai, Yuka Nakazawa, Ayaka Koike, Hiroyuki Tsuchiya, Takafumi Nait. Effect of Enoxaparin and Daikenchuto Coadministration on Hepatic Disorder Markers in Gynecological Cancer Patients after Abdominal Surgery. Biological & pharmaceutical bulletin. vol 47. issue 4. 2024-04-03. PMID:38569843. |
this study defined hepatic disorders as an increase in aspartate aminotransferase (ast) or alanine aminotransaminase (alt) levels above the reference values, using 1-h postoperative values as the baseline. |
2024-04-03 |
2024-04-06 |
Not clear |
| Wenjie Yi, Junwen Shi, Liying Wang, Dongxuan Wang, Yiting Wang, Jingwen Song, Lili Xin, Fei Jian. Maternal PFOS exposure in mice induces hepatic lipid accumulation and inflammation in adult female offspring: Involvement of microbiome-gut-liver axis and autophagy. Journal of hazardous materials. vol 470. 2024-04-02. PMID:38565010. |
the results suggested that maternal pfos exposure increased serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and induced f4/80 |
2024-04-02 |
2024-04-05 |
mouse |
| Qiwen Yu, Jiye Li, Mengwei Cui, Chaopeng Mei, Qianqian He, Xiaoxiao D. 6-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway. Scientific reports. vol 14. issue 1. 2024-04-02. PMID:38565569. |
the results show that 6-gingerol decreased serum alanine aminotransferase (alt), aspartate aminotransferase (ast) levels, liver necrosis, inflammatory cytokines il-1β, il-6, mcp-1, tnf-α expression, ly6g+ inflammatory cell infiltration, protein phosphorylation of nf-κb signaling pathway, terminal deoxynucleotidyl transferase dutp nick-end labeling (tunel) positive cells, cell apoptosis rate, the protein expression of pro-apoptotic protein bax and c-caspase3, increased cell viability, and expression of anti-apoptotic protein bcl-2. |
2024-04-02 |
2024-04-05 |
mouse |